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Association of the HLA-B*53:01 Allele With Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome During Treatment of HIV Infection With Raltegravir.

Identifieur interne : 001133 ( Main/Merge ); précédent : 001132; suivant : 001134

Association of the HLA-B*53:01 Allele With Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome During Treatment of HIV Infection With Raltegravir.

Auteurs : Mark Thomas [Nouvelle-Zélande] ; Chris Hopkins [Nouvelle-Zélande] ; Eamon Duffy [Nouvelle-Zélande] ; Daniel Lee [États-Unis] ; Pierre Loulergue [France] ; Diego Ripamonti [Italie] ; David A. Ostrov [États-Unis] ; Elizabeth Phillips [États-Unis]

Source :

RBID : pubmed:28369189

Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare, severe adverse event during treatment with raltegravir. The occurrence of DRESS syndrome during treatment with other drugs is strongly associated with particular HLA alleles.

DOI: 10.1093/cid/cix096
PubMed: 28369189

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pubmed:28369189

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