Working Party proposal for a revised classification system of renal dysfunction in patients with cirrhosis
Identifieur interne : 002263 ( Istex/Curation ); précédent : 002262; suivant : 002264Working Party proposal for a revised classification system of renal dysfunction in patients with cirrhosis
Auteurs : Florence Wong [Canada] ; Mitra K. Nadim [États-Unis] ; John A. Kellum [États-Unis] ; Francesco Salerno [Italie] ; Rinaldo Bellomo [Australie] ; Alexander Gerbes [Allemagne] ; Paolo Angeli [Italie] ; Richard Moreau [France] ; Andrew Davenport [Royaume-Uni] ; Rajiv Jalan [Royaume-Uni] ; Claudio Ronco [Italie] ; Yuri Genyk [États-Unis] ; Vicente Arroyo [Espagne]Source :
- Gut [ 0017-5749 ] ; 2011-05.
Descripteurs français
- Wicri :
- topic : Maladie rénale.
English descriptors
- KwdEn :
- Acute deterioration, Acute dialysis quality initiative, Acute kidney injury, Acute kidney injury network, Adqi, Ascites, Baseline, Cardiac, Cardiac output, Chronic kidney disease, Cirrhosis, Cirrhotic, Cirrhotic patients, Creatinine, Creatinine clearance, Decompensated cirrhosis, Diagnostic criteria, Dysfunction, Glomerular, Hepatology, Hepatorenal, Hepatorenal syndrome, Hyperdynamic circulation, Hypertension, Intensive care, International ascites club, Kidney, Kidney damage, Kidney disease, Kidney function, Liver cirrhosis, Liver disease, Ltration, Ltration rate, Mdrd6, Mdrd6 formula, Natural history, Nephropathy, Other forms, Pathophysiology, Portal hypertension, Refractory ascites, Renal, Renal blood, Renal disease, Renal dysfunction, Renal failure, Renal function, Renal impairment, Renal vasoconstriction, Rifle criteria, Serum creatinine, Southern california, Splanchnic, Summary statements, Syndrome, Systemic circulation, University college london, Urine, Wong.
- Teeft :
- Acute deterioration, Acute dialysis quality initiative, Acute kidney injury, Acute kidney injury network, Adqi, Ascites, Baseline, Cardiac, Cardiac output, Chronic kidney disease, Cirrhosis, Cirrhotic, Cirrhotic patients, Creatinine, Creatinine clearance, Decompensated cirrhosis, Diagnostic criteria, Dysfunction, Glomerular, Hepatology, Hepatorenal, Hepatorenal syndrome, Hyperdynamic circulation, Hypertension, Intensive care, International ascites club, Kidney, Kidney damage, Kidney disease, Kidney function, Liver cirrhosis, Liver disease, Ltration, Ltration rate, Mdrd6, Mdrd6 formula, Natural history, Nephropathy, Other forms, Pathophysiology, Portal hypertension, Refractory ascites, Renal, Renal blood, Renal disease, Renal dysfunction, Renal failure, Renal function, Renal impairment, Renal vasoconstriction, Rifle criteria, Serum creatinine, Southern california, Splanchnic, Summary statements, Syndrome, Systemic circulation, University college london, Urine, Wong.
Abstract
Objectives To propose an improvement on the current classification of renal dysfunction in cirrhosis. Clinicians caring for patients with cirrhosis recognize that the development of renal dysfunction is associated with significant morbidity and mortality. While most cases of renal dysfunction in cirrhosis are functional in nature, developed as a result of changes in haemodynamics, cardiac function, and renal auto-regulation, there is an increasing number of patients with cirrhosis and structural changes in their kidney as a cause of renal dysfunction. Therefore, there is a need for a newer classification to include both functional and structural renal diseases. Design A working party consisting of specialists from multiple disciplines conducted literature search and developed summary statements, incorporating the renal dysfunction classification used in nephrology. These were discussed and revised to produce this proposal. Setting Multi-disciplinary international meeting. Patients None. Interventions Literature search using keywords of cirrhosis, renal dysfunction, acute kidney injury (AKI), chronic kidney injury (CKD), and hepatorenal syndrome. Results Acute kidney injury will include all causes of acute deterioration of renal function as indicated by an increase in serum creatinine of >50% from baseline, or a rise in serum creatinine of ≥26.4µmol/L (≥0.3mg/dL) in <48hours. Chronic renal disease will be defined as an estimated glomerular filtration rate (GFR) of <60ml/min calculated using the Modification of Diet in Renal Disease 6 (MDRD6) formula, recognising that the MDRD6 formula is not perfect for the cirrhotic patients and this may change as improved means of estimating GFR becomes available. Acute on chronic kidney disease will be defined as AKI superimposed on existing chronic renal disease using the above definitions for AKI and CKD. Conclusions Accepting this new classification will allow studies into the epidemiology, incidence, prevalence, natural history and the development of new treatments for these subtypes of renal dysfunction in cirrhosis.
