Origins of the glycinergic inputs to the rat locus coeruleus and dorsal raphe nuclei: a study combining retrograde tracing with glycine immunohistochemistry
Identifieur interne : 000504 ( Istex/Corpus ); précédent : 000503; suivant : 000505Origins of the glycinergic inputs to the rat locus coeruleus and dorsal raphe nuclei: a study combining retrograde tracing with glycine immunohistochemistry
Auteurs : Claire Rampon ; Christelle Peyron ; Damien Gervasoni ; David V. Pow ; Pierre-Hervé Luppi ; Patrice FortSource :
- European Journal of Neuroscience [ 0953-816X ] ; 1999-03.
English descriptors
- KwdEn :
- Aghajanian, Anaesthetized rats, Brainstem, Cell bodies, Coeruleus, Contralateral, Dorsal, Dorsal raphe, Dorsal raphe nuclei, Dorsal raphe nucleus, Dpgi, Dpme, Electrophysiological, Ennis, European journal, European neuroscience association, Gaba, Gabaergic, Gigantocellular, Glutamate, Glycine, Glycine immunohistochemistry, Glycinergic, Glycinergic innervation, Glycinergic inputs, Glycinergic neurons, Immunocytochemical, Immunohistochemistry, Injection cases, Injection sites, Innervation, Ipsilateral, Large number, Largest number, Lateral, Lateral paragigantocellular nucleus, Lesser degree, Locus, Locus coeruleus, Locus coeruleus neurones, Lpgi, Luppi, Medulla, Medullary, Mesencephalic, Mesencephalic reticular nucleus, Moderate proportion, Monoaminergic, Monoaminergic neurons, Monoaminergic nuclei, More caudally, Neuron, Neurones, Neuroscience, Neurotransmitter, Noradrenergic, Nucleus, Oral part, Paragigantocellular, Pbst, Periaqueductal, Peyron, Pontine, Primary antiserum, Proximal dendrites, Rampon, Raphe, Raphe magnus, Reticular, Retrograde transport, Retrogradely, Room temperature, Rostral, Rostral ventromedial medullary reticular formation, Saint marie, Serotonergic, Serotonergic neurons, Small number, Solitary tract, Spinal, Spinal motoneurons, Substantial number, Superior olivary, Tracer, Trigeminal, Vector labs, Ventral, Ventral part, Ventrolateral, Ventrolateral parts, Ventromedial.
- Teeft :
- Aghajanian, Anaesthetized rats, Brainstem, Cell bodies, Coeruleus, Contralateral, Dorsal, Dorsal raphe, Dorsal raphe nuclei, Dorsal raphe nucleus, Dpgi, Dpme, Electrophysiological, Ennis, European journal, European neuroscience association, Gaba, Gabaergic, Gigantocellular, Glutamate, Glycine, Glycine immunohistochemistry, Glycinergic, Glycinergic innervation, Glycinergic inputs, Glycinergic neurons, Immunocytochemical, Immunohistochemistry, Injection cases, Injection sites, Innervation, Ipsilateral, Large number, Largest number, Lateral, Lateral paragigantocellular nucleus, Lesser degree, Locus, Locus coeruleus, Locus coeruleus neurones, Lpgi, Luppi, Medulla, Medullary, Mesencephalic, Mesencephalic reticular nucleus, Moderate proportion, Monoaminergic, Monoaminergic neurons, Monoaminergic nuclei, More caudally, Neuron, Neurones, Neuroscience, Neurotransmitter, Noradrenergic, Nucleus, Oral part, Paragigantocellular, Pbst, Periaqueductal, Peyron, Pontine, Primary antiserum, Proximal dendrites, Rampon, Raphe, Raphe magnus, Reticular, Retrograde transport, Retrogradely, Room temperature, Rostral, Rostral ventromedial medullary reticular formation, Saint marie, Serotonergic, Serotonergic neurons, Small number, Solitary tract, Spinal, Spinal motoneurons, Substantial number, Superior olivary, Tracer, Trigeminal, Vector labs, Ventral, Ventral part, Ventrolateral, Ventrolateral parts, Ventromedial.
