Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data.
Identifieur interne : 003A45 ( Main/Merge ); précédent : 003A44; suivant : 003A46Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data.
Auteurs : Stella G. Muthuri [Royaume-Uni] ; Sudhir Venkatesan [Royaume-Uni] ; Puja R. Myles [Royaume-Uni] ; Jo Leonardi-Bee [Royaume-Uni] ; Tarig S A. Al Khuwaitir [Arabie saoudite] ; Adbullah Al Mamun [Bangladesh] ; Ashish P. Anovadiya [Inde] ; Eduardo Azziz-Baumgartner [États-Unis] ; Clarisa Báez [Argentine] ; Matteo Bassetti [Italie] ; Bojana Beovic [Slovénie] ; Barbara Bertisch [Suisse] ; Isabelle Bonmarin [France] ; Robert Booy [Australie] ; Victor H. Borja-Aburto [Mexique] ; Heinz Burgmann [Autriche] ; Bin Cao [République populaire de Chine] ; Jordi Carratala [Espagne] ; Justin T. Denholm [Australie] ; Samuel R. Dominguez [États-Unis] ; Pericles A D. Duarte [Brésil] ; Gal Dubnov-Raz [Israël] ; Marcela Echavarria [Argentine] ; Sergio Fanella [Canada] ; Zhancheng Gao [République populaire de Chine] ; Patrick Gérardin [France] ; Maddalena Giannella [Espagne] ; Sophie Gubbels [Danemark] ; Jethro Herberg [Royaume-Uni] ; Anjarath L Higuera Iglesias [Mexique] ; Peter H. Hoger [Allemagne] ; Xiaoyun Hu [République populaire de Chine] ; Quazi T. Islam [Bangladesh] ; Mirela F. Jiménez [Brésil] ; Amr Kandeel [Égypte] ; Gerben Keijzers [Australie] ; Hossein Khalili [Iran] ; Marian Knight [Royaume-Uni] ; Koichiro Kudo [Japon] ; Gabriela Kusznierz [Argentine] ; Ilija Kuzman [Croatie] ; Arthur M C. Kwan [Hong Kong] ; Idriss Lahlou Amine [Maroc] ; Eduard Langenegger [Afrique du Sud] ; Kamran B. Lankarani [Iran] ; Yee-Sin Leo [Singapour] ; Rita Linko [Finlande] ; Pei Liu [République populaire de Chine] ; Faris Madanat [Jordanie] ; Elga Mayo-Montero [Espagne] ; Allison Mcgeer [Canada] ; Ziad Memish [Arabie saoudite] ; Gokhan Metan [Turquie] ; Auks Mickiene [Lituanie] ; Dragan Miki [Serbie] ; Kristin G I. Mohn [Norvège] ; Ahmadreza Moradi [Iran] ; Pagbajabyn Nymadawa [Mongolie] ; Maria E. Oliva [Argentine] ; Mehpare Ozkan [Turquie] ; Dhruv Parekh [Royaume-Uni] ; Mical Paul [Israël] ; Fernando P. Polack [Argentine] ; Barbara A. Rath [Allemagne] ; Alejandro H. Rodríguez [Espagne] ; Elena B. Sarrouf [Argentine] ; Anna C. Seale [Royaume-Uni] ; Bunyamin Sertogullarindan [Turquie] ; Marilda M. Siqueira [Brésil] ; Joanna Skr T-Magierło [Pologne] ; Frank Stephan [Suisse] ; Ewa Talarek [Pologne] ; Julian W. Tang [Canada] ; Kelvin K W. To [Hong Kong] ; Antoni Torres [Espagne] ; Selda H. Törün [Turquie] ; Dat Tran [Canada] ; Timothy M. Uyeki [États-Unis] ; Annelies Van Zwol [Pays-Bas] ; Wendy Vaudry [Canada] ; Tjasa Vidmar [Slovénie] ; Renata T C. Yokota [Brésil] ; Paul Zarogoulidis [Grèce] ; Jonathan S. Nguyen-Van-Tam [Royaume-Uni]Source :
- The Lancet. Respiratory medicine [ 2213-2619 ] ; 2014.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Antienzymes (usage thérapeutique), Antiviraux (usage thérapeutique), Enfant, Femelle, Grippe humaine (mortalité), Grippe humaine (traitement médicamenteux), Hospitalisation, Humains, Jeune adulte, Modèles de hasards proportionnels, Mâle, Oséltamivir (usage thérapeutique), Pandémies, Résultat thérapeutique, Sialidase (antagonistes et inhibiteurs), Sous-type H1N1 du virus de la grippe A, Zanamivir (usage thérapeutique).
- MESH :
- antagonistes et inhibiteurs : Sialidase.
- mortalité : Grippe humaine.
- traitement médicamenteux : Grippe humaine.
- usage thérapeutique : Antienzymes, Antiviraux, Oséltamivir, Zanamivir.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Femelle, Hospitalisation, Humains, Jeune adulte, Modèles de hasards proportionnels, Mâle, Pandémies, Résultat thérapeutique, Sous-type H1N1 du virus de la grippe A.
English descriptors
- KwdEn :
- Adolescent, Adult, Antiviral Agents (therapeutic use), Child, Enzyme Inhibitors (therapeutic use), Female, Hospitalization, Humans, Influenza A Virus, H1N1 Subtype, Influenza, Human (drug therapy), Influenza, Human (mortality), Male, Middle Aged, Neuraminidase (antagonists & inhibitors), Oseltamivir (therapeutic use), Pandemics, Proportional Hazards Models, Treatment Outcome, Young Adult, Zanamivir (therapeutic use).
- MESH :
- chemical , antagonists & inhibitors : Neuraminidase.
- chemical , therapeutic use : Antiviral Agents, Enzyme Inhibitors, Oseltamivir, Zanamivir.
- drug therapy : Influenza, Human.
- mortality : Influenza, Human.
- Adolescent, Adult, Child, Female, Hospitalization, Humans, Influenza A Virus, H1N1 Subtype, Male, Middle Aged, Pandemics, Proportional Hazards Models, Treatment Outcome, Young Adult.
Abstract
Neuraminidase inhibitors were widely used during the 2009-10 influenza A H1N1 pandemic, but evidence for their effectiveness in reducing mortality is uncertain. We did a meta-analysis of individual participant data to investigate the association between use of neuraminidase inhibitors and mortality in patients admitted to hospital with pandemic influenza A H1N1pdm09 virus infection.
DOI: 10.1016/S2213-2600(14)70041-4
PubMed: 24815805
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pubmed:24815805Le document en format XML
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<author><name sortKey="Bertisch, Barbara" sort="Bertisch, Barbara" uniqKey="Bertisch B" first="Barbara" last="Bertisch">Barbara Bertisch</name>
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<author><name sortKey="Carratala, Jordi" sort="Carratala, Jordi" uniqKey="Carratala J" first="Jordi" last="Carratala">Jordi Carratala</name>
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<author><name sortKey="Dominguez, Samuel R" sort="Dominguez, Samuel R" uniqKey="Dominguez S" first="Samuel R" last="Dominguez">Samuel R. Dominguez</name>
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<author><name sortKey="Duarte, Pericles A D" sort="Duarte, Pericles A D" uniqKey="Duarte P" first="Pericles A D" last="Duarte">Pericles A D. Duarte</name>
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<author><name sortKey="Dubnov Raz, Gal" sort="Dubnov Raz, Gal" uniqKey="Dubnov Raz G" first="Gal" last="Dubnov-Raz">Gal Dubnov-Raz</name>
<affiliation wicri:level="1"><nlm:affiliation>The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
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<author><name sortKey="Echavarria, Marcela" sort="Echavarria, Marcela" uniqKey="Echavarria M" first="Marcela" last="Echavarria">Marcela Echavarria</name>
<affiliation wicri:level="1"><nlm:affiliation>Clinical Virology Laboratory, CEMIC University Hospital, Galvan, Buenos Aires, Argentina.</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>Clinical Virology Laboratory, CEMIC University Hospital, Galvan, Buenos Aires</wicri:regionArea>
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<author><name sortKey="Fanella, Sergio" sort="Fanella, Sergio" uniqKey="Fanella S" first="Sergio" last="Fanella">Sergio Fanella</name>
<affiliation wicri:level="4"><nlm:affiliation>Section of Pediatric Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Section of Pediatric Infectious Diseases, University of Manitoba, Winnipeg, MB</wicri:regionArea>
<orgName type="university">Université du Manitoba</orgName>
<placeName><settlement type="city">Winnipeg</settlement>
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<author><name sortKey="Gao, Zhancheng" sort="Gao, Zhancheng" uniqKey="Gao Z" first="Zhancheng" last="Gao">Zhancheng Gao</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gerardin, Patrick" sort="Gerardin, Patrick" uniqKey="Gerardin P" first="Patrick" last="Gérardin">Patrick Gérardin</name>
<affiliation wicri:level="1"><nlm:affiliation>Neonatal Intensive Care Unit/Paediatric Intensive Care Unit, Centre Hospitalier Universitaire-Groupe Hospitalier Sud Réunion, Saint Pierre, Réunion, France; Centre for Clinical Investigation 1410, National Institute for Health and Medical Research/Centre Hospitalier Universitaire/Université de La Réunion, Saint Pierre, Réunion, France; Unité Mixte de Recherche "Processus Infectieux en Milieu Insulaire Tropical" Université de La Réunion/Centre Hospitalier Universitaire/National Institute for Health and Medical Research/Research and Development Institute -Cyclotron Réunion Océan Indien, Saint Denis, Réunion, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
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<author><name sortKey="Giannella, Maddalena" sort="Giannella, Maddalena" uniqKey="Giannella M" first="Maddalena" last="Giannella">Maddalena Giannella</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
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<author><name sortKey="Gubbels, Sophie" sort="Gubbels, Sophie" uniqKey="Gubbels S" first="Sophie" last="Gubbels">Sophie Gubbels</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Disease Epidemiology, Sector for National Health Documentation and Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Department of Infectious Disease Epidemiology, Sector for National Health Documentation and Research, Statens Serum Institut, Copenhagen</wicri:regionArea>
<placeName><settlement type="city">Copenhague</settlement>
<region type="région" nuts="2">Hovedstaden</region>
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<author><name sortKey="Herberg, Jethro" sort="Herberg, Jethro" uniqKey="Herberg J" first="Jethro" last="Herberg">Jethro Herberg</name>
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<country xml:lang="fr">Royaume-Uni</country>
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</affiliation>
</author>
<author><name sortKey="Iglesias, Anjarath L Higuera" sort="Iglesias, Anjarath L Higuera" uniqKey="Iglesias A" first="Anjarath L Higuera" last="Iglesias">Anjarath L Higuera Iglesias</name>
<affiliation wicri:level="1"><nlm:affiliation>Epidemiology Research Unit, Instituto Nacional de Enfermedades Respiratorias, Ismael Cosío Villegas, Mexico City, Mexico.</nlm:affiliation>
<country xml:lang="fr">Mexique</country>
<wicri:regionArea>Epidemiology Research Unit, Instituto Nacional de Enfermedades Respiratorias, Ismael Cosío Villegas, Mexico City</wicri:regionArea>
<wicri:noRegion>Mexico City</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hoger, Peter H" sort="Hoger, Peter H" uniqKey="Hoger P" first="Peter H" last="Hoger">Peter H. Hoger</name>