Url:
DOI: 10.1136/gut.2010.236133
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002263
Links to Exploration step
ISTEX:B8FB2AF0C0A4DB8C9B25369EB3919E64CEA3683CLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Working Party proposal for a revised classification system of renal dysfunction in patients with cirrhosis</title><author><name sortKey="Wong, Florence" sort="Wong, Florence" uniqKey="Wong F" first="Florence" last="Wong">Florence Wong</name><affiliation wicri:level="1"><mods:affiliation>Department of Medicine, University of Toronto, Toronto, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medicine, University of Toronto, Toronto</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>E-mail: florence.wong@utoronto.ca</mods:affiliation><country wicri:rule="url">Canada</country></affiliation></author><author><name sortKey="Nadim, Mitra K" sort="Nadim, Mitra K" uniqKey="Nadim M" first="Mitra K" last="Nadim">Mitra K. Nadim</name><affiliation wicri:level="1"><mods:affiliation>Division of Nephrology, University of Southern California, Los Angeles, California, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Nephrology, University of Southern California, Los Angeles, California</wicri:regionArea></affiliation></author><author><name sortKey="Kellum, John A" sort="Kellum, John A" uniqKey="Kellum J" first="John A" last="Kellum">John A. Kellum</name><affiliation wicri:level="1"><mods:affiliation>Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh</wicri:regionArea></affiliation></author><author><name sortKey="Salerno, Francesco" sort="Salerno, Francesco" uniqKey="Salerno F" first="Francesco" last="Salerno">Francesco Salerno</name><affiliation wicri:level="1"><mods:affiliation>Policlinico IRCCS San Donato and Dipartimento di Scienze Medico-Chirurgiche, Università di Milano, Milano, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Policlinico IRCCS San Donato and Dipartimento di Scienze Medico-Chirurgiche, Università di Milano, Milano</wicri:regionArea></affiliation></author><author><name sortKey="Bellomo, Rinaldo" sort="Bellomo, Rinaldo" uniqKey="Bellomo R" first="Rinaldo" last="Bellomo">Rinaldo Bellomo</name><affiliation wicri:level="1"><mods:affiliation>Department of Intensive Care, Austin Health, Melbourne, Victoria, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Intensive Care, Austin Health, Melbourne, Victoria</wicri:regionArea></affiliation></author><author><name sortKey="Gerbes, Alexander" sort="Gerbes, Alexander" uniqKey="Gerbes A" first="Alexander" last="Gerbes">Alexander Gerbes</name><affiliation wicri:level="1"><mods:affiliation>Liver Center Munich, Klinikum München-Grosshadern, Ludwig-Maximilians-Universität München, München, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Liver Center Munich, Klinikum München-Grosshadern, Ludwig-Maximilians-Universität München, München</wicri:regionArea></affiliation></author><author><name sortKey="Angeli, Paolo" sort="Angeli, Paolo" uniqKey="Angeli P" first="Paolo" last="Angeli">Paolo Angeli</name><affiliation wicri:level="1"><mods:affiliation>Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical and Experimental Medicine, University of Padova, Padova</wicri:regionArea></affiliation></author><author><name sortKey="Moreau, Richard" sort="Moreau, Richard" uniqKey="Moreau R" first="Richard" last="Moreau">Richard Moreau</name><affiliation wicri:level="1"><mods:affiliation>Centre de Recherche Biomédicale Bichat-Beaujon, Service d'Hépatologie, Hôpital Beaujon, Clichy, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre de Recherche Biomédicale Bichat-Beaujon, Service d'Hépatologie, Hôpital Beaujon, Clichy</wicri:regionArea></affiliation></author><author><name sortKey="Davenport, Andrew" sort="Davenport, Andrew" uniqKey="Davenport A" first="Andrew" last="Davenport">Andrew Davenport</name><affiliation wicri:level="1"><mods:affiliation>Centre for Nephrology, University College London Medical School, London, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Nephrology, University College London Medical School, London</wicri:regionArea></affiliation></author><author><name sortKey="Jalan, Rajiv" sort="Jalan, Rajiv" uniqKey="Jalan R" first="Rajiv" last="Jalan">Rajiv Jalan</name><affiliation wicri:level="1"><mods:affiliation>Institute of Hepatology, University College London Medical School, London, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Hepatology, University College London Medical School, London</wicri:regionArea></affiliation></author><author><name sortKey="Ronco, Claudio" sort="Ronco, Claudio" uniqKey="Ronco C" first="Claudio" last="Ronco">Claudio