AustralieFrV1, Main, Exploration, bibRecord, 004C97

Response assessment in Waldenström macroglobulinaemia: update from the Vlth International Workshop

Identifieur interne : 004C97 ( Main/Exploration ); précédent : 004C96; suivant : 004C98

Response assessment in Waldenström macroglobulinaemia: update from the Vlth International Workshop

Auteurs : Roger G. Owen [Royaume-Uni] ; Robert A. Kyle [États-Unis] ; Marvin J. Stone [États-Unis] ; Andy C. Rawstron [Royaume-Uni] ; Veronique Leblond [France] ; Giampaolo Merlini [Italie] ; Ramon Garcia-Sanz [Espagne] ; Enrique M. Ocio [Espagne] ; Enrica Morra [Italie] ; Pierre Morel [France] ; Kenneth C. Anderson [États-Unis] ; Christopher J. Patterson [États-Unis] ; Nikhil C. Munshi [États-Unis] ; Alessandra Tedeschi [Italie] ; Douglas E. Joshua [Australie] ; Efstathios Kastritis [Grèce] ; Evangelos Terpos [Grèce] ; Irene M. Ghobrial [États-Unis] ; Xavier Leleu [France] ; Morie A. Gertz [États-Unis] ; Stephen M. Ansell [États-Unis] ; William G. Morice [États-Unis] ; Eva Kimby [Suède] ; Steven P. Treon [États-Unis]

Source :

British journal of haematology [ 0007-1048 ] ; 2013.

RBID : Pascal:13-0114668

Descripteurs français

Pascal (Inist)
- Macroglobulinémie de Waldenström, International, Atelier, Maladie résiduelle, Essai clinique, Cancérologie, Hématologie.

English descriptors

KwdEn :
- Cancerology, Clinical trial, Hematology, International, Minimal residual disease, Waldenström macroglobulinemia, Workshop.

Abstract

This report represents a further update of the consensus panel criteria for the assessment of clinical response in patients with Waldenström macroglobulinaemia (WM). These criteria have been updated in light of further data demonstrating an improvement in categorical responses with new drug regimens as well as acknowledgement of the fact that such responses are predictive of overall outcome. A number of key changes are proposed but challenges do however remain and these include the variability in kinetics of immunoglobulin M (IgM) reduction with different treatment modalities and the apparent discrepancy between IgM and bone marrow/ tissue response noted with some regimens. Planned sequential bone marrow assessments are encouraged in clinical trials.

Affiliations:

Australie, Espagne, France, Grèce, Italie, Royaume-Uni, Suède, États-Unis
Attique (région), Hauts-de-France, Lombardie, Nord-Pas-de-Calais, Svealand, Île-de-France
Athènes, Lens (Pas-de-Calais), Lille, Milan, Paris, Stockholm

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000B71
to stream PascalFrancis, to step Curation: 005294
to stream PascalFrancis, to step Checkpoint: 000668
to stream Main, to step Merge: 004E42
to stream Main, to step Curation: 004C97

