AustralieFrV1, Main, Curation, bibRecord, 008891

Age patterns in the prevalence of DSM-IV depressive/anxiety disorders with and without physical co-morbidity

Identifieur interne : 008891 ( Main/Curation ); précédent : 008890; suivant : 008892

Age patterns in the prevalence of DSM-IV depressive/anxiety disorders with and without physical co-morbidity

Auteurs : K. M. Scott [Nouvelle-Zélande] ; M. Von Korff [États-Unis] ; J. Alonso [Espagne] ; M. Angermeyer [Autriche] ; E. J. Bromet [États-Unis] ; R. Bruffaerts [Belgique] ; G. De Girolamo [Italie] ; R. De Graaf [Pays-Bas] ; A. Fernandez [Espagne] ; O. Gureje [Nigeria] ; Y. He [République populaire de Chine] ; R. C. Kessler [États-Unis] ; V. Kovess [France] ; D. Levinson [Israël] ; M. E. Medina-Mora [Mexique] ; Z. Mneimneh [Liban] ; M. A. Oakley Browne [Australie] ; J. Posada-Villa [Colombie] ; H. Tachimori [Japon] ; D. Williams [États-Unis]

Source :

Psychological Medicine [ 0033-2917 ] ; 2008.

RBID : ISTEX:921FBF9B3BFC313E02080622B9E473D4B0E5E969

Descripteurs français

Pascal (Inist)
- Age, Association morbide, Diagnostic and Statistical Manual IV, Environnement social, Etat dépressif, Etude comparative, Etude en population générale, Homme, International, Maladie somatique, Prévalence, Santé mentale, Santé publique, Sénescence, Trouble anxieux.
Wicri :
- topic : Homme, Santé mentale, Santé publique.

English descriptors

KwdEn :
- Age, Anxiety disorder, Comparative study, Concomitant disease, Depression, Diagnostic and Statistical Manual IV, Human, International, Mental health, Population-based survey, Prevalence, Public health, Senescence, Social environment, Somatic disease.

Abstract

Background Physical morbidity is a potent risk factor for depression onset and clearly increases with age, yet prior research has often found depressive disorders to decrease with age. This study tests the possibility that the relationship between age and mental disorders differs as a function of physical co-morbidity. Method Eighteen general population surveys were carried out among household-residing adults as part of the World Mental Health (WMH) surveys initiative (n=42 697). DSM-IV disorders were assessed using face-to-face interviews with the Composite International Diagnostic Interview (CIDI 3.0). The effect of age was estimated for 12-month depressive and/or anxiety disorders with and without physical or pain co-morbidity, and for physical and/or pain conditions without mental co-morbidity. Results Depressive and anxiety disorders decreased with age, a result that cannot be explained by organic exclusion criteria. No significant difference was found in the relationship between mental disorders and age as a function of physical/pain co-morbidity. The majority of older persons have chronic physical or pain conditions without co-morbid mental disorders; by contrast, the majority of those with mental disorders have physical/pain co-morbidity, particularly among the older age groups. Conclusions CIDI-diagnosed depressive and anxiety disorders in the general population decrease with age, despite greatly increasing physical morbidity with age. Physical morbidity among persons with mental disorder is the norm, particularly in older populations. Health professionals, including mental health professionals, need to address barriers to the management of physical co-morbidity among those with mental disorders.

