Drug Delivery: Antibody‐Functionalized Porous Silicon Nanoparticles for Vectorization of Hydrophobic Drugs (Adv. Healthcare Mater. 5/2013)
Identifieur interne : 004A80 ( Main/Exploration ); précédent : 004A79; suivant : 004A81Drug Delivery: Antibody‐Functionalized Porous Silicon Nanoparticles for Vectorization of Hydrophobic Drugs (Adv. Healthcare Mater. 5/2013)
Auteurs : Emilie Secret [France] ; Kevin Smith [Australie] ; Valentina Dubljevic [Australie] ; Eli Moore [Australie] ; Peter Macardle [Australie] ; Bahman Delalat [Australie] ; Mary-Louise Rogers [Australie] ; Terrance G. Johns [Australie] ; Jean-Olivier Durand [France] ; Frédérique Cunin [France, Australie] ; Nicolas H. Voelcker [Australie]Source :
- Advanced Healthcare Materials [ 2192-2640 ] ; 2013-05.
Abstract
Biodegradable porous silicon nanoparticles (pSiNP) functionalized with cancer cell targeting antibodies and loaded with the hydrophobic anti‐cancer drug camptothecin are developed by Nicolas H. Voelcker, Frédérique Cunin, and co‐workers on page 718. High targeting and killing efficiency is demonstrated in vitro on three types of cancer cells: neuroblastoma, glioblastoma and lymphoma cells.
Url:
DOI: 10.1002/adhm.201370025
Affiliations:
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<front><div type="abstract" xml:lang="en">Biodegradable porous silicon nanoparticles (pSiNP) functionalized with cancer cell targeting antibodies and loaded with the hydrophobic anti‐cancer drug camptothecin are developed by Nicolas H. Voelcker, Frédérique Cunin, and co‐workers on page 718. High targeting and killing efficiency is demonstrated in vitro on three types of cancer cells: neuroblastoma, glioblastoma and lymphoma cells.</div>
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