The neuro-electronic interface: measurements and model predictions
Identifieur interne : 001841 ( Istex/Corpus ); précédent : 001840; suivant : 001842The neuro-electronic interface: measurements and model predictions
Auteurs : M. Grattarola ; M. Bove ; G. Verreschi ; S. Martinoia ; M. TedescoSource :
- Journal of Materials Science: Materials in Medicine [ 0957-4530 ] ; 1996-06-01.
Abstract
Abstract: The functional coupling of populations of chick embryo dorsal root ganglia (DRG) neurons to planar arrays of microelectrodes has been characterized both experimentally and via computer simulatiors. Spontaneous electrical activity recorded with a multichannel automated workstation is compared with simulated activity, whose signal-to-noise ratio has been systematically varied by simulating changes in the strength of the neuron-to-substrate abhesion. The importance of this approach for the design of optimized neuro-electronic prostheses and for the development of new tools for in vitro screening tests is briefly discussed.
Url:
DOI: 10.1007/BF00154550
Links to Exploration step
ISTEX:26EB9EF70025C140E5C86AEE5C81E4EF55D4BACALe document en format XML
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Verreschi</name><affiliation><mods:affiliation>Bioelectronics Laboratory, Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</mods:affiliation></affiliation><affiliation><mods:affiliation>Bioelectronic Technologies Laboratory (c/o Advanced Biotechnology Center), Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</mods:affiliation></affiliation></author><author><name sortKey="Martinoia, S" sort="Martinoia, S" uniqKey="Martinoia S" first="S." last="Martinoia">S. 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Tedesco</name><affiliation><mods:affiliation>Bioelectronics Laboratory, Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</mods:affiliation></affiliation><affiliation><mods:affiliation>Bioelectronic Technologies Laboratory (c/o Advanced Biotechnology Center), Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Materials Science: Materials in Medicine</title><title level="j" type="sub">Official Journal of the European Society for Biomaterials</title><title level="j" type="abbrev">J Mater Sci: Mater Med</title><idno type="ISSN">0957-4530</idno><idno type="eISSN">1573-4838</idno><imprint><publisher>Kluwer Academic Publishers; http://www.chaphall.com.chaphal/journals.html</publisher><pubPlace>Dordrecht</pubPlace><date type="published" when="1996-06-01">1996-06-01</date><biblScope unit="volume">7</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="363">363</biblScope><biblScope unit="page" to="366">366</biblScope></imprint><idno type="ISSN">0957-4530</idno></series><idno type="istex">26EB9EF70025C140E5C86AEE5C81E4EF55D4BACA</idno><idno type="DOI">10.1007/BF00154550</idno><idno type="ArticleID">Art11</idno><idno type="ArticleID">BF00154550</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0957-4530</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: The functional coupling of populations of chick embryo dorsal root ganglia (DRG) neurons to planar arrays of microelectrodes has been characterized both experimentally and via computer simulatiors. Spontaneous electrical activity recorded with a multichannel automated workstation is compared with simulated activity, whose signal-to-noise ratio has been systematically varied by simulating changes in the strength of the neuron-to-substrate abhesion. The importance of this approach for the design of optimized neuro-electronic prostheses and for the development of new tools for in vitro screening tests is briefly discussed.</div></front></TEI><istex><corpusName>springer</corpusName><author><json:item><name>M. Grattarola</name><affiliations><json:string>Bioelectronics Laboratory, Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</json:string><json:string>Bioelectronic Technologies Laboratory (c/o Advanced Biotechnology Center), Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</json:string></affiliations></json:item><json:item><name>M. 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Tedesco</name><affiliations><json:string>Bioelectronics Laboratory, Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</json:string><json:string>Bioelectronic Technologies Laboratory (c/o Advanced Biotechnology Center), Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</json:string></affiliations></json:item></author><articleId><json:string>Art11</json:string><json:string>BF00154550</json:string></articleId><language><json:string>eng</json:string></language><abstract>Abstract: The functional coupling of populations of chick embryo dorsal root ganglia (DRG) neurons to planar arrays of microelectrodes has been characterized both experimentally and via computer simulatiors. Spontaneous electrical activity recorded with a multichannel automated workstation is compared with simulated activity, whose signal-to-noise ratio has been systematically varied by simulating changes in the strength of the neuron-to-substrate abhesion. 