Differing actions of β-(2-thienyl)-γ-aminobutyric acid in central and peripheral preparations
Identifieur interne : 002516 ( Istex/Corpus ); précédent : 002515; suivant : 002517Differing actions of β-(2-thienyl)-γ-aminobutyric acid in central and peripheral preparations
Auteurs : Jennifer Ong ; David I. B. Kerr ; Pascal Berthelot ; Claude Vaccher ; Nathalie Flouquet ; Michel DebaertSource :
- European Journal of Pharmacology [ 0014-2999 ] ; 1992.
English descriptors
- KwdEn :
- Agonist, Agonist activity, Agonists wcrc, Analogue, Antagonist, Baclofen, Berthelot, Control level, Different preparations, Full agonist, Gaba, Ileum, Krebs medium, Krebs solution, Neocortical slices, Partial agonism, Partial agonist, Phenyl ring, Present study, Receptor, Receptor agonist, Receptor antagonist, Receptor antagonists, Spontaneous activity, Spontaneous discharges.
- Teeft :
- Agonist, Agonist activity, Agonists wcrc, Analogue, Antagonist, Baclofen, Berthelot, Control level, Different preparations, Full agonist, Gaba, Ileum, Krebs medium, Krebs solution, Neocortical slices, Partial agonism, Partial agonist, Phenyl ring, Present study, Receptor, Receptor agonist, Receptor antagonist, Receptor antagonists, Spontaneous activity, Spontaneous discharges.
Abstract
Abstract: In the guinea-pig isolated ileum, β-(2-thicnyI)-γ-aminobutyric acid (BTG; 100–500 μM reversibly and competitively (pA2 = 4.3 ± 0.1) antagonised the baclofen-induccd (5–100 μM) depression of cholinergic twitch contractions, but not that to adenosine or morphine. By contrast, in rat neocortical slice preparations, BTG (100–500 μM) acted as an agonist, abolishing the frequency and amplitude of spontaneous discharges, sensitive to 2-hydroxysaclofen (100–500 μM). BTG exhibits differential actions at G ABAB receptors in brain and periphery.
Url:
DOI: 10.1016/0014-2999(92)90784-2
Links to Exploration step
ISTEX:C81244B2BA40632FA881487CBC18CD35AA5D6938Le document en format XML
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Kerr</name><affiliation><mods:affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</mods:affiliation></affiliation></author><author><name sortKey="Berthelot, Pascal" sort="Berthelot, Pascal" uniqKey="Berthelot P" first="Pascal" last="Berthelot">Pascal Berthelot</name><affiliation><mods:affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</mods:affiliation></affiliation></author><author><name sortKey="Vaccher, Claude" sort="Vaccher, Claude" uniqKey="Vaccher C" first="Claude" last="Vaccher">Claude Vaccher</name><affiliation><mods:affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</mods:affiliation></affiliation></author><author><name sortKey="Flouquet, Nathalie" sort="Flouquet, Nathalie" uniqKey="Flouquet N" first="Nathalie" last="Flouquet">Nathalie Flouquet</name><affiliation><mods:affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</mods:affiliation></affiliation></author><author><name sortKey="Debaert, Michel" sort="Debaert, Michel" uniqKey="Debaert M" first="Michel" last="Debaert">Michel Debaert</name><affiliation><mods:affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">European Journal of Pharmacology</title><title level="j" type="abbrev">EJP</title><idno type="ISSN">0014-2999</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1992">1992</date><biblScope unit="volume">221</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="145">145</biblScope><biblScope unit="page" to="149">149</biblScope></imprint><idno type="ISSN">0014-2999</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0014-2999</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Agonist</term><term>Agonist activity</term><term>Agonists wcrc</term><term>Analogue</term><term>Antagonist</term><term>Baclofen</term><term>Berthelot</term><term>Control level</term><term>Different preparations</term><term>Full agonist</term><term>Gaba</term><term>Ileum</term><term>Krebs medium</term><term>Krebs solution</term><term>Neocortical slices</term><term>Partial agonism</term><term>Partial agonist</term><term>Phenyl ring</term><term>Present study</term><term>Receptor</term><term>Receptor agonist</term><term>Receptor antagonist</term><term>Receptor antagonists</term><term>Spontaneous activity</term><term>Spontaneous discharges</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Agonist</term><term>Agonist activity</term><term>Agonists wcrc</term><term>Analogue</term><term>Antagonist</term><term>Baclofen</term><term>Berthelot</term><term>Control level</term><term>Different preparations</term><term>Full agonist</term><term>Gaba</term><term>Ileum</term><term>Krebs medium</term><term>Krebs solution</term><term>Neocortical slices</term><term>Partial agonism</term><term>Partial agonist</term><term>Phenyl ring</term><term>Present study</term><term>Receptor</term><term>Receptor agonist</term><term>Receptor antagonist</term><term>Receptor antagonists</term><term>Spontaneous activity</term><term>Spontaneous discharges</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: In the guinea-pig isolated ileum, β-(2-thicnyI)-γ-aminobutyric acid (BTG; 100–500 μM reversibly and competitively (pA2 = 4.3 ± 0.1) antagonised the baclofen-induccd (5–100 μM) depression of cholinergic twitch contractions, but not that to adenosine or morphine. By contrast, in rat neocortical slice preparations, BTG (100–500 μM) acted as an agonist, abolishing the frequency and amplitude of spontaneous discharges, sensitive to 2-hydroxysaclofen (100–500 μM). BTG exhibits differential actions at G ABAB receptors in brain and periphery.