The aging diver: endothelial biochemistry and its potential implications for cardiovascular health.
Identifieur interne : 002743 ( Main/Exploration ); précédent : 002742; suivant : 002744The aging diver: endothelial biochemistry and its potential implications for cardiovascular health.
Auteurs : Simin Berenji Ardestani [Norvège] ; Peter Buzzacott [France] ; Ingrid Eftedal [Norvège]Source :
- Diving and hyperbaric medicine [ 1833-3516 ] ; 2015.
Descripteurs français
- KwdFr :
- Acclimatation, Adulte, Adulte d'âge moyen, Animaux, Athérosclérose (étiologie), Cause de décès, Endothélium vasculaire (physiologie), Facteurs de l'âge, Facteurs sexuels, Humains, Lapins, Mal de décompression (étiologie), Maladies cardiovasculaires (mortalité), Maladies cardiovasculaires (étiologie), Monoxyde d'azote (métabolisme), Plongée (effets indésirables), Plongée (physiologie), Rats, Risque, Sujet âgé, Vieillissement (physiologie).
- MESH :
- effets indésirables : Plongée.
- mortalité : Maladies cardiovasculaires.
- métabolisme : Monoxyde d'azote.
- physiologie : Endothélium vasculaire, Plongée, Vieillissement.
- étiologie : Athérosclérose, Mal de décompression, Maladies cardiovasculaires.
- Acclimatation, Adulte, Adulte d'âge moyen, Animaux, Cause de décès, Facteurs de l'âge, Facteurs sexuels, Humains, Lapins, Rats, Risque, Sujet âgé.
English descriptors
- KwdEn :
- Acclimatization, Adult, Age Factors, Aged, Aging (physiology), Animals, Atherosclerosis (etiology), Cardiovascular Diseases (etiology), Cardiovascular Diseases (mortality), Cause of Death, Decompression Sickness (etiology), Diving (adverse effects), Diving (physiology), Endothelium, Vascular (physiology), Humans, Middle Aged, Nitric Oxide (metabolism), Rabbits, Rats, Risk, Sex Factors.
- MESH :
- chemical , metabolism : Nitric Oxide.
- adverse effects : Diving.
- etiology : Atherosclerosis, Cardiovascular Diseases, Decompression Sickness.
- mortality : Cardiovascular Diseases.
- physiology : Aging, Diving, Endothelium, Vascular.
- Acclimatization, Adult, Age Factors, Aged, Animals, Cause of Death, Humans, Middle Aged, Rabbits, Rats, Risk, Sex Factors.
Abstract
Divers are exposed to circulatory stress that directly affects the endothelial lining of blood vessels, and even asymptomatic dives are associated with inflammatory responses, microparticle release and endothelial dysfunction. As humans age, there is a relative increase in the risk of cardiovascular disease, attributed in part to declining endothelial function. Whether extensive diving in the older diver increases the risk of disease as a result of accumulated circulatory stress or provides protection through processes of acclimatization remains an open question. We provide a brief review of current knowledge about the separate effects of diving and aging on the vascular endothelium in humans and rodents, and discuss the available data on their combined effects. The aim is to elucidate possible outcomes of the interplay between exogenous and endogenous stress factors for endothelial function and to question potential implications for cardiovascular health in the aging diver.
PubMed: 26687310
Affiliations:
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when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acclimatization</term><term>Adult</term><term>Age Factors</term><term>Aged</term><term>Aging (physiology)</term><term>Animals</term><term>Atherosclerosis (etiology)</term><term>Cardiovascular Diseases (etiology)</term><term>Cardiovascular Diseases (mortality)</term><term>Cause of Death</term><term>Decompression Sickness (etiology)</term><term>Diving (adverse effects)</term><term>Diving (physiology)</term><term>Endothelium, Vascular (physiology)</term><term>Humans</term><term>Middle Aged</term><term>Nitric Oxide (metabolism)</term><term>Rabbits</term><term>Rats</term><term>Risk</term><term>Sex Factors</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Acclimatation</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Animaux</term><term>Athérosclérose (étiologie)</term><term>Cause de décès</term><term>Endothélium vasculaire (physiologie)</term><term>Facteurs de l'âge</term><term>Facteurs sexuels</term><term>Humains</term><term>Lapins</term><term>Mal de décompression (étiologie)</term><term>Maladies cardiovasculaires (mortalité)</term><term>Maladies cardiovasculaires (étiologie)</term><term>Monoxyde d'azote (métabolisme)</term><term>Plongée (effets indésirables)</term><term>Plongée (physiologie)</term><term>Rats</term><term>Risque</term><term>Sujet âgé</term><term>Vieillissement (physiologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Nitric Oxide</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Diving</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Plongée</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Atherosclerosis</term><term>Cardiovascular Diseases</term><term>Decompression 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Death</term><term>Humans</term><term>Middle Aged</term><term>Rabbits</term><term>Rats</term><term>Risk</term><term>Sex Factors</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Acclimatation</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Animaux</term><term>Cause de décès</term><term>Facteurs de l'âge</term><term>Facteurs sexuels</term><term>Humains</term><term>Lapins</term><term>Rats</term><term>Risque</term><term>Sujet âgé</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Divers are exposed to circulatory stress that directly affects the endothelial lining of blood vessels, and even asymptomatic dives are associated with inflammatory responses, microparticle release and endothelial dysfunction. As humans age, there is a relative increase in the risk of cardiovascular disease, attributed in part to declining endothelial function. Whether extensive diving in the older diver increases the risk of disease as a result of accumulated circulatory stress or provides protection through processes of acclimatization remains an open question. We provide a brief review of current knowledge about the separate effects of diving and aging on the vascular endothelium in humans and rodents, and discuss the available data on their combined effects. The aim is to elucidate possible outcomes of the interplay between exogenous and endogenous stress factors for endothelial function and to question potential implications for cardiovascular health in the aging diver.</div></front></TEI><affiliations><list><country><li>France</li><li>Norvège</li></country><region><li>Région Bretagne</li><li>Trøndelag</li></region><settlement><li>Brest</li><li>Trondheim</li></settlement></list><tree><country name="Norvège"><region name="Trøndelag"><name sortKey="Berenji Ardestani, Simin" sort="Berenji Ardestani, Simin" uniqKey="Berenji Ardestani S" first="Simin" last="Berenji Ardestani">Simin Berenji Ardestani</name></region><name sortKey="Eftedal, Ingrid" sort="Eftedal, Ingrid" uniqKey="Eftedal I" first="Ingrid" last="Eftedal">Ingrid Eftedal</name></country><country name="France"><region name="Région Bretagne"><name sortKey="Buzzacott, Peter" sort="Buzzacott, Peter" uniqKey="Buzzacott P" first="Peter" last="Buzzacott">Peter Buzzacott</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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