Development of the neuromuscular junction: Genetic analysis in mice
Identifieur interne : 00CA05 ( Main/Exploration ); précédent : 00CA04; suivant : 00CA06Development of the neuromuscular junction: Genetic analysis in mice
Auteurs : Joshua R. Sanes [États-Unis] ; Elizabeth D. Apel [États-Unis] ; Robert W. Burgess [États-Unis] ; Ronald B. Emerson [États-Unis] ; Guoping Feng [États-Unis] ; Medha Gautam [États-Unis] ; David Glass [États-Unis] ; R. Mark Grady [États-Unis] ; Eric Krejci [France] ; Jeff W. Lichtman [États-Unis] ; Jonathan T. Lu [États-Unis] ; Jean Massoulié [France] ; Jeffrey H. Miner [États-Unis] ; Lisa M. Moscoso [États-Unis] ; Quyen Nguyen [États-Unis] ; Mia Nichol [États-Unis] ; Peter G. Noakes [États-Unis] ; Bruce L. Patton [États-Unis] ; Young-Jin Son [États-Unis] ; George D. Yancopoulos [États-Unis] ; Heather Zhou [États-Unis]Source :
- Journal of Physiology - Paris [ 0928-4257 ] ; 1998.
English descriptors
- KwdEn :
- Acetylcholine receptors, Achr, Achrs, Agrin, Axon, Basal, Basal lamina, Cell biol, Dystrophin, Gautam, Genetic analysis, Heterologous cells, Lamina, Laminin, Merlie, Motor axons, Motor nerve terminals, Muscle agrin, Musk, Mutant, Mutant mice, Myotubes, Nerve terminal, Nerve terminals, Neuromuscular, Neuromuscular development, Neuromuscular junction, Neuromuscular junctions, Neurosci, Postsynaptic, Postsynaptic differentiation, Postsynaptic membrane, Postsynaptic specializations, Rapsyn, Receptor, Sanes, Schwann, Subunit, Synapse, Synaptic, Synaptic basal lamina, Synaptic cleft, Synaptic development, Synaptic sites, Utrophin, acetylcholine receptor, agrin, basal lamina, laminin, synapse formation.
- Teeft :
- Acetylcholine receptors, Achr, Achrs, Agrin, Axon, Basal, Basal lamina, Cell biol, Dystrophin, Gautam, Genetic analysis, Heterologous cells, Lamina, Laminin, Merlie, Motor axons, Motor nerve terminals, Muscle agrin, Musk, Mutant, Mutant mice, Myotubes, Nerve terminal, Nerve terminals, Neuromuscular, Neuromuscular development, Neuromuscular junction, Neuromuscular junctions, Neurosci, Postsynaptic, Postsynaptic differentiation, Postsynaptic membrane, Postsynaptic specializations, Rapsyn, Receptor, Sanes, Schwann, Subunit, Synapse, Synaptic, Synaptic basal lamina, Synaptic cleft, Synaptic development, Synaptic sites, Utrophin.
Abstract
Abstract: Formation of the skeletal neuromuscular junction is a multi-step process that requires communication between the nerve and muscle. Studies in many laboratories have led to identification of factors that seem likely to mediate these interactions. ‘Knock-out’ mice have now been generated with mutations in several genes that encode candidate transsynaptic messengers and components of their effector mechanisms. Using these mice, it is possible to test hypotheses about the control of synaptogenesis. Here, we review our studies on neuromuscular development in mutant mice lacking agrin αCGRP, rapsyn, MuSK, dystrophin, dystrobrevin, utrophin, laminin α5, laminin β2, collagen α3(IV), the acetylcholine receptor ε subunit, the collagenous tail of acetycholinesterase, fibroblast growth factor-5, the neural cell adhesion molecule, and tenascin-C.
Url:
DOI: 10.1016/S0928-4257(98)80004-1
Affiliations:
- France, États-Unis
- Missouri (État), Tennessee, Washington (État), État de New York, Île-de-France
- Paris, Saint-Louis (Missouri)
- École de médecine (Université Washington de Saint-Louis)
Links toward previous steps (curation, corpus...)