Ronco</name><affiliation wicri:level="1"><mods:affiliation>Division of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Vicenza, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Vicenza</wicri:regionArea></affiliation></author><author><name sortKey="Genyk, Yuri" sort="Genyk, Yuri" uniqKey="Genyk Y" first="Yuri" last="Genyk">Yuri Genyk</name><affiliation wicri:level="1"><mods:affiliation>Division of Multiorgan Abdominal Transplantation, University of Southern California, Los Angeles, California, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Multiorgan Abdominal Transplantation, University of Southern California, Los Angeles, California</wicri:regionArea></affiliation></author><author><name sortKey="Arroyo, Vicente" sort="Arroyo, Vicente" uniqKey="Arroyo V" first="Vicente" last="Arroyo">Vicente Arroyo</name><affiliation wicri:level="1"><mods:affiliation>Liver Unit, Institute of Digestive and Metabolic Diseases, Hospital Clinic, University of Barcelona, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Liver Unit, Institute of Digestive and Metabolic Diseases, Hospital Clinic, University of Barcelona</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:B8FB2AF0C0A4DB8C9B25369EB3919E64CEA3683C</idno><date when="2011" year="2011">2011</date><idno type="doi">10.1136/gut.2010.236133</idno><idno type="url">https://api.istex.fr/document/B8FB2AF0C0A4DB8C9B25369EB3919E64CEA3683C/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002263</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002263</idno><idno type="wicri:Area/Istex/Curation">002263</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Working Party proposal for a revised classification system of renal dysfunction in patients with cirrhosis</title><author><name sortKey="Wong, Florence" sort="Wong, Florence" uniqKey="Wong F" first="Florence" last="Wong">Florence Wong</name><affiliation wicri:level="1"><mods:affiliation>Department of Medicine, University of Toronto, Toronto, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medicine, University of Toronto, Toronto</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>E-mail: florence.wong@utoronto.ca</mods:affiliation><country wicri:rule="url">Canada</country></affiliation></author><author><name sortKey="Nadim, Mitra K" sort="Nadim, Mitra K" uniqKey="Nadim M" first="Mitra K" last="Nadim">Mitra K. Nadim</name><affiliation wicri:level="1"><mods:affiliation>Division of Nephrology, University of Southern California, Los Angeles, California, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Nephrology, University of Southern California, Los Angeles, California</wicri:regionArea></affiliation></author><author><name sortKey="Kellum, John A" sort="Kellum, John A" uniqKey="Kellum J" first="John A" last="Kellum">John A. Kellum</name><affiliation wicri:level="1"><mods:affiliation>Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh</wicri:regionArea></affiliation></author><author><name sortKey="Salerno, Francesco" sort="Salerno, Francesco" uniqKey="Salerno F" first="Francesco" last="Salerno">Francesco Salerno</name><affiliation wicri:level="1"><mods:affiliation>Policlinico IRCCS San Donato and Dipartimento di Scienze Medico-Chirurgiche, Università di Milano, Milano, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Policlinico IRCCS San Donato and Dipartimento di Scienze Medico-Chirurgiche, Università di Milano, Milano</wicri:regionArea></affiliation></author><author><name sortKey="Bellomo, Rinaldo" sort="Bellomo, Rinaldo" uniqKey="Bellomo R" first="Rinaldo" last="Bellomo">Rinaldo Bellomo</name><affiliation wicri:level="1"><mods:affiliation>Department of Intensive Care, Austin Health, Melbourne, Victoria, Australia</mods:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Intensive Care, Austin Health, Melbourne, Victoria</wicri:regionArea></affiliation></author><author><name sortKey="Gerbes, Alexander" sort="Gerbes, Alexander" uniqKey="Gerbes A" first="Alexander" last="Gerbes">Alexander Gerbes</name><affiliation wicri:level="1"><mods:affiliation>Liver Center Munich, Klinikum München-Grosshadern, Ludwig-Maximilians-Universität München, München, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Liver Center Munich, Klinikum München-Grosshadern, Ludwig-Maximilians-Universität München, München</wicri:regionArea></affiliation></author><author><name sortKey="Angeli, Paolo" sort="Angeli, Paolo" uniqKey="Angeli P" first="Paolo" last="Angeli">Paolo Angeli</name><affiliation wicri:level="1"><mods:affiliation>Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical and Experimental Medicine, University of