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Guidelines for Reporting Case Studies on Extracorporeal Treatments in Poisonings: Methodology

Identifieur interne : 003E45 ( Main/Merge ); précédent : 003E44; suivant : 003E46

Guidelines for Reporting Case Studies on Extracorporeal Treatments in Poisonings: Methodology

Auteurs : Valéry Lavergne [Canada] ; Georges Ouellet [Canada] ; Josée Bouchard [Canada] ; Tais Galvao [Brésil] ; Jan T. Kielstein [Allemagne] ; Darren M. Roberts [Australie, Royaume-Uni] ; Salmaan Kanji [Canada] ; James B. Mowry ; Diane P. Calello ; Robert S. Hoffman [États-Unis] ; Sophie Gosselin [Canada] ; Thomas D. Nolin [États-Unis] ; David S. Goldfarb [États-Unis] ; Emmanuel A. Burdmann [Brésil] ; Paul I. Dargan [Royaume-Uni] ; Brian Scott Decker [États-Unis] ; Lotte C. Hoegberg [Danemark] ; Robert Maclaren ; Bruno Megarbane [France] ; Kevin M. Sowinski ; Christopher Yates [Espagne] ; Robert Mactier [Royaume-Uni] ; Timothy Wiegand ; Marc Ghannoum [Canada]

Source :

RBID : ISTEX:E458AE6A5EF13B5513BEC2AE5872ED6637B04E90

Abstract

A literature review performed by the EXtracorporeal TReatments In Poisoning (EXTRIP) workgroup highlighted deficiencies in the existing literature, especially the reporting of case studies. Although general reporting guidelines exist for case studies, there are none in the specific field of extracorporeal treatments in toxicology. Our goal was to construct and propose a checklist that systematically outlines the minimum essential items to be reported in a case study of poisoned patients undergoing extracorporeal treatments. Through a modified two‐round Delphi technique, panelists (mostly chosen from the EXTRIP workgroup) were asked to vote on the pertinence of a set of items to identify those considered minimally essential for reporting complete and accurate case reports. Furthermore, independent raters validated the clarity of each selected items between each round of voting. All case reports containing data on extracorporeal treatments in poisoning published in Medline in 2011 were reviewed during the external validation rounds. Twenty‐one panelists (20 from the EXTRIP workgroup and an invited expert on pharmacology reporting guidelines) participated in the modified Delphi technique. This group included journal editors and experts in nephrology, clinical toxicology, critical care medicine, emergency medicine, and clinical pharmacology. Three independent raters participated in the validation rounds. Panelists voted on a total of 144 items in the first round and 137 items in the second round, with response rates of 96.3% and 98.3%, respectively. Twenty case reports were evaluated at each validation round and the independent raters' response rate was 99.6% and 98.8% per validation round. The final checklist consists of 114 items considered essential for case study reporting. This methodology of alternate voting and external validation rounds was useful in developing the first reporting guideline for case studies in the field of extracorporeal treatments in poisoning. We believe that this guideline will improve the completeness and transparency of published case reports and that the systematic aggregation of information from case reports may provide early signals of effectiveness and/or harm, thereby improving healthcare decision‐making.

Url:
DOI: 10.1111/sdi.12251

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ISTEX:E458AE6A5EF13B5513BEC2AE5872ED6637B04E90

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<div type="abstract">A literature review performed by the EXtracorporeal TReatments In Poisoning (EXTRIP) workgroup highlighted deficiencies in the existing literature, especially the reporting of case studies. Although general reporting guidelines exist for case studies, there are none in the specific field of extracorporeal treatments in toxicology. Our goal was to construct and propose a checklist that systematically outlines the minimum essential items to be reported in a case study of poisoned patients undergoing extracorporeal treatments. Through a modified two‐round Delphi technique, panelists (mostly chosen from the EXTRIP workgroup) were asked to vote on the pertinence of a set of items to identify those considered minimally essential for reporting complete and accurate case reports. Furthermore, independent raters validated the clarity of each selected items between each round of voting. All case reports containing data on extracorporeal treatments in poisoning published in Medline in 2011 were reviewed during the external validation rounds. Twenty‐one panelists (20 from the EXTRIP workgroup and an invited expert on pharmacology reporting guidelines) participated in the modified Delphi technique. This group included journal editors and experts in nephrology, clinical toxicology, critical care medicine, emergency medicine, and clinical pharmacology. Three independent raters participated in the validation rounds. Panelists voted on a total of 144 items in the first round and 137 items in the second round, with response rates of 96.3% and 98.3%, respectively. Twenty case reports were evaluated at each validation round and the independent raters' response rate was 99.6% and 98.8% per validation round. The final checklist consists of 114 items considered essential for case study reporting. This methodology of alternate voting and external validation rounds was useful in developing the first reporting guideline for case studies in the field of extracorporeal treatments in poisoning. We believe that this guideline will improve the completeness and transparency of published case reports and that the systematic aggregation of information from case reports may provide early signals of effectiveness and/or harm, thereby improving healthcare decision‐making.</div>