Abstract
The amino acid glycine is a major inhibitory neurotransmitter in the brainstem and is likely involved in the tonic inhibition of the monoaminergic neurons during all sleep‐waking stages. In order to determine the neurons at the origin of the glycinergic innervation of the two principal monoaminergic nuclei, the locus coeruleus and the dorsal raphe of the rat, we applied a double‐labelling technique, combining retrograde transport of cholera‐toxin B subunit with glycine immunohistochemistry. Using this technique, we found that the locus coeruleus and dorsal raphe nuclei receive a common glycinergic innervation from the ventral and ventrolateral periaqueductal grey, including the adjacent deep mesencephalic reticular nucleus. Small additional glycinergic inputs to these nuclei originated from the lateral paragigantocellular nucleus and the rostral ventromedial medullary reticular formation. The potential role of these glycinergic inputs in the control of the excitability of the monoaminergic neurons of the locus coeruleus and dorsal raphe nuclei is discussed.
Url:
DOI: 10.1046/j.1460-9568.1999.00511.x
Links to Exploration step
ISTEX:1A74E7E0146DD78C5305A1848EB37FA363EC7C7ELe document en format XML
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Pow</name><affiliation><mods:affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Vision, Touch and Hearing Research Center, University of Queensland, Brisbane, Australia</mods:affiliation></affiliation></author><author><name sortKey="Luppi, Pierre Erve" sort="Luppi, Pierre Erve" uniqKey="Luppi P" first="Pierre-Hervé" last="Luppi">Pierre-Hervé Luppi</name><affiliation><mods:affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Fort, Patrice" sort="Fort, Patrice" uniqKey="Fort P" first="Patrice" last="Fort">Patrice Fort</name><affiliation><mods:affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:1A74E7E0146DD78C5305A1848EB37FA363EC7C7E</idno><date when="1999" year="1999">1999</date><idno type="doi">10.1046/j.1460-9568.1999.00511.x</idno><idno type="url">https://api.istex.fr/document/1A74E7E0146DD78C5305A1848EB37FA363EC7C7E/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000504</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000504</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Origins of the glycinergic inputs to the rat locus coeruleus and dorsal raphe nuclei: a study combining retrograde tracing with glycine immunohistochemistry</title><author><name sortKey="Rampon, Claire" sort="Rampon, Claire" uniqKey="Rampon C" first="Claire" last="Rampon">Claire Rampon</name><affiliation><mods:affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Peyron, Christelle" sort="Peyron, Christelle" uniqKey="Peyron C" first="Christelle" last="Peyron">Christelle Peyron</name><affiliation><mods:affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Gervasoni, Damien" sort="Gervasoni, Damien" uniqKey="Gervasoni D" first="Damien" last="Gervasoni">Damien Gervasoni</name><affiliation><mods:affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Pow, David V" sort="Pow, David V" uniqKey="Pow D" first="David V." last="Pow">David V. Pow</name><affiliation><mods:affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Vision, Touch and Hearing Research Center, University of Queensland, Brisbane, Australia</mods:affiliation></affiliation></author><author><name sortKey="Luppi, Pierre Erve" sort="Luppi, Pierre Erve" uniqKey="Luppi P" first="Pierre-Hervé" last="Luppi">Pierre-Hervé Luppi</name><affiliation><mods:affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</mods:affiliation></affiliation></author><author><name sortKey="Fort, Patrice" sort="Fort, Patrice" uniqKey="Fort P" first="Patrice" last="Fort">Patrice Fort</name><affiliation><mods:affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">European Journal of Neuroscience</title><title level="j" type="alt">EUROPEAN JOURNAL OF NEUROSCIENCE</title><idno type="ISSN">0953-816X</idno><idno type="eISSN">1460-9568</idno><imprint><biblScope unit="vol">11</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="1058">1058</biblScope><biblScope unit="page" to="1066">1066</biblScope><biblScope unit="page-count">9</biblScope><publisher>Blackwell Science Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1999-03">1999-03</date></imprint><idno type="ISSN">0953-816X</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0953-816X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aghajanian</term><term>Anaesthetized rats</term><term>Brainstem</term><term>Cell bodies</term><term>Coeruleus</term><term>Contralateral</term><term>Dorsal</term><term>Dorsal raphe</term><term>Dorsal raphe nuclei</term><term>Dorsal raphe nucleus</term><term>Dpgi</term><term>Dpme</term><term>Electrophysiological</term><term>Ennis</term><term>European journal</term><term>European neuroscience association</term><term>Gaba</term><term>Gabaergic</term><term>Gigantocellular</term><term>Glutamate</term><term>Glycine</term><term>Glycine