</div></front></TEI><istex><corpusName>elsevier</corpusName><keywords><teeft><json:string>agonist</json:string><json:string>gaba</json:string><json:string>receptor</json:string><json:string>baclofen</json:string><json:string>berthelot</json:string><json:string>ileum</json:string><json:string>spontaneous discharges</json:string><json:string>spontaneous activity</json:string><json:string>partial agonist</json:string><json:string>analogue</json:string><json:string>antagonist</json:string><json:string>phenyl ring</json:string><json:string>krebs solution</json:string><json:string>full agonist</json:string><json:string>different preparations</json:string><json:string>neocortical slices</json:string><json:string>krebs medium</json:string><json:string>agonists wcrc</json:string><json:string>agonist activity</json:string><json:string>control level</json:string><json:string>receptor antagonist</json:string><json:string>receptor antagonists</json:string><json:string>partial agonism</json:string><json:string>present study</json:string><json:string>receptor agonist</json:string></teeft></keywords><author><json:item><name>Jennifer Ong</name><affiliations><json:string>Department of Anaesthesia and Intensive Care, The University of Adelaide, Adelaide, South Australia 5000, Australia</json:string><json:string>Correspondence to: J. Ong, Department of Anaesthesia and Intensive Care, The University of Adelaide, Adelaide, South Australia 5000. Australia. Tel. 61 (8) 228-5163, fax 61 (8) 232-3283.</json:string></affiliations></json:item><json:item><name>David I.B. Kerr</name><affiliations><json:string>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</json:string></affiliations></json:item><json:item><name>Pascal Berthelot</name><affiliations><json:string>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</json:string></affiliations></json:item><json:item><name>Claude Vaccher</name><affiliations><json:string>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</json:string></affiliations></json:item><json:item><name>Nathalie Flouquet</name><affiliations><json:string>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</json:string></affiliations></json:item><json:item><name>Michel Debaert</name><affiliations><json:string>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>β-(2-Thienyl)-GABA</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Baclofen</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Ileum (guinea-pig, isolated)</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Neocortical slices</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>(rat)</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>2-Hydroxysaclofen</value></json:item></subject><arkIstex>ark:/67375/6H6-J4KVZ3VW-5</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>Short communication</json:string></originalGenre><abstract>Abstract: In the guinea-pig isolated ileum, β-(2-thicnyI)-γ-aminobutyric acid (BTG; 100–500 μM reversibly and competitively (pA2 = 4.3 ± 0.1) antagonised the baclofen-induccd (5–100 μM) depression of cholinergic twitch contractions, but not that to adenosine or morphine. By contrast, in rat neocortical slice preparations, BTG (100–500 μM) acted as an agonist, abolishing the frequency and amplitude of spontaneous discharges, sensitive to 2-hydroxysaclofen (100–500 μM). BTG exhibits differential actions at G ABAB receptors in brain and periphery.</abstract><qualityIndicators><score>5.07</score><pdfWordCount>2170</pdfWordCount><pdfCharCount>15157</pdfCharCount><pdfVersion>1.2</pdfVersion><pdfPageCount>5</pdfPageCount><pdfPageSize>576 x 756 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractWordCount>75</abstractWordCount><abstractCharCount>550</abstractCharCount><keywordCount>6</keywordCount></qualityIndicators><title>Differing actions of β-(2-thienyl)-γ-aminobutyric acid in central and peripheral preparations</title><pmid><json:string>1333970</json:string></pmid><pii><json:string>0014-2999(92)90784-2</json:string></pii><genre><json:string>brief-communication</json:string></genre><host><title>European Journal of Pharmacology</title><language><json:string>unknown</json:string></language><publicationDate>1992</publicationDate><issn><json:string>0014-2999</json:string></issn><pii><json:string>S0014-2999(00)X1039-4</json:string></pii><volume>221</volume><issue>1</issue><pages><first>145</first><last>149</last></pages><genre><json:string>journal</json:string></genre></host><namedEntities><unitex><date><json:string>1992</json:string><json:string>1902</json:string></date><geogName></geogName><orgName><json:string>Australian Research Council Rcscarch Fellowship</json:string><json:string>Flinders University</json:string></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName><json:string>Claude Vaccher</json:string><json:string>J. Ons</json:string><json:string>R.H. 