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The role of Criterion A2 in the DSM-IV diagnosis of post-traumatic stress disorder

Identifieur interne : 007350 ( Main/Merge ); précédent : 007349; suivant : 007351

The role of Criterion A2 in the DSM-IV diagnosis of post-traumatic stress disorder

Auteurs : Elie George Karam [Liban] ; Gavin Andrews [Australie] ; Evelyn Bromet [États-Unis] ; Maria Petukhova [États-Unis] ; Ayelet Meron Ruscio [États-Unis] ; Mariana Salamoun [Liban] ; Nancy Sampson [États-Unis] ; Dan J. Stein [Afrique du Sud] ; Jordi Alonso [Espagne] ; Laura Helena Andrade [Brésil] ; Matthias Angermeyer [Autriche] ; Koen Demyttenaere [Belgique] ; Giovanni De Girolamo [Italie] ; Ron De Graaf [Pays-Bas] ; Silvia Florescu [Roumanie] ; Oye Gureje [Nigeria] ; Debra Kaminer [Afrique du Sud] ; Roman Kotov [États-Unis] ; Sing Lee [République populaire de Chine] ; Jean Pierre Lepine ; Maria Elena Medina Mora [Mexique] ; Mark A. Oakley Browne [Australie] ; José Posada-Villa [Colombie] ; Rajesh Sagar [Inde] ; Arieh Y. Shalev [Israël] ; Tadashi Takeshima [Japon] ; Toma Tomov [Bulgarie] ; Ronald C. Kessler [États-Unis]

Source :

RBID : PMC:3228599

Abstract

Background

Controversy exists about the utility of DSM-IV post-traumatic stress disorder (PTSD) Criterion A2: that exposure to a potentially traumatic experience (PTE; PTSD Criterion A1) is accompanied by intense fear, helplessness, or horror.

Methods

Lifetime DSM-IV PTSD was assessed with the Composite International Diagnostic Interview in community surveys of 52,826 respondents across 21 countries in the World Mental Health Surveys.

Results

37.6% of 28,490 representative PTEs reported by respondents met Criterion A2, a proportion higher than the proportions meeting other criteria (B-F; 5.4-9.6%). Conditional prevalence of meeting all other criteria for a diagnosis of PTSD given a PTE was significantly higher in the presence (9.7%) than absence (0.1%) of A2. However, as only 1.4% of respondents who met all other criteria failed A2, the estimated prevalence of PTSD increased only slightly (from 3.64% to 3.69%) when A2 was not required for diagnosis. PTSD with or without Criterion A2 did not differ in persistence or predicted consequences (subsequent suicidal ideation or secondary disorders) depending on presence-absence of A2. Furthermore, as A2 was by far the most commonly reported symptom of PTSD, initial assessment of A2 would be much less efficient than screening other criteria in quickly ruling out a large proportion of non-cases.

Conclusion

Removal of A2 from the DSM-IV criterion set would reduce the complexity of diagnosing PTSD while not substantially increasing the number of people who qualify for diagnosis. A2 should consequently be reconceptualized as a risk factor for PTSD rather than as a diagnostic requirement.


Url:
DOI: 10.1016/j.biopsych.2010.04.032
PubMed: 20599189
PubMed Central: 3228599