immunohistochemistry</term><term>Glycinergic</term><term>Glycinergic innervation</term><term>Glycinergic inputs</term><term>Glycinergic neurons</term><term>Immunocytochemical</term><term>Immunohistochemistry</term><term>Injection cases</term><term>Injection sites</term><term>Innervation</term><term>Ipsilateral</term><term>Large number</term><term>Largest number</term><term>Lateral</term><term>Lateral paragigantocellular nucleus</term><term>Lesser degree</term><term>Locus</term><term>Locus coeruleus</term><term>Locus coeruleus neurones</term><term>Lpgi</term><term>Luppi</term><term>Medulla</term><term>Medullary</term><term>Mesencephalic</term><term>Mesencephalic reticular nucleus</term><term>Moderate proportion</term><term>Monoaminergic</term><term>Monoaminergic neurons</term><term>Monoaminergic nuclei</term><term>More caudally</term><term>Neuron</term><term>Neurones</term><term>Neuroscience</term><term>Neurotransmitter</term><term>Noradrenergic</term><term>Nucleus</term><term>Oral part</term><term>Paragigantocellular</term><term>Pbst</term><term>Periaqueductal</term><term>Peyron</term><term>Pontine</term><term>Primary antiserum</term><term>Proximal dendrites</term><term>Rampon</term><term>Raphe</term><term>Raphe magnus</term><term>Reticular</term><term>Retrograde transport</term><term>Retrogradely</term><term>Room temperature</term><term>Rostral</term><term>Rostral ventromedial medullary reticular formation</term><term>Saint marie</term><term>Serotonergic</term><term>Serotonergic neurons</term><term>Small number</term><term>Solitary tract</term><term>Spinal</term><term>Spinal motoneurons</term><term>Substantial number</term><term>Superior olivary</term><term>Tracer</term><term>Trigeminal</term><term>Vector labs</term><term>Ventral</term><term>Ventral part</term><term>Ventrolateral</term><term>Ventrolateral parts</term><term>Ventromedial</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Aghajanian</term><term>Anaesthetized rats</term><term>Brainstem</term><term>Cell bodies</term><term>Coeruleus</term><term>Contralateral</term><term>Dorsal</term><term>Dorsal raphe</term><term>Dorsal raphe nuclei</term><term>Dorsal raphe nucleus</term><term>Dpgi</term><term>Dpme</term><term>Electrophysiological</term><term>Ennis</term><term>European journal</term><term>European neuroscience association</term><term>Gaba</term><term>Gabaergic</term><term>Gigantocellular</term><term>Glutamate</term><term>Glycine</term><term>Glycine immunohistochemistry</term><term>Glycinergic</term><term>Glycinergic innervation</term><term>Glycinergic inputs</term><term>Glycinergic neurons</term><term>Immunocytochemical</term><term>Immunohistochemistry</term><term>Injection cases</term><term>Injection sites</term><term>Innervation</term><term>Ipsilateral</term><term>Large number</term><term>Largest number</term><term>Lateral</term><term>Lateral paragigantocellular nucleus</term><term>Lesser degree</term><term>Locus</term><term>Locus coeruleus</term><term>Locus coeruleus neurones</term><term>Lpgi</term><term>Luppi</term><term>Medulla</term><term>Medullary</term><term>Mesencephalic</term><term>Mesencephalic reticular nucleus</term><term>Moderate proportion</term><term>Monoaminergic</term><term>Monoaminergic neurons</term><term>Monoaminergic nuclei</term><term>More caudally</term><term>Neuron</term><term>Neurones</term><term>Neuroscience</term><term>Neurotransmitter</term><term>Noradrenergic</term><term>Nucleus</term><term>Oral part</term><term>Paragigantocellular</term><term>Pbst</term><term>Periaqueductal</term><term>Peyron</term><term>Pontine</term><term>Primary antiserum</term><term>Proximal dendrites</term><term>Rampon</term><term>Raphe</term><term>Raphe magnus</term><term>Reticular</term><term>Retrograde transport</term><term>Retrogradely</term><term>Room temperature</term><term>Rostral</term><term>Rostral ventromedial medullary reticular formation</term><term>Saint marie</term><term>Serotonergic</term><term>Serotonergic neurons</term><term>Small number</term><term>Solitary tract</term><term>Spinal</term><term>Spinal motoneurons</term><term>Substantial number</term><term>Superior olivary</term><term>Tracer</term><term>Trigeminal</term><term>Vector labs</term><term>Ventral</term><term>Ventral part</term><term>Ventrolateral</term><term>Ventrolateral parts</term><term>Ventromedial</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The amino acid glycine is a major inhibitory neurotransmitter in the brainstem and is likely involved in the tonic inhibition of the monoaminergic neurons during all sleep‐waking stages. In order to determine the neurons at the origin of the glycinergic innervation of the two principal monoaminergic nuclei, the locus coeruleus and the dorsal raphe of the rat, we applied a double‐labelling technique, combining retrograde transport of cholera‐toxin B subunit with glycine immunohistochemistry. Using this technique, we found that the locus coeruleus and dorsal raphe nuclei receive a common glycinergic innervation from the ventral and ventrolateral periaqueductal grey, including the adjacent deep mesencephalic reticular nucleus. Small additional glycinergic inputs to these nuclei originated from the lateral paragigantocellular nucleus and the rostral ventromedial medullary reticular formation. The potential role of these glycinergic inputs in the control of the excitability of the monoaminergic neurons of the locus coeruleus and dorsal raphe nuclei is discussed.