An international case-control study on hypospadias the problem with variability and the beauty of diversity
Identifieur interne : 000A34 ( Istex/Curation ); précédent : 000A33; suivant : 000A35An international case-control study on hypospadias the problem with variability and the beauty of diversity
Auteurs : B. K Llén [Suède] ; E. E. Castilla [Argentine] ; E. Robert [France] ; P. A. L. Lancaster [Australie] ; M. Kringelbach [Danemark] ; O. Mutchinick [Mexique] ; M. L. Martinez-Frias [Espagne] ; P. Mastroiacovo [Italie]Source :
- European Journal of Epidemiology [ 0393-2990 ] ; 1992-03-01.
Descripteurs français
- Wicri :
- geographic : Danemark, Espagne.
- topic : Avortement.
English descriptors
- KwdEn :
- Abortion, Anticonvulsant drugs, Available evidence, Bias, Birth defect, Birth defects, Blank questionnaires, Cent smoking, Confidence intervals, Congenital malformations, Defect, Denmark, Different populations, Discordant pairs, Drug usage, Exogenous hormones, Fertility problems, Formative period, France italy mexico, Hormone exposure, Hormone therapy, Hormone treatment, Hypospadias, Increase numbers, International clearinghouse, International study, Interviewer, Interviewer bias, Italian rate, Joint study, Large number, Main purpose, Malformation, Mastroiacovo, Maternal occupation, Multicenter study, Odds ratio, Odds ratios, Other programs, Other studies, Parental subfertility, Pregnancy, Pregnancy support, Present study, Previous pregnancies, Previous pregnancy, Previous spont, Same person, Same time, Sensitive period, Spain, Specific exposures, Spontaneous abortions, Standard errors, Such bias, Tract infection.
- Teeft :
- Abortion, Anticonvulsant drugs, Available evidence, Bias, Birth defect, Birth defects, Blank questionnaires, Cent smoking, Confidence intervals, Congenital malformations, Defect, Denmark, Different populations, Discordant pairs, Drug usage, Exogenous hormones, Fertility problems, Formative period, France italy mexico, Hormone exposure, Hormone therapy, Hormone treatment, Hypospadias, Increase numbers, International clearinghouse, International study, Interviewer, Interviewer bias, Italian rate, Joint study, Large number, Main purpose, Malformation, Mastroiacovo, Maternal occupation, Multicenter study, Odds ratio, Odds ratios, Other programs, Other studies, Parental subfertility, Pregnancy, Pregnancy support, Present study, Previous pregnancies, Previous pregnancy, Previous spont, Same person, Same time, Sensitive period, Spain, Specific exposures, Spontaneous abortions, Standard errors, Such bias, Tract infection.
Abstract
Abstract: The paper describes problems and advantages in an international cooperative study of a casecontrol design, aimed at investigating the possible association between exogenous hormones and hypospadias. The varying degrees of the ascertainment of specific exposures and risk factors, in spite of the use of a standardized questionnaire is illustrated. Definite support for the existence of recall or interviewer bias is presented. On the other hand, the multipopulation design offers possibilities to make use of the diversity of the populations: differences in reproductive patterns and in specific exposures such as drug use, smoking and maternal occupation.
Url:
DOI: 10.1007/BF00144810
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ISTEX:37BC22B747A9E32E892E606FCB37872B212085EBLe document en format XML
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<term>Bias</term>
<term>Birth defect</term>
<term>Birth defects</term>
<term>Blank questionnaires</term>
<term>Cent smoking</term>
<term>Confidence intervals</term>
<term>Congenital malformations</term>
<term>Defect</term>
<term>Denmark</term>
<term>Different populations</term>
<term>Discordant pairs</term>
<term>Drug usage</term>
<term>Exogenous hormones</term>
<term>Fertility problems</term>
<term>Formative period</term>
<term>France italy mexico</term>
<term>Hormone exposure</term>
<term>Hormone therapy</term>
<term>Hormone treatment</term>
<term>Hypospadias</term>
<term>Increase numbers</term>
<term>International clearinghouse</term>
<term>International study</term>
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<term>Joint study</term>
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<term>Mastroiacovo</term>
<term>Maternal occupation</term>
<term>Multicenter study</term>
<term>Odds ratio</term>
<term>Odds ratios</term>
<term>Other programs</term>
<term>Other studies</term>
<term>Parental subfertility</term>
<term>Pregnancy</term>
<term>Pregnancy support</term>
<term>Present study</term>
<term>Previous pregnancies</term>
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<term>Birth defects</term>
<term>Blank questionnaires</term>
<term>Cent smoking</term>
<term>Confidence intervals</term>
<term>Congenital malformations</term>
<term>Defect</term>
<term>Denmark</term>
<term>Different populations</term>
<term>Discordant pairs</term>
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<term>Exogenous hormones</term>
<term>Fertility problems</term>
<term>Formative period</term>
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<term>Hormone therapy</term>
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<term>International clearinghouse</term>
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<term>Interviewer bias</term>
<term>Italian rate</term>
<term>Joint study</term>
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<term>Main purpose</term>
<term>Malformation</term>
<term>Mastroiacovo</term>
<term>Maternal occupation</term>
<term>Multicenter study</term>
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<term>Pregnancy support</term>
<term>Present study</term>
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<term>Previous pregnancy</term>
<term>Previous spont</term>
<term>Same person</term>
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<term>Such bias</term>
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<front><div type="abstract" xml:lang="en">Abstract: The paper describes problems and advantages in an international cooperative study of a casecontrol design, aimed at investigating the possible association between exogenous hormones and hypospadias. The varying degrees of the ascertainment of specific exposures and risk factors, in spite of the use of a standardized questionnaire is illustrated. Definite support for the existence of recall or interviewer bias is presented. On the other hand, the multipopulation design offers possibilities to make use of the diversity of the populations: differences in reproductive patterns and in specific exposures such as drug use, smoking and maternal occupation.</div>
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