POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA
Identifieur interne : 001980 ( Main/Merge ); précédent : 001979; suivant : 001981POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA
Auteurs : Inge Kühl [Allemagne] ; Maria Miranda [Allemagne] ; Viktor Posse [Suède] ; Dusanka Milenkovic [Allemagne] ; Arnaud Mourier [Allemagne, France] ; Stefan J. Siira [Australie] ; Nina A. Bonekamp [Allemagne] ; Ulla Neumann [Allemagne] ; Aleksandra Filipovska [Australie] ; Paola Loguercio Polosa [Italie] ; Claes M. Gustafsson [Suède] ; Nils-Göran Larsson [Allemagne, Suède]Source :
- Science Advances [ 2375-2548 ] ; 2016.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : DNA, Mitochondrial, DNA-Binding Proteins, DNA-Directed RNA Polymerases, High Mobility Group Proteins.
- genetics : DNA Replication.
- Animals, Gene Expression Regulation, Genome, Mitochondrial, Mice, Transcription, Genetic.
Abstract
Mitochondrial transcription for replication primer formation has priority over gene expression at low POLRMT levels.
Url:
DOI: 10.1126/sciadv.1600963
PubMed: 27532055
PubMed Central: 4975551
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PMC:4975551Le document en format XML
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<term>DNA, Mitochondrial (genetics)</term>
<term>DNA-Binding Proteins (genetics)</term>
<term>DNA-Directed RNA Polymerases (genetics)</term>
<term>Gene Expression Regulation</term>
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<term>Génome mitochondrial</term>
<term>Protéines HMG (génétique)</term>
<term>Protéines de liaison à l'ADN (génétique)</term>
<term>Régulation de l'expression des gènes</term>
<term>Réplication de l'ADN (génétique)</term>
<term>Souris</term>
<term>Transcription génétique</term>
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<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>DNA Replication</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ADN mitochondrial</term>
<term>DNA-directed RNA polymerases</term>
<term>Protéines HMG</term>
<term>Protéines de liaison à l'ADN</term>
<term>Réplication de l'ADN</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Gene Expression Regulation</term>
<term>Genome, Mitochondrial</term>
<term>Mice</term>
<term>Transcription, Genetic</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Génome mitochondrial</term>
<term>Régulation de l'expression des gènes</term>
<term>Souris</term>
<term>Transcription génétique</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Mitochondrial transcription for replication primer formation has priority over gene expression at low POLRMT levels.</p>
</div>
</front>
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<author><name sortKey="Franz, T" uniqKey="Franz T">T. Franz</name>
</author>
<author><name sortKey="Erdjument Nromage, H" uniqKey="Erdjument Nromage H">H. Erdjument-Nromage</name>
</author>
<author><name sortKey="Tempst, P" uniqKey="Tempst P">P. Tempst</name>
</author>
<author><name sortKey="Hallberg, B M" uniqKey="Hallberg B">B. M. Hallberg</name>
</author>
<author><name sortKey="Gustafsson, C M" uniqKey="Gustafsson C">C. M. Gustafsson</name>
</author>
<author><name sortKey="Larsson, N G" uniqKey="Larsson N">N.-G. Larsson</name>
</author>
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