Efficacy and safety of ticagrelor for long-term secondary prevention of atherothrombotic events in relation to renal function: insights from the PEGASUS-TIMI 54 trial.
Identifieur interne : 002011 ( Main/Exploration ); précédent : 002010; suivant : 002012Efficacy and safety of ticagrelor for long-term secondary prevention of atherothrombotic events in relation to renal function: insights from the PEGASUS-TIMI 54 trial.
Auteurs : Giulia Magnani [États-Unis] ; Robert F. Storey [Royaume-Uni] ; Gabriel Steg [France] ; Deepak L. Bhatt [États-Unis] ; Marc Cohen [États-Unis] ; Julia Kuder [États-Unis] ; Kyungah Im [États-Unis] ; Philip Aylward [Australie] ; Diego Ardissino [Italie] ; Daniel Isaza [Colombie] ; Alexander Parkhomenko [Ukraine] ; Assen R. Goudev [Bulgarie] ; Mikael Dellborg [Suède] ; Frederic Kontny [Norvège] ; Ramon Corbalan [Chili] ; Felix Medina [Pérou] ; Eva C. Jensen [Suède] ; Peter Held [Suède] ; Eugene Braunwald [États-Unis] ; Marc S. Sabatine [États-Unis] ; Marc P. Bonaca [Serbie]Source :
- European heart journal [ 1522-9645 ] ; 2016.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Adénosine (administration et posologie), Adénosine (analogues et dérivés), Adénosine (effets indésirables), Antagonistes des récepteurs purinergiques P2Y (administration et posologie), Antagonistes des récepteurs purinergiques P2Y (effets indésirables), Calendrier d'administration des médicaments, Estimation de Kaplan-Meier, Facteurs de risque, Femelle, Humains, Hémorragie (), Infarctus du myocarde (mortalité), Infarctus du myocarde (traitement médicamenteux), Insuffisance rénale chronique (), Insuffisance rénale chronique (mortalité), Maladie des artères coronaires (), Maladie des artères coronaires (mortalité), Mâle, Résultat thérapeutique, Sujet âgé, Thrombose coronarienne (), Thrombose coronarienne (mortalité).
- MESH :
- administration et posologie : Adénosine, Antagonistes des récepteurs purinergiques P2Y.
- analogues et dérivés : Adénosine.
- effets indésirables : Adénosine, Antagonistes des récepteurs purinergiques P2Y.
- mortalité : Infarctus du myocarde, Insuffisance rénale chronique, Maladie des artères coronaires, Thrombose coronarienne.
- traitement médicamenteux : Infarctus du myocarde.
- Adulte d'âge moyen, Calendrier d'administration des médicaments, Estimation de Kaplan-Meier, Facteurs de risque, Femelle, Humains, Hémorragie, Insuffisance rénale chronique, Maladie des artères coronaires, Mâle, Résultat thérapeutique, Sujet âgé, Thrombose coronarienne.
English descriptors
- KwdEn :
- Adenosine (administration & dosage), Adenosine (adverse effects), Adenosine (analogs & derivatives), Aged, Coronary Artery Disease (mortality), Coronary Artery Disease (prevention & control), Coronary Thrombosis (mortality), Coronary Thrombosis (prevention & control), Drug Administration Schedule, Female, Hemorrhage (chemically induced), Humans, Kaplan-Meier Estimate, Male, Middle Aged, Myocardial Infarction (drug therapy), Myocardial Infarction (mortality), Purinergic P2Y Receptor Antagonists (administration & dosage), Purinergic P2Y Receptor Antagonists (adverse effects), Renal Insufficiency, Chronic (complications), Renal Insufficiency, Chronic (mortality), Risk Factors, Treatment Outcome.
- MESH :
- chemical , administration & dosage : Adenosine, Purinergic P2Y Receptor Antagonists.
- chemical , adverse effects : Adenosine, Purinergic P2Y Receptor Antagonists.
- chemical , analogs & derivatives : Adenosine.
- chemically induced : Hemorrhage.
- complications : Renal Insufficiency, Chronic.
- drug therapy : Myocardial Infarction.
- mortality : Coronary Artery Disease, Coronary Thrombosis, Myocardial Infarction, Renal Insufficiency, Chronic.
- prevention & control : Coronary Artery Disease, Coronary Thrombosis.
- Aged, Drug Administration Schedule, Female, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Risk Factors, Treatment Outcome.
Abstract
We evaluated the relationship of renal function and ischaemic and bleeding risk as well as the efficacy and safety of ticagrelor in stable patients with prior myocardial infarction (MI).
