Predictors of response to tenofovir disoproxil fumarate plus peginterferon alfa-2a combination therapy for chronic hepatitis B.
Identifieur interne : 001905 ( Main/Merge ); précédent : 001904; suivant : 001906Predictors of response to tenofovir disoproxil fumarate plus peginterferon alfa-2a combination therapy for chronic hepatitis B.
Auteurs : P. Marcellin [France] ; S H Ahn [Corée du Sud] ; W-L Chuang [Taïwan] ; A J Hui [République populaire de Chine] ; F. Tabak [Turquie] ; R. Mehta [Inde] ; J. Petersen [Allemagne] ; C-M Lee [Taïwan] ; X. Ma [États-Unis] ; F A Caruntu [Roumanie] ; W Y Tak [Corée du Sud] ; M. Elkhashab [Canada] ; L. Lin [États-Unis] ; G. Wu [États-Unis] ; E B Martins [États-Unis] ; P. Charuworn [États-Unis] ; L J Yee [États-Unis] ; S G Lim ; G R Foster [Royaume-Uni] ; S. Fung [Canada] ; L. Morano [Espagne] ; D. Samuel [France] ; K. Agarwal [Royaume-Uni] ; R. Idilman [Turquie] ; S I Strasser [Australie] ; M. Buti [Espagne] ; G B Gaeta [Italie] ; G. Papatheodoridis [Grèce] ; R. Flisiak [Pologne] ; H L Y. Chan [République populaire de Chine]Source :
- Alimentary pharmacology & therapeutics [ 1365-2036 ] ; 2016.
Descripteurs français
- KwdFr :
- ADN viral (sang), Administration par voie orale, Adulte, Adulte d'âge moyen, Antigènes de surface du virus de l'hépatite B (sang), Antiviraux (administration et posologie), Association de médicaments, Femelle, Humains, Hépatite B chronique (diagnostic), Hépatite B chronique (traitement médicamenteux), Injections sous-cutanées, Interféron alpha (administration et posologie), Mâle, Polyéthylène glycols (administration et posologie), Protéines recombinantes (administration et posologie), Résultat thérapeutique, Ténofovir (administration et posologie), Valeur prédictive des tests, Virus de l'hépatite B (), Virus de l'hépatite B (génétique).
- MESH :
- administration et posologie : Antiviraux, Interféron alpha, Polyéthylène glycols, Protéines recombinantes, Ténofovir.
- diagnostic : Hépatite B chronique.
- génétique : Virus de l'hépatite B.
- sang : ADN viral, Antigènes de surface du virus de l'hépatite B.
- traitement médicamenteux : Hépatite B chronique.
- Administration par voie orale, Adulte, Adulte d'âge moyen, Association de médicaments, Femelle, Humains, Injections sous-cutanées, Mâle, Résultat thérapeutique, Valeur prédictive des tests, Virus de l'hépatite B.
English descriptors
- KwdEn :
- Administration, Oral, Adult, Antiviral Agents (administration & dosage), DNA, Viral (blood), Drug Therapy, Combination, Female, Hepatitis B Surface Antigens (blood), Hepatitis B virus (drug effects), Hepatitis B virus (genetics), Hepatitis B, Chronic (diagnosis), Hepatitis B, Chronic (drug therapy), Humans, Injections, Subcutaneous, Interferon-alpha (administration & dosage), Male, Middle Aged, Polyethylene Glycols (administration & dosage), Predictive Value of Tests, Recombinant Proteins (administration & dosage), Tenofovir (administration & dosage), Treatment Outcome.
- MESH :
- chemical , administration & dosage : Antiviral Agents, Interferon-alpha, Polyethylene Glycols, Recombinant Proteins, Tenofovir.
- chemical , blood : DNA, Viral, Hepatitis B Surface Antigens.
- diagnosis : Hepatitis B, Chronic.
- drug effects : Hepatitis B virus.
- drug therapy : Hepatitis B, Chronic.
- genetics : Hepatitis B virus.
- Administration, Oral, Adult, Drug Therapy, Combination, Female, Humans, Injections, Subcutaneous, Male, Middle Aged, Predictive Value of Tests, Treatment Outcome.
Abstract
In patients with chronic hepatitis B, tenofovir disoproxil fumarate (TDF) plus pegylated interferon (PEG-IFN) for 48-weeks results in higher rates of hepatitis B surface antigen (HBsAg) loss than either monotherapy.