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<author>
<name sortKey="Kielstein, Jan T" sort="Kielstein, Jan T" uniqKey="Kielstein J" first="Jan T." last="Kielstein">Jan T. Kielstein</name>
</author>
<author>
<name sortKey="Roberts, Darren M" sort="Roberts, Darren M" uniqKey="Roberts D" first="Darren M." last="Roberts">Darren M. Roberts</name>
</author>
<author>
<name sortKey="Kanji, Salmaan" sort="Kanji, Salmaan" uniqKey="Kanji S" first="Salmaan" last="Kanji">Salmaan Kanji</name>
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<author>
<name sortKey="Mowry, James B" sort="Mowry, James B" uniqKey="Mowry J" first="James B." last="Mowry">James B. Mowry</name>
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<author>
<name sortKey="Calello, Diane P" sort="Calello, Diane P" uniqKey="Calello D" first="Diane P." last="Calello">Diane P. Calello</name>
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<author>
<name sortKey="Hoffman, Robert S" sort="Hoffman, Robert S" uniqKey="Hoffman R" first="Robert S." last="Hoffman">Robert S. Hoffman</name>
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<author>
<name sortKey="Gosselin, Sophie" sort="Gosselin, Sophie" uniqKey="Gosselin S" first="Sophie" last="Gosselin">Sophie Gosselin</name>
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<author>
<name sortKey="Nolin, Thomas D" sort="Nolin, Thomas D" uniqKey="Nolin T" first="Thomas D." last="Nolin">Thomas D. Nolin</name>
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<author>
<name sortKey="Goldfarb, David S" sort="Goldfarb, David S" uniqKey="Goldfarb D" first="David S." last="Goldfarb">David S. Goldfarb</name>
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<author>
<name sortKey="Burdmann, Emmanuel A" sort="Burdmann, Emmanuel A" uniqKey="Burdmann E" first="Emmanuel A." last="Burdmann">Emmanuel A. Burdmann</name>
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<author>
<name sortKey="Dargan, Paul I" sort="Dargan, Paul I" uniqKey="Dargan P" first="Paul I." last="Dargan">Paul I. Dargan</name>
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<author>
<name sortKey="Decker, Brian Scott" sort="Decker, Brian Scott" uniqKey="Decker B" first="Brian Scott" last="Decker">Brian Scott Decker</name>
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<author>
<name sortKey="Hoegberg, Lotte C" sort="Hoegberg, Lotte C" uniqKey="Hoegberg L" first="Lotte C." last="Hoegberg">Lotte C. Hoegberg</name>
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<author>
<name sortKey="Maclaren, Robert" sort="Maclaren, Robert" uniqKey="Maclaren R" first="Robert" last="Maclaren">Robert Maclaren</name>
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<author>
<name sortKey="Megarbane, Bruno" sort="Megarbane, Bruno" uniqKey="Megarbane B" first="Bruno" last="Megarbane">Bruno Megarbane</name>
</author>
<author>
<name sortKey="Sowinski, Kevin M" sort="Sowinski, Kevin M" uniqKey="Sowinski K" first="Kevin M." last="Sowinski">Kevin M. Sowinski</name>
</author>
<author>
<name sortKey="Yates, Christopher" sort="Yates, Christopher" uniqKey="Yates C" first="Christopher" last="Yates">Christopher Yates</name>
</author>
<author>
<name sortKey="Mactier, Robert" sort="Mactier, Robert" uniqKey="Mactier R" first="Robert" last="Mactier">Robert Mactier</name>
</author>
<author>
<name sortKey="Wiegand, Timothy" sort="Wiegand, Timothy" uniqKey="Wiegand T" first="Timothy" last="Wiegand">Timothy Wiegand</name>
</author>
<author>
<name sortKey="Ghannoum, Marc" sort="Ghannoum, Marc" uniqKey="Ghannoum M" first="Marc" last="Ghannoum">Marc Ghannoum</name>
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<affiliation></affiliation>
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<name sortKey="Ouellet, Georges" sort="Ouellet, Georges" uniqKey="Ouellet G" first="Georges" last="Ouellet">Georges Ouellet</name>
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<wicri:regionArea>Division of Nephrology, Hôpital Maisonneuve‐Rosemont, University of Montreal, Quebec, Montreal</wicri:regionArea>
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</author>
<author>
<name sortKey="Bouchard, Josee" sort="Bouchard, Josee" uniqKey="Bouchard J" first="Josée" last="Bouchard">Josée Bouchard</name>
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</affiliation>
</author>
<author>
<name sortKey="Kanji, Salmaan" sort="Kanji, Salmaan" uniqKey="Kanji S" first="Salmaan" last="Kanji">Salmaan Kanji</name>
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<wicri:noCountry code="subField">Indianapolis</wicri:noCountry>
</affiliation>
</author>
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<name sortKey="Calello, Diane P" sort="Calello, Diane P" uniqKey="Calello D" first="Diane P." last="Calello">Diane P. Calello</name>
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<wicri:noCountry code="subField">Morristown</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Hoffman, Robert S" sort="Hoffman, Robert S" uniqKey="Hoffman R" first="Robert S." last="Hoffman">Robert S. Hoffman</name>