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- to stream Istex, to step Curation: 001954
- to stream Istex, to step Checkpoint: 002364
- to stream Main, to step Merge: 00DA42
- to stream Main, to step Curation: 00CA05
Le document en format XML
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Sanes</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Apel, Elizabeth D" sort="Apel, Elizabeth D" uniqKey="Apel E" first="Elizabeth D." last="Apel">Elizabeth D. Apel</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Burgess, Robert W" sort="Burgess, Robert W" uniqKey="Burgess R" first="Robert W." last="Burgess">Robert W. Burgess</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Emerson, Ronald B" sort="Emerson, Ronald B" uniqKey="Emerson R" first="Ronald B." last="Emerson">Ronald B. Emerson</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Feng, Guoping" sort="Feng, Guoping" uniqKey="Feng G" first="Guoping" last="Feng">Guoping Feng</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Gautam, Medha" sort="Gautam, Medha" uniqKey="Gautam M" first="Medha" last="Gautam">Medha Gautam</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation><affiliation wicri:level="2"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>*Present addresses: M. Gautam, Department of Pharmacology, St. Louis University School of Medicine, St. Louis, MO, USA; J. Miner, Department of Medicine, Washington University, USA; P. Noakes, University of Queensland, Brisbane, Australia, Young-Jin Son, Department of Physiology, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Glass, David" sort="Glass, David" uniqKey="Glass D" first="David" last="Glass">David Glass</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Regeneron Pharmaceuticals, Tarrytown, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Grady, R Mark" sort="Grady, R Mark" uniqKey="Grady R" first="R. Mark" last="Grady">R. Mark Grady</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Krejci, Eric" sort="Krejci, Eric" uniqKey="Krejci E" first="Eric" last="Krejci">Eric Krejci</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Neurobiologie Cellulaire et Moléculaire, École Normale Supérieure, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Lichtman, Jeff W" sort="Lichtman, Jeff W" uniqKey="Lichtman J" first="Jeff W." last="Lichtman">Jeff W. Lichtman</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Lu, Jonathan T" sort="Lu, Jonathan T" uniqKey="Lu J" first="Jonathan T." last="Lu">Jonathan T. Lu</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Massoulie, Jean" sort="Massoulie, Jean" uniqKey="Massoulie J" first="Jean" last="Massoulié">Jean Massoulié</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Neurobiologie Cellulaire et Moléculaire, École Normale Supérieure, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Miner, Jeffrey H" sort="Miner, Jeffrey H" uniqKey="Miner J" first="Jeffrey H." last="Miner">Jeffrey H. Miner</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation><affiliation wicri:level="2"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>*Present addresses: M. Gautam, Department of Pharmacology, St. Louis University School of Medicine, St. Louis, MO, USA; J. Miner, Department of Medicine, Washington University, USA; P. Noakes, University of Queensland, Brisbane, Australia, Young-Jin Son, Department of Physiology, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Moscoso, Lisa M" sort="Moscoso, Lisa M" uniqKey="Moscoso L" first="Lisa M." last="Moscoso">Lisa M. Moscoso</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Nguyen, Quyen" sort="Nguyen, Quyen" uniqKey="Nguyen Q" first="Quyen" last="Nguyen">Quyen Nguyen</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Nichol, Mia" sort="Nichol, Mia" uniqKey="Nichol M" first="Mia" last="Nichol">Mia Nichol</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Noakes, Peter G" sort="Noakes, Peter G" uniqKey="Noakes P" first="Peter G." last="Noakes">Peter G. Noakes</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation><affiliation wicri:level="2"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>*Present addresses: M. Gautam, Department of Pharmacology, St. Louis University School of Medicine, St. Louis, MO, USA; J. Miner, Department of Medicine, Washington University, USA; P. Noakes, University of Queensland, Brisbane, Australia, Young-Jin Son, Department of Physiology, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Patton, Bruce