DOI: 10.1093/eurheartj/ehv482
PubMed: 26443023
Affiliations:
- Australie, Bulgarie, Chili, Colombie, France, Italie, Norvège, Pérou, Royaume-Uni, Serbie, Suède, Ukraine, États-Unis
- Massachusetts, Sofia-ville (oblast), État de New York, Île-de-France
- Paris, Sofia
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 002546
- to stream PubMed, to step Curation: 002478
- to stream PubMed, to step Checkpoint: 002478
- to stream Ncbi, to step Merge: 002B86
- to stream Ncbi, to step Curation: 002B86
- to stream Ncbi, to step Checkpoint: 002B86
- to stream Main, to step Merge: 002010
- to stream Main, to step Curation: 002011
Le document en format XML
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<author><name sortKey="Sabatine, Marc S" sort="Sabatine, Marc S" uniqKey="Sabatine M" first="Marc S" last="Sabatine">Marc S. Sabatine</name>
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<author><name sortKey="Bonaca, Marc P" sort="Bonaca, Marc P" uniqKey="Bonaca M" first="Marc P" last="Bonaca">Marc P. Bonaca</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Efficacy and safety of ticagrelor for long-term secondary prevention of atherothrombotic events in relation to renal function: insights from the PEGASUS-TIMI 54 trial.</title>
<author><name sortKey="Magnani, Giulia" sort="Magnani, Giulia" uniqKey="Magnani G" first="Giulia" last="Magnani">Giulia Magnani</name>
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<country xml:lang="fr">France</country>
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<author><name sortKey="Im, Kyungah" sort="Im, Kyungah" uniqKey="Im K" first="Kyungah" last="Im">Kyungah Im</name>
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<author><name sortKey="Aylward, Philip" sort="Aylward, Philip" uniqKey="Aylward P" first="Philip" last="Aylward">Philip Aylward</name>
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<author><name sortKey="Ardissino, Diego" sort="Ardissino, Diego" uniqKey="Ardissino D" first="Diego" last="Ardissino">Diego Ardissino</name>
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<country xml:lang="fr">Italie</country>
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<author><name sortKey="Isaza, Daniel" sort="Isaza, Daniel" uniqKey="Isaza D" first="Daniel" last="Isaza">Daniel Isaza</name>
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<country xml:lang="fr">Colombie</country>
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<author><name sortKey="Parkhomenko, Alexander" sort="Parkhomenko, Alexander" uniqKey="Parkhomenko A" first="Alexander" last="Parkhomenko">Alexander Parkhomenko</name>
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<country xml:lang="fr">Ukraine</country>
<wicri:regionArea>Ukranian Strazhesko Institute of Cardiology, Kiev</wicri:regionArea>
<wicri:noRegion>Kiev</wicri:noRegion>
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<author><name sortKey="Goudev, Assen R" sort="Goudev, Assen R" uniqKey="Goudev A" first="Assen R" last="Goudev">Assen R. Goudev</name>
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<author><name sortKey="Medina, Felix" sort="Medina, Felix" uniqKey="Medina F" first="Felix" last="Medina">Felix Medina</name>
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<author><name sortKey="Jensen, Eva C" sort="Jensen, Eva C" uniqKey="Jensen E" first="Eva C" last="Jensen">Eva C. Jensen</name>
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<author><name sortKey="Held, Peter" sort="Held, Peter" uniqKey="Held P" first="Peter" last="Held">Peter Held</name>
<affiliation wicri:level="1"><nlm:affiliation>AstraZenecaAZ R&D, Molndal, Sweden.</nlm:affiliation>
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<author><name sortKey="Braunwald, Eugene" sort="Braunwald, Eugene" uniqKey="Braunwald E" first="Eugene" last="Braunwald">Eugene Braunwald</name>
<affiliation wicri:level="2"><nlm:affiliation>TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
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<author><name sortKey="Sabatine, Marc S" sort="Sabatine, Marc S" uniqKey="Sabatine M" first="Marc S" last="Sabatine">Marc S. Sabatine</name>
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</author>
<author><name sortKey="Bonaca, Marc P" sort="Bonaca, Marc P" uniqKey="Bonaca M" first="Marc P" last="Bonaca">Marc P. Bonaca</name>
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<country wicri:rule="url">Serbie</country>
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</analytic>
<series><title level="j">European heart journal</title>
<idno type="eISSN">1522-9645</idno>
<imprint><date when="2016" type="published">2016</date>
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<front><div type="abstract" xml:lang="en">We evaluated the relationship of renal function and ischaemic and bleeding risk as well as the efficacy and safety of ticagrelor in stable patients with prior myocardial infarction (MI).</div>
</front>
</TEI>
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