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25-Azacycloartanol, a potent inhibitor of S-adenosyl-L-methionine-sterol-C-24 and C-28 methyltransferases in higher plant cells

Identifieur interne : 002762 ( Istex/Curation ); précédent : 002761; suivant : 002763

25-Azacycloartanol, a potent inhibitor of S-adenosyl-L-methionine-sterol-C-24 and C-28 methyltransferases in higher plant cells

Auteurs : A. Rahier [France] ; A. S. Narula [Australie] ; P. Benveniste [France] ; P. Schmitt [France]

Source :

RBID : ISTEX:D4144E960D17C235DFDB0E6D55635125D5EBC9AE

Descripteurs français

English descriptors

Abstract

Abstract: 25-azacycloartanol (1) is a potent inhibitor of S-adenosyl-L-methionine-cycloartenol-C-24-methyltransferase and of S-adenosyl-L-methionine-24-methylene lophenol-C-28-methyltransferase, two microsomal enzymes of maize (Zea mays) embryos. Addition of 1 to a suspension of bramble (Rubus fruticosus) cells grown in vitro resulted in a strong decrease of the 24-ethylsterol content and in a dramatic increase of sterols lacking an alkyl group at C-24.

Url:
DOI: 10.1016/0006-291X(80)91513-2

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ISTEX:D4144E960D17C235DFDB0E6D55635125D5EBC9AE

Le document en format XML

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<term>Embryo</term>
<term>I50</term>
<term>Isofucosterol</term>
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<term>Potent inhibitor</term>
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<term>cycloartenol</term>
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<div type="abstract" xml:lang="en">Abstract: 25-azacycloartanol (1) is a potent inhibitor of S-adenosyl-L-methionine-cycloartenol-C-24-methyltransferase and of S-adenosyl-L-methionine-24-methylene lophenol-C-28-methyltransferase, two microsomal enzymes of maize (Zea mays) embryos. Addition of 1 to a suspension of bramble (Rubus fruticosus) cells grown in vitro resulted in a strong decrease of the 24-ethylsterol content and in a dramatic increase of sterols lacking an alkyl group at C-24.</div>
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