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PMC:3228599

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</author>
<author>
<name sortKey="Sampson, Nancy" sort="Sampson, Nancy" uniqKey="Sampson N" first="Nancy" last="Sampson">Nancy Sampson</name>
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<nlm:aff id="A4">Department of Health Care Policy, Harvard Medical School, Boston, MA USA</nlm:aff>
<country>États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Health Care Policy, Harvard Medical School, Boston</wicri:cityArea>
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</author>
<author>
<name sortKey="Stein, Dan J" sort="Stein, Dan J" uniqKey="Stein D" first="Dan J." last="Stein">Dan J. Stein</name>
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<nlm:aff id="A6">Department of Psychiatry, Groote Schuur Hospital, Cape Town, South Africa</nlm:aff>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>Department of Psychiatry, Groote Schuur Hospital, Cape Town</wicri:regionArea>
<wicri:noRegion>Cape Town</wicri:noRegion>
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</author>
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<name sortKey="Alonso, Jordi" sort="Alonso, Jordi" uniqKey="Alonso J" first="Jordi" last="Alonso">Jordi Alonso</name>
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<nlm:aff id="A7">Health Services Research Unit, Institut Municipal d’Investigació Mèdica (IMIM-Hospital del Mar), CIBER en Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Health Services Research Unit, Institut Municipal d’Investigació Mèdica (IMIM-Hospital del Mar), CIBER en Epidemiología y Salud Pública (CIBERESP), Barcelona</wicri:regionArea>
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<settlement type="city">Barcelone</settlement>
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<name sortKey="Andrade, Laura Helena" sort="Andrade, Laura Helena" uniqKey="Andrade L" first="Laura Helena" last="Andrade">Laura Helena Andrade</name>
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<nlm:aff id="A8">Section of Psychiatric Epidemiology- LIM 23 Department and Institute of Psychiatry School of Medicine University of São Paulo São Paulo, Brazil</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Section of Psychiatric Epidemiology- LIM 23 Department and Institute of Psychiatry School of Medicine University of São Paulo São Paulo</wicri:regionArea>
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<author>
<name sortKey="Angermeyer, Matthias" sort="Angermeyer, Matthias" uniqKey="Angermeyer M" first="Matthias" last="Angermeyer">Matthias Angermeyer</name>
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<nlm:aff id="A9">Center for Public Mental Health, Gösing am Wagram, Austria</nlm:aff>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Center for Public Mental Health, Gösing am Wagram</wicri:regionArea>
<wicri:noRegion>Gösing am Wagram</wicri:noRegion>
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</author>
<author>
<name sortKey="Demyttenaere, Koen" sort="Demyttenaere, Koen" uniqKey="Demyttenaere K" first="Koen" last="Demyttenaere">Koen Demyttenaere</name>
<affiliation wicri:level="1">
<nlm:aff id="A10">Department of Psychiatry, University Hospital Gasthuisberg, Leuven, Belgium</nlm:aff>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea>Department of Psychiatry, University Hospital Gasthuisberg, Leuven</wicri:regionArea>
<wicri:noRegion>Leuven</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="De Girolamo, Giovanni" sort="De Girolamo, Giovanni" uniqKey="De Girolamo G" first="Giovanni" last="De Girolamo">Giovanni De Girolamo</name>
<affiliation wicri:level="1">
<nlm:aff id="A11">IRCCS Centro S. Giovanni di Dio Fatebenefratelli, Brescia, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>IRCCS Centro S. Giovanni di Dio Fatebenefratelli, Brescia</wicri:regionArea>
<wicri:noRegion>Brescia</wicri:noRegion>
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</author>
<author>
<name sortKey="De Graaf, Ron" sort="De Graaf, Ron" uniqKey="De Graaf R" first="Ron" last="De Graaf">Ron De Graaf</name>
<affiliation wicri:level="3">
<nlm:aff id="A12">Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Institute of Mental Health and Addiction, Utrecht</wicri:regionArea>
<placeName>
<settlement type="city">Utrecht</settlement>
<region nuts="2" type="province">Utrecht (province)</region>
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<name sortKey="Florescu, Silvia" sort="Florescu, Silvia" uniqKey="Florescu S" first="Silvia" last="Florescu">Silvia Florescu</name>
<affiliation wicri:level="1">
