AustralieFrV1, Main, Merge, bibRecord, 007126

Child Health, Developmental Plasticity, and Epigenetic Programming

Identifieur interne : 007126 ( Main/Merge ); précédent : 007125; suivant : 007127

Child Health, Developmental Plasticity, and Epigenetic Programming

Auteurs : Z. Hochberg [Israël] ; R. Feil [France] ; M. Constancia [Royaume-Uni] ; M. Fraga [Espagne] ; C. Junien [France] ; J.-C. Carel [France] ; P. Boileau [France] ; Y. Le Bouc [France] ; C. L. Deal [Canada] ; K. Lillycrop [Royaume-Uni] ; R. Scharfmann [France] ; A. Sheppard [Nouvelle-Zélande] ; M. Skinner [États-Unis] ; M. Szyf [Canada] ; R. A. Waterland [États-Unis] ; D. J. Waxman [États-Unis] ; E. Whitelaw [Australie] ; K. Ong [Royaume-Uni] ; K. Albertsson-Wikland [Suède]

Source :

Endocrine reviews [ 0163-769X ] ; 2011.

RBID : Pascal:11-0342900

Descripteurs français

Pascal (Inist)
- Développement, Plasticité, Article synthèse, Epigénétique, Enfant.
Wicri :
- topic : Enfant.

English descriptors

KwdEn :
- Child, Development, Epigenetics, Plasticity, Review.

Abstract

Plasticity in developmental programming has evolved in order to provide the best chances of survival and reproductive success to the organism under changing environments. Environmental conditions that are experienced in early life can profoundly influence human biology and long-term health. Developmental origins of health and disease and life-history transitions are purported to use placental, nutritional, and endocrine cues for setting long-term biological, mental, and behavioral strategies in response to local ecological and/or social conditions. The window of developmental plasticity extends from preconception to early childhood and involves epigenetic responses to environmental changes, which exert their effects during life-history phase transitions. These epigenetic responses influence development, cell- and tissue-specific gene expression, and sexual dimorphism, and, in exceptional cases, could be transmitted transgenerationally. Translational epigenetic research in child health is a reiterative process that ranges from research inthe basic sciences, preclinical research, and pediatric clinical research. Identifying the epigenetic consequences of fetal programming creates potential applications in clinical practice: the development of epigenetic biomarkers for early diagnosis of disease, the ability to identify susceptible individuals at risk for adult diseases, and the development of novel preventive and curative measures that are based on diet and/or novel epigenetic drugs.