Url:

DOI: 10.1017/S0033291708003413

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<wicri:regionArea>Department of Society, Human Development and Health, Harvard School of Public Health, Harvard University, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
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<series><title level="j">Psychological Medicine</title>
<title level="j" type="abbrev">Psychol. Med.</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age</term>
<term>Anxiety disorder</term>
<term>Comparative study</term>
<term>Concomitant disease</term>
<term>Depression</term>
<term>Diagnostic and Statistical Manual IV</term>
<term>Human</term>
<term>International</term>
<term>Mental health</term>
<term>Population-based survey</term>
<term>Prevalence</term>
<term>Public health</term>
<term>Senescence</term>
<term>Social environment</term>
<term>Somatic disease</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Age</term>
<term>Association morbide</term>
<term>Diagnostic and Statistical Manual IV</term>
<term>Environnement social</term>
<term>Etat dépressif</term>
<term>Etude comparative</term>
<term>Etude en population générale</term>
<term>Homme</term>
<term>International</term>
<term>Maladie somatique</term>
<term>Prévalence</term>
<term>Santé mentale</term>
<term>Santé publique</term>
<term>Sénescence</term>
<term>Trouble anxieux</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
<term>Santé mentale</term>
<term>Santé publique</term>
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<front><div type="abstract">Background Physical morbidity is a potent risk factor for depression onset and clearly increases with age, yet prior research has often found depressive disorders to decrease with age. This study tests the possibility that the relationship between age and mental disorders differs as a function of physical co-morbidity. Method Eighteen general population surveys were carried out among household-residing adults as part of the World Mental Health (WMH) surveys initiative (n=42 697). DSM-IV disorders were assessed using face-to-face interviews with the Composite International Diagnostic Interview (CIDI 3.0). The effect of age was estimated for 12-month depressive and/or anxiety disorders with and without physical or pain co-morbidity, and for physical and/or pain conditions without mental co-morbidity. Results Depressive and anxiety disorders decreased with age, a result that cannot be explained by organic exclusion criteria. No significant difference was found in the relationship between mental disorders and age as a function of physical/pain co-morbidity. The majority of older persons have chronic physical or pain conditions without co-morbid mental disorders; by contrast, the majority of those with mental disorders have physical/pain co-morbidity, particularly among the older age groups. Conclusions CIDI-diagnosed depressive and anxiety disorders in the general population decrease with age, despite greatly increasing physical morbidity with age. Physical morbidity among persons with mental disorder is the norm, particularly in older populations. Health professionals, including mental health professionals, need to address barriers to the management of physical co-morbidity among those with mental disorders.</div>
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<sZ>6 aut.</sZ>
</inist:fA14>
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<sZ>7 aut.</sZ>
</inist:fA14>
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</affiliation>
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<sZ>8 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
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<sZ>10 aut.</sZ>
</inist:fA14>
<country>Nigeria</country>
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</affiliation>
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<author><name sortKey="He, Y" sort="He, Y" uniqKey="He Y" first="Y." last="He">Y. He</name>
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<sZ>11 aut.</sZ>
</inist:fA14>
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</author>
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<sZ>12 aut.</sZ>
</inist:fA14>
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<sZ>13 aut.</sZ>
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</affiliation>
</author>
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<sZ>14 aut.</sZ>
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</author>
<author><name sortKey="Medina Mora, M E" sort="Medina Mora, M E" uniqKey="Medina Mora M" first="M. E." last="Medina-Mora">M. E. Medina-Mora</name>
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<s2>Mexico City</s2>
<s3>MEX</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>Mexique</country>
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</affiliation>
</author>