<nlm:aff id="A13">Public Health Research and Evidence Based Medicine Department, National School of Public Health and Health Services Management, Bucharest, Romania</nlm:aff>
<country xml:lang="fr">Roumanie</country>
<wicri:regionArea>Public Health Research and Evidence Based Medicine Department, National School of Public Health and Health Services Management, Bucharest</wicri:regionArea>
<wicri:noRegion>Bucharest</wicri:noRegion>
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<author>
<name sortKey="Gureje, Oye" sort="Gureje, Oye" uniqKey="Gureje O" first="Oye" last="Gureje">Oye Gureje</name>
<affiliation wicri:level="1">
<nlm:aff id="A14">University College Hospital, Prince of Wales Ibadan, Nigeria</nlm:aff>
<country xml:lang="fr">Nigeria</country>
<wicri:regionArea>University College Hospital, Prince of Wales Ibadan</wicri:regionArea>
<wicri:noRegion>Prince of Wales Ibadan</wicri:noRegion>
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<author>
<name sortKey="Kaminer, Debra" sort="Kaminer, Debra" uniqKey="Kaminer D" first="Debra" last="Kaminer">Debra Kaminer</name>
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<nlm:aff id="A15">Department of Psychology, University of Cape Town, South Africa</nlm:aff>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>Department of Psychology, University of Cape Town</wicri:regionArea>
<wicri:noRegion>University of Cape Town</wicri:noRegion>
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<author>
<name sortKey="Kotov, Roman" sort="Kotov, Roman" uniqKey="Kotov R" first="Roman" last="Kotov">Roman Kotov</name>
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<nlm:aff id="A16">Department of Psychiatry, Stony Brook University, New York, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry, Stony Brook University, New York</wicri:regionArea>
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<region type="state">État de New York</region>
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<author>
<name sortKey="Lee, Sing" sort="Lee, Sing" uniqKey="Lee S" first="Sing" last="Lee">Sing Lee</name>
<affiliation wicri:level="4">
<nlm:aff id="A17">Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong</wicri:regionArea>
<orgName type="university">Université chinoise de Hong Kong</orgName>
<placeName>
<settlement type="city">Sha Tin</settlement>
</placeName>
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</author>
<author>
<name sortKey="Lepine, Jean Pierre" sort="Lepine, Jean Pierre" uniqKey="Lepine J" first="Jean Pierre" last="Lepine">Jean Pierre Lepine</name>
<affiliation>
<nlm:aff id="A18">INSERM U 705, CNRS UMR 7157, University Paris Diderot, Hôpital Lariboisière Fernand Widal, Assistance Publique Hôpitaux de Paris, Paris France</nlm:aff>
<wicri:noCountry code="subfield">Paris France</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Mora, Maria Elena Medina" sort="Mora, Maria Elena Medina" uniqKey="Mora M" first="Maria Elena Medina" last="Mora">Maria Elena Medina Mora</name>
<affiliation wicri:level="1">
<nlm:aff id="A19">National Institute of Psychiatry Ramon de la Fuente, Mexico City, Mexico</nlm:aff>
<country xml:lang="fr">Mexique</country>
<wicri:regionArea>National Institute of Psychiatry Ramon de la Fuente, Mexico City</wicri:regionArea>
<wicri:noRegion>Mexico City</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Browne, Mark A Oakley" sort="Browne, Mark A Oakley" uniqKey="Browne M" first="Mark A. Oakley" last="Browne">Mark A. Oakley Browne</name>
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<nlm:aff id="A20">The Discipline of Psychiatry, the University of Tasmania, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>The Discipline of Psychiatry, the University of Tasmania</wicri:regionArea>
<wicri:noRegion>the University of Tasmania</wicri:noRegion>
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</author>
<author>
<name sortKey="Posada Villa, Jose" sort="Posada Villa, Jose" uniqKey="Posada Villa J" first="José" last="Posada-Villa">José Posada-Villa</name>
<affiliation wicri:level="1">
<nlm:aff id="A21">Colegio Mayor de Cundinamarca University, Bogota, Colombia</nlm:aff>
<country xml:lang="fr">Colombie</country>
<wicri:regionArea>Colegio Mayor de Cundinamarca University, Bogota</wicri:regionArea>
<wicri:noRegion>Bogota</wicri:noRegion>
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<name sortKey="Sagar, Rajesh" sort="Sagar, Rajesh" uniqKey="Sagar R" first="Rajesh" last="Sagar">Rajesh Sagar</name>
<affiliation wicri:level="1">
<nlm:aff id="A22">Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India</nlm:aff>
