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Comparison of in vivo acute stent recoil between the bioresorbable everolimus‐eluting coronary scaffolds (revision 1.0 and 1.1) and the metallic everolimus‐eluting stent

Identifieur interne : 006469 ( Main/Exploration ); précédent : 006468; suivant : 006470

Comparison of in vivo acute stent recoil between the bioresorbable everolimus‐eluting coronary scaffolds (revision 1.0 and 1.1) and the metallic everolimus‐eluting stent

Auteurs : Yoshinobu Onuma [Pays-Bas] ; Patrick W. Serruys [Pays-Bas] ; Josep Gomez [Pays-Bas] ; Bernard De Bruyne [Belgique] ; Dariusz Dudek [Pologne] ; Leif Thuesen [Danemark] ; Peter Smits [Pays-Bas] ; Bernard Chevalier [France] ; Dougal Mcclean [Nouvelle-Zélande] ; Jacques Koolen [Pays-Bas] ; Stephan Windecker [Suisse] ; Robert Whitbourn [Australie] ; Ian Meredith [Australie] ; Hector Garcia-Garcia [Pays-Bas] ; John A. Ormiston [Nouvelle-Zélande]

Source :

RBID : ISTEX:3C1351DDAF9E7D38FB581C599C675CEFB4914BEF

English descriptors

Abstract

Objectives: The ABSORB cohort A trial using the bioresorbable everolimus‐eluting scaffold (BVS revision 1.0, Abbott Vascular) demonstrated a slightly higher acute recoil with BVS than with metallic stents. To reinforce the mechanical strength of the scaffold, the new BVS scaffold (revision 1.1) with modified strut design was developed and tested in the ABSORB cohort B trial. This study sought to evaluate and compare the in vivo acute scaffold recoil of the BVS revision 1.0 in ABSORB cohort A and the BVS revision 1.1 in ABSORB cohort B with the historical recoil of the XIENCE V® everolimus‐eluting metal stent (EES, SPIRIT I and II). Methods: In the ABSORB cohort B trial, 101 patients with one or two de‐novo lesions were enrolled at 10 sites. In ABSORB cohort A, 27 patients treated with a BVS 1.0 were analyzed and compared with EES. Acute absolute recoil, assessed by quantitative coronary angiography, was defined as the difference between mean diameter of the last inflated balloon at the highest pressure (X) and mean lumen diameter of the stent immediately after the last balloon deflation (Y). Acute percent recoil was defined as (X ‐ Y)/X and expressed as a percentage. Results: Out of 101 patients enrolled in the ABSORB cohort B trial, 88 patients are available for complete analysis of acute recoil. Absolute recoil of BVS 1.1 (0.19 ± 0.18 mm) was numerically higher than metallic EES (vs. 0.13 ± 0.21 mm) and similar to BVS 1.0 (0.20 ± 0.21 mm) but the differences did not reach statistical significance (P = 0.40). The acute percent recoil demonstrated the same trend (EES: 4.3% ± 7.1%, BVS 1.0: 6.9% ± 7.0%, BVS 1.1: 6.7% ± 6.4%, P = 0.22). In the multivariate regression model, high balloon/artery ratio (>1.1) (OR 1.91 [1.34–2.71]) was the predictive for high absolute recoil (>0.27 mm) while (larger) preprocedural MLD was protective (OR 0.84 [0.72–0.99]). The stent/scaffold type was not a predictor of acute recoil. Conclusions: The average in vivo acute scaffold recoil of the BVS 1.1 is slightly higher than the metallic EES. However, the scaffold/stent type was not predictive of high acute recoil, while implantation in undersized vessels or usage of oversized devices might confound the results. © 2011 Wiley‐Liss, Inc.

Url:
DOI: 10.1002/ccd.22864


Affiliations:


