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A metabolic model for members of the genus Tetrasphaera involved in enhanced biological phosphorus removal

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A metabolic model for members of the genus Tetrasphaera involved in enhanced biological phosphorus removal

Auteurs : Rikke Kristiansen [Danemark] ; Hien Thi Thu Nguyen [Danemark] ; Aaron Marc Saunders [Danemark] ; Jeppe Lund Nielsen [Danemark] ; Reinhard Wimmer [Danemark] ; Vang Quy Le [Danemark] ; Simon Jon Mcilroy [Danemark, Australie] ; Steve Petrovski [Australie] ; Robert J. Seviour [Australie] ; Alexandra Calteau [France] ; K Re Lehmann Nielsen [Danemark] ; Per Halkj R Nielsen [Danemark]

Source :

The ISME Journal [ 1751-7362 ] ; 2012.

RBID : PMC:3578573

Abstract

Members of the genus Tetrasphaera are considered to be putative polyphosphate accumulating organisms (PAOs) in enhanced biological phosphorus removal (EBPR) from wastewater. Although abundant in Danish full-scale wastewater EBPR plants, how similar their ecophysiology is to ‘Candidatus Accumulibacter phosphatis' is unclear, although they may occupy different ecological niches in EBPR communities. The genomes of four Tetrasphaera isolates (T. australiensis, T. japonica, T. elongata and T. jenkinsii) were sequenced and annotated, and the data used to construct metabolic models. These models incorporate central aspects of carbon and phosphorus metabolism critical to understanding their behavior under the alternating anaerobic/aerobic conditions encountered in EBPR systems. Key features of these metabolic pathways were investigated in pure cultures, although poor growth limited their analyses to T. japonica and T. elongata. Based on the models, we propose that under anaerobic conditions the Tetrasphaera-related PAOs take up glucose and ferment this to succinate and other components. They also synthesize glycogen as a storage polymer, using energy generated from the degradation of stored polyphosphate and substrate fermentation. During the aerobic phase, the stored glycogen is catabolized to provide energy for growth and to replenish the intracellular polyphosphate reserves needed for subsequent anaerobic metabolism. They are also able to denitrify. This physiology is markedly different to that displayed by ‘Candidatus Accumulibacter phosphatis', and reveals Tetrasphaera populations to be unusual and physiologically versatile PAOs carrying out denitrification, fermentation and polyphosphate accumulation.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578573

DOI: 10.1038/ismej.2012.136
PubMed: 23178666
PubMed Central: 3578573

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PMC:3578573

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<front><div type="abstract" xml:lang="en"><p>Members of the genus <italic>Tetrasphaera</italic>
 are considered to be putative polyphosphate accumulating organisms (PAOs) in enhanced biological phosphorus removal (EBPR) from wastewater. Although abundant in Danish full-scale wastewater EBPR plants, how similar their ecophysiology is to ‘<italic>Candidatus</italic>
 Accumulibacter phosphatis' is unclear, although they may occupy different ecological niches in EBPR communities. The genomes of four <italic>Tetrasphaera</italic>
 isolates (<italic>T. australiensis</italic>
, <italic>T. japonica</italic>
, <italic>T. elongata</italic>
 and <italic>T. jenkinsii</italic>
) were sequenced and annotated, and the data used to construct metabolic models. These models incorporate central aspects of carbon and phosphorus metabolism critical to understanding their behavior under the alternating anaerobic/aerobic conditions encountered in EBPR systems. Key features of these metabolic pathways were investigated in pure cultures, although poor growth limited their analyses to <italic>T. japonica</italic>
 and <italic>T. elongata</italic>
. Based on the models, we propose that under anaerobic conditions the <italic>Tetrasphaera</italic>
-related PAOs take up glucose and ferment this to succinate and other components. They also synthesize glycogen as a storage polymer, using energy generated from the degradation of stored polyphosphate and substrate fermentation. During the aerobic phase, the stored glycogen is catabolized to provide energy for growth and to replenish the intracellular polyphosphate reserves needed for subsequent anaerobic metabolism. They are also able to denitrify. This physiology is markedly different to that displayed by ‘<italic>Candidatus</italic>
 Accumulibacter phosphatis', and reveals <italic>Tetrasphaera</italic>
 populations to be unusual and physiologically versatile PAOs carrying out denitrification, fermentation and polyphosphate accumulation.</p>
</div>
</front>
</TEI>
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A metabolic model for members of the genus Tetrasphaera involved in enhanced biological phosphorus removal

A metabolic model for members of the genus Tetrasphaera involved in enhanced biological phosphorus removal

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Abstract

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