L" sort="Patton, Bruce L" uniqKey="Patton B" first="Bruce L." last="Patton">Bruce L. Patton</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Son, Young Jin" sort="Son, Young Jin" uniqKey="Son Y" first="Young-Jin" last="Son">Young-Jin Son</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation><affiliation wicri:level="2"><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>*Present addresses: M. Gautam, Department of Pharmacology, St. Louis University School of Medicine, St. Louis, MO, USA; J. Miner, Department of Medicine, Washington University, USA; P. Noakes, University of Queensland, Brisbane, Australia, Young-Jin Son, Department of Physiology, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Yancopoulos, George D" sort="Yancopoulos, George D" uniqKey="Yancopoulos G" first="George D." last="Yancopoulos">George D. Yancopoulos</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Regeneron Pharmaceuticals, Tarrytown, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Zhou, Heather" sort="Zhou, Heather" uniqKey="Zhou H" first="Heather" last="Zhou">Heather Zhou</name><affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Anatomy, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8108, St. Louis, MO 63110</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Physiology - Paris</title><title level="j" type="abbrev">PHYSIO</title><idno type="ISSN">0928-4257</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1998">1998</date><biblScope unit="volume">92</biblScope><biblScope unit="issue">3–4</biblScope><biblScope unit="page" from="167">167</biblScope><biblScope unit="page" to="172">172</biblScope></imprint><idno type="ISSN">0928-4257</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0928-4257</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acetylcholine receptors</term><term>Achr</term><term>Achrs</term><term>Agrin</term><term>Axon</term><term>Basal</term><term>Basal lamina</term><term>Cell biol</term><term>Dystrophin</term><term>Gautam</term><term>Genetic analysis</term><term>Heterologous cells</term><term>Lamina</term><term>Laminin</term><term>Merlie</term><term>Motor axons</term><term>Motor nerve terminals</term><term>Muscle agrin</term><term>Musk</term><term>Mutant</term><term>Mutant mice</term><term>Myotubes</term><term>Nerve terminal</term><term>Nerve terminals</term><term>Neuromuscular</term><term>Neuromuscular development</term><term>Neuromuscular junction</term><term>Neuromuscular junctions</term><term>Neurosci</term><term>Postsynaptic</term><term>Postsynaptic differentiation</term><term>Postsynaptic membrane</term><term>Postsynaptic specializations</term><term>Rapsyn</term><term>Receptor</term><term>Sanes</term><term>Schwann</term><term>Subunit</term><term>Synapse</term><term>Synaptic</term><term>Synaptic basal lamina</term><term>Synaptic cleft</term><term>Synaptic development</term><term>Synaptic sites</term><term>Utrophin</term><term>acetylcholine receptor</term><term>agrin</term><term>basal lamina</term><term>laminin</term><term>synapse formation</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Acetylcholine receptors</term><term>Achr</term><term>Achrs</term><term>Agrin</term><term>Axon</term><term>Basal</term><term>Basal lamina</term><term>Cell biol</term><term>Dystrophin</term><term>Gautam</term><term>Genetic analysis</term><term>Heterologous cells</term><term>Lamina</term><term>Laminin</term><term>Merlie</term><term>Motor axons</term><term>Motor nerve terminals</term><term>Muscle agrin</term><term>Musk</term><term>Mutant</term><term>Mutant mice</term><term>Myotubes</term><term>Nerve terminal</term><term>Nerve terminals</term><term>Neuromuscular</term><term>Neuromuscular development</term><term>Neuromuscular junction</term><term>Neuromuscular junctions</term><term>Neurosci</term><term>Postsynaptic</term><term>Postsynaptic differentiation</term><term>Postsynaptic membrane</term><term>Postsynaptic specializations</term><term>Rapsyn</term><term>Receptor</term><term>Sanes</term><term>Schwann</term><term>Subunit</term><term>Synapse</term><term>Synaptic</term><term>Synaptic basal lamina</term><term>Synaptic cleft</term><term>Synaptic development</term><term>Synaptic sites</term><term>Utrophin</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Formation of the skeletal neuromuscular junction is a multi-step process that requires communication between the nerve and muscle. Studies in