<author><name sortKey="Mneimneh, Z" sort="Mneimneh, Z" uniqKey="Mneimneh Z" first="Z." last="Mneimneh">Z. Mneimneh</name>
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<s3>LBN</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Liban</country>
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</affiliation>
</author>
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<sZ>17 aut.</sZ>
</inist:fA14>
<country>Australie</country>
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</author>
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<s3>COL</s3>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>Colombie</country>
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</author>
<author><name sortKey="Tachimori, H" sort="Tachimori, H" uniqKey="Tachimori H" first="H." last="Tachimori">H. Tachimori</name>
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<s3>JPN</s3>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<placeName><settlement type="city">Tokyo</settlement>
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<s3>USA</s3>
<sZ>20 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Age patterns in the prevalence of DSM-IV depressive/anxiety disorders with and without physical co-morbidity</title>
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<s2>Wellington</s2>
<s3>NZL</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>Nouvelle-Zélande</country>
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</affiliation>
</author>
<author><name sortKey="Von Korff, M" sort="Von Korff, M" uniqKey="Von Korff M" first="M." last="Von Korff">M. Von Korff</name>
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</inist:fA14>
<country>États-Unis</country>
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</affiliation>
</author>
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</author>
<author><name sortKey="De Girolamo, G" sort="De Girolamo, G" uniqKey="De Girolamo G" first="G." last="De Girolamo">G. De Girolamo</name>
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<placeName><settlement type="city">Barcelone</settlement>
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<s2>Ibadan</s2>
<s3>NGA</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Nigeria</country>
<wicri:noRegion>Ibadan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="He, Y" sort="He, Y" uniqKey="He Y" first="Y." last="He">Y. He</name>
<affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Shanghai Mental Health Center</s1>
<s2>Shanghai</s2>
<s3>CHN</s3>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
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</affiliation>
</author>
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<s2>Boston, MA</s2>
<s3>USA</s3>
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</inist:fA14>
<country>États-Unis</country>
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<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
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<region type="old region">Île-de-France</region>
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</placeName>
</affiliation>
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<author><name sortKey="Levinson, D" sort="Levinson, D" uniqKey="Levinson D" first="D." last="Levinson">D. Levinson</name>
<affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Mental Health Services, Ministry of Health</s1>
<s2>Jerusalem</s2>
<s3>ISR</s3>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Israël</country>
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</author>
<author><name sortKey="Medina Mora, M E" sort="Medina Mora, M E" uniqKey="Medina Mora M" first="M. E." last="Medina-Mora">M. E. Medina-Mora</name>
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<s3>MEX</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>Mexique</country>
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</affiliation>
</author>
<author><name sortKey="Mneimneh, Z" sort="Mneimneh, Z" uniqKey="Mneimneh Z" first="Z." last="Mneimneh">Z. Mneimneh</name>
<affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Institute for Development Research Advocacy and Applied Care (IDRAAC)</s1>
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<s3>LBN</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Liban</country>
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</affiliation>
</author>
<author><name sortKey="Oakley Browne, M A" sort="Oakley Browne, M A" uniqKey="Oakley Browne M" first="M. A." last="Oakley Browne">M. A. Oakley Browne</name>
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<s3>AUS</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>Australie</country>
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</affiliation>
</author>
<author><name sortKey="Posada Villa, J" sort="Posada Villa, J" uniqKey="Posada Villa J" first="J." last="Posada-Villa">J. Posada-Villa</name>