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>glycine</json:string><json:string>glycinergic</json:string><json:string>neuroscience</json:string><json:string>reticular</json:string><json:string>neuron</json:string><json:string>dorsal</json:string><json:string>raphe</json:string><json:string>coeruleus</json:string><json:string>brainstem</json:string><json:string>periaqueductal</json:string><json:string>ventral</json:string><json:string>locus coeruleus</json:string><json:string>luppi</json:string><json:string>rampon</json:string><json:string>rostral</json:string><json:string>medullary</json:string><json:string>monoaminergic</json:string><json:string>neurones</json:string><json:string>ventrolateral</json:string><json:string>ventromedial</json:string><json:string>mesencephalic</json:string><json:string>glycinergic inputs</json:string><json:string>pontine</json:string><json:string>lpgi</json:string><json:string>spinal</json:string><json:string>lateral</json:string><json:string>ipsilateral</json:string><json:string>medulla</json:string><json:string>paragigantocellular</json:string><json:string>peyron</json:string><json:string>dpme</json:string><json:string>trigeminal</json:string><json:string>immunohistochemistry</json:string><json:string>noradrenergic</json:string><json:string>monoaminergic neurons</json:string><json:string>gaba</json:string><json:string>rostral ventromedial medullary reticular formation</json:string><json:string>gigantocellular</json:string><json:string>ventrolateral parts</json:string><json:string>retrogradely</json:string><json:string>aghajanian</json:string><json:string>tracer</json:string><json:string>gabaergic</json:string><json:string>neurotransmitter</json:string><json:string>pbst</json:string><json:string>dorsal raphe nucleus</json:string><json:string>european journal</json:string><json:string>dorsal raphe</json:string><json:string>european neuroscience association</json:string><json:string>lateral paragigantocellular nucleus</json:string><json:string>glutamate</json:string><json:string>contralateral</json:string><json:string>immunocytochemical</json:string><json:string>electrophysiological</json:string><json:string>serotonergic</json:string><json:string>dpgi</json:string><json:string>innervation</json:string><json:string>locus</json:string><json:string>monoaminergic nuclei</json:string><json:string>cell bodies</json:string><json:string>substantial number</json:string><json:string>largest number</json:string><json:string>room temperature</json:string><json:string>mesencephalic reticular nucleus</json:string><json:string>small number</json:string><json:string>retrograde transport</json:string><json:string>nucleus</json:string><json:string>injection sites</json:string><json:string>anaesthetized rats</json:string><json:string>glycinergic neurons</json:string><json:string>lesser degree</json:string><json:string>serotonergic neurons</json:string><json:string>glycinergic innervation</json:string><json:string>ennis</json:string><json:string>solitary tract</json:string><json:string>ventral part</json:string><json:string>more caudally</json:string><json:string>injection cases</json:string><json:string>moderate proportion</json:string><json:string>raphe magnus</json:string><json:string>saint marie</json:string><json:string>vector labs</json:string><json:string>large number</json:string><json:string>glycine immunohistochemistry</json:string><json:string>primary antiserum</json:string><json:string>oral part</json:string><json:string>dorsal raphe nuclei</json:string><json:string>spinal motoneurons</json:string><json:string>proximal dendrites</json:string><json:string>superior olivary</json:string><json:string>locus coeruleus neurones</json:string></teeft></keywords><author><json:item><name>Claire Rampon</name><affiliations><json:string>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</json:string></affiliations></json:item><json:item><name>Christelle Peyron</name><affiliations><json:string>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</json:string></affiliations></json:item><json:item><name>Damien Gervasoni</name><affiliations><json:string>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</json:string></affiliations></json:item><json:item><name>David V. Pow</name><affiliations><json:string>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</json:string><json:string>Vision, Touch and Hearing Research Center, University of