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<settlement type="city">New York</settlement>
<region type="state">État de New York</region>
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</affiliation>
</author>
<author>
<name sortKey="Gosselin, Sophie" sort="Gosselin, Sophie" uniqKey="Gosselin S" first="Sophie" last="Gosselin">Sophie Gosselin</name>
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<settlement type="city">Montréal</settlement>
<region type="state">Québec</region>
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<settlement type="city">Pittsburgh</settlement>
<region type="state">Pennsylvanie</region>
</placeName>
<wicri:orgArea>Department of Pharmacy and Therapeutics, Center for Clinical Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pennsylvania</wicri:orgArea>
</affiliation>
</author>
<author>
<name sortKey="Goldfarb, David S" sort="Goldfarb, David S" uniqKey="Goldfarb D" first="David S." last="Goldfarb">David S. Goldfarb</name>
<affiliation wicri:level="3">
<country>États-Unis</country>
<placeName>
<settlement type="city">New York</settlement>
<region type="state">État de New York</region>
</placeName>
<wicri:orgArea>Nephrology, NYU Langone Medical Center, NYU School of Medicine, New York</wicri:orgArea>
</affiliation>
</author>
<author>
<name sortKey="Burdmann, Emmanuel A" sort="Burdmann, Emmanuel A" uniqKey="Burdmann E" first="Emmanuel A." last="Burdmann">Emmanuel A. Burdmann</name>
<affiliation wicri:level="3">
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Division of Nephrology, University of Sao Paulo Medical School, Sao Paulo</wicri:regionArea>
<placeName>
<settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Dargan, Paul I" sort="Dargan, Paul I" uniqKey="Dargan P" first="Paul I." last="Dargan">Paul I. Dargan</name>
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<settlement type="city">Londres</settlement>
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</placeName>
</affiliation>
</author>
<author>
<name sortKey="Decker, Brian Scott" sort="Decker, Brian Scott" uniqKey="Decker B" first="Brian Scott" last="Decker">Brian Scott Decker</name>
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<region type="state">Indiana</region>
</placeName>
<wicri:cityArea>Division of Nephrology, Indiana University School of Medicine, Indianapolis</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Hoegberg, Lotte C" sort="Hoegberg, Lotte C" uniqKey="Hoegberg L" first="Lotte C." last="Hoegberg">Lotte C. Hoegberg</name>
<affiliation wicri:level="3">
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Danish Poisons Information Centre, Anaesthesiology Bispebjerg University Hospital, Copenhagen</wicri:regionArea>
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<settlement type="city">Copenhague</settlement>
<region type="région" nuts="2">Hovedstaden</region>
</placeName>
</affiliation>
</author>
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<name sortKey="Maclaren, Robert" sort="Maclaren, Robert" uniqKey="Maclaren R" first="Robert" last="Maclaren">Robert Maclaren</name>
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<wicri:noCountry code="subField">Aurora</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Megarbane, Bruno" sort="Megarbane, Bruno" uniqKey="Megarbane B" first="Bruno" last="Megarbane">Bruno Megarbane</name>
<affiliation wicri:level="3">
<country xml:lang="fr">France</country>
<wicri:regionArea>Hôpital Lariboisière, Réanimation Médicale et Toxicologique, INSERM U1144, Université Paris‐Diderot, Paris</wicri:regionArea>
<placeName>
<region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Sowinski, Kevin M" sort="Sowinski, Kevin M" uniqKey="Sowinski K" first="Kevin M." last="Sowinski">Kevin M. Sowinski</name>
<affiliation>
<wicri:noCountry code="subField">Lafayette/Indianapolis</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Yates, Christopher" sort="Yates, Christopher" uniqKey="Yates C" first="Christopher" last="Yates">Christopher Yates</name>
<affiliation wicri:level="1">
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Emergency Department and Clinical Toxicology Unit, Hospital Universitari Son Espases, Mallorca</wicri:regionArea>
<wicri:noRegion>Mallorca</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Mactier, Robert" sort="Mactier, Robert" uniqKey="Mactier R" first="Robert" last="Mactier">Robert Mactier</name>
<affiliation wicri:level="1">
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Greater Glasgow & Clyde, Renal Services, Glasgow</wicri:regionArea>
<wicri:noRegion>Glasgow</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Wiegand, Timothy" sort="Wiegand, Timothy" uniqKey="Wiegand T" first="Timothy" last="Wiegand">Timothy Wiegand</name>
<affiliation>
<wicri:noCountry code="subField">Rochester</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Ghannoum, Marc" sort="Ghannoum, Marc" uniqKey="Ghannoum M" first="Marc" last="Ghannoum">Marc Ghannoum</name>
<affiliation wicri:level="1">
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Nephrology, Verdun Hospital, University of Montreal, Quebec, Verdun</wicri:regionArea>
<wicri:noRegion>Verdun</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series>
<title level="j" type="main">Seminars in Dialysis</title>
<title level="j" type="alt">SEMINARS IN DIALYSIS</title>
<idno type="ISSN">0894-0959</idno>
<idno type="eISSN">1525-139X</idno>