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Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Child Health, Developmental Plasticity, and Epigenetic Programming</title>
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</affiliation>
</author>
<author><name sortKey="Szyf, M" sort="Szyf, M" uniqKey="Szyf M" first="M." last="Szyf">M. Szyf</name>
<affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Department of Pharmacology and Therapeutics McGill University</s1>
<s2>Montreal, Quebec, H2X 3P8</s2>
<s3>CAN</s3>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Department of Pharmacology and Therapeutics McGill University</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Waterland, R A" sort="Waterland, R A" uniqKey="Waterland R" first="R. A." last="Waterland">R. A. Waterland</name>
<affiliation wicri:level="4"><inist:fA14 i1="15"><s1>U.S. Department of Agriculture Children's Nutrition Research Center Departments of Pediatrics and Molecular and Human Genetics, Baylor College of Medicine</s1>
<s2>Houston, Texas 77030</s2>
<s3>USA</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><settlement type="city">Houston</settlement>
<region type="state">Texas</region>
</placeName>
<orgName type="university">Baylor College of Medicine</orgName>
</affiliation>
</author>
<author><name sortKey="Waxman, D J" sort="Waxman, D J" uniqKey="Waxman D" first="D. J." last="Waxman">D. J. Waxman</name>
<affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Department of Biology Boston University</s1>
<s2>Boston, Massachusetts 02215</s2>
<s3>USA</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Department of Biology Boston University</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Whitelaw, E" sort="Whitelaw, E" uniqKey="Whitelaw E" first="E." last="Whitelaw">E. Whitelaw</name>
<affiliation wicri:level="1"><inist:fA14 i1="17"><s1>Queensland Institute of Medical Research</s1>
<s2>Brisbane, Queensland 4006</s2>
<s3>AUS</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Queensland Institute of Medical Research</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ong, K" sort="Ong, K" uniqKey="Ong K" first="K." last="Ong">K. Ong</name>
<affiliation wicri:level="1"><inist:fA14 i1="18"><s1>Medical Research Council Epidemiology Unit Institute of Metabolic Science, Addenbrooke's Hospital</s1>
<s2>Cambridge CB2 0QQ</s2>
<s3>GBR</s3>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<wicri:noRegion>Cambridge CB2 0QQ</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Albertsson Wikland, K" sort="Albertsson Wikland, K" uniqKey="Albertsson Wikland K" first="K." last="Albertsson-Wikland">K. Albertsson-Wikland</name>
<affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Göteborg Pediatric Research Centre Sahlgrenska Academy at Goteborg University</s1>
<s2>413 45 Goteborg</s2>
<s3>SWE</s3>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>Suède</country>
<wicri:noRegion>Göteborg Pediatric Research Centre Sahlgrenska Academy at Goteborg University</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Endocrine reviews</title>
<title level="j" type="abbreviated">Endocr. rev.</title>
<idno type="ISSN">0163-769X</idno>
<imprint><date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Endocrine reviews</title>
<title level="j" type="abbreviated">Endocr. rev.</title>
<idno type="ISSN">0163-769X</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Child</term>
<term>Development</term>
<term>Epigenetics</term>
<term>Plasticity</term>
<term>Review</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Développement</term>
<term>Plasticité</term>
<term>Article synthèse</term>
<term>Epigénétique</term>
<term>Enfant</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Enfant</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Plasticity in developmental programming has evolved in order to provide the best chances of survival and reproductive success to the organism under changing environments. Environmental conditions that are experienced in early life can profoundly influence human biology and long-term health. Developmental origins of health and disease and life-history transitions are purported to use placental, nutritional, and endocrine cues for setting long-term biological, mental, and behavioral strategies in response to local ecological and/or social conditions. The window of developmental plasticity extends from preconception to early childhood and involves epigenetic responses to environmental changes, which exert their effects during life-history phase transitions. These epigenetic responses influence development, cell- and tissue-specific gene expression, and sexual dimorphism, and, in exceptional cases, could be transmitted transgenerationally. Translational epigenetic research in child health is a reiterative process that ranges from research inthe basic sciences, preclinical research, and pediatric clinical research. Identifying the epigenetic consequences of fetal programming creates potential applications in clinical practice: the development of epigenetic biomarkers for early diagnosis of disease, the ability to identify susceptible individuals at risk for adult diseases, and the development of novel preventive and curative measures that are based on diet and/or novel epigenetic drugs.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>Canada</li>
<li>Espagne</li>
<li>France</li>
<li>Israël</li>
<li>Nouvelle-Zélande</li>
<li>Royaume-Uni</li>
<li>Suède</li>
<li>États-Unis</li>
</country>
<region><li>Angleterre</li>
<li>Angleterre de l'Est</li>
<li>Languedoc-Roussillon</li>
<li>Occitanie (région administrative)</li>
<li>Principauté des Asturies</li>
<li>Texas</li>
<li>Île-de-France</li>
</region>
<settlement><li>Cambridge</li>
<li>Houston</li>
<li>Montpellier</li>
<li>Paris</li>
</settlement>
<orgName><li>Baylor College of Medicine</li>
<li>Université de Cambridge</li>
</orgName>
</list>
<tree><country name="Israël"><noRegion><name sortKey="Hochberg, Z" sort="Hochberg, Z" uniqKey="Hochberg Z" first="Z." last="Hochberg">Z. Hochberg</name>
</noRegion>
</country>
<country name="France"><region name="Occitanie (région administrative)"><name sortKey="Feil, R" sort="Feil, R" uniqKey="Feil R" first="R." last="Feil">R. Feil</name>
</region>
<name sortKey="Boileau, P" sort="Boileau, P" uniqKey="Boileau P" first="P." last="Boileau">P. Boileau</name>
<name sortKey="Carel, J C" sort="Carel, J C" uniqKey="Carel J" first="J.-C." last="Carel">J.-C. Carel</name>
<name sortKey="Junien, C" sort="Junien, C" uniqKey="Junien C" first="C." last="Junien">C. Junien</name>
<name sortKey="Le Bouc, Y" sort="Le Bouc, Y" uniqKey="Le Bouc Y" first="Y." last="Le Bouc">Y. Le Bouc</name>
<name sortKey="Scharfmann, R" sort="Scharfmann, R" uniqKey="Scharfmann R" first="R." last="Scharfmann">R. Scharfmann</name>
</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Constancia, M" sort="Constancia, M" uniqKey="Constancia M" first="M." last="Constancia">M. Constancia</name>
</region>
<name sortKey="Lillycrop, K" sort="Lillycrop, K" uniqKey="Lillycrop K" first="K." last="Lillycrop">K. Lillycrop</name>
<name sortKey="Ong, K" sort="Ong, K" uniqKey="Ong K" first="K." last="Ong">K. Ong</name>
</country>
<country name="Espagne"><region name="Principauté des Asturies"><name sortKey="Fraga, M" sort="Fraga, M" uniqKey="Fraga M" first="M." last="Fraga">M. Fraga</name>
</region>
</country>
<country name="Canada"><noRegion><name sortKey="Deal, C L" sort="Deal, C L" uniqKey="Deal C" first="C. L." last="Deal">C. L. Deal</name>
</noRegion>
<name sortKey="Szyf, M" sort="Szyf, M" uniqKey="Szyf M" first="M." last="Szyf">M. Szyf</name>
</country>
<country name="Nouvelle-Zélande"><noRegion><name sortKey="Sheppard, A" sort="Sheppard, A" uniqKey="Sheppard A" first="A." last="Sheppard">A. Sheppard</name>
</noRegion>
</country>
<country name="États-Unis"><noRegion><name sortKey="Skinner, M" sort="Skinner, M" uniqKey="Skinner M" first="M." last="Skinner">M. Skinner</name>
</noRegion>
<name sortKey="Waterland, R A" sort="Waterland, R A" uniqKey="Waterland R" first="R. A." last="Waterland">R. A. Waterland</name>
<name sortKey="Waxman, D J" sort="Waxman, D J" uniqKey="Waxman D" first="D. J." last="Waxman">D. J. Waxman</name>
</country>
<country name="Australie"><noRegion><name sortKey="Whitelaw, E" sort="Whitelaw, E" uniqKey="Whitelaw E" first="E." last="Whitelaw">E. Whitelaw</name>
</noRegion>
</country>
<country name="Suède"><noRegion><name sortKey="Albertsson Wikland, K" sort="Albertsson Wikland, K" uniqKey="Albertsson Wikland K" first="K." last="Albertsson-Wikland">K. Albertsson-Wikland</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

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	Serveur d'exploration sur les relations entre la France et l'Australie
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Serveur d'exploration sur les relations entre la France et l'Australie

Child Health, Developmental Plasticity, and Epigenetic Programming

Child Health, Developmental Plasticity, and Epigenetic Programming

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