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Spontaneous electrical activity recorded with a multichannel automated workstation is compared with simulated activity, whose signal-to-noise ratio has been systematically varied by simulating changes in the strength of the neuron-to-substrate abhesion. The importance of this approach for the design of optimized neuro-electronic prostheses and for the development of new tools for in vitro screening tests is briefly discussed.</p></abstract><textClass><keywords scheme="Journal Subject"><list><head>Chemistry</head><item><term>Biotechnology</term></item><item><term>Polymer Sciences</term></item><item><term>Characterization and Evaluation Materials</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1996-06-01">Published</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2016-3-2">References added</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/26EB9EF70025C140E5C86AEE5C81E4EF55D4BACA/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Springer, Publisher found" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" 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DisplayOrder="Western"><GivenName>M.</GivenName><FamilyName>Tedesco</FamilyName></AuthorName></Author><Affiliation ID="Aff1"><OrgDivision>Bioelectronics Laboratory</OrgDivision><OrgName>Department of Biophysical and Electronic Engineering (D.I.B.E.)</OrgName><OrgAddress><Street>Via Opera Pia 11a</Street><Postcode>16145</Postcode><City>Genova</City><Country>Italy</Country></OrgAddress></Affiliation><Affiliation ID="Aff2"><OrgDivision>Bioelectronic Technologies Laboratory (c/o Advanced Biotechnology Center)</OrgDivision><OrgName>Department of Biophysical and Electronic Engineering (D.I.B.E.)</OrgName><OrgAddress><Street>Via Opera Pia 11a</Street><Postcode>16145</Postcode><City>Genova</City><Country>Italy</Country></OrgAddress></Affiliation></AuthorGroup><Abstract ID="Abs1" Language="En"><Heading>Abstract</Heading><Para>The functional coupling of populations of chick embryo dorsal root ganglia (DRG) neurons to planar arrays of microelectrodes has been characterized both experimentally and via computer simulatiors. Spontaneous electrical activity recorded with a multichannel automated workstation is compared with simulated activity, whose signal-to-noise ratio has been systematically varied by simulating changes in the strength of the neuron-to-substrate abhesion. The importance of this approach for the design of optimized neuro-electronic prostheses and for the development of new tools for <Emphasis Type="Italic">in vitro</Emphasis> screening tests is briefly discussed.</Para></Abstract><ArticleNote Type="Misc"><SimplePara>This paper was accepted for publication after the 1995 Conference of the European Society of Biomaterials, Oporto, Portugal, 10–13 September.</SimplePara></ArticleNote></ArticleHeader><NoBody></NoBody></Article></Issue></Volume></Journal></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>The neuro-electronic interface: measurements and model predictions</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>The neuro-electronic interface: measurements and model predictions</title></titleInfo><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Grattarola</namePart><affiliation>Bioelectronics Laboratory, Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</affiliation><affiliation>Bioelectronic Technologies Laboratory (c/o Advanced Biotechnology Center), Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Bove</namePart><affiliation>Bioelectronics Laboratory, Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</affiliation><affiliation>Bioelectronic Technologies Laboratory (c/o Advanced Biotechnology Center), Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G.</namePart><namePart type="family">Verreschi</namePart><affiliation>Bioelectronics Laboratory, Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</affiliation><affiliation>Bioelectronic Technologies Laboratory (c/o Advanced Biotechnology Center), Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S.