<affiliation wicri:level="3"><nlm:affiliation>Catholic Children's Hospital Wilhelmstift, Liliencronstr, Hamburg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Catholic Children's Hospital Wilhelmstift, Liliencronstr, Hamburg</wicri:regionArea>
<placeName><settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hu, Xiaoyun" sort="Hu, Xiaoyun" uniqKey="Hu X" first="Xiaoyun" last="Hu">Xiaoyun Hu</name>
<affiliation wicri:level="3"><nlm:affiliation>Peking Union Medical College Hospital, Beijing, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Peking Union Medical College Hospital, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Islam, Quazi T" sort="Islam, Quazi T" uniqKey="Islam Q" first="Quazi T" last="Islam">Quazi T. Islam</name>
<affiliation wicri:level="1"><nlm:affiliation>Dhaka Medical College Hospital, Dhaka, Bangladesh.</nlm:affiliation>
<country xml:lang="fr">Bangladesh</country>
<wicri:regionArea>Dhaka Medical College Hospital, Dhaka</wicri:regionArea>
<wicri:noRegion>Dhaka</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jimenez, Mirela F" sort="Jimenez, Mirela F" uniqKey="Jimenez M" first="Mirela F" last="Jiménez">Mirela F. Jiménez</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Ginecologia e Obstetrícia, Universidade Federal de Ciências da Saúde de Porto Alegre, Preceptora da Residência Médica do Hospital Fêmina, Porto Alegre, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Ginecologia e Obstetrícia, Universidade Federal de Ciências da Saúde de Porto Alegre, Preceptora da Residência Médica do Hospital Fêmina, Porto Alegre</wicri:regionArea>
<placeName><settlement type="city">Porto Alegre</settlement>
<region type="state">Rio Grande do Sul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kandeel, Amr" sort="Kandeel, Amr" uniqKey="Kandeel A" first="Amr" last="Kandeel">Amr Kandeel</name>
<affiliation wicri:level="1"><nlm:affiliation>Ministry of Health in Egypt, Cairo, Egypt.</nlm:affiliation>
<country xml:lang="fr">Égypte</country>
<wicri:regionArea>Ministry of Health in Egypt, Cairo</wicri:regionArea>
<wicri:noRegion>Cairo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Keijzers, Gerben" sort="Keijzers, Gerben" uniqKey="Keijzers G" first="Gerben" last="Keijzers">Gerben Keijzers</name>
<affiliation wicri:level="1"><nlm:affiliation>Gold Coast Hospital, Gold Coast, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Gold Coast Hospital, Gold Coast, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Khalili, Hossein" sort="Khalili, Hossein" uniqKey="Khalili H" first="Hossein" last="Khalili">Hossein Khalili</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran</wicri:regionArea>
<wicri:noRegion>Tehran</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Knight, Marian" sort="Knight, Marian" uniqKey="Knight M" first="Marian" last="Knight">Marian Knight</name>
<affiliation wicri:level="4"><nlm:affiliation>National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford</wicri:regionArea>
<placeName><settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
<author><name sortKey="Kudo, Koichiro" sort="Kudo, Koichiro" uniqKey="Kudo K" first="Koichiro" last="Kudo">Koichiro Kudo</name>
<affiliation wicri:level="3"><nlm:affiliation>National Center for Global Health and Medicine, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>National Center for Global Health and Medicine, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
<region type="région">Région de Kantō</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kusznierz, Gabriela" sort="Kusznierz, Gabriela" uniqKey="Kusznierz G" first="Gabriela" last="Kusznierz">Gabriela Kusznierz</name>
<affiliation wicri:level="1"><nlm:affiliation>National Institute of Respiratory Diseases, 'Dr Emilio Coni', Santa Fe, Argentina.</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>National Institute of Respiratory Diseases, 'Dr Emilio Coni', Santa Fe</wicri:regionArea>
<wicri:noRegion>Santa Fe</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kuzman, Ilija" sort="Kuzman, Ilija" uniqKey="Kuzman I" first="Ilija" last="Kuzman">Ilija Kuzman</name>
<affiliation wicri:level="1"><nlm:affiliation>University Hospital for Infectious Diseases, University of Zagreb, School of Medicine, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>University Hospital for Infectious Diseases, University of Zagreb, School of Medicine, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kwan, Arthur M C" sort="Kwan, Arthur M C" uniqKey="Kwan A" first="Arthur M C" last="Kwan">Arthur M C. Kwan</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Intensive Care, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong, Hong Kong.</nlm:affiliation>
<country xml:lang="fr">Hong Kong</country>
<wicri:regionArea>Department of Intensive Care, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong</wicri:regionArea>
<wicri:noRegion>Hong Kong</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Amine, Idriss Lahlou" sort="Amine, Idriss Lahlou" uniqKey="Amine I" first="Idriss Lahlou" last="Amine">Idriss Lahlou Amine</name>
<affiliation wicri:level="3"><nlm:affiliation>University Mohammed V-Souissi, Faculty of Medicine and Pharmacy, Mohammed V Military Teaching Hospital, Biosafety Level 3 and Research Laboratory, Rabat, Morocco.</nlm:affiliation>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea>University Mohammed V-Souissi, Faculty of Medicine and Pharmacy, Mohammed V Military Teaching Hospital, Biosafety Level 3 and Research Laboratory, Rabat</wicri:regionArea>
<placeName><settlement type="city">Rabat</settlement>
<region nuts="2">Rabat-Salé-Kénitra</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Langenegger, Eduard" sort="Langenegger, Eduard" uniqKey="Langenegger E" first="Eduard" last="Langenegger">Eduard Langenegger</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynaecology, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>Department of Obstetrics and Gynaecology, Stellenbosch University and Tygerberg Hospital, Cape Town</wicri:regionArea>
<wicri:noRegion>Cape Town</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lankarani, Kamran B" sort="Lankarani, Kamran B" uniqKey="Lankarani K" first="Kamran B" last="Lankarani">Kamran B. Lankarani</name>
<affiliation wicri:level="1"><nlm:affiliation>Health Policy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>Health Policy Research Center, Shiraz University of Medical Sciences, Shiraz</wicri:regionArea>
<wicri:noRegion>Shiraz</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Leo, Yee Sin" sort="Leo, Yee Sin" uniqKey="Leo Y" first="Yee-Sin" last="Leo">Yee-Sin Leo</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.</nlm:affiliation>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea>Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore</wicri:regionArea>
<wicri:noRegion>Singapore</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Linko, Rita" sort="Linko, Rita" uniqKey="Linko R" first="Rita" last="Linko">Rita Linko</name>
<affiliation wicri:level="1"><nlm:affiliation>Helsinki University Hospital, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Helsinki University Hospital, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Liu, Pei" sort="Liu, Pei" uniqKey="Liu P" first="Pei" last="Liu">Pei Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Diseases, the First Affiliated Hospital, China Medical University, Shenyang, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Infectious Diseases, the First Affiliated Hospital, China Medical University, Shenyang</wicri:regionArea>
<wicri:noRegion>Shenyang</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Madanat, Faris" sort="Madanat, Faris" uniqKey="Madanat F" first="Faris" last="Madanat">Faris Madanat</name>
<affiliation wicri:level="1"><nlm:affiliation>King Hussein Cancer Center, Department of Pediatrics, Amman, Jordan.</nlm:affiliation>
<country xml:lang="fr">Jordanie</country>
<wicri:regionArea>King Hussein Cancer Center, Department of Pediatrics, Amman</wicri:regionArea>
<wicri:noRegion>Amman</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mayo Montero, Elga" sort="Mayo Montero, Elga" uniqKey="Mayo Montero E" first="Elga" last="Mayo-Montero">Elga Mayo-Montero</name>
<affiliation wicri:level="3"><nlm:affiliation>Instituto de Medicina Preventiva de la Defensa, Capitan Medico Ramon y Cajal, Ministerio de Defensa, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Instituto de Medicina Preventiva de la Defensa, Capitan Medico Ramon y Cajal, Ministerio de Defensa, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcgeer, Allison" sort="Mcgeer, Allison" uniqKey="Mcgeer A" first="Allison" last="Mcgeer">Allison Mcgeer</name>
<affiliation wicri:level="4"><nlm:affiliation>Toronto Invasive Bacterial Diseases Network, University of Toronto, Toronto, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Toronto Invasive Bacterial Diseases Network, University of Toronto, Toronto, ON</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Memish, Ziad" sort="Memish, Ziad" uniqKey="Memish Z" first="Ziad" last="Memish">Ziad Memish</name>
<affiliation wicri:level="1"><nlm:affiliation>Ministry of Health, Riyadh, Saudi Arabia; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.</nlm:affiliation>
<country xml:lang="fr">Arabie saoudite</country>
<wicri:regionArea>Ministry of Health, Riyadh, Saudi Arabia; College of Medicine, Alfaisal University, Riyadh</wicri:regionArea>
<wicri:noRegion>Riyadh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Metan, Gokhan" sort="Metan, Gokhan" uniqKey="Metan G" first="Gokhan" last="Metan">Gokhan Metan</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Diseases and Clinical Microbiology, Erciyes University Faculty of Medicine, Kayseri, Turkey.</nlm:affiliation>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Department of Infectious Diseases and Clinical Microbiology, Erciyes University Faculty of Medicine, Kayseri</wicri:regionArea>
<wicri:noRegion>Kayseri</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mickiene, Auks" sort="Mickiene, Auks" uniqKey="Mickiene A" first="Auks" last="Mickiene">Auks Mickiene</name>
<affiliation wicri:level="1"><nlm:affiliation>Lithuanian University of Health Sciences, Kaunas, Lithuania.</nlm:affiliation>