<affiliation wicri:level="1"><inist:fA14 i1="18"><s1>Colegio Mayor de Cundinamarca University</s1>
<s2>Bogota</s2>
<s3>COL</s3>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>Colombie</country>
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</affiliation>
</author>
<author><name sortKey="Tachimori, H" sort="Tachimori, H" uniqKey="Tachimori H" first="H." last="Tachimori">H. Tachimori</name>
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<s3>JPN</s3>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<placeName><settlement type="city">Tokyo</settlement>
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</placeName>
</affiliation>
</author>
<author><name sortKey="Williams, D" sort="Williams, D" uniqKey="Williams D" first="D." last="Williams">D. Williams</name>
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<sZ>20 aut.</sZ>
</inist:fA14>
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<series><title level="j" type="main">Psychological medicine : (Print)</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age</term>
<term>Anxiety disorder</term>
<term>Comparative study</term>
<term>Concomitant disease</term>
<term>Depression</term>
<term>Diagnostic and Statistical Manual IV</term>
<term>Human</term>
<term>International</term>
<term>Mental health</term>
<term>Population-based survey</term>
<term>Prevalence</term>
<term>Public health</term>
<term>Senescence</term>
<term>Social environment</term>
<term>Somatic disease</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Age</term>
<term>Prévalence</term>
<term>Santé publique</term>
<term>Diagnostic and Statistical Manual IV</term>
<term>Etat dépressif</term>
<term>Trouble anxieux</term>
<term>Etude comparative</term>
<term>Association morbide</term>
<term>Sénescence</term>
<term>Santé mentale</term>
<term>Environnement social</term>
<term>International</term>
<term>Homme</term>
<term>Maladie somatique</term>
<term>Etude en population générale</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Santé publique</term>
<term>Santé mentale</term>
<term>Homme</term>
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<front><div type="abstract" xml:lang="en">Background. Physical morbidity is a potent risk factor for depression onset and clearly increases with age, yet prior research has often found depressive disorders to decrease with age. This study tests the possibility that the relationship between age and mental disorders differs as a function of physical co-morbidity. Method. Eighteen general population surveys were carried out among household-residing adults as part of the World Mental Health (WMH) surveys initiative (n=42697). DSM-IV disorders were assessed using face-to-face interviews with the Composite International Diagnostic Interview (CIDI 3.0). The effect of age was estimated for 12-month depressive and/or anxiety disorders with and without physical or pain co-morbidity, and for physical and/or pain conditions without mental co-morbidity. Results. Depressive and anxiety disorders decreased with age, a result that cannot be explained by organic exclusion criteria. No significant difference was found in the relationship between mental disorders and age as a function of physical/pain co-morbidity. The majority of older persons have chronic physical or pain conditions without co-morbid mental disorders; by contrast, the majority of those with mental disorders have physical/pain co-morbidity, particularly among the older age groups. Conclusions. CIDI-diagnosed depressive and anxiety disorders in the general population decrease with age, despite greatly increasing physical morbidity with age. Physical morbidity among persons with mental disorder is the norm, particularly in older populations. Health professionals, including mental health professionals, need to address barriers to the management of physical co-morbidity among those with mental disorders.</div>
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<author><name sortKey="Scott, K M" sort="Scott, K M" uniqKey="Scott K" first="K. M." last="Scott">K. M. Scott</name>
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<author><name sortKey="Von Korff, M" sort="Von Korff, M" uniqKey="Von Korff M" first="M." last="Von Korff">M. Von Korff</name>
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<author><name sortKey="Alonso, J" sort="Alonso, J" uniqKey="Alonso J" first="J." last="Alonso">J. Alonso</name>
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<author><name sortKey="Bromet, E J" sort="Bromet, E J" uniqKey="Bromet E" first="E. J." last="Bromet">E. J. Bromet</name>
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<author><name sortKey="De Girolamo, G" sort="De Girolamo, G" uniqKey="De Girolamo G" first="G." last="De Girolamo">G. De Girolamo</name>
