AustralieFrV1, Main, Exploration, bibRecordById, pubmed:25316307

Sexually dimorphic dopaminergic dysfunction in a transgenic mouse model of Huntington's disease.

Identifieur interne : 003512 ( Main/Exploration ); précédent : 003511; suivant : 003513

Sexually dimorphic dopaminergic dysfunction in a transgenic mouse model of Huntington's disease.

Auteurs : Thibault Renoir [Australie] ; Andrew Argyropoulos [Australie] ; Caroline Chevarin [France] ; Laurence Lanfumey [France] ; Anthony J. Hannan [Australie]

Source :

Pharmacology, biochemistry, and behavior [ 1873-5177 ] ; 2014.

RBID : pubmed:25316307

Descripteurs français

KwdFr :
- Acide 3,4-dihydroxy-benzèneacétique (antagonistes et inhibiteurs), Acide 3,4-dihydroxy-benzèneacétique (métabolisme), Animaux, Caractères sexuels, Dopamine (métabolisme), Femelle, Inhibiteurs de la capture de la dopamine (pharmacologie), Inhibiteurs de la capture de la dopamine (usage thérapeutique), Maladie de Huntington (génétique), Maladie de Huntington (métabolisme), Maladie de Huntington (traitement médicamenteux), Modèles animaux de maladie humaine, Mâle, Récepteur dopamine D1 (antagonistes et inhibiteurs), Récepteur dopamine D1 (métabolisme), Souris, Souris de lignée C57BL, Souris de lignée CBA, Souris transgéniques.
MESH :
- antagonistes et inhibiteurs : Acide 3,4-dihydroxy-benzèneacétique, Récepteur dopamine D1.
- génétique : Maladie de Huntington.
- métabolisme : Acide 3,4-dihydroxy-benzèneacétique, Dopamine, Maladie de Huntington, Récepteur dopamine D1.
- pharmacologie : Inhibiteurs de la capture de la dopamine.
- traitement médicamenteux : Maladie de Huntington.
- usage thérapeutique : Inhibiteurs de la capture de la dopamine.
- Animaux, Caractères sexuels, Femelle, Modèles animaux de maladie humaine, Mâle, Souris, Souris de lignée C57BL, Souris de lignée CBA, Souris transgéniques.

English descriptors

KwdEn :
- 3,4-Dihydroxyphenylacetic Acid (antagonists & inhibitors), 3,4-Dihydroxyphenylacetic Acid (metabolism), Animals, Disease Models, Animal, Dopamine (metabolism), Dopamine Uptake Inhibitors (pharmacology), Dopamine Uptake Inhibitors (therapeutic use), Female, Huntington Disease (drug therapy), Huntington Disease (genetics), Huntington Disease (metabolism), Male, Mice, Mice, Inbred C57BL, Mice, Inbred CBA, Mice, Transgenic, Receptors, Dopamine D1 (antagonists & inhibitors), Receptors, Dopamine D1 (metabolism), Sex Characteristics.
MESH :
- chemical , antagonists & inhibitors : 3,4-Dihydroxyphenylacetic Acid, Receptors, Dopamine D1.
- chemical , metabolism : 3,4-Dihydroxyphenylacetic Acid, Dopamine, Receptors, Dopamine D1.
- chemical , pharmacology : Dopamine Uptake Inhibitors.
- chemical , therapeutic use : Dopamine Uptake Inhibitors.
- drug therapy : Huntington Disease.
- genetics : Huntington Disease.
- metabolism : Huntington Disease.
- Animals, Disease Models, Animal, Female, Male, Mice, Mice, Inbred C57BL, Mice, Inbred CBA, Mice, Transgenic, Sex Characteristics.

Abstract

Using the R6/1 transgenic mouse model of Huntington's disease (HD), we have recently shown that acute administration with the dopamine-norepinephrine reuptake inhibitor bupropion was able to rescue depressive-like behaviours in female HD mice at 12weeks of age.

DOI: 10.1016/j.pbb.2014.10.004
PubMed: 25316307

Affiliations:

Le document en format XML

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<term>Disease Models, Animal</term>
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<front><div type="abstract" xml:lang="en">Using the R6/1 transgenic mouse model of Huntington's disease (HD), we have recently shown that acute administration with the dopamine-norepinephrine reuptake inhibitor bupropion was able to rescue depressive-like behaviours in female HD mice at 12weeks of age.</div>
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Serveur d'exploration sur les relations entre la France et l'Australie

Sexually dimorphic dopaminergic dysfunction in a transgenic mouse model of Huntington's disease.

Sexually dimorphic dopaminergic dysfunction in a transgenic mouse model of Huntington's disease.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur les relations entre la France et l'Australie
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