<country xml:lang="fr">Lituanie</country>
<wicri:regionArea>Lithuanian University of Health Sciences, Kaunas</wicri:regionArea>
<wicri:noRegion>Kaunas</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Miki, Dragan" sort="Miki, Dragan" uniqKey="Miki D" first="Dragan" last="Miki">Dragan Miki</name>
<affiliation wicri:level="1"><nlm:affiliation>Military Medical Academy, Clinic for Infectious and Tropical Diseases, Belgrade, Serbia.</nlm:affiliation>
<country xml:lang="fr">Serbie</country>
<wicri:regionArea>Military Medical Academy, Clinic for Infectious and Tropical Diseases, Belgrade</wicri:regionArea>
<wicri:noRegion>Belgrade</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mohn, Kristin G I" sort="Mohn, Kristin G I" uniqKey="Mohn K" first="Kristin G I" last="Mohn">Kristin G I. Mohn</name>
<affiliation wicri:level="1"><nlm:affiliation>Section for Infectious Diseases, Medical Department, and Department of Research and Development, Haukeland University Hospital, Bergen, Norway; The Influenza Centre, Department of Clinical Science, University of Bergen, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Section for Infectious Diseases, Medical Department, and Department of Research and Development, Haukeland University Hospital, Bergen, Norway; The Influenza Centre, Department of Clinical Science, University of Bergen, Bergen</wicri:regionArea>
<wicri:noRegion>Bergen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Moradi, Ahmadreza" sort="Moradi, Ahmadreza" uniqKey="Moradi A" first="Ahmadreza" last="Moradi">Ahmadreza Moradi</name>
<affiliation wicri:level="1"><nlm:affiliation>The Division of Ocular Immunology, Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; National Research Institute for Tuberculosis and Lung Disease, Massih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>The Division of Ocular Immunology, Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; National Research Institute for Tuberculosis and Lung Disease, Massih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran</wicri:regionArea>
<wicri:noRegion>Tehran</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nymadawa, Pagbajabyn" sort="Nymadawa, Pagbajabyn" uniqKey="Nymadawa P" first="Pagbajabyn" last="Nymadawa">Pagbajabyn Nymadawa</name>
<affiliation wicri:level="1"><nlm:affiliation>National Influenza Center, National Center of Communicable Diseases, Ministry of Health, Ulaanbaatar, Mongolia.</nlm:affiliation>
<country xml:lang="fr">Mongolie</country>
<wicri:regionArea>National Influenza Center, National Center of Communicable Diseases, Ministry of Health, Ulaanbaatar</wicri:regionArea>
<wicri:noRegion>Ulaanbaatar</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Oliva, Maria E" sort="Oliva, Maria E" uniqKey="Oliva M" first="Maria E" last="Oliva">Maria E. Oliva</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infection Control, Hospital San Martín de Paraná, Entre Ríos, Argentina.</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>Department of Infection Control, Hospital San Martín de Paraná, Entre Ríos</wicri:regionArea>
<wicri:noRegion>Entre Ríos</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ozkan, Mehpare" sort="Ozkan, Mehpare" uniqKey="Ozkan M" first="Mehpare" last="Ozkan">Mehpare Ozkan</name>
<affiliation wicri:level="1"><nlm:affiliation>Dr Sami Ulus Research and Training Hospital of Women's and Children's Health and Diseases, Clinic of Pediatric Neurology, Ankara, Turkey.</nlm:affiliation>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Dr Sami Ulus Research and Training Hospital of Women's and Children's Health and Diseases, Clinic of Pediatric Neurology, Ankara</wicri:regionArea>
<wicri:noRegion>Ankara</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Parekh, Dhruv" sort="Parekh, Dhruv" uniqKey="Parekh D" first="Dhruv" last="Parekh">Dhruv Parekh</name>
<affiliation wicri:level="4"><nlm:affiliation>Critical Care and Pain Perioperative, Critical Care and Trauma Trials Group, School of Clinical and Experimental Medicine, University of Birmingham, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Critical Care and Pain Perioperative, Critical Care and Trauma Trials Group, School of Clinical and Experimental Medicine, University of Birmingham</wicri:regionArea>
<placeName><settlement type="city">Birmingham</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Midlands de l'Ouest</region>
</placeName>
<orgName type="university">Université de Birmingham</orgName>
</affiliation>
</author>
<author><name sortKey="Paul, Mical" sort="Paul, Mical" uniqKey="Paul M" first="Mical" last="Paul">Mical Paul</name>
<affiliation wicri:level="1"><nlm:affiliation>Division of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Division of Infectious Diseases, Rambam Health Care Campus, Haifa</wicri:regionArea>
<wicri:noRegion>Haifa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Polack, Fernando P" sort="Polack, Fernando P" uniqKey="Polack F" first="Fernando P" last="Polack">Fernando P. Polack</name>
<affiliation wicri:level="1"><nlm:affiliation>Vanderbilt Vaccine Center, Department of Pediatrics, Vanderbilt University, Nashville, TN, USA; Fundacion INFANT, Buenos Aires, Argentina.</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>Vanderbilt Vaccine Center, Department of Pediatrics, Vanderbilt University, Nashville, TN, USA; Fundacion INFANT, Buenos Aires</wicri:regionArea>
<wicri:noRegion>Buenos Aires</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rath, Barbara A" sort="Rath, Barbara A" uniqKey="Rath B" first="Barbara A" last="Rath">Barbara A. Rath</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Pediatrics, Division of Pneumonology-Immunology, Charité University Medical Center, Berlin, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Pediatrics, Division of Pneumonology-Immunology, Charité University Medical Center, Berlin</wicri:regionArea>
<placeName><region type="land" nuts="3">Berlin</region>
<settlement type="city">Berlin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rodriguez, Alejandro H" sort="Rodriguez, Alejandro H" uniqKey="Rodriguez A" first="Alejandro H" last="Rodríguez">Alejandro H. Rodríguez</name>
<affiliation wicri:level="1"><nlm:affiliation>Hospital Joan XXIII, Critical Care Department, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Ciber De Enfermedades Respiratorias, Tarragona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Hospital Joan XXIII, Critical Care Department, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Ciber De Enfermedades Respiratorias, Tarragona</wicri:regionArea>
<wicri:noRegion>Tarragona</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sarrouf, Elena B" sort="Sarrouf, Elena B" uniqKey="Sarrouf E" first="Elena B" last="Sarrouf">Elena B. Sarrouf</name>
<affiliation wicri:level="1"><nlm:affiliation>Ministerio de Salud de Tucumán, Tucumán, Argentina.</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>Ministerio de Salud de Tucumán, Tucumán</wicri:regionArea>
<wicri:noRegion>Tucumán</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Seale, Anna C" sort="Seale, Anna C" uniqKey="Seale A" first="Anna C" last="Seale">Anna C. Seale</name>
<affiliation wicri:level="1"><nlm:affiliation>Paediatric Intensive Care Unit, Bristol Children's Hospital, Bristol, UK; Bristol Children's Vaccine Centre, School of Clinical Sciences, University of Bristol, Bristol, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Paediatric Intensive Care Unit, Bristol Children's Hospital, Bristol, UK; Bristol Children's Vaccine Centre, School of Clinical Sciences, University of Bristol, Bristol</wicri:regionArea>
<wicri:noRegion>Bristol</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sertogullarindan, Bunyamin" sort="Sertogullarindan, Bunyamin" uniqKey="Sertogullarindan B" first="Bunyamin" last="Sertogullarindan">Bunyamin Sertogullarindan</name>
<affiliation wicri:level="1"><nlm:affiliation>Yuzuncu Yil University Medical Faculty, Department of Pulmonary Medicine, Van, Turkey.</nlm:affiliation>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Yuzuncu Yil University Medical Faculty, Department of Pulmonary Medicine, Van</wicri:regionArea>
<wicri:noRegion>Van</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Siqueira, Marilda M" sort="Siqueira, Marilda M" uniqKey="Siqueira M" first="Marilda M" last="Siqueira">Marilda M. Siqueira</name>
<affiliation wicri:level="3"><nlm:affiliation>Laboratory of Respiratory Viruses, Oswaldo Cruz Institute/Fiocruz, Rio de Janeiro, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Laboratory of Respiratory Viruses, Oswaldo Cruz Institute/Fiocruz, Rio de Janeiro</wicri:regionArea>
<placeName><settlement type="city">Rio de Janeiro</settlement>
<region type="state">État de Rio de Janeiro</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Skr T Magierlo, Joanna" sort="Skr T Magierlo, Joanna" uniqKey="Skr T Magierlo J" first="Joanna" last="Skr T-Magierło">Joanna Skr T-Magierło</name>
<affiliation wicri:level="1"><nlm:affiliation>Uniwersytet Rzeszowski, Rzeszów, Poland.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>Uniwersytet Rzeszowski, Rzeszów</wicri:regionArea>
<wicri:noRegion>Rzeszów</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stephan, Frank" sort="Stephan, Frank" uniqKey="Stephan F" first="Frank" last="Stephan">Frank Stephan</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Emergency Medicine, University Hospital Basel, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Emergency Medicine, University Hospital Basel, Basel</wicri:regionArea>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Talarek, Ewa" sort="Talarek, Ewa" uniqKey="Talarek E" first="Ewa" last="Talarek">Ewa Talarek</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Children's Infectious Diseases, Medical University of Warsaw, Warsaw, Poland.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>Department of Children's Infectious Diseases, Medical University of Warsaw, Warsaw</wicri:regionArea>
<wicri:noRegion>Warsaw</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tang, Julian W" sort="Tang, Julian W" uniqKey="Tang J" first="Julian W" last="Tang">Julian W. Tang</name>