Queensland, Brisbane, Australia</json:string></affiliations></json:item><json:item><name>Pierre‐Hervé Luppi</name><affiliations><json:string>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</json:string></affiliations></json:item><json:item><name>Patrice Fort</name><affiliations><json:string>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>amino acid</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>inhibitory neurotransmitter</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>monoamine</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>noradrenaline</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>paradoxical sleep</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>serotonin</value></json:item></subject><articleId><json:string>EJN511</json:string></articleId><arkIstex>ark:/67375/WNG-12HPGGN2-2</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>The amino acid glycine is a major inhibitory neurotransmitter in the brainstem and is likely involved in the tonic inhibition of the monoaminergic neurons during all sleep‐waking stages. In order to determine the neurons at the origin of the glycinergic innervation of the two principal monoaminergic nuclei, the locus coeruleus and the dorsal raphe of the rat, we applied a double‐labelling technique, combining retrograde transport of cholera‐toxin B subunit with glycine immunohistochemistry. Using this technique, we found that the locus coeruleus and dorsal raphe nuclei receive a common glycinergic innervation from the ventral and ventrolateral periaqueductal grey, including the adjacent deep mesencephalic reticular nucleus. Small additional glycinergic inputs to these nuclei originated from the lateral paragigantocellular nucleus and the rostral ventromedial medullary reticular formation. The potential role of these glycinergic inputs in the control of the excitability of the monoaminergic neurons of the locus coeruleus and dorsal raphe nuclei is discussed.</abstract><qualityIndicators><score>8.812</score><pdfWordCount>6965</pdfWordCount><pdfCharCount>44787</pdfCharCount><pdfVersion>1.1</pdfVersion><pdfPageCount>9</pdfPageCount><pdfPageSize>595 x 842 pts (A4)</pdfPageSize><refBibsNative>true</refBibsNative><abstractWordCount>151</abstractWordCount><abstractCharCount>1073</abstractCharCount><keywordCount>6</keywordCount></qualityIndicators><title>Origins of the glycinergic inputs to the rat locus coeruleus and dorsal raphe nuclei: a study combining retrograde tracing with glycine immunohistochemistry</title><pmid><json:string>10103098</json:string></pmid><genre><json:string>article</json:string></genre><host><title>European Journal of Neuroscience</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)1460-9568</json:string></doi><issn><json:string>0953-816X</json:string></issn><eissn><json:string>1460-9568</json:string></eissn><publisherId><json:string>EJN</json:string></publisherId><volume>11</volume><issue>3</issue><pages><first>1058</first><last>1066</last><total>9</total></pages><genre><json:string>journal</json:string></genre></host><namedEntities><unitex><date><json:string>1999</json:string></date><geogName></geogName><orgName><json:string>Grass Instruments</json:string><json:string>Jackson ImmunoResearch Laboratories</json:string><json:string>Vector Laboratories</json:string><json:string>List Biological Laboratories</json:string><json:string>Clark Electromedical Instruments</json:string></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName><json:string>David V. Pow</json:string><json:string>H. Luppi</json:string><json:string>Pierre-Herve Luppi</json:string><json:string>Pow</json:string><json:string>Damien Gervasoni</json:string><json:string>In</json:string><json:string>Christelle Peyron</json:string><json:string>K. Srere</json:string><json:string>Dr Hillary</json:string><json:string>Patrice Fort</json:string></persName><placeName><json:string>Burlingame</json:string><json:string>UK</json:string><json:string>West Grove</json:string><json:string>USA</json:string><json:string>Campbell</json:string><json:string>CA</json:string><json:string>France</json:string><json:string>Lyon</json:string><json:string>PA</json:string><json:string>Warwick</json:string></placeName><ref_url></ref_url><ref_bibl><json:string>Trulson & Jacobs, 1979</json:string><json:string>Aston-Jones & Bloom, 1981</json:string><json:string>Saint Marie & Baker, 1990</json:string><json:string>1997a, 1997b</json:string><json:string>Campistron et al., 1986</json:string><json:string>Barbaresi & Manfrini, 1988</json:string><json:string>Siegel (1997a,b)</json:string><json:string>Walberg et al., 1990</json:string><json:string>C. Rampon et al.