Le document en format XML

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<author><name sortKey="Morel, Pierre" sort="Morel, Pierre" uniqKey="Morel P" first="Pierre" last="Morel">Pierre Morel</name>
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<country>France</country>
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<settlement type="city">Lens (Pas-de-Calais)</settlement>
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<author><name sortKey="Anderson, Kenneth C" sort="Anderson, Kenneth C" uniqKey="Anderson K" first="Kenneth C." last="Anderson">Kenneth C. Anderson</name>
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</author>
<author><name sortKey="Patterson, Christopher J" sort="Patterson, Christopher J" uniqKey="Patterson C" first="Christopher J." last="Patterson">Christopher J. Patterson</name>
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<author><name sortKey="Munshi, Nikhil C" sort="Munshi, Nikhil C" uniqKey="Munshi N" first="Nikhil C." last="Munshi">Nikhil C. Munshi</name>
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<country>États-Unis</country>
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<author><name sortKey="Tedeschi, Alessandra" sort="Tedeschi, Alessandra" uniqKey="Tedeschi A" first="Alessandra" last="Tedeschi">Alessandra Tedeschi</name>
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<country>Italie</country>
<placeName><settlement type="city">Milan</settlement>
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</author>
<author><name sortKey="Joshua, Douglas E" sort="Joshua, Douglas E" uniqKey="Joshua D" first="Douglas E." last="Joshua">Douglas E. Joshua</name>
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<sZ>15 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Royal Prince Alfred Hospital</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kastritis, Efstathios" sort="Kastritis, Efstathios" uniqKey="Kastritis E" first="Efstathios" last="Kastritis">Efstathios Kastritis</name>
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<country>Grèce</country>
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</affiliation>
</author>
<author><name sortKey="Terpos, Evangelos" sort="Terpos, Evangelos" uniqKey="Terpos E" first="Evangelos" last="Terpos">Evangelos Terpos</name>
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</author>
<author><name sortKey="Ghobrial, Irene M" sort="Ghobrial, Irene M" uniqKey="Ghobrial I" first="Irene M." last="Ghobrial">Irene M. Ghobrial</name>
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<country>États-Unis</country>
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<author><name sortKey="Leleu, Xavier" sort="Leleu, Xavier" uniqKey="Leleu X" first="Xavier" last="Leleu">Xavier Leleu</name>
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<country>France</country>
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<settlement type="city">Lille</settlement>
</placeName>
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</author>
<author><name sortKey="Gertz, Morie A" sort="Gertz, Morie A" uniqKey="Gertz M" first="Morie A." last="Gertz">Morie A. Gertz</name>
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<author><name sortKey="Ansell, Stephen M" sort="Ansell, Stephen M" uniqKey="Ansell S" first="Stephen M." last="Ansell">Stephen M. Ansell</name>
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<wicri:noRegion>Mayo School of Medicine</wicri:noRegion>
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<author><name sortKey="Morice, William G" sort="Morice, William G" uniqKey="Morice W" first="William G." last="Morice">William G. Morice</name>
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<author><name sortKey="Kimby, Eva" sort="Kimby, Eva" uniqKey="Kimby E" first="Eva" last="Kimby">Eva Kimby</name>
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<s2>Stockholm</s2>
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<country>Suède</country>
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</author>
<author><name sortKey="Treon, Steven P" sort="Treon, Steven P" uniqKey="Treon S" first="Steven P." last="Treon">Steven P. Treon</name>
<affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Dana Farber Cancer Institute, Harvard Medical School</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>11 aut.</sZ>
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<sZ>13 aut.</sZ>
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<country>États-Unis</country>
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</analytic>
<series><title level="j" type="main">British journal of haematology</title>
<title level="j" type="abbreviated">Br. j. haematol.</title>
<idno type="ISSN">0007-1048</idno>
<imprint><date when="2013">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">British journal of haematology</title>
<title level="j" type="abbreviated">Br. j. haematol.</title>
<idno type="ISSN">0007-1048</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cancerology</term>
<term>Clinical trial</term>
<term>Hematology</term>
<term>International</term>
<term>Minimal residual disease</term>
<term>Waldenström macroglobulinemia</term>
<term>Workshop</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Macroglobulinémie de Waldenström</term>
<term>International</term>
<term>Atelier</term>
<term>Maladie résiduelle</term>
<term>Essai clinique</term>