<affiliation wicri:level="1"><nlm:affiliation>Division of Microbiology, Molecular Diagnostic Centre, Department of Laboratory Medicine National University Hospital, Singapore, Singapore; Alberta Provincial Laboratory for Public Health, University of Alberta Hospital, Edmonton, AB, Canada; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Division of Microbiology, Molecular Diagnostic Centre, Department of Laboratory Medicine National University Hospital, Singapore, Singapore; Alberta Provincial Laboratory for Public Health, University of Alberta Hospital, Edmonton, AB, Canada; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB</wicri:regionArea>
<wicri:noRegion>AB</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="To, Kelvin K W" sort="To, Kelvin K W" uniqKey="To K" first="Kelvin K W" last="To">Kelvin K W. To</name>
<affiliation wicri:level="1"><nlm:affiliation>Carol Yu Centre for Infection and Division of Infectious Diseases, Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong.</nlm:affiliation>
<country xml:lang="fr">Hong Kong</country>
<wicri:regionArea>Carol Yu Centre for Infection and Division of Infectious Diseases, Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea>
<wicri:noRegion>Queen Mary Hospital</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Torres, Antoni" sort="Torres, Antoni" uniqKey="Torres A" first="Antoni" last="Torres">Antoni Torres</name>
<affiliation wicri:level="3"><nlm:affiliation>Hospital Clinic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Ciber De Enfermedades Respiratorias, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Hospital Clinic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Ciber De Enfermedades Respiratorias, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Torun, Selda H" sort="Torun, Selda H" uniqKey="Torun S" first="Selda H" last="Törün">Selda H. Törün</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatric Infectious Diseases, Istanbul Medical Faculty, Istanbul, Turkey.</nlm:affiliation>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Department of Pediatric Infectious Diseases, Istanbul Medical Faculty, Istanbul</wicri:regionArea>
<wicri:noRegion>Istanbul</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tran, Dat" sort="Tran, Dat" uniqKey="Tran D" first="Dat" last="Tran">Dat Tran</name>
<affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Division of Infectious Diseases, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Uyeki, Timothy M" sort="Uyeki, Timothy M" uniqKey="Uyeki T" first="Timothy M" last="Uyeki">Timothy M. Uyeki</name>
<affiliation wicri:level="2"><nlm:affiliation>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Van Zwol, Annelies" sort="Van Zwol, Annelies" uniqKey="Van Zwol A" first="Annelies" last="Van Zwol">Annelies Van Zwol</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Pediatric Intensive Care, VU University Medical Center, Amsterdam, Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Pediatric Intensive Care, VU University Medical Center, Amsterdam</wicri:regionArea>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Vaudry, Wendy" sort="Vaudry, Wendy" uniqKey="Vaudry W" first="Wendy" last="Vaudry">Wendy Vaudry</name>
<affiliation wicri:level="1"><nlm:affiliation>Division of Infectious Diseases, Department of Pediatrics, University of Alberta, Stollery Children's Hospital, Edmonton, AB, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Division of Infectious Diseases, Department of Pediatrics, University of Alberta, Stollery Children's Hospital, Edmonton, AB</wicri:regionArea>
<wicri:noRegion>AB</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vidmar, Tjasa" sort="Vidmar, Tjasa" uniqKey="Vidmar T" first="Tjasa" last="Vidmar">Tjasa Vidmar</name>
<affiliation wicri:level="1"><nlm:affiliation>General Hospital Slovenj Gradec, Slovenj Gradec, Slovenia.</nlm:affiliation>
<country xml:lang="fr">Slovénie</country>
<wicri:regionArea>General Hospital Slovenj Gradec, Slovenj Gradec</wicri:regionArea>
<wicri:noRegion>Slovenj Gradec</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Yokota, Renata T C" sort="Yokota, Renata T C" uniqKey="Yokota R" first="Renata T C" last="Yokota">Renata T C. Yokota</name>
<affiliation wicri:level="2"><nlm:affiliation>Departamento de Vigilância Epidemiológica, Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília DF, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Vigilância Epidemiológica, Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília DF</wicri:regionArea>
<placeName><region type="state">District fédéral (Brésil)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zarogoulidis, Paul" sort="Zarogoulidis, Paul" uniqKey="Zarogoulidis P" first="Paul" last="Zarogoulidis">Paul Zarogoulidis</name>
<affiliation wicri:level="1"><nlm:affiliation>Unit of Infectious Diseases, University General Hospital of Alexandroupolis, Democritus University Thrace, Dragana, Greece.</nlm:affiliation>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Unit of Infectious Diseases, University General Hospital of Alexandroupolis, Democritus University Thrace, Dragana</wicri:regionArea>
<wicri:noRegion>Dragana</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nguyen Van Tam, Jonathan S" sort="Nguyen Van Tam, Jonathan S" uniqKey="Nguyen Van Tam J" first="Jonathan S" last="Nguyen-Van-Tam">Jonathan S. Nguyen-Van-Tam</name>
<affiliation wicri:level="4"><nlm:affiliation>Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK. Electronic address: jvt@nottingham.ac.uk.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Division of Epidemiology and Public Health, University of Nottingham, Nottingham</wicri:regionArea>
<orgName type="university">Université de Nottingham</orgName>
<placeName><settlement type="city">Nottingham</settlement>
<region type="nation">Angleterre</region>
<region type="région" nuts="1">Nottinghamshire</region>
</placeName>
</affiliation>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data.</title>
<author><name sortKey="Muthuri, Stella G" sort="Muthuri, Stella G" uniqKey="Muthuri S" first="Stella G" last="Muthuri">Stella G. Muthuri</name>
<affiliation wicri:level="4"><nlm:affiliation>Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Division of Epidemiology and Public Health, University of Nottingham, Nottingham</wicri:regionArea>
<orgName type="university">Université de Nottingham</orgName>
<placeName><settlement type="city">Nottingham</settlement>
<region type="nation">Angleterre</region>
<region type="région" nuts="1">Nottinghamshire</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Venkatesan, Sudhir" sort="Venkatesan, Sudhir" uniqKey="Venkatesan S" first="Sudhir" last="Venkatesan">Sudhir Venkatesan</name>
<affiliation wicri:level="4"><nlm:affiliation>Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Division of Epidemiology and Public Health, University of Nottingham, Nottingham</wicri:regionArea>
<orgName type="university">Université de Nottingham</orgName>
<placeName><settlement type="city">Nottingham</settlement>
<region type="nation">Angleterre</region>
<region type="région" nuts="1">Nottinghamshire</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Myles, Puja R" sort="Myles, Puja R" uniqKey="Myles P" first="Puja R" last="Myles">Puja R. Myles</name>
<affiliation wicri:level="4"><nlm:affiliation>Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Division of Epidemiology and Public Health, University of Nottingham, Nottingham</wicri:regionArea>
<orgName type="university">Université de Nottingham</orgName>
<placeName><settlement type="city">Nottingham</settlement>
<region type="nation">Angleterre</region>
<region type="région" nuts="1">Nottinghamshire</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Leonardi Bee, Jo" sort="Leonardi Bee, Jo" uniqKey="Leonardi Bee J" first="Jo" last="Leonardi-Bee">Jo Leonardi-Bee</name>
<affiliation wicri:level="4"><nlm:affiliation>Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Division of Epidemiology and Public Health, University of Nottingham, Nottingham</wicri:regionArea>
<orgName type="university">Université de Nottingham</orgName>
<placeName><settlement type="city">Nottingham</settlement>
<region type="nation">Angleterre</region>
<region type="région" nuts="1">Nottinghamshire</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Al Khuwaitir, Tarig S A" sort="Al Khuwaitir, Tarig S A" uniqKey="Al Khuwaitir T" first="Tarig S A" last="Al Khuwaitir">Tarig S A. Al Khuwaitir</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, King Saud Medical City, Riyadh, Saudi Arabia.</nlm:affiliation>
<country xml:lang="fr">Arabie saoudite</country>
<wicri:regionArea>Department of Medicine, King Saud Medical City, Riyadh</wicri:regionArea>
<wicri:noRegion>Riyadh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Al Mamun, Adbullah" sort="Al Mamun, Adbullah" uniqKey="Al Mamun A" first="Adbullah" last="Al Mamun">Adbullah Al Mamun</name>
<affiliation wicri:level="1"><nlm:affiliation>International Centre for Diarrhoeal Diseases, Research Bangladesh, Dhaka, Bangladesh.</nlm:affiliation>
<country xml:lang="fr">Bangladesh</country>
<wicri:regionArea>International Centre for Diarrhoeal Diseases, Research Bangladesh, Dhaka</wicri:regionArea>
<wicri:noRegion>Dhaka</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Anovadiya, Ashish P" sort="Anovadiya, Ashish P" uniqKey="Anovadiya A" first="Ashish P" last="Anovadiya">Ashish P. Anovadiya</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pharmacology, Government Medical College Bhavnagar, Gujarat, India; Sir Takhtsinhji General Hospital, Bhavnagar, Gujarat, India.</nlm:affiliation>
<country xml:lang="fr">Inde</country>
<wicri:regionArea>Department of Pharmacology, Government Medical College Bhavnagar, Gujarat, India; Sir Takhtsinhji General Hospital, Bhavnagar, Gujarat</wicri:regionArea>
<wicri:noRegion>Gujarat</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Azziz Baumgartner, Eduardo" sort="Azziz Baumgartner, Eduardo" uniqKey="Azziz Baumgartner E" first="Eduardo" last="Azziz-Baumgartner">Eduardo Azziz-Baumgartner</name>
<affiliation wicri:level="2"><nlm:affiliation>Centers for Disease Control and Prevention, Atlanta, GA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Baez, Clarisa" sort="Baez, Clarisa" uniqKey="Baez C" first="Clarisa" last="Báez">Clarisa Báez</name>