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Ong, Department of Anaesthesia and Intensive Care, The University of Adelaide, Adelaide, South Australia 5000. Australia. Tel. 61 (8) 228-5163, fax 61 (8) 232-3283.</affiliation></author><author xml:id="author-0001"><persName><forename type="first">David I.B.</forename><surname>Kerr</surname></persName><affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</affiliation></author><author xml:id="author-0002"><persName><forename type="first">Pascal</forename><surname>Berthelot</surname></persName><affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</affiliation></author><author xml:id="author-0003"><persName><forename type="first">Claude</forename><surname>Vaccher</surname></persName><affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</affiliation></author><author xml:id="author-0004"><persName><forename type="first">Nathalie</forename><surname>Flouquet</surname></persName><affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</affiliation></author><author xml:id="author-0005"><persName><forename type="first">Michel</forename><surname>Debaert</surname></persName><affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</affiliation></author><idno type="istex">C81244B2BA40632FA881487CBC18CD35AA5D6938</idno><idno type="DOI">10.1016/0014-2999(92)90784-2</idno><idno type="PII">0014-2999(92)90784-2</idno></analytic><monogr><title level="j">European Journal of Pharmacology</title><title level="j" type="abbrev">EJP</title><idno type="pISSN">0014-2999</idno><idno type="PII">S0014-2999(00)X1039-4</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1992"></date><biblScope unit="volume">221</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="145">145</biblScope><biblScope unit="page" to="149">149</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1992</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>In the guinea-pig isolated ileum, β-(2-thicnyI)-γ-aminobutyric acid (BTG; 100–500 μM reversibly and competitively (pA2 = 4.3 ± 0.1) antagonised the baclofen-induccd (5–100 μM) depression of cholinergic twitch contractions, but not that to adenosine or morphine. By contrast, in rat neocortical slice preparations, BTG (100–500 μM) acted as an agonist, abolishing the frequency and amplitude of spontaneous discharges, sensitive to 2-hydroxysaclofen (100–500 μM). BTG exhibits differential actions at G ABAB receptors in brain and periphery.</p></abstract><textClass><keywords scheme="keyword"><list><head>Keywords</head><item><term>β-(2-Thienyl)-GABA</term></item><item><term>Baclofen</term></item><item><term>Ileum (guinea-pig, isolated)</term></item><item><term>Neocortical slices</term></item><item><term>(rat)</term></item><item><term>2-Hydroxysaclofen</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1992-07-29">Modified</change><change when="1992">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/C81244B2BA40632FA881487CBC18CD35AA5D6938/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: tail"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" </istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="sco"><item-info><jid>EJP</jid><aid>90784</aid><ce:pii>0014-2999(92)90784-2</ce:pii><ce:doi>10.1016/0014-2999(92)90784-2</ce:doi><ce:copyright type="unknown" year="1992"></ce:copyright></item-info><head><ce:dochead><ce:textfn>Short communication</ce:textfn></ce:dochead><ce:title>Differing actions of β-(2-thienyl)-γ-aminobutyric acid in central and peripheral preparations</ce:title><ce:author-group><ce:author><ce:given-name>Jennifer</ce:given-name><ce:surname>Ong</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>∗</ce:sup></ce:cross-ref><ce:cross-ref refid="COR1"><ce:sup>∗</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>David I.B.</ce:given-name><ce:surname>Kerr</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>a</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Pascal</ce:given-name><ce:surname>Berthelot</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>a</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Claude</ce:given-name><ce:surname>Vaccher</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>a</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Nathalie</ce:given-name><ce:surname>Flouquet</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>a</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Michel</ce:given-name><ce:surname>Debaert</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>a</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="AFF1"><ce:label>∗</ce:label><ce:textfn>Department of Anaesthesia and Intensive Care, The University of Adelaide, Adelaide, South Australia 5000, Australia</ce:textfn></ce:affiliation><ce:affiliation id="AFF2"><ce:label>a</ce:label><ce:textfn>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</ce:textfn></ce:affiliation><ce:correspondence id="COR1"><ce:label>∗</ce:label><ce:text>Correspondence to: J. Ong, Department of Anaesthesia and Intensive Care, The University of Adelaide, Adelaide, South Australia 5000. Australia. Tel. 61 (8) 228-5163, fax 61 (8) 232-3283.