many laboratories have led to identification of factors that seem likely to mediate these interactions. ‘Knock-out’ mice have now been generated with mutations in several genes that encode candidate transsynaptic messengers and components of their effector mechanisms. Using these mice, it is possible to test hypotheses about the control of synaptogenesis. Here, we review our studies on neuromuscular development in mutant mice lacking agrin αCGRP, rapsyn, MuSK, dystrophin, dystrobrevin, utrophin, laminin α5, laminin β2, collagen α3(IV), the acetylcholine receptor ε subunit, the collagenous tail of acetycholinesterase, fibroblast growth factor-5, the neural cell adhesion molecule, and tenascin-C.</div></front></TEI><affiliations><list><country><li>France</li><li>États-Unis</li></country><region><li>Missouri (État)</li><li>Tennessee</li><li>Washington (État)</li><li>État de New York</li><li>Île-de-France</li></region><settlement><li>Paris</li><li>Saint-Louis (Missouri)</li></settlement><orgName><li>École de médecine (Université Washington de Saint-Louis)</li></orgName></list><tree><country name="États-Unis"><region name="Missouri (État)"><name sortKey="Sanes, Joshua R" sort="Sanes, Joshua R" uniqKey="Sanes J" first="Joshua R." last="Sanes">Joshua R. Sanes</name></region><name sortKey="Apel, Elizabeth D" sort="Apel, Elizabeth D" uniqKey="Apel E" first="Elizabeth D." last="Apel">Elizabeth D. Apel</name><name sortKey="Burgess, Robert W" sort="Burgess, Robert W" uniqKey="Burgess R" first="Robert W." last="Burgess">Robert W. Burgess</name><name sortKey="Emerson, Ronald B" sort="Emerson, Ronald B" uniqKey="Emerson R" first="Ronald B." last="Emerson">Ronald B. Emerson</name><name sortKey="Feng, Guoping" sort="Feng, Guoping" uniqKey="Feng G" first="Guoping" last="Feng">Guoping Feng</name><name sortKey="Gautam, Medha" sort="Gautam, Medha" uniqKey="Gautam M" first="Medha" last="Gautam">Medha Gautam</name><name sortKey="Gautam, Medha" sort="Gautam, Medha" uniqKey="Gautam M" first="Medha" last="Gautam">Medha Gautam</name><name sortKey="Glass, David" sort="Glass, David" uniqKey="Glass D" first="David" last="Glass">David Glass</name><name sortKey="Grady, R Mark" sort="Grady, R Mark" uniqKey="Grady R" first="R. Mark" last="Grady">R. Mark Grady</name><name sortKey="Lichtman, Jeff W" sort="Lichtman, Jeff W" uniqKey="Lichtman J" first="Jeff W." last="Lichtman">Jeff W. Lichtman</name><name sortKey="Lu, Jonathan T" sort="Lu, Jonathan T" uniqKey="Lu J" first="Jonathan T." last="Lu">Jonathan T. Lu</name><name sortKey="Miner, Jeffrey H" sort="Miner, Jeffrey H" uniqKey="Miner J" first="Jeffrey H." last="Miner">Jeffrey H. Miner</name><name sortKey="Miner, Jeffrey H" sort="Miner, Jeffrey H" uniqKey="Miner J" first="Jeffrey H." last="Miner">Jeffrey H. Miner</name><name sortKey="Moscoso, Lisa M" sort="Moscoso, Lisa M" uniqKey="Moscoso L" first="Lisa M." last="Moscoso">Lisa M. Moscoso</name><name sortKey="Nguyen, Quyen" sort="Nguyen, Quyen" uniqKey="Nguyen Q" first="Quyen" last="Nguyen">Quyen Nguyen</name><name sortKey="Nichol, Mia" sort="Nichol, Mia" uniqKey="Nichol M" first="Mia" last="Nichol">Mia Nichol</name><name sortKey="Noakes, Peter G" sort="Noakes, Peter G" uniqKey="Noakes P" first="Peter G." last="Noakes">Peter G. Noakes</name><name sortKey="Noakes, Peter G" sort="Noakes, Peter G" uniqKey="Noakes P" first="Peter G." last="Noakes">Peter G. Noakes</name><name sortKey="Patton, Bruce L" sort="Patton, Bruce L" uniqKey="Patton B" first="Bruce L." last="Patton">Bruce L. Patton</name><name sortKey="Son, Young Jin" sort="Son, Young Jin" uniqKey="Son Y" first="Young-Jin" last="Son">Young-Jin Son</name><name sortKey="Son, Young Jin" sort="Son, Young Jin" uniqKey="Son Y" first="Young-Jin" last="Son">Young-Jin Son</name><name sortKey="Yancopoulos, George D" sort="Yancopoulos, George D" uniqKey="Yancopoulos G" first="George D." last="Yancopoulos">George D. Yancopoulos</name><name sortKey="Zhou, Heather" sort="Zhou, Heather" uniqKey="Zhou H" first="Heather" last="Zhou">Heather Zhou</name></country><country name="France"><region name="Île-de-France"><name sortKey="Krejci, Eric" sort="Krejci, Eric" uniqKey="Krejci E" first="Eric" last="Krejci">Eric Krejci</name></region><name sortKey="Massoulie, Jean" sort="Massoulie, Jean" uniqKey="Massoulie J" first="Jean" last="Massoulié">Jean Massoulié</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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