<imprint>
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<biblScope unit="page-count">8</biblScope>
<date type="published" when="2014-07">2014-07</date>
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<front>
<div type="abstract">A literature review performed by the EXtracorporeal TReatments In Poisoning (EXTRIP) workgroup highlighted deficiencies in the existing literature, especially the reporting of case studies. Although general reporting guidelines exist for case studies, there are none in the specific field of extracorporeal treatments in toxicology. Our goal was to construct and propose a checklist that systematically outlines the minimum essential items to be reported in a case study of poisoned patients undergoing extracorporeal treatments. Through a modified two‐round Delphi technique, panelists (mostly chosen from the EXTRIP workgroup) were asked to vote on the pertinence of a set of items to identify those considered minimally essential for reporting complete and accurate case reports. Furthermore, independent raters validated the clarity of each selected items between each round of voting. All case reports containing data on extracorporeal treatments in poisoning published in Medline in 2011 were reviewed during the external validation rounds. Twenty‐one panelists (20 from the EXTRIP workgroup and an invited expert on pharmacology reporting guidelines) participated in the modified Delphi technique. This group included journal editors and experts in nephrology, clinical toxicology, critical care medicine, emergency medicine, and clinical pharmacology. Three independent raters participated in the validation rounds. Panelists voted on a total of 144 items in the first round and 137 items in the second round, with response rates of 96.3% and 98.3%, respectively. Twenty case reports were evaluated at each validation round and the independent raters' response rate was 99.6% and 98.8% per validation round. The final checklist consists of 114 items considered essential for case study reporting. This methodology of alternate voting and external validation rounds was useful in developing the first reporting guideline for case studies in the field of extracorporeal treatments in poisoning. We believe that this guideline will improve the completeness and transparency of published case reports and that the systematic aggregation of information from case reports may provide early signals of effectiveness and/or harm, thereby improving healthcare decision‐making.</div>
</front>
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</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Montreal, Quebec</wicri:regionArea>
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</affiliation>
</author>
<author>
<name sortKey="Ouellet, Georges" sort="Ouellet, Georges" uniqKey="Ouellet G" first="Georges" last="Ouellet">Georges Ouellet</name>
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</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Montreal, Quebec</wicri:regionArea>
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</affiliation>
</author>
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<name sortKey="Bouchard, Josee" sort="Bouchard, Josee" uniqKey="Bouchard J" first="Josée" last="Bouchard">Josée Bouchard</name>
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</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Montreal, Quebec</wicri:regionArea>
<wicri:noRegion>Quebec</wicri:noRegion>
</affiliation>
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<name sortKey="Galvao, Tais" sort="Galvao, Tais" uniqKey="Galvao T" first="Tais" last="Galvao">Tais Galvao</name>
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<nlm:aff id="au4">
<institution>Getulio Vargas University Hospital, Federal University of Amazonas</institution>
<addr-line>Manaus, Amazonas, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Manaus, Amazonas</wicri:regionArea>
<wicri:noRegion>Amazonas</wicri:noRegion>
</affiliation>
</author>
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<name sortKey="Kielstein, Jan T" sort="Kielstein, Jan T" uniqKey="Kielstein J" first="Jan T" last="Kielstein">Jan T. Kielstein</name>
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<nlm:aff id="au5">
<institution>Department of Nephrology and Hypertension, Hannover Medical School</institution>
<addr-line>Hannover, Germany</addr-line>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Hannover</wicri:regionArea>
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<name sortKey="Roberts, Darren M" sort="Roberts, Darren M" uniqKey="Roberts D" first="Darren M" last="Roberts">Darren M. Roberts</name>
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<nlm:aff id="au6">
<institution>School of Medicine, University of Queensland</institution>
<addr-line>Brisbane, Queensland, Australia</addr-line>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Brisbane, Queensland</wicri:regionArea>
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<institution>Department of Renal Medicine, Addenbrooke's Hospital</institution>
<addr-line>Cambridge, UK</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Cambridge</wicri:regionArea>
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<name sortKey="Kanji, Salmaan" sort="Kanji, Salmaan" uniqKey="Kanji S" first="Salmaan" last="Kanji">Salmaan Kanji</name>
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<nlm:aff id="au8">