<term>Cancérologie</term>
<term>Hématologie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">This report represents a further update of the consensus panel criteria for the assessment of clinical response in patients with Waldenström macroglobulinaemia (WM). These criteria have been updated in light of further data demonstrating an improvement in categorical responses with new drug regimens as well as acknowledgement of the fact that such responses are predictive of overall outcome. A number of key changes are proposed but challenges do however remain and these include the variability in kinetics of immunoglobulin M (IgM) reduction with different treatment modalities and the apparent discrepancy between IgM and bone marrow/ tissue response noted with some regimens. Planned sequential bone marrow assessments are encouraged in clinical trials.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>Espagne</li>
<li>France</li>
<li>Grèce</li>
<li>Italie</li>
<li>Royaume-Uni</li>
<li>Suède</li>
<li>États-Unis</li>
</country>
<region><li>Attique (région)</li>
<li>Hauts-de-France</li>
<li>Lombardie</li>
<li>Nord-Pas-de-Calais</li>
<li>Svealand</li>
<li>Île-de-France</li>
</region>
<settlement><li>Athènes</li>
<li>Lens (Pas-de-Calais)</li>
<li>Lille</li>
<li>Milan</li>
<li>Paris</li>
<li>Stockholm</li>
</settlement>
</list>
<tree><country name="Royaume-Uni"><noRegion><name sortKey="Owen, Roger G" sort="Owen, Roger G" uniqKey="Owen R" first="Roger G." last="Owen">Roger G. Owen</name>
</noRegion>
<name sortKey="Rawstron, Andy C" sort="Rawstron, Andy C" uniqKey="Rawstron A" first="Andy C." last="Rawstron">Andy C. Rawstron</name>
</country>
<country name="États-Unis"><noRegion><name sortKey="Kyle, Robert A" sort="Kyle, Robert A" uniqKey="Kyle R" first="Robert A." last="Kyle">Robert A. Kyle</name>
</noRegion>
<name sortKey="Anderson, Kenneth C" sort="Anderson, Kenneth C" uniqKey="Anderson K" first="Kenneth C." last="Anderson">Kenneth C. Anderson</name>
<name sortKey="Ansell, Stephen M" sort="Ansell, Stephen M" uniqKey="Ansell S" first="Stephen M." last="Ansell">Stephen M. Ansell</name>
<name sortKey="Gertz, Morie A" sort="Gertz, Morie A" uniqKey="Gertz M" first="Morie A." last="Gertz">Morie A. Gertz</name>
<name sortKey="Ghobrial, Irene M" sort="Ghobrial, Irene M" uniqKey="Ghobrial I" first="Irene M." last="Ghobrial">Irene M. Ghobrial</name>
<name sortKey="Morice, William G" sort="Morice, William G" uniqKey="Morice W" first="William G." last="Morice">William G. Morice</name>
<name sortKey="Munshi, Nikhil C" sort="Munshi, Nikhil C" uniqKey="Munshi N" first="Nikhil C." last="Munshi">Nikhil C. Munshi</name>
<name sortKey="Patterson, Christopher J" sort="Patterson, Christopher J" uniqKey="Patterson C" first="Christopher J." last="Patterson">Christopher J. Patterson</name>
<name sortKey="Stone, Marvin J" sort="Stone, Marvin J" uniqKey="Stone M" first="Marvin J." last="Stone">Marvin J. Stone</name>
<name sortKey="Treon, Steven P" sort="Treon, Steven P" uniqKey="Treon S" first="Steven P." last="Treon">Steven P. Treon</name>
</country>
<country name="France"><region name="Île-de-France"><name sortKey="Leblond, Veronique" sort="Leblond, Veronique" uniqKey="Leblond V" first="Veronique" last="Leblond">Veronique Leblond</name>
</region>
<name sortKey="Leleu, Xavier" sort="Leleu, Xavier" uniqKey="Leleu X" first="Xavier" last="Leleu">Xavier Leleu</name>
<name sortKey="Morel, Pierre" sort="Morel, Pierre" uniqKey="Morel P" first="Pierre" last="Morel">Pierre Morel</name>
</country>
<country name="Italie"><noRegion><name sortKey="Merlini, Giampaolo" sort="Merlini, Giampaolo" uniqKey="Merlini G" first="Giampaolo" last="Merlini">Giampaolo Merlini</name>
</noRegion>
<name sortKey="Morra, Enrica" sort="Morra, Enrica" uniqKey="Morra E" first="Enrica" last="Morra">Enrica Morra</name>
<name sortKey="Tedeschi, Alessandra" sort="Tedeschi, Alessandra" uniqKey="Tedeschi A" first="Alessandra" last="Tedeschi">Alessandra Tedeschi</name>
</country>
<country name="Espagne"><noRegion><name sortKey="Garcia Sanz, Ramon" sort="Garcia Sanz, Ramon" uniqKey="Garcia Sanz R" first="Ramon" last="Garcia-Sanz">Ramon Garcia-Sanz</name>
</noRegion>
<name sortKey="Ocio, Enrique M" sort="Ocio, Enrique M" uniqKey="Ocio E" first="Enrique M." last="Ocio">Enrique M. Ocio</name>
</country>
<country name="Australie"><noRegion><name sortKey="Joshua, Douglas E" sort="Joshua, Douglas E" uniqKey="Joshua D" first="Douglas E." last="Joshua">Douglas E. Joshua</name>
</noRegion>
</country>
<country name="Grèce"><region name="Attique (région)"><name sortKey="Kastritis, Efstathios" sort="Kastritis, Efstathios" uniqKey="Kastritis E" first="Efstathios" last="Kastritis">Efstathios Kastritis</name>
</region>
<name sortKey="Terpos, Evangelos" sort="Terpos, Evangelos" uniqKey="Terpos E" first="Evangelos" last="Terpos">Evangelos Terpos</name>
</country>
<country name="Suède"><region name="Svealand"><name sortKey="Kimby, Eva" sort="Kimby, Eva" uniqKey="Kimby E" first="Eva" last="Kimby">Eva Kimby</name>
</region>
</country>
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</affiliations>
</record>

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Response assessment in Waldenström macroglobulinaemia: update from the Vlth International Workshop

Response assessment in Waldenström macroglobulinaemia: update from the Vlth International Workshop

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