<affiliation wicri:level="1"><nlm:affiliation>Ministerio de Salud de la Provincia de Buenos Aires, Buenos Aires, Argentina.</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>Ministerio de Salud de la Provincia de Buenos Aires, Buenos Aires</wicri:regionArea>
<wicri:noRegion>Buenos Aires</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bassetti, Matteo" sort="Bassetti, Matteo" uniqKey="Bassetti M" first="Matteo" last="Bassetti">Matteo Bassetti</name>
<affiliation wicri:level="1"><nlm:affiliation>Santa Maria Misericordia Hospital, Udine, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Santa Maria Misericordia Hospital, Udine</wicri:regionArea>
<wicri:noRegion>Udine</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Beovic, Bojana" sort="Beovic, Bojana" uniqKey="Beovic B" first="Bojana" last="Beovic">Bojana Beovic</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Diseases, University Medical Centre, Ljubljana, Slovenia.</nlm:affiliation>
<country xml:lang="fr">Slovénie</country>
<wicri:regionArea>Department of Infectious Diseases, University Medical Centre, Ljubljana</wicri:regionArea>
<wicri:noRegion>Ljubljana</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bertisch, Barbara" sort="Bertisch, Barbara" uniqKey="Bertisch B" first="Barbara" last="Bertisch">Barbara Bertisch</name>
<affiliation wicri:level="1"><nlm:affiliation>Division of Infectious Diseases and Hospital Epidemiology, Kantonsspital St Gallen, St Gallen, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Division of Infectious Diseases and Hospital Epidemiology, Kantonsspital St Gallen, St Gallen</wicri:regionArea>
<wicri:noRegion>St Gallen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bonmarin, Isabelle" sort="Bonmarin, Isabelle" uniqKey="Bonmarin I" first="Isabelle" last="Bonmarin">Isabelle Bonmarin</name>
<affiliation wicri:level="1"><nlm:affiliation>Institut de Veille Sanitaire, Saint-Maurice, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut de Veille Sanitaire, Saint-Maurice</wicri:regionArea>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
<wicri:noRegion>Saint-Maurice</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Booy, Robert" sort="Booy, Robert" uniqKey="Booy R" first="Robert" last="Booy">Robert Booy</name>
<affiliation wicri:level="4"><nlm:affiliation>National Centre for Immunisation Research and Surveillance, The Children's Hospital at Westmead, University of Sydney, Sydney, NSW, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>National Centre for Immunisation Research and Surveillance, The Children's Hospital at Westmead, University of Sydney, Sydney, NSW</wicri:regionArea>
<orgName type="university">Université de Sydney</orgName>
<placeName><settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Borja Aburto, Victor H" sort="Borja Aburto, Victor H" uniqKey="Borja Aburto V" first="Victor H" last="Borja-Aburto">Victor H. Borja-Aburto</name>
<affiliation wicri:level="1"><nlm:affiliation>Instituto Mexicano del Seguro Social, Mexico City, Mexico.</nlm:affiliation>
<country xml:lang="fr">Mexique</country>
<wicri:regionArea>Instituto Mexicano del Seguro Social, Mexico City</wicri:regionArea>
<wicri:noRegion>Mexico City</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Burgmann, Heinz" sort="Burgmann, Heinz" uniqKey="Burgmann H" first="Heinz" last="Burgmann">Heinz Burgmann</name>
<affiliation wicri:level="3"><nlm:affiliation>Medical University of Vienna, Vienna, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Medical University of Vienna, Vienna</wicri:regionArea>
<placeName><settlement type="city">Vienne (Autriche)</settlement>
<region nuts="2" type="province">Vienne (Autriche)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Cao, Bin" sort="Cao, Bin" uniqKey="Cao B" first="Bin" last="Cao">Bin Cao</name>
<affiliation wicri:level="3"><nlm:affiliation>Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Beijing Chao-Yang Hospital, Capital Medical University, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Carratala, Jordi" sort="Carratala, Jordi" uniqKey="Carratala J" first="Jordi" last="Carratala">Jordi Carratala</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Diseases, Hospital Universitari de Bellvitge, Bellvitge Institute for Biomedical Research, L'Hospitalet de Llobregat, Red Española de Investigación en Patología Infecciosa, University of Barcelona, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Infectious Diseases, Hospital Universitari de Bellvitge, Bellvitge Institute for Biomedical Research, L'Hospitalet de Llobregat, Red Española de Investigación en Patología Infecciosa, University of Barcelona, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Denholm, Justin T" sort="Denholm, Justin T" uniqKey="Denholm J" first="Justin T" last="Denholm">Justin T. Denholm</name>
<affiliation wicri:level="1"><nlm:affiliation>Victorian Infectious Diseases Service and Department of Microbiology and Immunology, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Victorian Infectious Diseases Service and Department of Microbiology and Immunology, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC</wicri:regionArea>
<wicri:noRegion>VIC</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dominguez, Samuel R" sort="Dominguez, Samuel R" uniqKey="Dominguez S" first="Samuel R" last="Dominguez">Samuel R. Dominguez</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Pediatric Infectious Diseases, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Pediatric Infectious Diseases, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO</wicri:regionArea>
<placeName><region type="state">Colorado</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Duarte, Pericles A D" sort="Duarte, Pericles A D" uniqKey="Duarte P" first="Pericles A D" last="Duarte">Pericles A D. Duarte</name>
<affiliation wicri:level="1"><nlm:affiliation>Universidade Estadual do Oeste do Paraná, Cascavel, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Universidade Estadual do Oeste do Paraná, Cascavel</wicri:regionArea>
<wicri:noRegion>Cascavel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dubnov Raz, Gal" sort="Dubnov Raz, Gal" uniqKey="Dubnov Raz G" first="Gal" last="Dubnov-Raz">Gal Dubnov-Raz</name>
<affiliation wicri:level="1"><nlm:affiliation>The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Ramat Gan</wicri:regionArea>
<wicri:noRegion>Ramat Gan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Echavarria, Marcela" sort="Echavarria, Marcela" uniqKey="Echavarria M" first="Marcela" last="Echavarria">Marcela Echavarria</name>
<affiliation wicri:level="1"><nlm:affiliation>Clinical Virology Laboratory, CEMIC University Hospital, Galvan, Buenos Aires, Argentina.</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>Clinical Virology Laboratory, CEMIC University Hospital, Galvan, Buenos Aires</wicri:regionArea>
<wicri:noRegion>Buenos Aires</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Fanella, Sergio" sort="Fanella, Sergio" uniqKey="Fanella S" first="Sergio" last="Fanella">Sergio Fanella</name>
<affiliation wicri:level="4"><nlm:affiliation>Section of Pediatric Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Section of Pediatric Infectious Diseases, University of Manitoba, Winnipeg, MB</wicri:regionArea>
<orgName type="university">Université du Manitoba</orgName>
<placeName><settlement type="city">Winnipeg</settlement>
<region type="state">Manitoba</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gao, Zhancheng" sort="Gao, Zhancheng" uniqKey="Gao Z" first="Zhancheng" last="Gao">Zhancheng Gao</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gerardin, Patrick" sort="Gerardin, Patrick" uniqKey="Gerardin P" first="Patrick" last="Gérardin">Patrick Gérardin</name>
<affiliation wicri:level="1"><nlm:affiliation>Neonatal Intensive Care Unit/Paediatric Intensive Care Unit, Centre Hospitalier Universitaire-Groupe Hospitalier Sud Réunion, Saint Pierre, Réunion, France; Centre for Clinical Investigation 1410, National Institute for Health and Medical Research/Centre Hospitalier Universitaire/Université de La Réunion, Saint Pierre, Réunion, France; Unité Mixte de Recherche "Processus Infectieux en Milieu Insulaire Tropical" Université de La Réunion/Centre Hospitalier Universitaire/National Institute for Health and Medical Research/Research and Development Institute -Cyclotron Réunion Océan Indien, Saint Denis, Réunion, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Neonatal Intensive Care Unit/Paediatric Intensive Care Unit, Centre Hospitalier Universitaire-Groupe Hospitalier Sud Réunion, Saint Pierre, Réunion, France; Centre for Clinical Investigation 1410, National Institute for Health and Medical Research/Centre Hospitalier Universitaire/Université de La Réunion, Saint Pierre, Réunion, France; Unité Mixte de Recherche "Processus Infectieux en Milieu Insulaire Tropical" Université de La Réunion/Centre Hospitalier Universitaire/National Institute for Health and Medical Research/Research and Development Institute -Cyclotron Réunion Océan Indien, Saint Denis, Réunion</wicri:regionArea>
<wicri:noRegion>Réunion</wicri:noRegion>
<wicri:noRegion>Réunion</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Giannella, Maddalena" sort="Giannella, Maddalena" uniqKey="Giannella M" first="Maddalena" last="Giannella">Maddalena Giannella</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gubbels, Sophie" sort="Gubbels, Sophie" uniqKey="Gubbels S" first="Sophie" last="Gubbels">Sophie Gubbels</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Disease Epidemiology, Sector for National Health Documentation and Research, Statens Serum Institut, Copenhagen, Denmark.</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Department of Infectious Disease Epidemiology, Sector for National Health Documentation and Research, Statens Serum Institut, Copenhagen</wicri:regionArea>
<placeName><settlement type="city">Copenhague</settlement>
<region type="région" nuts="2">Hovedstaden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Herberg, Jethro" sort="Herberg, Jethro" uniqKey="Herberg J" first="Jethro" last="Herberg">Jethro Herberg</name>