<institution>The Ottawa Hospital Research Institute, The Ottawa Hospital</institution>
<addr-line>Ottawa, Ontario, Canada</addr-line>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Ottawa, Ontario</wicri:regionArea>
<wicri:noRegion>Ontario</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Mowry, James B" sort="Mowry, James B" uniqKey="Mowry J" first="James B" last="Mowry">James B. Mowry</name>
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<nlm:aff id="au9">
<institution>Indiana University Health, Indiana Poison Center</institution>
<addr-line>Indianapolis, Indiana</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
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<region type="state">Indiana</region>
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<wicri:cityArea>Indianapolis</wicri:cityArea>
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<name sortKey="Calello, Diane P" sort="Calello, Diane P" uniqKey="Calello D" first="Diane P" last="Calello">Diane P. Calello</name>
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<nlm:aff id="au10">
<institution>Division of Medical Toxicology, Department of Emergency Medicine, Morristown Medical Center</institution>
<addr-line>Morristown, New Jersey</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">New Jersey</region>
</placeName>
<wicri:cityArea>Morristown</wicri:cityArea>
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</author>
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<nlm:aff id="au11">
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<institution>Department of Emergency Medicine, Medical Toxicology Service, McGill University Health Centre, McGill University</institution>
<addr-line>Montreal, Quebec, Canada</addr-line>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Montreal, Quebec</wicri:regionArea>
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<author>
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<nlm:aff id="au13">
<institution>Department of Pharmacy and Therapeutics, Center for Clinical Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy</institution>
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</nlm:aff>
<country xml:lang="fr">États-Unis</country>
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<region type="state">Pennsylvanie</region>
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</author>
<author>
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<nlm:aff id="au14">
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<addr-line>New York City, New York</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">État de New York</region>
</placeName>
<wicri:cityArea>New York City</wicri:cityArea>
</affiliation>
</author>
<author>
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<affiliation wicri:level="1">
<nlm:aff id="au15">
<institution>Division of Nephrology, University of Sao Paulo Medical School</institution>
<addr-line>Sao Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Sao Paulo</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Dargan, Paul I" sort="Dargan, Paul I" uniqKey="Dargan P" first="Paul I" last="Dargan">Paul I. Dargan</name>
<affiliation wicri:level="1">
<nlm:aff id="au16">
<institution>Guy's and St Thomas' NHS Foundation Trust</institution>
<addr-line>London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>London</wicri:regionArea>
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</author>
<author>
<name sortKey="Decker, Brian Scott" sort="Decker, Brian Scott" uniqKey="Decker B" first="Brian Scott" last="Decker">Brian Scott Decker</name>
<affiliation wicri:level="2">
<nlm:aff id="au17">
<institution>Division of Nephrology, Indiana University School of Medicine</institution>
<addr-line>Indianapolis, Indiana</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Indiana</region>
</placeName>
<wicri:cityArea>Indianapolis</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Hoegberg, Lotte C" sort="Hoegberg, Lotte C" uniqKey="Hoegberg L" first="Lotte C" last="Hoegberg">Lotte C. Hoegberg</name>
<affiliation wicri:level="1">
<nlm:aff id="au18">
<institution>Danish Poisons Information Centre, Anaesthesiology Bispebjerg University Hospital</institution>
<addr-line>Copenhagen, Denmark</addr-line>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Copenhagen</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Maclaren, Robert" sort="Maclaren, Robert" uniqKey="Maclaren R" first="Robert" last="Maclaren">Robert Maclaren</name>
<affiliation wicri:level="2">
<nlm:aff id="au19">
<institution>University of Colorado School of Pharmacy, Clinical Pharmacy</institution>
<addr-line>Aurora, Colorado</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Colorado</region>
</placeName>
<wicri:cityArea>Aurora</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Megarbane, Bruno" sort="Megarbane, Bruno" uniqKey="Megarbane B" first="Bruno" last="Megarbane">Bruno Megarbane</name>
<affiliation wicri:level="1">
<nlm:aff id="au20">
<institution>Hôpital Lariboisière, Réanimation Médicale et Toxicologique, INSERM U1144, Université Paris-Diderot</institution>
<addr-line>Paris, France</addr-line>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Paris</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Sowinski, Kevin M" sort="Sowinski, Kevin M" uniqKey="Sowinski K" first="Kevin M" last="Sowinski">Kevin M. Sowinski</name>