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Le document en format XML

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<term>Absolute recoil</term>
<term>Acute percent recoil</term>
<term>Acute recoil</term>
<term>Acute stent recoil</term>
<term>Angiographic</term>
<term>Angiography</term>
<term>Antiproliferative drug everolimus</term>
<term>Artery lesions</term>
<term>Balloon</term>
<term>Balloon diameter</term>
<term>Ballooning</term>
<term>Bioresorbable scaffold</term>
<term>Black lines</term>
<term>Cardiovascular</term>
<term>Cardiovascular angiography</term>
<term>Cardiovascular interventions</term>
<term>Catheterization</term>
<term>Cine frame</term>
<term>Cohort</term>
<term>Complete analysis</term>
<term>Complete expansion</term>
<term>Coronary arteries</term>
<term>Current analysis</term>
<term>Delivery balloon</term>
<term>Design changes</term>
<term>Drug transfer</term>
<term>High balloon</term>
<term>High ratio</term>
<term>Highest pressure</term>
<term>Implantation</term>
<term>Interquartile range</term>
<term>Ivus</term>
<term>Largest balloon</term>
<term>Last balloon</term>
<term>Late recoil</term>
<term>Lesion</term>
<term>Lower panel</term>
<term>Lumen diameter</term>
<term>Luminal</term>
<term>Luminal diameter</term>
<term>Maximum pressure</term>
<term>Median</term>
<term>Metallic stent</term>
<term>Metallic stents</term>
<term>Minimal luminal diameter</term>
<term>More uniform strut distribution</term>
<term>Multivariate model</term>
<term>Myocardial infarction</term>
<term>Online issue</term>
<term>Onuma</term>
<term>Polymer backbone</term>
<term>Postdilatation</term>
<term>Postdilatation balloon</term>
<term>Postdilated segment</term>
<term>Predictive factors</term>
<term>Preprocedural</term>
<term>Preprocedural ivus imaging</term>
<term>Preprocedural reference diameter</term>
<term>Proper vessel sizing</term>
<term>Radial strength</term>
<term>Recoil</term>
<term>Reference diameter</term>
<term>Reference vessel diameter</term>
<term>Restenotic lesions</term>
<term>Right panel</term>
<term>Same angiographic projection</term>
<term>Same trend</term>
<term>Santa clara</term>
<term>Scaffold</term>
<term>Scaffold recoil</term>
<term>Scaffolding device</term>
<term>Scai</term>
<term>Serruys</term>
<term>Standard deviation</term>
<term>Stent</term>
<term>Stent expansion</term>
<term>Stent recoil</term>
<term>Stent system</term>
<term>Strut</term>
<term>Total population</term>
<term>Uniform vessel wall support</term>
<term>Univariate analysis</term>
<term>Vessel dimensions</term>
<term>Visual assessment</term>
<term>Vivo evaluation</term>
<term>Zigzag hoops</term>
</keywords>
<keywords scheme="Teeft" xml:lang="en">
<term>Absolute recoil</term>
<term>Acute percent recoil</term>
<term>Acute recoil</term>
<term>Acute stent recoil</term>
<term>Angiographic</term>
<term>Angiography</term>
<term>Antiproliferative drug everolimus</term>
<term>Artery lesions</term>
<term>Balloon</term>
<term>Balloon diameter</term>
<term>Ballooning</term>
<term>Bioresorbable scaffold</term>
<term>Black lines</term>
<term>Cardiovascular</term>
<term>Cardiovascular angiography</term>
<term>Cardiovascular interventions</term>
<term>Catheterization</term>
<term>Cine frame</term>
<term>Cohort</term>
<term>Complete analysis</term>
<term>Complete expansion</term>
<term>Coronary arteries</term>
<term>Current analysis</term>
<term>Delivery balloon</term>
<term>Design changes</term>
<term>Drug transfer</term>
<term>High balloon</term>
<term>High ratio</term>
<term>Highest pressure</term>
<term>Implantation</term>
<term>Interquartile range</term>
<term>Ivus</term>
<term>Largest balloon</term>
<term>Last balloon</term>
<term>Late recoil</term>
<term>Lesion</term>
<term>Lower panel</term>
<term>Lumen diameter</term>
<term>Luminal</term>
<term>Luminal diameter</term>
<term>Maximum pressure</term>
<term>Median</term>
<term>Metallic stent</term>
<term>Metallic stents</term>
<term>Minimal luminal diameter</term>
<term>More uniform strut distribution</term>
<term>Multivariate model</term>
<term>Myocardial infarction</term>
<term>Online issue</term>
<term>Onuma</term>
<term>Polymer backbone</term>
<term>Postdilatation</term>
<term>Postdilatation balloon</term>
<term>Postdilated segment</term>
<term>Predictive factors</term>
<term>Preprocedural</term>
<term>Preprocedural ivus imaging</term>
<term>Preprocedural reference diameter</term>
<term>Proper vessel sizing</term>
<term>Radial strength</term>
<term>Recoil</term>
<term>Reference diameter</term>
<term>Reference vessel diameter</term>
<term>Restenotic lesions</term>
<term>Right panel</term>
<term>Same angiographic projection</term>
<term>Same trend</term>
<term>Santa clara</term>
<term>Scaffold</term>
<term>Scaffold recoil</term>
<term>Scaffolding device</term>
<term>Scai</term>
<term>Serruys</term>
<term>Standard deviation</term>
<term>Stent</term>
<term>Stent expansion</term>
<term>Stent recoil</term>
<term>Stent system</term>
<term>Strut</term>
<term>Total population</term>
<term>Uniform vessel wall support</term>
<term>Univariate analysis</term>
<term>Vessel dimensions</term>
<term>Visual assessment</term>
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<front>