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<author><name sortKey="Oakley Browne, M A" sort="Oakley Browne, M A" uniqKey="Oakley Browne M" first="M. A." last="Oakley Browne">M. A. Oakley Browne</name>
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<author><name sortKey="Scott, K M" sort="Scott, K M" uniqKey="Scott K" first="K. M." last="Scott">K. M. Scott</name>
<affiliation wicri:level="1"><country xml:lang="fr">Nouvelle-Zélande</country>
<wicri:regionArea>Department of Psychological Medicine, Otago University, Wellington</wicri:regionArea>
<wicri:noRegion>Wellington</wicri:noRegion>
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<affiliation wicri:level="1"><country wicri:rule="url">Nouvelle-Zélande</country>
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<author><name sortKey="Von Korff, M" sort="Von Korff, M" uniqKey="Von Korff M" first="M." last="Von Korff">M. Von Korff</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, WA</wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Alonso, J" sort="Alonso, J" uniqKey="Alonso J" first="J." last="Alonso">J. Alonso</name>
<affiliation wicri:level="3"><country xml:lang="fr">Espagne</country>
<wicri:regionArea>Health Services Research Unit, Institute Municipal d'Investigacio Medica (IMIM), and CIBER en Epidemiologia y Salud Publica (CIBERESP), Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Angermeyer, M" sort="Angermeyer, M" uniqKey="Angermeyer M" first="M." last="Angermeyer">M. Angermeyer</name>
<affiliation wicri:level="1"><country xml:lang="fr">Autriche</country>
<wicri:regionArea>Center for Public Mental Health</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Bromet, E J" sort="Bromet, E J" uniqKey="Bromet E" first="E. J." last="Bromet">E. J. Bromet</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>SUNY Stony Brook, Stony Brook, New York</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
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<author><name sortKey="Bruffaerts, R" sort="Bruffaerts, R" uniqKey="Bruffaerts R" first="R." last="Bruffaerts">R. Bruffaerts</name>
<affiliation wicri:level="1"><country xml:lang="fr">Belgique</country>
<wicri:regionArea>Department of Neurosciences and Psychiatry, University Hospital, Gasthuisberg, Leuven</wicri:regionArea>
<wicri:noRegion>Leuven</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="De Girolamo, G" sort="De Girolamo, G" uniqKey="De Girolamo G" first="G." last="De Girolamo">G. De Girolamo</name>
<affiliation wicri:level="1"><country xml:lang="fr">Italie</country>
<wicri:regionArea>Regional Health Care Agency, Emilia-Romagna Region, Bologna</wicri:regionArea>
<wicri:noRegion>Bologna</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="De Graaf, R" sort="De Graaf, R" uniqKey="De Graaf R" first="R." last="De Graaf">R. De Graaf</name>
<affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Netherlands Institute of Mental Health and Addiction, Utrecht</wicri:regionArea>
<placeName><settlement type="city">Utrecht</settlement>
<region nuts="2" type="province">Utrecht (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fernandez, A" sort="Fernandez, A" uniqKey="Fernandez A" first="A." last="Fernandez">A. Fernandez</name>
<affiliation wicri:level="3"><country xml:lang="fr">Espagne</country>
<wicri:regionArea>Fundació Sant Joan de Déu Research and Development Unit, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gureje, O" sort="Gureje, O" uniqKey="Gureje O" first="O." last="Gureje">O. Gureje</name>
<affiliation wicri:level="1"><country xml:lang="fr">Nigeria</country>
<wicri:regionArea>Department of Psychiatry, University College Hospital, Ibadan</wicri:regionArea>
<wicri:noRegion>Ibadan</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="He, Y" sort="He, Y" uniqKey="He Y" first="Y." last="He">Y. He</name>
<affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Shanghai Mental Health Center, Shanghai</wicri:regionArea>
<wicri:noRegion>Shanghai</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kessler, R C" sort="Kessler, R C" uniqKey="Kessler R" first="R. C." last="Kessler">R. C. Kessler</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Health Care Policy, Harvard Medical School, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kovess, V" sort="Kovess, V" uniqKey="Kovess V" first="V." last="Kovess">V. Kovess</name>
<affiliation wicri:level="3"><country xml:lang="fr">France</country>
<wicri:regionArea>Fondation MGEN Pour La Santé Publique, Université Paris 5, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Levinson, D" sort="Levinson, D" uniqKey="Levinson D" first="D." last="Levinson">D. Levinson</name>
<affiliation wicri:level="1"><country xml:lang="fr">Israël</country>
<wicri:regionArea>Mental Health Services, Ministry of Health, Jerusalem</wicri:regionArea>
<wicri:noRegion>Jerusalem</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Medina Mora, M E" sort="Medina Mora, M E" uniqKey="Medina Mora M" first="M. E." last="Medina-Mora">M. E. Medina-Mora</name>