<affiliation wicri:level="2">
<nlm:aff id="au21">
<institution>Department of Pharmacy Practice, College of Pharmacy, Purdue University</institution>
<addr-line>West Lafayette/Indianapolis, Indiana</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Indiana</region>
</placeName>
<wicri:cityArea>West Lafayette/Indianapolis</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Yates, Christopher" sort="Yates, Christopher" uniqKey="Yates C" first="Christopher" last="Yates">Christopher Yates</name>
<affiliation wicri:level="1">
<nlm:aff id="au22">
<institution>Emergency Department and Clinical Toxicology Unit, Hospital Universitari Son Espases</institution>
<addr-line>Mallorca, Spain</addr-line>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Mallorca</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Mactier, Robert" sort="Mactier, Robert" uniqKey="Mactier R" first="Robert" last="Mactier">Robert Mactier</name>
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<nlm:aff id="au23">
<institution>Greater Glasgow & Clyde, Renal Services</institution>
<addr-line>Glasgow, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Glasgow</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Wiegand, Timothy" sort="Wiegand, Timothy" uniqKey="Wiegand T" first="Timothy" last="Wiegand">Timothy Wiegand</name>
<affiliation wicri:level="2">
<nlm:aff id="au24">
<institution>The University of Rochester Medical Center and Strong Memorial Hospital</institution>
<addr-line>Rochester, New York</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Rochester</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Ghannoum, Marc" sort="Ghannoum, Marc" uniqKey="Ghannoum M" first="Marc" last="Ghannoum">Marc Ghannoum</name>
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<nlm:aff id="au26">
<institution>Department of Nephrology, Verdun Hospital, University of Montreal</institution>
<addr-line>Verdun, Quebec, Canada</addr-line>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Verdun, Quebec</wicri:regionArea>
<wicri:noRegion>Quebec</wicri:noRegion>
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<title xml:lang="en" level="a" type="main">Guidelines for Reporting Case Studies on Extracorporeal Treatments in Poisonings: Methodology</title>
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<name sortKey="Lavergne, Valery" sort="Lavergne, Valery" uniqKey="Lavergne V" first="Valéry" last="Lavergne">Valéry Lavergne</name>
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<nlm:aff id="au1">
<institution>Department of Medical Biology, Hôpital du Sacré-Coeur de Montréal, University of Montreal</institution>
<addr-line>Montreal, Quebec, Canada</addr-line>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Montreal, Quebec</wicri:regionArea>
<wicri:noRegion>Quebec</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Ouellet, Georges" sort="Ouellet, Georges" uniqKey="Ouellet G" first="Georges" last="Ouellet">Georges Ouellet</name>
<affiliation wicri:level="1">
<nlm:aff id="au2">
<institution>Division of Nephrology, Hôpital Maisonneuve-Rosemont, University of Montreal</institution>
<addr-line>Montreal, Quebec, Canada</addr-line>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Montreal, Quebec</wicri:regionArea>
<wicri:noRegion>Quebec</wicri:noRegion>
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</author>
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<name sortKey="Bouchard, Josee" sort="Bouchard, Josee" uniqKey="Bouchard J" first="Josée" last="Bouchard">Josée Bouchard</name>
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<nlm:aff id="au3">
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<addr-line>Montreal, Quebec, Canada</addr-line>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Montreal, Quebec</wicri:regionArea>
<wicri:noRegion>Quebec</wicri:noRegion>
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<nlm:aff id="au4">
<institution>Getulio Vargas University Hospital, Federal University of Amazonas</institution>
<addr-line>Manaus, Amazonas, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Manaus, Amazonas</wicri:regionArea>
<wicri:noRegion>Amazonas</wicri:noRegion>
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<nlm:aff id="au5">
<institution>Department of Nephrology and Hypertension, Hannover Medical School</institution>
<addr-line>Hannover, Germany</addr-line>
</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Hannover</wicri:regionArea>
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<nlm:aff id="au6">
<institution>School of Medicine, University of Queensland</institution>
<addr-line>Brisbane, Queensland, Australia</addr-line>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Brisbane, Queensland</wicri:regionArea>
<wicri:noRegion>Queensland</wicri:noRegion>
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</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Cambridge</wicri:regionArea>
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<name sortKey="Kanji, Salmaan" sort="Kanji, Salmaan" uniqKey="Kanji S" first="Salmaan" last="Kanji">Salmaan Kanji</name>
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<nlm:aff id="au8">
<institution>The Ottawa Hospital Research Institute, The Ottawa Hospital</institution>
<addr-line>Ottawa, Ontario, Canada</addr-line>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Ottawa, Ontario</wicri:regionArea>
<wicri:noRegion>Ontario</wicri:noRegion>