<affiliation wicri:level="3"><nlm:affiliation>Section of Paediatrics, Division of Infectious Disease, Imperial College, London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Section of Paediatrics, Division of Infectious Disease, Imperial College, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Iglesias, Anjarath L Higuera" sort="Iglesias, Anjarath L Higuera" uniqKey="Iglesias A" first="Anjarath L Higuera" last="Iglesias">Anjarath L Higuera Iglesias</name>
<affiliation wicri:level="1"><nlm:affiliation>Epidemiology Research Unit, Instituto Nacional de Enfermedades Respiratorias, Ismael Cosío Villegas, Mexico City, Mexico.</nlm:affiliation>
<country xml:lang="fr">Mexique</country>
<wicri:regionArea>Epidemiology Research Unit, Instituto Nacional de Enfermedades Respiratorias, Ismael Cosío Villegas, Mexico City</wicri:regionArea>
<wicri:noRegion>Mexico City</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hoger, Peter H" sort="Hoger, Peter H" uniqKey="Hoger P" first="Peter H" last="Hoger">Peter H. Hoger</name>
<affiliation wicri:level="3"><nlm:affiliation>Catholic Children's Hospital Wilhelmstift, Liliencronstr, Hamburg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Catholic Children's Hospital Wilhelmstift, Liliencronstr, Hamburg</wicri:regionArea>
<placeName><settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hu, Xiaoyun" sort="Hu, Xiaoyun" uniqKey="Hu X" first="Xiaoyun" last="Hu">Xiaoyun Hu</name>
<affiliation wicri:level="3"><nlm:affiliation>Peking Union Medical College Hospital, Beijing, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Peking Union Medical College Hospital, Beijing</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Islam, Quazi T" sort="Islam, Quazi T" uniqKey="Islam Q" first="Quazi T" last="Islam">Quazi T. Islam</name>
<affiliation wicri:level="1"><nlm:affiliation>Dhaka Medical College Hospital, Dhaka, Bangladesh.</nlm:affiliation>
<country xml:lang="fr">Bangladesh</country>
<wicri:regionArea>Dhaka Medical College Hospital, Dhaka</wicri:regionArea>
<wicri:noRegion>Dhaka</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jimenez, Mirela F" sort="Jimenez, Mirela F" uniqKey="Jimenez M" first="Mirela F" last="Jiménez">Mirela F. Jiménez</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Ginecologia e Obstetrícia, Universidade Federal de Ciências da Saúde de Porto Alegre, Preceptora da Residência Médica do Hospital Fêmina, Porto Alegre, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Ginecologia e Obstetrícia, Universidade Federal de Ciências da Saúde de Porto Alegre, Preceptora da Residência Médica do Hospital Fêmina, Porto Alegre</wicri:regionArea>
<placeName><settlement type="city">Porto Alegre</settlement>
<region type="state">Rio Grande do Sul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kandeel, Amr" sort="Kandeel, Amr" uniqKey="Kandeel A" first="Amr" last="Kandeel">Amr Kandeel</name>
<affiliation wicri:level="1"><nlm:affiliation>Ministry of Health in Egypt, Cairo, Egypt.</nlm:affiliation>
<country xml:lang="fr">Égypte</country>
<wicri:regionArea>Ministry of Health in Egypt, Cairo</wicri:regionArea>
<wicri:noRegion>Cairo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Keijzers, Gerben" sort="Keijzers, Gerben" uniqKey="Keijzers G" first="Gerben" last="Keijzers">Gerben Keijzers</name>
<affiliation wicri:level="1"><nlm:affiliation>Gold Coast Hospital, Gold Coast, QLD, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Gold Coast Hospital, Gold Coast, QLD</wicri:regionArea>
<wicri:noRegion>QLD</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Khalili, Hossein" sort="Khalili, Hossein" uniqKey="Khalili H" first="Hossein" last="Khalili">Hossein Khalili</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran</wicri:regionArea>
<wicri:noRegion>Tehran</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Knight, Marian" sort="Knight, Marian" uniqKey="Knight M" first="Marian" last="Knight">Marian Knight</name>
<affiliation wicri:level="4"><nlm:affiliation>National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford</wicri:regionArea>
<placeName><settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
<author><name sortKey="Kudo, Koichiro" sort="Kudo, Koichiro" uniqKey="Kudo K" first="Koichiro" last="Kudo">Koichiro Kudo</name>
<affiliation wicri:level="3"><nlm:affiliation>National Center for Global Health and Medicine, Tokyo, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>National Center for Global Health and Medicine, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
<region type="région">Région de Kantō</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kusznierz, Gabriela" sort="Kusznierz, Gabriela" uniqKey="Kusznierz G" first="Gabriela" last="Kusznierz">Gabriela Kusznierz</name>
<affiliation wicri:level="1"><nlm:affiliation>National Institute of Respiratory Diseases, 'Dr Emilio Coni', Santa Fe, Argentina.</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>National Institute of Respiratory Diseases, 'Dr Emilio Coni', Santa Fe</wicri:regionArea>
<wicri:noRegion>Santa Fe</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kuzman, Ilija" sort="Kuzman, Ilija" uniqKey="Kuzman I" first="Ilija" last="Kuzman">Ilija Kuzman</name>
<affiliation wicri:level="1"><nlm:affiliation>University Hospital for Infectious Diseases, University of Zagreb, School of Medicine, Zagreb, Croatia.</nlm:affiliation>
<country xml:lang="fr">Croatie</country>
<wicri:regionArea>University Hospital for Infectious Diseases, University of Zagreb, School of Medicine, Zagreb</wicri:regionArea>
<wicri:noRegion>Zagreb</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kwan, Arthur M C" sort="Kwan, Arthur M C" uniqKey="Kwan A" first="Arthur M C" last="Kwan">Arthur M C. Kwan</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Intensive Care, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong, Hong Kong.</nlm:affiliation>
<country xml:lang="fr">Hong Kong</country>
<wicri:regionArea>Department of Intensive Care, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong</wicri:regionArea>
<wicri:noRegion>Hong Kong</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Amine, Idriss Lahlou" sort="Amine, Idriss Lahlou" uniqKey="Amine I" first="Idriss Lahlou" last="Amine">Idriss Lahlou Amine</name>
<affiliation wicri:level="3"><nlm:affiliation>University Mohammed V-Souissi, Faculty of Medicine and Pharmacy, Mohammed V Military Teaching Hospital, Biosafety Level 3 and Research Laboratory, Rabat, Morocco.</nlm:affiliation>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea>University Mohammed V-Souissi, Faculty of Medicine and Pharmacy, Mohammed V Military Teaching Hospital, Biosafety Level 3 and Research Laboratory, Rabat</wicri:regionArea>
<placeName><settlement type="city">Rabat</settlement>
<region nuts="2">Rabat-Salé-Kénitra</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Langenegger, Eduard" sort="Langenegger, Eduard" uniqKey="Langenegger E" first="Eduard" last="Langenegger">Eduard Langenegger</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Gynaecology, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>Department of Obstetrics and Gynaecology, Stellenbosch University and Tygerberg Hospital, Cape Town</wicri:regionArea>
<wicri:noRegion>Cape Town</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lankarani, Kamran B" sort="Lankarani, Kamran B" uniqKey="Lankarani K" first="Kamran B" last="Lankarani">Kamran B. Lankarani</name>
<affiliation wicri:level="1"><nlm:affiliation>Health Policy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>Health Policy Research Center, Shiraz University of Medical Sciences, Shiraz</wicri:regionArea>
<wicri:noRegion>Shiraz</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Leo, Yee Sin" sort="Leo, Yee Sin" uniqKey="Leo Y" first="Yee-Sin" last="Leo">Yee-Sin Leo</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.</nlm:affiliation>
<country xml:lang="fr">Singapour</country>
<wicri:regionArea>Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore</wicri:regionArea>
<wicri:noRegion>Singapore</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Linko, Rita" sort="Linko, Rita" uniqKey="Linko R" first="Rita" last="Linko">Rita Linko</name>
<affiliation wicri:level="1"><nlm:affiliation>Helsinki University Hospital, Helsinki, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Helsinki University Hospital, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Liu, Pei" sort="Liu, Pei" uniqKey="Liu P" first="Pei" last="Liu">Pei Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Diseases, the First Affiliated Hospital, China Medical University, Shenyang, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Infectious Diseases, the First Affiliated Hospital, China Medical University, Shenyang</wicri:regionArea>
<wicri:noRegion>Shenyang</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Madanat, Faris" sort="Madanat, Faris" uniqKey="Madanat F" first="Faris" last="Madanat">Faris Madanat</name>
<affiliation wicri:level="1"><nlm:affiliation>King Hussein Cancer Center, Department of Pediatrics, Amman, Jordan.</nlm:affiliation>
<country xml:lang="fr">Jordanie</country>
<wicri:regionArea>King Hussein Cancer Center, Department of Pediatrics, Amman</wicri:regionArea>
<wicri:noRegion>Amman</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mayo Montero, Elga" sort="Mayo Montero, Elga" uniqKey="Mayo Montero E" first="Elga" last="Mayo-Montero">Elga Mayo-Montero</name>
<affiliation wicri:level="3"><nlm:affiliation>Instituto de Medicina Preventiva de la Defensa, Capitan Medico Ramon y Cajal, Ministerio de Defensa, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Instituto de Medicina Preventiva de la Defensa, Capitan Medico Ramon y Cajal, Ministerio de Defensa, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcgeer, Allison" sort="Mcgeer, Allison" uniqKey="Mcgeer A" first="Allison" last="Mcgeer">Allison Mcgeer</name>
<affiliation wicri:level="4"><nlm:affiliation>Toronto Invasive Bacterial Diseases Network, University of Toronto, Toronto, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Toronto Invasive Bacterial Diseases Network, University of Toronto, Toronto, ON</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Memish, Ziad" sort="Memish, Ziad" uniqKey="Memish Z" first="Ziad" last="Memish">Ziad Memish</name>
<affiliation wicri:level="1"><nlm:affiliation>Ministry of Health, Riyadh, Saudi Arabia; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.</nlm:affiliation>