</json:string><json:string>Aghajanian & VanderMaelen, 1982</json:string><json:string>Fort et al., 1993</json:string><json:string>Darracq et al., 1996</json:string><json:string>Zarbin et al., 1981</json:string><json:string>Hobson, 1990</json:string><json:string>reviewed in Jouvet, 1972</json:string><json:string>McGinty & Harper, 1976</json:string><json:string>Sato et al., 1991</json:string><json:string>Sakai et al., 1981</json:string><json:string>Bird & Kuhar, 1977</json:string><json:string>Ford et al., 1995</json:string><json:string>Van den Pol & Gorcs, 1988</json:string><json:string>Rampon et al., 1996c</json:string><json:string>Gallager & Aghajanian, 1976</json:string><json:string>Fort et al., 1990, 1993</json:string><json:string>Turman & Chandler, 1994</json:string><json:string>Benson & Potashner, 1990</json:string><json:string>Gallager, 1978</json:string><json:string>Barbaresi et al., 1997</json:string><json:string>according to the atlas of Paxinos & Watson, 1997</json:string><json:string>reviewed in Beitz, 1995</json:string><json:string>Ennis & AstonJones, 1988</json:string><json:string>Rampon et al., 1996b</json:string><json:string>Clements et al., 1987</json:string><json:string>Drolet et al., 1992</json:string><json:string>Araki et al., 1988</json:string><json:string>Saint Marie et al., 1991</json:string><json:string>Luppi et al., 1991</json:string><json:string>Williams et al., 1984</json:string><json:string>reviewed in Sakai, 1985</json:string><json:string>Rampon et al., 1996a</json:string><json:string>Rampon et al., 1996a, 1996c</json:string><json:string>Sakai, 1985</json:string><json:string>Yamuy et al., 1993</json:string><json:string>Luppi et al., 1991, 1995</json:string><json:string>Jouvet et al., 1995</json:string><json:string>Wenthold et al., 1987</json:string><json:string>Aston-Jones et al., 1992</json:string><json:string>Luppi et al., 1990</json:string><json:string>Holstege, 1996</json:string><json:string>Sastre et al., 1996</json:string><json:string>Luppi et al., 1995</json:string><json:string>Pieribone et al., 1990</json:string><json:string>Holstege & Bongers, 1991</json:string><json:string>Pow et al., 1995</json:string><json:string>Peyron et al., 1995</json:string><json:string>Pourcho et al., 1992</json:string><json:string>Ennis & Aston-Jones, 1989</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/WNG-12HPGGN2-2</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - neurosciences</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - clinical medicine</json:string><json:string>3 - neurology & neurosurgery</json:string></scienceMetrix><scopus><json:string>1 - Life Sciences</json:string><json:string>2 - Neuroscience</json:string><json:string>3 - General Neuroscience</json:string></scopus><inist><json:string>1 - sciences appliquees, technologies et 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type="main">Origins of the glycinergic inputs to the rat locus coeruleus and dorsal raphe nuclei: a study combining retrograde tracing with glycine immunohistochemistry</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Science Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1999-03"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Origins of the glycinergic inputs to the rat locus coeruleus and dorsal raphe nuclei: a study combining retrograde tracing with glycine immunohistochemistry</title><title level="a" type="short">Glycinergic inputs to the locus coeruleus and dorsal raphe</title><author xml:id="author-0000"><persName><forename type="first">Claire</forename><surname>Rampon</surname></persName><affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France<address><country key="FR"></country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">Christelle</forename><surname>Peyron</surname></persName><affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France<address><country key="FR"></country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">Damien</forename><surname>Gervasoni</surname></persName><affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France<address><country key="FR"></country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">David V.</forename><surname>Pow</surname></persName><affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France<address><country key="FR"></country></address></affiliation><affiliation>Vision, Touch and Hearing Research Center, University of Queensland, Brisbane, Australia<address><country key="AU"></country></address></affiliation></author><author xml:id="author-0004"><persName><forename type="first">Pierre‐Hervé</forename><surname>Luppi</surname></persName><affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France<address><country key="FR"></country></address></affiliation></author><author xml:id="author-0005"><persName><forename type="first">Patrice</forename><surname>Fort</surname></persName><affiliation>Neurobiologie des Etats de Sommeil et d'Eveil, INSERM U480, Lyon, France<address><country key="FR"></country></address></affiliation></author><idno type="istex">1A74E7E0146DD78C5305A1848EB37FA363EC7C7E</idno><idno type="ark">ark:/67375/WNG-12HPGGN2-2</idno><idno type="DOI">10.1046/j.1460-9568.1999.00511.x</idno><idno 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