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<author>
<name sortKey="Mowry, James B" sort="Mowry, James B" uniqKey="Mowry J" first="James B" last="Mowry">James B. Mowry</name>
<affiliation wicri:level="2">
<nlm:aff id="au9">
<institution>Indiana University Health, Indiana Poison Center</institution>
<addr-line>Indianapolis, Indiana</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Indiana</region>
</placeName>
<wicri:cityArea>Indianapolis</wicri:cityArea>
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<author>
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<affiliation wicri:level="2">
<nlm:aff id="au10">
<institution>Division of Medical Toxicology, Department of Emergency Medicine, Morristown Medical Center</institution>
<addr-line>Morristown, New Jersey</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">New Jersey</region>
</placeName>
<wicri:cityArea>Morristown</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Hoffman, Robert S" sort="Hoffman, Robert S" uniqKey="Hoffman R" first="Robert S" last="Hoffman">Robert S. Hoffman</name>
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<nlm:aff id="au11">
<institution>Division of Medical Toxicology, Department of Emergency Medicine, New York University School of Medicine</institution>
<addr-line>New York City, New York</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">État de New York</region>
</placeName>
<wicri:cityArea>New York City</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Gosselin, Sophie" sort="Gosselin, Sophie" uniqKey="Gosselin S" first="Sophie" last="Gosselin">Sophie Gosselin</name>
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<nlm:aff id="au12">
<institution>Department of Emergency Medicine, Medical Toxicology Service, McGill University Health Centre, McGill University</institution>
<addr-line>Montreal, Quebec, Canada</addr-line>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Montreal, Quebec</wicri:regionArea>
<wicri:noRegion>Quebec</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Nolin, Thomas D" sort="Nolin, Thomas D" uniqKey="Nolin T" first="Thomas D" last="Nolin">Thomas D. Nolin</name>
<affiliation wicri:level="2">
<nlm:aff id="au13">
<institution>Department of Pharmacy and Therapeutics, Center for Clinical Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy</institution>
<addr-line>Pittsburgh, Pennsylvania</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>Pittsburgh</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Goldfarb, David S" sort="Goldfarb, David S" uniqKey="Goldfarb D" first="David S" last="Goldfarb">David S. Goldfarb</name>
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<nlm:aff id="au14">
<institution>Nephrology, NYU Langone Medical Center, NYU School of Medicine</institution>
<addr-line>New York City, New York</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">État de New York</region>
</placeName>
<wicri:cityArea>New York City</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Burdmann, Emmanuel A" sort="Burdmann, Emmanuel A" uniqKey="Burdmann E" first="Emmanuel A" last="Burdmann">Emmanuel A. Burdmann</name>
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<nlm:aff id="au15">
<institution>Division of Nephrology, University of Sao Paulo Medical School</institution>
<addr-line>Sao Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Sao Paulo</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Dargan, Paul I" sort="Dargan, Paul I" uniqKey="Dargan P" first="Paul I" last="Dargan">Paul I. Dargan</name>
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<nlm:aff id="au16">
<institution>Guy's and St Thomas' NHS Foundation Trust</institution>
<addr-line>London, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>London</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Decker, Brian Scott" sort="Decker, Brian Scott" uniqKey="Decker B" first="Brian Scott" last="Decker">Brian Scott Decker</name>
<affiliation wicri:level="2">
<nlm:aff id="au17">
<institution>Division of Nephrology, Indiana University School of Medicine</institution>
<addr-line>Indianapolis, Indiana</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Indiana</region>
</placeName>
<wicri:cityArea>Indianapolis</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Hoegberg, Lotte C" sort="Hoegberg, Lotte C" uniqKey="Hoegberg L" first="Lotte C" last="Hoegberg">Lotte C. Hoegberg</name>
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<nlm:aff id="au18">
<institution>Danish Poisons Information Centre, Anaesthesiology Bispebjerg University Hospital</institution>
<addr-line>Copenhagen, Denmark</addr-line>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Copenhagen</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Maclaren, Robert" sort="Maclaren, Robert" uniqKey="Maclaren R" first="Robert" last="Maclaren">Robert Maclaren</name>
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<nlm:aff id="au19">
<institution>University of Colorado School of Pharmacy, Clinical Pharmacy</institution>
<addr-line>Aurora, Colorado</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Colorado</region>
</placeName>
<wicri:cityArea>Aurora</wicri:cityArea>
</affiliation>
</author>
<author>
<name sortKey="Megarbane, Bruno" sort="Megarbane, Bruno" uniqKey="Megarbane B" first="Bruno" last="Megarbane">Bruno Megarbane</name>
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<nlm:aff id="au20">