<country xml:lang="fr">Inde</country>
<wicri:regionArea>Department of Psychiatry, All India Institute of Medical Sciences, New Delhi</wicri:regionArea>
<wicri:noRegion>New Delhi</wicri:noRegion>
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</author>
<author>
<name sortKey="Shalev, Arieh Y" sort="Shalev, Arieh Y" uniqKey="Shalev A" first="Arieh Y." last="Shalev">Arieh Y. Shalev</name>
<affiliation wicri:level="1">
<nlm:aff id="A23">Department of Psychiatry, Hadassah University Hospital, Jerusalem, Israel</nlm:aff>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Department of Psychiatry, Hadassah University Hospital, Jerusalem</wicri:regionArea>
<wicri:noRegion>Jerusalem</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Takeshima, Tadashi" sort="Takeshima, Tadashi" uniqKey="Takeshima T" first="Tadashi" last="Takeshima">Tadashi Takeshima</name>
<affiliation wicri:level="1">
<nlm:aff id="A24">National Institute of Mental Health, National Center of Neurology and Psychiatry, Japan</nlm:aff>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>National Institute of Mental Health, National Center of Neurology and Psychiatry</wicri:regionArea>
<wicri:noRegion>National Center of Neurology and Psychiatry</wicri:noRegion>
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</author>
<author>
<name sortKey="Tomov, Toma" sort="Tomov, Toma" uniqKey="Tomov T" first="Toma" last="Tomov">Toma Tomov</name>
<affiliation wicri:level="3">
<nlm:aff id="A25">Department of Psychiatry, New Bulgarian University, Sofia, Bulgaria</nlm:aff>
<country xml:lang="fr">Bulgarie</country>
<wicri:regionArea>Department of Psychiatry, New Bulgarian University, Sofia</wicri:regionArea>
<placeName>
<settlement type="city">Sofia</settlement>
<region nuts="2">Sofia-ville (oblast)</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Kessler, Ronald C" sort="Kessler, Ronald C" uniqKey="Kessler R" first="Ronald C." last="Kessler">Ronald C. Kessler</name>
<affiliation wicri:level="2">
<nlm:aff id="A4">Department of Health Care Policy, Harvard Medical School, Boston, MA USA</nlm:aff>
<country>États-Unis</country>
<placeName>
<region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Department of Health Care Policy, Harvard Medical School, Boston</wicri:cityArea>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Biological psychiatry</title>
<idno type="ISSN">0006-3223</idno>
<idno type="eISSN">1873-2402</idno>
<imprint>
<date when="2010">2010</date>
</imprint>
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<textClass></textClass>
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</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<sec id="S1">
<title>Background</title>
<p id="P1">Controversy exists about the utility of DSM-IV post-traumatic stress disorder (PTSD) Criterion A2: that exposure to a potentially traumatic experience (PTE; PTSD Criterion A1) is accompanied by intense fear, helplessness, or horror.</p>
</sec>
<sec sec-type="methods" id="S2">
<title>Methods</title>
<p id="P2">Lifetime DSM-IV PTSD was assessed with the Composite International Diagnostic Interview in community surveys of 52,826 respondents across 21 countries in the World Mental Health Surveys.</p>
</sec>
<sec id="S3">
<title>Results</title>
<p id="P3">37.6% of 28,490 representative PTEs reported by respondents met Criterion A2, a proportion higher than the proportions meeting other criteria (B-F; 5.4-9.6%). Conditional prevalence of meeting all other criteria for a diagnosis of PTSD given a PTE was significantly higher in the presence (9.7%) than absence (0.1%) of A2. However, as only 1.4% of respondents who met all other criteria failed A2, the estimated prevalence of PTSD increased only slightly (from 3.64% to 3.69%) when A2 was not required for diagnosis. PTSD with or without Criterion A2 did not differ in persistence or predicted consequences (subsequent suicidal ideation or secondary disorders) depending on presence-absence of A2. Furthermore, as A2 was by far the most commonly reported symptom of PTSD, initial assessment of A2 would be much less efficient than screening other criteria in quickly ruling out a large proportion of non-cases.</p>
</sec>
<sec id="S4">
<title>Conclusion</title>
<p id="P4">Removal of A2 from the DSM-IV criterion set would reduce the complexity of diagnosing PTSD while not substantially increasing the number of people who qualify for diagnosis. A2 should consequently be reconceptualized as a risk factor for PTSD rather than as a diagnostic requirement.</p>
</sec>
</div>
</front>
</TEI>
</record>

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