Padova, Padova</wicri:regionArea></affiliation></author><author><name sortKey="Moreau, Richard" sort="Moreau, Richard" uniqKey="Moreau R" first="Richard" last="Moreau">Richard Moreau</name><affiliation wicri:level="1"><mods:affiliation>Centre de Recherche Biomédicale Bichat-Beaujon, Service d'Hépatologie, Hôpital Beaujon, Clichy, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre de Recherche Biomédicale Bichat-Beaujon, Service d'Hépatologie, Hôpital Beaujon, Clichy</wicri:regionArea></affiliation></author><author><name sortKey="Davenport, Andrew" sort="Davenport, Andrew" uniqKey="Davenport A" first="Andrew" last="Davenport">Andrew Davenport</name><affiliation wicri:level="1"><mods:affiliation>Centre for Nephrology, University College London Medical School, London, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Nephrology, University College London Medical School, London</wicri:regionArea></affiliation></author><author><name sortKey="Jalan, Rajiv" sort="Jalan, Rajiv" uniqKey="Jalan R" first="Rajiv" last="Jalan">Rajiv Jalan</name><affiliation wicri:level="1"><mods:affiliation>Institute of Hepatology, University College London Medical School, London, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Hepatology, University College London Medical School, London</wicri:regionArea></affiliation></author><author><name sortKey="Ronco, Claudio" sort="Ronco, Claudio" uniqKey="Ronco C" first="Claudio" last="Ronco">Claudio Ronco</name><affiliation wicri:level="1"><mods:affiliation>Division of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Vicenza, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, Vicenza</wicri:regionArea></affiliation></author><author><name sortKey="Genyk, Yuri" sort="Genyk, Yuri" uniqKey="Genyk Y" first="Yuri" last="Genyk">Yuri Genyk</name><affiliation wicri:level="1"><mods:affiliation>Division of Multiorgan Abdominal Transplantation, University of Southern California, Los Angeles, California, USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Multiorgan Abdominal Transplantation, University of Southern California, Los Angeles, California</wicri:regionArea></affiliation></author><author><name sortKey="Arroyo, Vicente" sort="Arroyo, Vicente" uniqKey="Arroyo V" first="Vicente" last="Arroyo">Vicente Arroyo</name><affiliation wicri:level="1"><mods:affiliation>Liver Unit, Institute of Digestive and Metabolic Diseases, Hospital Clinic, University of Barcelona, Spain</mods:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Liver Unit, Institute of Digestive and Metabolic Diseases, Hospital Clinic, University of Barcelona</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Gut</title><title level="j" type="abbrev">Gut</title><idno type="ISSN">0017-5749</idno><idno type="eISSN">1468-3288</idno><imprint><publisher>BMJ Publishing Group Ltd and British Society of Gastroenterology</publisher><date type="published" when="2011-05">2011-05</date><biblScope unit="volume">60</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="702">702</biblScope></imprint><idno type="ISSN">0017-5749</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0017-5749</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acute deterioration</term><term>Acute dialysis quality initiative</term><term>Acute kidney injury</term><term>Acute kidney injury network</term><term>Adqi</term><term>Ascites</term><term>Baseline</term><term>Cardiac</term><term>Cardiac output</term><term>Chronic kidney disease</term><term>Cirrhosis</term><term>Cirrhotic</term><term>Cirrhotic patients</term><term>Creatinine</term><term>Creatinine clearance</term><term>Decompensated cirrhosis</term><term>Diagnostic criteria</term><term>Dysfunction</term><term>Glomerular</term><term>Hepatology</term><term>Hepatorenal</term><term>Hepatorenal syndrome</term><term>Hyperdynamic circulation</term><term>Hypertension</term><term>Intensive care</term><term>International ascites club</term><term>Kidney</term><term>Kidney damage</term><term>Kidney disease</term><term>Kidney function</term><term>Liver cirrhosis</term><term>Liver disease</term><term>Ltration</term><term>Ltration rate</term><term>Mdrd6</term><term>Mdrd6 formula</term><term>Natural history</term><term>Nephropathy</term><term>Other forms</term><term>Pathophysiology</term><term>Portal hypertension</term><term>Refractory ascites</term><term>Renal</term><term>Renal blood</term><term>Renal disease</term><term>Renal dysfunction</term><term>Renal failure</term><term>Renal function</term><term>Renal impairment</term><term>Renal vasoconstriction</term><term>Rifle criteria</term><term>Serum creatinine</term><term>Southern