<institution>Hôpital Lariboisière, Réanimation Médicale et Toxicologique, INSERM U1144, Université Paris-Diderot</institution>
<addr-line>Paris, France</addr-line>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Paris</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Sowinski, Kevin M" sort="Sowinski, Kevin M" uniqKey="Sowinski K" first="Kevin M" last="Sowinski">Kevin M. Sowinski</name>
<affiliation wicri:level="2">
<nlm:aff id="au21">
<institution>Department of Pharmacy Practice, College of Pharmacy, Purdue University</institution>
<addr-line>West Lafayette/Indianapolis, Indiana</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">Indiana</region>
</placeName>
<wicri:cityArea>West Lafayette/Indianapolis</wicri:cityArea>
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</author>
<author>
<name sortKey="Yates, Christopher" sort="Yates, Christopher" uniqKey="Yates C" first="Christopher" last="Yates">Christopher Yates</name>
<affiliation wicri:level="1">
<nlm:aff id="au22">
<institution>Emergency Department and Clinical Toxicology Unit, Hospital Universitari Son Espases</institution>
<addr-line>Mallorca, Spain</addr-line>
</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Mallorca</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Mactier, Robert" sort="Mactier, Robert" uniqKey="Mactier R" first="Robert" last="Mactier">Robert Mactier</name>
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<nlm:aff id="au23">
<institution>Greater Glasgow & Clyde, Renal Services</institution>
<addr-line>Glasgow, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Glasgow</wicri:regionArea>
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</author>
<author>
<name sortKey="Wiegand, Timothy" sort="Wiegand, Timothy" uniqKey="Wiegand T" first="Timothy" last="Wiegand">Timothy Wiegand</name>
<affiliation wicri:level="2">
<nlm:aff id="au24">
<institution>The University of Rochester Medical Center and Strong Memorial Hospital</institution>
<addr-line>Rochester, New York</addr-line>
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<country xml:lang="fr">États-Unis</country>
<placeName>
<region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Rochester</wicri:cityArea>
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</author>
<author>
<name sortKey="Ghannoum, Marc" sort="Ghannoum, Marc" uniqKey="Ghannoum M" first="Marc" last="Ghannoum">Marc Ghannoum</name>
<affiliation wicri:level="1">
<nlm:aff id="au26">
<institution>Department of Nephrology, Verdun Hospital, University of Montreal</institution>
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</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Verdun, Quebec</wicri:regionArea>
<wicri:noRegion>Quebec</wicri:noRegion>
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<series>
<title level="j">Seminars in Dialysis</title>
<idno type="ISSN">0894-0959</idno>
<idno type="eISSN">1525-139X</idno>
<imprint>
<date when="2014">2014</date>
</imprint>
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<front>
<div type="abstract" xml:lang="en">
<p>A literature review performed by the
<bold>EX</bold>
tracorporeal
<bold>TR</bold>
eatments
<bold>I</bold>
n
<bold>P</bold>
oisoning (EXTRIP) workgroup highlighted deficiencies in the existing literature, especially the reporting of case studies. Although general reporting guidelines exist for case studies, there are none in the specific field of extracorporeal treatments in toxicology. Our goal was to construct and propose a checklist that systematically outlines the minimum essential items to be reported in a case study of poisoned patients undergoing extracorporeal treatments. Through a modified two-round Delphi technique, panelists (mostly chosen from the EXTRIP workgroup) were asked to vote on the pertinence of a set of items to identify those considered minimally essential for reporting complete and accurate case reports. Furthermore, independent raters validated the clarity of each selected items between each round of voting. All case reports containing data on extracorporeal treatments in poisoning published in Medline in 2011 were reviewed during the external validation rounds. Twenty-one panelists (20 from the EXTRIP workgroup and an invited expert on pharmacology reporting guidelines) participated in the modified Delphi technique. This group included journal editors and experts in nephrology, clinical toxicology, critical care medicine, emergency medicine, and clinical pharmacology. Three independent raters participated in the validation rounds. Panelists voted on a total of 144 items in the first round and 137 items in the second round, with response rates of 96.3% and 98.3%, respectively. Twenty case reports were evaluated at each validation round and the independent raters' response rate was 99.6% and 98.8% per validation round. The final checklist consists of 114 items considered essential for case study reporting. This methodology of alternate voting and external validation rounds was useful in developing the first reporting guideline for case studies in the field of extracorporeal treatments in poisoning. We believe that this guideline will improve the completeness and transparency of published case reports and that the systematic aggregation of information from case reports may provide early signals of effectiveness and/or harm, thereby improving healthcare decision-making.</p>
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