Is it possible to diagnose TB in ancient bone using microscopy?
Identifieur interne : 000105 ( PubMed/Corpus ); précédent : 000104; suivant : 000106Is it possible to diagnose TB in ancient bone using microscopy?
Auteurs : Michael Schultz ; Tyede H. Schmidt-SchultzSource :
- Tuberculosis (Edinburgh, Scotland) [ 1873-281X ] ; 2015.
English descriptors
- KwdEn :
- MESH :
- history : Tuberculosis, Osteoarticular.
- methods : Microscopy, Paleopathology.
- pathology : Tuberculosis, Miliary, Tuberculosis, Osteoarticular.
- Adult, Diagnosis, Differential, Female, History, Medieval, Humans, Male, Young Adult.
Abstract
In paleopathology, light microscopy, particularly the use of polarized transmission light, is highly valued for the establishment of reliable diagnoses. Recently, there has been a considerable widening of our experience in the diagnosis of pathological conditions at the micro-level using thin-ground sections prepared from archaeological bone. Thus, the question has arisen as to whether it might also be possible to diagnose tuberculous disease in archaeological bone using microscopy. As a rule, the reliability of a diagnosis established on the basis of thin-ground sections depends on the state of preservation of the selected sample (e.g., pseudopathology). However, sometimes, although the preservation is fairly good, a diagnosis cannot easily be established because the characteristic criteria (e.g., mosaic structure, in Paget's disease) are not clearly observable or seem to be ambiguous. In this case, we assumed that the pathophysiological nature of the morphological structures should be analyzed (e.g., the speed of growth of pathological newly built bone formations) which might help to differentiate between nonspecific (e.g., hematogenous osteomyelitis) and specific inflammatory bone diseases (e.g., tuberculous bone disease). To verify this assumption, samples were taken from recent bone collection materials with known disease diagnoses and from archaeological specimens which show lesions suspicious of bone tuberculosis (e.g., bone tuberculosis, tuberculous meningitis).
DOI: 10.1016/j.tube.2015.02.035
PubMed: 25744278
Links to Exploration step
pubmed:25744278Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Is it possible to diagnose TB in ancient bone using microscopy?</title>
<author><name sortKey="Schultz, Michael" sort="Schultz, Michael" uniqKey="Schultz M" first="Michael" last="Schultz">Michael Schultz</name>
<affiliation><nlm:affiliation>Department of Anatomy, University Medical School Göttingen, Kreuzbergring 36, D-37075 Göttingen, Germany. Electronic address: mschult1@gwdg.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Schmidt Schultz, Tyede H" sort="Schmidt Schultz, Tyede H" uniqKey="Schmidt Schultz T" first="Tyede H" last="Schmidt-Schultz">Tyede H. Schmidt-Schultz</name>
<affiliation><nlm:affiliation>Department of Anatomy, University Medical School Göttingen, Kreuzbergring 36, D-37075 Göttingen, Germany. Electronic address: tschmidt-schultz@web.de.</nlm:affiliation>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2015">2015</date>
<idno type="RBID">pubmed:25744278</idno>
<idno type="pmid">25744278</idno>
<idno type="doi">10.1016/j.tube.2015.02.035</idno>
<idno type="wicri:Area/PubMed/Corpus">000105</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000105</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Is it possible to diagnose TB in ancient bone using microscopy?</title>
<author><name sortKey="Schultz, Michael" sort="Schultz, Michael" uniqKey="Schultz M" first="Michael" last="Schultz">Michael Schultz</name>
<affiliation><nlm:affiliation>Department of Anatomy, University Medical School Göttingen, Kreuzbergring 36, D-37075 Göttingen, Germany. Electronic address: mschult1@gwdg.de.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Schmidt Schultz, Tyede H" sort="Schmidt Schultz, Tyede H" uniqKey="Schmidt Schultz T" first="Tyede H" last="Schmidt-Schultz">Tyede H. Schmidt-Schultz</name>
<affiliation><nlm:affiliation>Department of Anatomy, University Medical School Göttingen, Kreuzbergring 36, D-37075 Göttingen, Germany. Electronic address: tschmidt-schultz@web.de.</nlm:affiliation>
</affiliation>
</author>
</analytic>
<series><title level="j">Tuberculosis (Edinburgh, Scotland)</title>
<idno type="eISSN">1873-281X</idno>
<imprint><date when="2015" type="published">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Diagnosis, Differential</term>
<term>Female</term>
<term>History, Medieval</term>
<term>Humans</term>
<term>Male</term>
<term>Microscopy (methods)</term>
<term>Paleopathology (methods)</term>
<term>Tuberculosis, Miliary (pathology)</term>
<term>Tuberculosis, Osteoarticular (history)</term>
<term>Tuberculosis, Osteoarticular (pathology)</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" qualifier="history" xml:lang="en"><term>Tuberculosis, Osteoarticular</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Microscopy</term>
<term>Paleopathology</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Tuberculosis, Miliary</term>
<term>Tuberculosis, Osteoarticular</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Diagnosis, Differential</term>
<term>Female</term>
<term>History, Medieval</term>
<term>Humans</term>
<term>Male</term>