DOI: 10.1111/apt.13779
PubMed: 27629859
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pubmed:27629859Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Predictors of response to tenofovir disoproxil fumarate plus peginterferon alfa-2a combination therapy for chronic hepatitis B.</title>
<author><name sortKey="Marcellin, P" sort="Marcellin, P" uniqKey="Marcellin P" first="P" last="Marcellin">P. Marcellin</name>
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<author><name sortKey="Ahn, S H" sort="Ahn, S H" uniqKey="Ahn S" first="S H" last="Ahn">S H Ahn</name>
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<author><name sortKey="Chuang, W L" sort="Chuang, W L" uniqKey="Chuang W" first="W-L" last="Chuang">W-L Chuang</name>
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<author><name sortKey="Hui, A J" sort="Hui, A J" uniqKey="Hui A" first="A J" last="Hui">A J Hui</name>
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<author><name sortKey="Tabak, F" sort="Tabak, F" uniqKey="Tabak F" first="F" last="Tabak">F. Tabak</name>
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<author><name sortKey="Ma, X" sort="Ma, X" uniqKey="Ma X" first="X" last="Ma">X. Ma</name>
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<author><name sortKey="Caruntu, F A" sort="Caruntu, F A" uniqKey="Caruntu F" first="F A" last="Caruntu">F A Caruntu</name>
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<author><name sortKey="Tak, W Y" sort="Tak, W Y" uniqKey="Tak W" first="W Y" last="Tak">W Y Tak</name>
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<author><name sortKey="Elkhashab, M" sort="Elkhashab, M" uniqKey="Elkhashab M" first="M" last="Elkhashab">M. Elkhashab</name>
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<author><name sortKey="Martins, E B" sort="Martins, E B" uniqKey="Martins E" first="E B" last="Martins">E B Martins</name>
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<author><name sortKey="Charuworn, P" sort="Charuworn, P" uniqKey="Charuworn P" first="P" last="Charuworn">P. Charuworn</name>
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<author><name sortKey="Lim, S G" sort="Lim, S G" uniqKey="Lim S" first="S G" last="Lim">S G Lim</name>
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<author><name sortKey="Foster, G R" sort="Foster, G R" uniqKey="Foster G" first="G R" last="Foster">G R Foster</name>
<affiliation wicri:level="1"><nlm:affiliation>London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
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<author><name sortKey="Fung, S" sort="Fung, S" uniqKey="Fung S" first="S" last="Fung">S. Fung</name>
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<country xml:lang="fr">Canada</country>
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<wicri:noRegion>ON</wicri:noRegion>
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<author><name sortKey="Morano, L" sort="Morano, L" uniqKey="Morano L" first="L" last="Morano">L. Morano</name>
<affiliation wicri:level="1"><nlm:affiliation>Pontevedra, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Pontevedra</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Samuel, D" sort="Samuel, D" uniqKey="Samuel D" first="D" last="Samuel">D. Samuel</name>
<affiliation wicri:level="1"><nlm:affiliation>Villejuif, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Villejuif</wicri:regionArea>
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<author><name sortKey="Agarwal, K" sort="Agarwal, K" uniqKey="Agarwal K" first="K" last="Agarwal">K. Agarwal</name>
<affiliation wicri:level="1"><nlm:affiliation>London, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>London</wicri:regionArea>
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<author><name sortKey="Idilman, R" sort="Idilman, R" uniqKey="Idilman R" first="R" last="Idilman">R. Idilman</name>
<affiliation wicri:level="1"><nlm:affiliation>Ankara, Turkey.</nlm:affiliation>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Ankara</wicri:regionArea>
</affiliation>
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<author><name sortKey="Strasser, S I" sort="Strasser, S I" uniqKey="Strasser S" first="S I" last="Strasser">S I Strasser</name>
<affiliation wicri:level="1"><nlm:affiliation>Sydney, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Sydney</wicri:regionArea>
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<author><name sortKey="Buti, M" sort="Buti, M" uniqKey="Buti M" first="M" last="Buti">M. Buti</name>
<affiliation wicri:level="1"><nlm:affiliation>Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Barcelona</wicri:regionArea>
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<author><name sortKey="Gaeta, G B" sort="Gaeta, G B" uniqKey="Gaeta G" first="G B" last="Gaeta">G B Gaeta</name>
<affiliation wicri:level="1"><nlm:affiliation>Naples, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Naples</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Papatheodoridis, G" sort="Papatheodoridis, G" uniqKey="Papatheodoridis G" first="G" last="Papatheodoridis">G. Papatheodoridis</name>
<affiliation wicri:level="1"><nlm:affiliation>Athens, Greece.</nlm:affiliation>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Athens</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Flisiak, R" sort="Flisiak, R" uniqKey="Flisiak R" first="R" last="Flisiak">R. Flisiak</name>
<affiliation wicri:level="1"><nlm:affiliation>Bialystok, Poland.</nlm:affiliation>
<country xml:lang="fr">Pologne</country>
<wicri:regionArea>Bialystok</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Chan, H L Y" sort="Chan, H L Y" uniqKey="Chan H" first="H L Y" last="Chan">H L Y. Chan</name>
<affiliation wicri:level="1"><nlm:affiliation>Hong Kong, China. hlychan@cuhk.edu.hk.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hong Kong</wicri:regionArea>
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<series><title level="j">Alimentary pharmacology & therapeutics</title>
<idno type="eISSN">1365-2036</idno>
<imprint><date when="2016" type="published">2016</date>
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<term>Adult</term>
<term>Antiviral Agents (administration & dosage)</term>
<term>DNA, Viral (blood)</term>
<term>Drug Therapy, Combination</term>
<term>Female</term>
<term>Hepatitis B Surface Antigens (blood)</term>
<term>Hepatitis B virus (drug effects)</term>
<term>Hepatitis B virus (genetics)</term>
<term>Hepatitis B, Chronic (diagnosis)</term>
<term>Hepatitis B, Chronic (drug therapy)</term>
<term>Humans</term>
<term>Injections, Subcutaneous</term>
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<term>Middle Aged</term>
<term>Polyethylene Glycols (administration & dosage)</term>
<term>Predictive Value of Tests</term>
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<term>Adulte d'âge moyen</term>
<term>Antigènes de surface du virus de l'hépatite B (sang)</term>
<term>Antiviraux (administration et posologie)</term>
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<term>Ténofovir</term>
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<front><div type="abstract" xml:lang="en">In patients with chronic hepatitis B, tenofovir disoproxil fumarate (TDF) plus pegylated interferon (PEG-IFN) for 48-weeks results in higher rates of hepatitis B surface antigen (HBsAg) loss than either monotherapy.</div>
</front>
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