<country xml:lang="fr">Arabie saoudite</country>
<wicri:regionArea>Ministry of Health, Riyadh, Saudi Arabia; College of Medicine, Alfaisal University, Riyadh</wicri:regionArea>
<wicri:noRegion>Riyadh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Metan, Gokhan" sort="Metan, Gokhan" uniqKey="Metan G" first="Gokhan" last="Metan">Gokhan Metan</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Diseases and Clinical Microbiology, Erciyes University Faculty of Medicine, Kayseri, Turkey.</nlm:affiliation>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Department of Infectious Diseases and Clinical Microbiology, Erciyes University Faculty of Medicine, Kayseri</wicri:regionArea>
<wicri:noRegion>Kayseri</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mickiene, Auks" sort="Mickiene, Auks" uniqKey="Mickiene A" first="Auks" last="Mickiene">Auks Mickiene</name>
<affiliation wicri:level="1"><nlm:affiliation>Lithuanian University of Health Sciences, Kaunas, Lithuania.</nlm:affiliation>
<country xml:lang="fr">Lituanie</country>
<wicri:regionArea>Lithuanian University of Health Sciences, Kaunas</wicri:regionArea>
<wicri:noRegion>Kaunas</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Miki, Dragan" sort="Miki, Dragan" uniqKey="Miki D" first="Dragan" last="Miki">Dragan Miki</name>
<affiliation wicri:level="1"><nlm:affiliation>Military Medical Academy, Clinic for Infectious and Tropical Diseases, Belgrade, Serbia.</nlm:affiliation>
<country xml:lang="fr">Serbie</country>
<wicri:regionArea>Military Medical Academy, Clinic for Infectious and Tropical Diseases, Belgrade</wicri:regionArea>
<wicri:noRegion>Belgrade</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mohn, Kristin G I" sort="Mohn, Kristin G I" uniqKey="Mohn K" first="Kristin G I" last="Mohn">Kristin G I. Mohn</name>
<affiliation wicri:level="1"><nlm:affiliation>Section for Infectious Diseases, Medical Department, and Department of Research and Development, Haukeland University Hospital, Bergen, Norway; The Influenza Centre, Department of Clinical Science, University of Bergen, Bergen, Norway.</nlm:affiliation>
<country xml:lang="fr">Norvège</country>
<wicri:regionArea>Section for Infectious Diseases, Medical Department, and Department of Research and Development, Haukeland University Hospital, Bergen, Norway; The Influenza Centre, Department of Clinical Science, University of Bergen, Bergen</wicri:regionArea>
<wicri:noRegion>Bergen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Moradi, Ahmadreza" sort="Moradi, Ahmadreza" uniqKey="Moradi A" first="Ahmadreza" last="Moradi">Ahmadreza Moradi</name>
<affiliation wicri:level="1"><nlm:affiliation>The Division of Ocular Immunology, Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; National Research Institute for Tuberculosis and Lung Disease, Massih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>The Division of Ocular Immunology, Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; National Research Institute for Tuberculosis and Lung Disease, Massih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran</wicri:regionArea>
<wicri:noRegion>Tehran</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nymadawa, Pagbajabyn" sort="Nymadawa, Pagbajabyn" uniqKey="Nymadawa P" first="Pagbajabyn" last="Nymadawa">Pagbajabyn Nymadawa</name>
<affiliation wicri:level="1"><nlm:affiliation>National Influenza Center, National Center of Communicable Diseases, Ministry of Health, Ulaanbaatar, Mongolia.</nlm:affiliation>
<country xml:lang="fr">Mongolie</country>
<wicri:regionArea>National Influenza Center, National Center of Communicable Diseases, Ministry of Health, Ulaanbaatar</wicri:regionArea>
<wicri:noRegion>Ulaanbaatar</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Oliva, Maria E" sort="Oliva, Maria E" uniqKey="Oliva M" first="Maria E" last="Oliva">Maria E. Oliva</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infection Control, Hospital San Martín de Paraná, Entre Ríos, Argentina.</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>Department of Infection Control, Hospital San Martín de Paraná, Entre Ríos</wicri:regionArea>
<wicri:noRegion>Entre Ríos</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ozkan, Mehpare" sort="Ozkan, Mehpare" uniqKey="Ozkan M" first="Mehpare" last="Ozkan">Mehpare Ozkan</name>
<affiliation wicri:level="1"><nlm:affiliation>Dr Sami Ulus Research and Training Hospital of Women's and Children's Health and Diseases, Clinic of Pediatric Neurology, Ankara, Turkey.</nlm:affiliation>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Dr Sami Ulus Research and Training Hospital of Women's and Children's Health and Diseases, Clinic of Pediatric Neurology, Ankara</wicri:regionArea>
<wicri:noRegion>Ankara</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Parekh, Dhruv" sort="Parekh, Dhruv" uniqKey="Parekh D" first="Dhruv" last="Parekh">Dhruv Parekh</name>
<affiliation wicri:level="4"><nlm:affiliation>Critical Care and Pain Perioperative, Critical Care and Trauma Trials Group, School of Clinical and Experimental Medicine, University of Birmingham, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Critical Care and Pain Perioperative, Critical Care and Trauma Trials Group, School of Clinical and Experimental Medicine, University of Birmingham</wicri:regionArea>
<placeName><settlement type="city">Birmingham</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Midlands de l'Ouest</region>
</placeName>
<orgName type="university">Université de Birmingham</orgName>
</affiliation>
</author>
<author><name sortKey="Paul, Mical" sort="Paul, Mical" uniqKey="Paul M" first="Mical" last="Paul">Mical Paul</name>
<affiliation wicri:level="1"><nlm:affiliation>Division of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel.</nlm:affiliation>
<country xml:lang="fr">Israël</country>
<wicri:regionArea>Division of Infectious Diseases, Rambam Health Care Campus, Haifa</wicri:regionArea>
<wicri:noRegion>Haifa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Polack, Fernando P" sort="Polack, Fernando P" uniqKey="Polack F" first="Fernando P" last="Polack">Fernando P. Polack</name>
<affiliation wicri:level="1"><nlm:affiliation>Vanderbilt Vaccine Center, Department of Pediatrics, Vanderbilt University, Nashville, TN, USA; Fundacion INFANT, Buenos Aires, Argentina.</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>Vanderbilt Vaccine Center, Department of Pediatrics, Vanderbilt University, Nashville, TN, USA; Fundacion INFANT, Buenos Aires</wicri:regionArea>
<wicri:noRegion>Buenos Aires</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rath, Barbara A" sort="Rath, Barbara A" uniqKey="Rath B" first="Barbara A" last="Rath">Barbara A. Rath</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Pediatrics, Division of Pneumonology-Immunology, Charité University Medical Center, Berlin, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Pediatrics, Division of Pneumonology-Immunology, Charité University Medical Center, Berlin</wicri:regionArea>
<placeName><region type="land" nuts="3">Berlin</region>
<settlement type="city">Berlin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rodriguez, Alejandro H" sort="Rodriguez, Alejandro H" uniqKey="Rodriguez A" first="Alejandro H" last="Rodríguez">Alejandro H. Rodríguez</name>
<affiliation wicri:level="1"><nlm:affiliation>Hospital Joan XXIII, Critical Care Department, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Ciber De Enfermedades Respiratorias, Tarragona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Hospital Joan XXIII, Critical Care Department, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Ciber De Enfermedades Respiratorias, Tarragona</wicri:regionArea>
<wicri:noRegion>Tarragona</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sarrouf, Elena B" sort="Sarrouf, Elena B" uniqKey="Sarrouf E" first="Elena B" last="Sarrouf">Elena B. Sarrouf</name>
<affiliation wicri:level="1"><nlm:affiliation>Ministerio de Salud de Tucumán, Tucumán, Argentina.</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>Ministerio de Salud de Tucumán, Tucumán</wicri:regionArea>
<wicri:noRegion>Tucumán</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Seale, Anna C" sort="Seale, Anna C" uniqKey="Seale A" first="Anna C" last="Seale">Anna C. Seale</name>
<affiliation wicri:level="1"><nlm:affiliation>Paediatric Intensive Care Unit, Bristol Children's Hospital, Bristol, UK; Bristol Children's Vaccine Centre, School of Clinical Sciences, University of Bristol, Bristol, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Paediatric Intensive Care Unit, Bristol Children's Hospital, Bristol, UK; Bristol Children's Vaccine Centre, School of Clinical Sciences, University of Bristol, Bristol</wicri:regionArea>
<wicri:noRegion>Bristol</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sertogullarindan, Bunyamin" sort="Sertogullarindan, Bunyamin" uniqKey="Sertogullarindan B" first="Bunyamin" last="Sertogullarindan">Bunyamin Sertogullarindan</name>
<affiliation wicri:level="1"><nlm:affiliation>Yuzuncu Yil University Medical Faculty, Department of Pulmonary Medicine, Van, Turkey.</nlm:affiliation>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Yuzuncu Yil University Medical Faculty, Department of Pulmonary Medicine, Van</wicri:regionArea>
<wicri:noRegion>Van</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Siqueira, Marilda M" sort="Siqueira, Marilda M" uniqKey="Siqueira M" first="Marilda M" last="Siqueira">Marilda M. Siqueira</name>
<affiliation wicri:level="3"><nlm:affiliation>Laboratory of Respiratory Viruses, Oswaldo Cruz Institute/Fiocruz, Rio de Janeiro, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Laboratory of Respiratory Viruses, Oswaldo Cruz Institute/Fiocruz, Rio de Janeiro</wicri:regionArea>
<placeName><settlement type="city">Rio de Janeiro</settlement>
<region type="state">État de Rio de Janeiro</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Skr T Magierlo, Joanna" sort="Skr T Magierlo, Joanna" uniqKey="Skr T Magierlo J" first="Joanna" last="Skr T-Magierło">Joanna Skr T-Magierło</name>
<affiliation wicri:level="1"><nlm:affiliation>Uniwersytet Rzeszowski, Rzeszów, Poland.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>Uniwersytet Rzeszowski, Rzeszów</wicri:regionArea>