<affiliation wicri:level="1"><country xml:lang="fr">Mexique</country>
<wicri:regionArea>Department of Epidemiology, National Institute of Psychiatry, Mexico City</wicri:regionArea>
<wicri:noRegion>Mexico City</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mneimneh, Z" sort="Mneimneh, Z" uniqKey="Mneimneh Z" first="Z." last="Mneimneh">Z. Mneimneh</name>
<affiliation wicri:level="1"><country xml:lang="fr">Liban</country>
<wicri:regionArea>Institute for Development Research Advocacy and Applied Care (IDRAAC), Beirut</wicri:regionArea>
<wicri:noRegion>Beirut</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Oakley Browne, M A" sort="Oakley Browne, M A" uniqKey="Oakley Browne M" first="M. A." last="Oakley Browne">M. A. Oakley Browne</name>
<affiliation wicri:level="1"><country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Rural and Indigenous Health, School of Rural Health, Monash University, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Posada Villa, J" sort="Posada Villa, J" uniqKey="Posada Villa J" first="J." last="Posada-Villa">J. Posada-Villa</name>
<affiliation wicri:level="1"><country xml:lang="fr">Colombie</country>
<wicri:regionArea>Colegio Mayor de Cundinamarca University, Bogota</wicri:regionArea>
<wicri:noRegion>Bogota</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tachimori, H" sort="Tachimori, H" uniqKey="Tachimori H" first="H." last="Tachimori">H. Tachimori</name>
<affiliation wicri:level="3"><country xml:lang="fr">Japon</country>
<wicri:regionArea>National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Tokyo</wicri:regionArea>
<placeName><settlement type="city">Tokyo</settlement>
<region type="région">Région de Kantō</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Williams, D" sort="Williams, D" uniqKey="Williams D" first="D." last="Williams">D. Williams</name>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Society, Human Development and Health, Harvard School of Public Health, Harvard University, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
<settlement type="city">Cambridge (Massachusetts)</settlement>
</placeName>
<orgName type="university">Université Harvard</orgName>
</affiliation>
</author>
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<monogr></monogr>
<series><title level="j">Psychological Medicine</title>
<title level="j" type="abbrev">Psychol. Med.</title>
<idno type="ISSN">0033-2917</idno>
<idno type="eISSN">1469-8978</idno>
<imprint><publisher>Cambridge University Press</publisher>
<pubPlace>Cambridge, UK</pubPlace>
<date type="published" when="2008">2008</date>
<biblScope unit="volume">38</biblScope>
<biblScope unit="issue">11</biblScope>
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<front><div type="abstract">Background Physical morbidity is a potent risk factor for depression onset and clearly increases with age, yet prior research has often found depressive disorders to decrease with age. This study tests the possibility that the relationship between age and mental disorders differs as a function of physical co-morbidity. Method Eighteen general population surveys were carried out among household-residing adults as part of the World Mental Health (WMH) surveys initiative (n=42 697). DSM-IV disorders were assessed using face-to-face interviews with the Composite International Diagnostic Interview (CIDI 3.0). The effect of age was estimated for 12-month depressive and/or anxiety disorders with and without physical or pain co-morbidity, and for physical and/or pain conditions without mental co-morbidity. Results Depressive and anxiety disorders decreased with age, a result that cannot be explained by organic exclusion criteria. No significant difference was found in the relationship between mental disorders and age as a function of physical/pain co-morbidity. The majority of older persons have chronic physical or pain conditions without co-morbid mental disorders; by contrast, the majority of those with mental disorders have physical/pain co-morbidity, particularly among the older age groups. Conclusions CIDI-diagnosed depressive and anxiety disorders in the general population decrease with age, despite greatly increasing physical morbidity with age. Physical morbidity among persons with mental disorder is the norm, particularly in older populations. Health professionals, including mental health professionals, need to address barriers to the management of physical co-morbidity among those with mental disorders.</div>
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Age patterns in the prevalence of DSM-IV depressive/anxiety disorders with and without physical co-morbidity

Age patterns in the prevalence of DSM-IV depressive/anxiety disorders with and without physical co-morbidity

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