<div type="abstract" xml:lang="en">Objectives: The ABSORB cohort A trial using the bioresorbable everolimus‐eluting scaffold (BVS revision 1.0, Abbott Vascular) demonstrated a slightly higher acute recoil with BVS than with metallic stents. To reinforce the mechanical strength of the scaffold, the new BVS scaffold (revision 1.1) with modified strut design was developed and tested in the ABSORB cohort B trial. This study sought to evaluate and compare the in vivo acute scaffold recoil of the BVS revision 1.0 in ABSORB cohort A and the BVS revision 1.1 in ABSORB cohort B with the historical recoil of the XIENCE V® everolimus‐eluting metal stent (EES, SPIRIT I and II). Methods: In the ABSORB cohort B trial, 101 patients with one or two de‐novo lesions were enrolled at 10 sites. In ABSORB cohort A, 27 patients treated with a BVS 1.0 were analyzed and compared with EES. Acute absolute recoil, assessed by quantitative coronary angiography, was defined as the difference between mean diameter of the last inflated balloon at the highest pressure (X) and mean lumen diameter of the stent immediately after the last balloon deflation (Y). Acute percent recoil was defined as (X ‐ Y)/X and expressed as a percentage. Results: Out of 101 patients enrolled in the ABSORB cohort B trial, 88 patients are available for complete analysis of acute recoil. Absolute recoil of BVS 1.1 (0.19 ± 0.18 mm) was numerically higher than metallic EES (vs. 0.13 ± 0.21 mm) and similar to BVS 1.0 (0.20 ± 0.21 mm) but the differences did not reach statistical significance (P = 0.40). The acute percent recoil demonstrated the same trend (EES: 4.3% ± 7.1%, BVS 1.0: 6.9% ± 7.0%, BVS 1.1: 6.7% ± 6.4%, P = 0.22). In the multivariate regression model, high balloon/artery ratio (>1.1) (OR 1.91 [1.34–2.71]) was the predictive for high absolute recoil (>0.27 mm) while (larger) preprocedural MLD was protective (OR 0.84 [0.72–0.99]). The stent/scaffold type was not a predictor of acute recoil. Conclusions: The average in vivo acute scaffold recoil of the BVS 1.1 is slightly higher than the metallic EES. However, the scaffold/stent type was not predictive of high acute recoil, while implantation in undersized vessels or usage of oversized devices might confound the results. © 2011 Wiley‐Liss, Inc.</div>
</front>
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<li>Australie</li>
<li>Belgique</li>
<li>Danemark</li>
<li>France</li>
<li>Nouvelle-Zélande</li>
<li>Pays-Bas</li>
<li>Pologne</li>
<li>Suisse</li>
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<li>Canton de Berne</li>
<li>Hollande-Méridionale</li>
<li>Victoria (État)</li>
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<li>Melbourne</li>
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<name sortKey="Garcia Arcia, Hector" sort="Garcia Arcia, Hector" uniqKey="Garcia Arcia H" first="Hector" last="Garcia-Garcia">Hector Garcia-Garcia</name>
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<name sortKey="Koolen, Jacques" sort="Koolen, Jacques" uniqKey="Koolen J" first="Jacques" last="Koolen">Jacques Koolen</name>
<name sortKey="Serruys, Patrick W" sort="Serruys, Patrick W" uniqKey="Serruys P" first="Patrick W." last="Serruys">Patrick W. Serruys</name>
<name sortKey="Serruys, Patrick W" sort="Serruys, Patrick W" uniqKey="Serruys P" first="Patrick W." last="Serruys">Patrick W. Serruys</name>
<name sortKey="Serruys, Patrick W" sort="Serruys, Patrick W" uniqKey="Serruys P" first="Patrick W." last="Serruys">Patrick W. Serruys</name>
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<name sortKey="De Bruyne, Bernard" sort="De Bruyne, Bernard" uniqKey="De Bruyne B" first="Bernard" last="De Bruyne">Bernard De Bruyne</name>
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<country name="Pologne">
<noRegion>
<name sortKey="Dudek, Dariusz" sort="Dudek, Dariusz" uniqKey="Dudek D" first="Dariusz" last="Dudek">Dariusz Dudek</name>
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</country>
<country name="Danemark">
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<country name="France">
<noRegion>
<name sortKey="Chevalier, Bernard" sort="Chevalier, Bernard" uniqKey="Chevalier B" first="Bernard" last="Chevalier">Bernard Chevalier</name>
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<name sortKey="Mcclean, Dougal" sort="Mcclean, Dougal" uniqKey="Mcclean D" first="Dougal" last="Mcclean">Dougal Mcclean</name>
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<name sortKey="Ormiston, John A" sort="Ormiston, John A" uniqKey="Ormiston J" first="John A." last="Ormiston">John A. Ormiston</name>
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<country name="Suisse">
<region name="Canton de Berne">
<name sortKey="Windecker, Stephan" sort="Windecker, Stephan" uniqKey="Windecker S" first="Stephan" last="Windecker">Stephan Windecker</name>
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<country name="Australie">
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<name sortKey="Meredith, Ian" sort="Meredith, Ian" uniqKey="Meredith I" first="Ian" last="Meredith">Ian Meredith</name>
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</tree>
</affiliations>
</record>

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