<wicri:noRegion>Rzeszów</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stephan, Frank" sort="Stephan, Frank" uniqKey="Stephan F" first="Frank" last="Stephan">Frank Stephan</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Emergency Medicine, University Hospital Basel, Basel, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Emergency Medicine, University Hospital Basel, Basel</wicri:regionArea>
<wicri:noRegion>Basel</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Talarek, Ewa" sort="Talarek, Ewa" uniqKey="Talarek E" first="Ewa" last="Talarek">Ewa Talarek</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Children's Infectious Diseases, Medical University of Warsaw, Warsaw, Poland.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>Department of Children's Infectious Diseases, Medical University of Warsaw, Warsaw</wicri:regionArea>
<wicri:noRegion>Warsaw</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tang, Julian W" sort="Tang, Julian W" uniqKey="Tang J" first="Julian W" last="Tang">Julian W. Tang</name>
<affiliation wicri:level="1"><nlm:affiliation>Division of Microbiology, Molecular Diagnostic Centre, Department of Laboratory Medicine National University Hospital, Singapore, Singapore; Alberta Provincial Laboratory for Public Health, University of Alberta Hospital, Edmonton, AB, Canada; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Division of Microbiology, Molecular Diagnostic Centre, Department of Laboratory Medicine National University Hospital, Singapore, Singapore; Alberta Provincial Laboratory for Public Health, University of Alberta Hospital, Edmonton, AB, Canada; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB</wicri:regionArea>
<wicri:noRegion>AB</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="To, Kelvin K W" sort="To, Kelvin K W" uniqKey="To K" first="Kelvin K W" last="To">Kelvin K W. To</name>
<affiliation wicri:level="1"><nlm:affiliation>Carol Yu Centre for Infection and Division of Infectious Diseases, Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong.</nlm:affiliation>
<country xml:lang="fr">Hong Kong</country>
<wicri:regionArea>Carol Yu Centre for Infection and Division of Infectious Diseases, Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea>
<wicri:noRegion>Queen Mary Hospital</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Torres, Antoni" sort="Torres, Antoni" uniqKey="Torres A" first="Antoni" last="Torres">Antoni Torres</name>
<affiliation wicri:level="3"><nlm:affiliation>Hospital Clinic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Ciber De Enfermedades Respiratorias, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Hospital Clinic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Ciber De Enfermedades Respiratorias, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Torun, Selda H" sort="Torun, Selda H" uniqKey="Torun S" first="Selda H" last="Törün">Selda H. Törün</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatric Infectious Diseases, Istanbul Medical Faculty, Istanbul, Turkey.</nlm:affiliation>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Department of Pediatric Infectious Diseases, Istanbul Medical Faculty, Istanbul</wicri:regionArea>
<wicri:noRegion>Istanbul</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tran, Dat" sort="Tran, Dat" uniqKey="Tran D" first="Dat" last="Tran">Dat Tran</name>
<affiliation wicri:level="4"><nlm:affiliation>Division of Infectious Diseases, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Division of Infectious Diseases, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Uyeki, Timothy M" sort="Uyeki, Timothy M" uniqKey="Uyeki T" first="Timothy M" last="Uyeki">Timothy M. Uyeki</name>
<affiliation wicri:level="2"><nlm:affiliation>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Van Zwol, Annelies" sort="Van Zwol, Annelies" uniqKey="Van Zwol A" first="Annelies" last="Van Zwol">Annelies Van Zwol</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Pediatric Intensive Care, VU University Medical Center, Amsterdam, Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Pediatric Intensive Care, VU University Medical Center, Amsterdam</wicri:regionArea>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
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<author><name sortKey="Vaudry, Wendy" sort="Vaudry, Wendy" uniqKey="Vaudry W" first="Wendy" last="Vaudry">Wendy Vaudry</name>
<affiliation wicri:level="1"><nlm:affiliation>Division of Infectious Diseases, Department of Pediatrics, University of Alberta, Stollery Children's Hospital, Edmonton, AB, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Division of Infectious Diseases, Department of Pediatrics, University of Alberta, Stollery Children's Hospital, Edmonton, AB</wicri:regionArea>
<wicri:noRegion>AB</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vidmar, Tjasa" sort="Vidmar, Tjasa" uniqKey="Vidmar T" first="Tjasa" last="Vidmar">Tjasa Vidmar</name>
<affiliation wicri:level="1"><nlm:affiliation>General Hospital Slovenj Gradec, Slovenj Gradec, Slovenia.</nlm:affiliation>
<country xml:lang="fr">Slovénie</country>
<wicri:regionArea>General Hospital Slovenj Gradec, Slovenj Gradec</wicri:regionArea>
<wicri:noRegion>Slovenj Gradec</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Yokota, Renata T C" sort="Yokota, Renata T C" uniqKey="Yokota R" first="Renata T C" last="Yokota">Renata T C. Yokota</name>
<affiliation wicri:level="2"><nlm:affiliation>Departamento de Vigilância Epidemiológica, Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília DF, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Vigilância Epidemiológica, Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília DF</wicri:regionArea>
<placeName><region type="state">District fédéral (Brésil)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zarogoulidis, Paul" sort="Zarogoulidis, Paul" uniqKey="Zarogoulidis P" first="Paul" last="Zarogoulidis">Paul Zarogoulidis</name>
<affiliation wicri:level="1"><nlm:affiliation>Unit of Infectious Diseases, University General Hospital of Alexandroupolis, Democritus University Thrace, Dragana, Greece.</nlm:affiliation>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Unit of Infectious Diseases, University General Hospital of Alexandroupolis, Democritus University Thrace, Dragana</wicri:regionArea>
<wicri:noRegion>Dragana</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nguyen Van Tam, Jonathan S" sort="Nguyen Van Tam, Jonathan S" uniqKey="Nguyen Van Tam J" first="Jonathan S" last="Nguyen-Van-Tam">Jonathan S. Nguyen-Van-Tam</name>
<affiliation wicri:level="4"><nlm:affiliation>Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK. Electronic address: jvt@nottingham.ac.uk.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Division of Epidemiology and Public Health, University of Nottingham, Nottingham</wicri:regionArea>
<orgName type="university">Université de Nottingham</orgName>
<placeName><settlement type="city">Nottingham</settlement>
<region type="nation">Angleterre</region>
<region type="région" nuts="1">Nottinghamshire</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">The Lancet. Respiratory medicine</title>
<idno type="eISSN">2213-2619</idno>
<imprint><date when="2014" type="published">2014</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Antiviral Agents (therapeutic use)</term>
<term>Child</term>
<term>Enzyme Inhibitors (therapeutic use)</term>
<term>Female</term>
<term>Hospitalization</term>
<term>Humans</term>
<term>Influenza A Virus, H1N1 Subtype</term>
<term>Influenza, Human (drug therapy)</term>
<term>Influenza, Human (mortality)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neuraminidase (antagonists & inhibitors)</term>
<term>Oseltamivir (therapeutic use)</term>
<term>Pandemics</term>
<term>Proportional Hazards Models</term>
<term>Treatment Outcome</term>
<term>Young Adult</term>
<term>Zanamivir (therapeutic use)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Antienzymes (usage thérapeutique)</term>
<term>Antiviraux (usage thérapeutique)</term>
<term>Enfant</term>
<term>Femelle</term>
<term>Grippe humaine (mortalité)</term>
<term>Grippe humaine (traitement médicamenteux)</term>
<term>Hospitalisation</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Modèles de hasards proportionnels</term>
<term>Mâle</term>
<term>Oséltamivir (usage thérapeutique)</term>
<term>Pandémies</term>
<term>Résultat thérapeutique</term>
<term>Sialidase (antagonistes et inhibiteurs)</term>
<term>Sous-type H1N1 du virus de la grippe A</term>
<term>Zanamivir (usage thérapeutique)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="antagonists & inhibitors" xml:lang="en"><term>Neuraminidase</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term>
<term>Enzyme Inhibitors</term>
<term>Oseltamivir</term>
<term>Zanamivir</term>
</keywords>
<keywords scheme="MESH" qualifier="antagonistes et inhibiteurs" xml:lang="fr"><term>Sialidase</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antienzymes</term>
<term>Antiviraux</term>
<term>Oséltamivir</term>
<term>Zanamivir</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Child</term>
<term>Female</term>
<term>Hospitalization</term>
<term>Humans</term>
<term>Influenza A Virus, H1N1 Subtype</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Pandemics</term>
<term>Proportional Hazards Models</term>
<term>Treatment Outcome</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Enfant</term>
<term>Femelle</term>
<term>Hospitalisation</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Modèles de hasards proportionnels</term>
<term>Mâle</term>
<term>Pandémies</term>
<term>Résultat thérapeutique</term>
<term>Sous-type H1N1 du virus de la grippe A</term>
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<front><div type="abstract" xml:lang="en">Neuraminidase inhibitors were widely used during the 2009-10 influenza A H1N1 pandemic, but evidence for their effectiveness in reducing mortality is uncertain. We did a meta-analysis of individual participant data to investigate the association between use of neuraminidase inhibitors and mortality in patients admitted to hospital with pandemic influenza A H1N1pdm09 virus infection.</div>
</front>
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