</ce:text></ce:correspondence></ce:author-group><ce:date-received day="1" month="6" year="1992"></ce:date-received><ce:date-revised day="29" month="7" year="1992"></ce:date-revised><ce:date-accepted day="4" month="8" year="1992"></ce:date-accepted><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para id="SP0005">In the guinea-pig isolated ileum, β-(2-thicnyI)-γ-aminobutyric acid (BTG; 100–500 μM reversibly and competitively (pA<ce:inf>2</ce:inf> = 4.3 ± 0.1) antagonised the baclofen-induccd (5–100 μM) depression of cholinergic twitch contractions, but not that to adenosine or morphine. By contrast, in rat neocortical slice preparations, BTG (100–500 μM) acted as an agonist, abolishing the frequency and amplitude of spontaneous discharges, sensitive to 2-hydroxysaclofen (100–500 μM). BTG exhibits differential actions at G ABA<ce:inf>B</ce:inf> receptors in brain and periphery.</ce:simple-para></ce:abstract-sec></ce:abstract><ce:keywords><ce:section-title>Keywords</ce:section-title><ce:keyword><ce:text>β-(2-Thienyl)-GABA</ce:text></ce:keyword><ce:keyword><ce:text>Baclofen</ce:text></ce:keyword><ce:keyword><ce:text>Ileum (guinea-pig, isolated)</ce:text></ce:keyword><ce:keyword><ce:text>Neocortical slices</ce:text></ce:keyword><ce:keyword><ce:text>(rat)</ce:text></ce:keyword><ce:keyword><ce:text>2-Hydroxysaclofen</ce:text></ce:keyword></ce:keywords></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Differing actions of β-(2-thienyl)-γ-aminobutyric acid in central and peripheral preparations</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Differing actions of β-(2-thienyl)-γ-aminobutyric acid in central and peripheral preparations</title></titleInfo><name type="personal"><namePart type="given">Jennifer</namePart><namePart type="family">Ong</namePart><affiliation>Department of Anaesthesia and Intensive Care, The University of Adelaide, Adelaide, South Australia 5000, Australia</affiliation><affiliation>Correspondence to: J. Ong, Department of Anaesthesia and Intensive Care, The University of Adelaide, Adelaide, South Australia 5000. Australia. Tel. 61 (8) 228-5163, fax 61 (8) 232-3283.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">David I.B.</namePart><namePart type="family">Kerr</namePart><affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Pascal</namePart><namePart type="family">Berthelot</namePart><affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Claude</namePart><namePart type="family">Vaccher</namePart><affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Nathalie</namePart><namePart type="family">Flouquet</namePart><affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Michel</namePart><namePart type="family">Debaert</namePart><affiliation>Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Lille, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="brief-communication" displayLabel="Short communication" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-S9SX2MFS-0">brief-communication</genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1992</dateIssued><dateModified encoding="w3cdtf">1992-07-29</dateModified><copyrightDate encoding="w3cdtf">1992</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><abstract lang="en">Abstract: In the guinea-pig isolated ileum, β-(2-thicnyI)-γ-aminobutyric acid (BTG; 100–500 μM reversibly and competitively (pA2 = 4.3 ± 0.1) antagonised the baclofen-induccd (5–100 μM) depression of cholinergic twitch contractions, but not that to adenosine or morphine. By contrast, in rat neocortical slice preparations, BTG (100–500 μM) acted as an agonist, abolishing the frequency and amplitude of spontaneous discharges, sensitive to 2-hydroxysaclofen (100–500 μM). BTG exhibits differential actions at G ABAB receptors in brain and periphery.</abstract><note type="content">Section title: Short communication</note><subject><genre>Keywords</genre><topic>β-(2-Thienyl)-GABA</topic><topic>Baclofen</topic><topic>Ileum (guinea-pig, isolated)</topic><topic>Neocortical slices</topic><topic>(rat)</topic><topic>2-Hydroxysaclofen</topic></subject><relatedItem type="host"><titleInfo><title>European Journal of Pharmacology</title></titleInfo><titleInfo type="abbreviated"><title>EJP</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">19921006</dateIssued></originInfo><identifier type="ISSN">0014-2999</identifier><identifier type="PII">S0014-2999(00)X1039-4</identifier><part><date>19921006</date><detail type="volume"><number>221</number><caption>vol.</caption></detail><detail type="issue"><number>1</number><caption>no.</caption></detail><extent unit="issue-pages"><start>1</start><end>184</end></extent><extent unit="pages"><start>145</start><end>149</end></extent></part></relatedItem><identifier type="istex">C81244B2BA40632FA881487CBC18CD35AA5D6938</identifier><identifier type="ark">ark:/67375/6H6-J4KVZ3VW-5</identifier><identifier type="DOI">10.1016/0014-2999(92)90784-2</identifier><identifier type="PII">0014-2999(92)90784-2</identifier><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-HKKZVM7B-M">elsevier</recordContentSource></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/C81244B2BA40632FA881487CBC18CD35AA5D6938/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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