Predictive factors for successful renal denervation: should we use them in clinical trials?
Identifieur interne : 000573 ( Main/Exploration ); précédent : 000572; suivant : 000574Predictive factors for successful renal denervation: should we use them in clinical trials?
Auteurs : Nicolas Barber-Chamoux [France] ; Murray D. Esler [Australie]Source :
- European journal of clinical investigation [ 1365-2362 ] ; 2017.
Abstract
Renal denervation (RDN) is facing various challenges to its initial claimed value in hypertension treatment. Major concerns are the choice of the patients and the technical efficacy of the RDN. Different factors have been described as predicting the capacity of RDN to decrease blood pressure. These factors are related to the patients, the procedure and the tools to confirm successful neural ablation. Their use in future trials should help to improve RDN trials understanding and outcomes. This review summarizes the different predictive factors available and their potential benefits in patient selection and in procedure guidance.
DOI: 10.1111/eci.12792
PubMed: 28771706
Affiliations:
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<front><div type="abstract" xml:lang="en">Renal denervation (RDN) is facing various challenges to its initial claimed value in hypertension treatment. Major concerns are the choice of the patients and the technical efficacy of the RDN. Different factors have been described as predicting the capacity of RDN to decrease blood pressure. These factors are related to the patients, the procedure and the tools to confirm successful neural ablation. Their use in future trials should help to improve RDN trials understanding and outcomes. This review summarizes the different predictive factors available and their potential benefits in patient selection and in procedure guidance.</div>
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