</namePart><namePart type="family">Martinoia</namePart><affiliation>Bioelectronics Laboratory, Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</affiliation><affiliation>Bioelectronic Technologies Laboratory (c/o Advanced Biotechnology Center), Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Tedesco</namePart><affiliation>Bioelectronics Laboratory, Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</affiliation><affiliation>Bioelectronic Technologies Laboratory (c/o Advanced Biotechnology Center), Department of Biophysical and Electronic Engineering (D.I.B.E.), Via Opera Pia 11a, 16145, Genova, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="OriginalPaper"></genre><originInfo><publisher>Kluwer Academic Publishers; http://www.chaphall.com.chaphal/journals.html</publisher><place><placeTerm type="text">Dordrecht</placeTerm></place><dateIssued encoding="w3cdtf">1996-06-01</dateIssued><copyrightDate encoding="w3cdtf">1996</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Abstract: The functional coupling of populations of chick embryo dorsal root ganglia (DRG) neurons to planar arrays of microelectrodes has been characterized both experimentally and via computer simulatiors. Spontaneous electrical activity recorded with a multichannel automated workstation is compared with simulated activity, whose signal-to-noise ratio has been systematically varied by simulating changes in the strength of the neuron-to-substrate abhesion. The importance of this approach for the design of optimized neuro-electronic prostheses and for the development of new tools for in vitro screening tests is briefly discussed.</abstract><note>This paper was accepted for publication after the 1995 Conference of the European Society of Biomaterials, Oporto, Portugal, 10–13 September.</note><relatedItem type="host"><titleInfo><title>Journal of Materials Science: Materials in Medicine</title><subTitle>Official Journal of the European Society for Biomaterials</subTitle></titleInfo><titleInfo type="abbreviated"><title>J Mater Sci: Mater Med</title></titleInfo><genre type="Journal" displayLabel="Archive Journal"></genre><originInfo><dateIssued encoding="w3cdtf">1996-06-01</dateIssued><copyrightDate encoding="w3cdtf">1996</copyrightDate></originInfo><subject><genre>Chemistry</genre><topic>Biotechnology</topic><topic>Polymer Sciences</topic><topic>Characterization and Evaluation Materials</topic></subject><identifier type="ISSN">0957-4530</identifier><identifier type="eISSN">1573-4838</identifier><identifier type="JournalID">10856</identifier><identifier type="IssueArticleCount">15</identifier><identifier type="VolumeIssueCount">12</identifier><part><date>1996</date><detail type="volume"><number>7</number><caption>vol.</caption></detail><detail type="issue"><number>6</number><caption>no.</caption></detail><extent unit="pages"><start>363</start><end>366</end></extent></part><recordInfo><recordOrigin>Chapman & Hall, 1996</recordOrigin></recordInfo></relatedItem><identifier type="istex">26EB9EF70025C140E5C86AEE5C81E4EF55D4BACA</identifier><identifier type="DOI">10.1007/BF00154550</identifier><identifier type="ArticleID">Art11</identifier><identifier type="ArticleID">BF00154550</identifier><accessCondition type="use and reproduction" contentType="copyright">Chapman & Hall</accessCondition><recordInfo><recordContentSource>SPRINGER</recordContentSource><recordOrigin>Chapman & Hall, 1996</recordOrigin></recordInfo></mods></metadata><enrichments><istex:refBibTEI uri="https://api.istex.fr/document/26EB9EF70025C140E5C86AEE5C81E4EF55D4BACA/enrichments/refBib"><teiHeader></teiHeader><text><front></front><body></body><back><listBibl><biblStruct xml:id="b0"><analytic><title></title><author><persName><forename type="first">G</forename><forename type="middle">T A</forename><surname>Kovacs</surname></persName></author><author><persName><forename type="first">C</forename><forename type="middle">W</forename><surname>Storment</surname></persName></author><author><persName><forename type="first">M</forename><surname>Halks-Mil-Ler</surname></persName></author><author><persName><forename type="first">C</forename><forename type="middle">R</forename><surname>Belczynsky</surname></persName></author><author><persName><forename type="first">C</forename><forename type="middle">C</forename><surname>Della</surname></persName></author><author><persName><forename type="first">E</forename><forename type="middle">R</forename><surname>Santina</surname></persName></author><author><persName><forename type="first">N</forename><forename type="middle">I</forename><surname>Lewis</surname></persName></author><author><persName><surname>Maluf</surname></persName></author></analytic><monogr><title level="j">IEEE Trans. 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