california</term><term>Splanchnic</term><term>Summary statements</term><term>Syndrome</term><term>Systemic circulation</term><term>University college london</term><term>Urine</term><term>Wong</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Acute deterioration</term><term>Acute dialysis quality initiative</term><term>Acute kidney injury</term><term>Acute kidney injury network</term><term>Adqi</term><term>Ascites</term><term>Baseline</term><term>Cardiac</term><term>Cardiac output</term><term>Chronic kidney disease</term><term>Cirrhosis</term><term>Cirrhotic</term><term>Cirrhotic patients</term><term>Creatinine</term><term>Creatinine clearance</term><term>Decompensated cirrhosis</term><term>Diagnostic criteria</term><term>Dysfunction</term><term>Glomerular</term><term>Hepatology</term><term>Hepatorenal</term><term>Hepatorenal syndrome</term><term>Hyperdynamic circulation</term><term>Hypertension</term><term>Intensive care</term><term>International ascites club</term><term>Kidney</term><term>Kidney damage</term><term>Kidney disease</term><term>Kidney function</term><term>Liver cirrhosis</term><term>Liver disease</term><term>Ltration</term><term>Ltration rate</term><term>Mdrd6</term><term>Mdrd6 formula</term><term>Natural history</term><term>Nephropathy</term><term>Other forms</term><term>Pathophysiology</term><term>Portal hypertension</term><term>Refractory ascites</term><term>Renal</term><term>Renal blood</term><term>Renal disease</term><term>Renal dysfunction</term><term>Renal failure</term><term>Renal function</term><term>Renal impairment</term><term>Renal vasoconstriction</term><term>Rifle criteria</term><term>Serum creatinine</term><term>Southern california</term><term>Splanchnic</term><term>Summary statements</term><term>Syndrome</term><term>Systemic circulation</term><term>University college london</term><term>Urine</term><term>Wong</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Maladie rénale</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Objectives To propose an improvement on the current classification of renal dysfunction in cirrhosis. Clinicians caring for patients with cirrhosis recognize that the development of renal dysfunction is associated with significant morbidity and mortality. While most cases of renal dysfunction in cirrhosis are functional in nature, developed as a result of changes in haemodynamics, cardiac function, and renal auto-regulation, there is an increasing number of patients with cirrhosis and structural changes in their kidney as a cause of renal dysfunction. Therefore, there is a need for a newer classification to include both functional and structural renal diseases. Design A working party consisting of specialists from multiple disciplines conducted literature search and developed summary statements, incorporating the renal dysfunction classification used in nephrology. These were discussed and revised to produce this proposal. Setting Multi-disciplinary international meeting. Patients None. Interventions Literature search using keywords of cirrhosis, renal dysfunction, acute kidney injury (AKI), chronic kidney injury (CKD), and hepatorenal syndrome. Results Acute kidney injury will include all causes of acute deterioration of renal function as indicated by an increase in serum creatinine of >50% from baseline, or a rise in serum creatinine of ≥26.4µmol/L (≥0.3mg/dL) in <48hours. Chronic renal disease will be defined as an estimated glomerular filtration rate (GFR) of <60ml/min calculated using the Modification of Diet in Renal Disease 6 (MDRD6) formula, recognising that the MDRD6 formula is not perfect for the cirrhotic patients and this may change as improved means of estimating GFR becomes available. Acute on chronic kidney disease will be defined as AKI superimposed on existing chronic renal disease using the above definitions for AKI and CKD. Conclusions Accepting this new classification will allow studies into the epidemiology, incidence, prevalence, natural history and the development of new treatments for these subtypes of renal dysfunction in cirrhosis.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Istex/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002263 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Curation/biblio.hfd -nk 002263 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Istex
|étape= Curation
|type= RBID
|clé= ISTEX:B8FB2AF0C0A4DB8C9B25369EB3919E64CEA3683C
|texte= Working Party proposal for a revised classification system of renal dysfunction in patients with cirrhosis
}}
| This area was generated with Dilib version V0.6.33. |  |