<term>Young Adult</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">In paleopathology, light microscopy, particularly the use of polarized transmission light, is highly valued for the establishment of reliable diagnoses. Recently, there has been a considerable widening of our experience in the diagnosis of pathological conditions at the micro-level using thin-ground sections prepared from archaeological bone. Thus, the question has arisen as to whether it might also be possible to diagnose tuberculous disease in archaeological bone using microscopy. As a rule, the reliability of a diagnosis established on the basis of thin-ground sections depends on the state of preservation of the selected sample (e.g., pseudopathology). However, sometimes, although the preservation is fairly good, a diagnosis cannot easily be established because the characteristic criteria (e.g., mosaic structure, in Paget's disease) are not clearly observable or seem to be ambiguous. In this case, we assumed that the pathophysiological nature of the morphological structures should be analyzed (e.g., the speed of growth of pathological newly built bone formations) which might help to differentiate between nonspecific (e.g., hematogenous osteomyelitis) and specific inflammatory bone diseases (e.g., tuberculous bone disease). To verify this assumption, samples were taken from recent bone collection materials with known disease diagnoses and from archaeological specimens which show lesions suspicious of bone tuberculosis (e.g., bone tuberculosis, tuberculous meningitis).</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25744278</PMID>
<DateCreated><Year>2015</Year>
<Month>06</Month>
<Day>23</Day>
</DateCreated>
<DateCompleted><Year>2016</Year>
<Month>03</Month>
<Day>25</Day>
</DateCompleted>
<DateRevised><Year>2015</Year>
<Month>06</Month>
<Day>23</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-281X</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>95 Suppl 1</Volume>
<PubDate><Year>2015</Year>
<Month>Jun</Month>
</PubDate>
</JournalIssue>
<Title>Tuberculosis (Edinburgh, Scotland)</Title>
<ISOAbbreviation>Tuberculosis (Edinb)</ISOAbbreviation>
</Journal>
<ArticleTitle>Is it possible to diagnose TB in ancient bone using microscopy?</ArticleTitle>
<Pagination><MedlinePgn>S80-6</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.tube.2015.02.035</ELocationID>
<ELocationID EIdType="pii" ValidYN="Y">S1472-9792(15)00036-0</ELocationID>
<Abstract><AbstractText>In paleopathology, light microscopy, particularly the use of polarized transmission light, is highly valued for the establishment of reliable diagnoses. Recently, there has been a considerable widening of our experience in the diagnosis of pathological conditions at the micro-level using thin-ground sections prepared from archaeological bone. Thus, the question has arisen as to whether it might also be possible to diagnose tuberculous disease in archaeological bone using microscopy. As a rule, the reliability of a diagnosis established on the basis of thin-ground sections depends on the state of preservation of the selected sample (e.g., pseudopathology). However, sometimes, although the preservation is fairly good, a diagnosis cannot easily be established because the characteristic criteria (e.g., mosaic structure, in Paget's disease) are not clearly observable or seem to be ambiguous. In this case, we assumed that the pathophysiological nature of the morphological structures should be analyzed (e.g., the speed of growth of pathological newly built bone formations) which might help to differentiate between nonspecific (e.g., hematogenous osteomyelitis) and specific inflammatory bone diseases (e.g., tuberculous bone disease). To verify this assumption, samples were taken from recent bone collection materials with known disease diagnoses and from archaeological specimens which show lesions suspicious of bone tuberculosis (e.g., bone tuberculosis, tuberculous meningitis).</AbstractText>
<CopyrightInformation>Copyright © 2015 Elsevier Ltd. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Schultz</LastName>
<ForeName>Michael</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Anatomy, University Medical School Göttingen, Kreuzbergring 36, D-37075 Göttingen, Germany. Electronic address: mschult1@gwdg.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Schmidt-Schultz</LastName>
<ForeName>Tyede H</ForeName>
<Initials>TH</Initials>
<AffiliationInfo><Affiliation>Department of Anatomy, University Medical School Göttingen, Kreuzbergring 36, D-37075 Göttingen, Germany. Electronic address: tschmidt-schultz@web.de.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016456">Historical Article</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2015</Year>
<Month>02</Month>
<Day>13</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Scotland</Country>
<MedlineTA>Tuberculosis (Edinb)</MedlineTA>
<NlmUniqueID>100971555</NlmUniqueID>
<ISSNLinking>1472-9792</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003937" MajorTopicYN="N">Diagnosis, Differential</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D049691" MajorTopicYN="N">History, Medieval</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008853" MajorTopicYN="N">Microscopy</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010164" MajorTopicYN="N">Paleopathology</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014391" MajorTopicYN="N">Tuberculosis, Miliary</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014394" MajorTopicYN="N">Tuberculosis, Osteoarticular</DescriptorName>
<QualifierName UI="Q000266" MajorTopicYN="N">history</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Light microscopy</Keyword>
<Keyword MajorTopicYN="N">Nonspecific inflammatory bone disease</Keyword>
<Keyword MajorTopicYN="N">Pseudopathology</Keyword>
<Keyword MajorTopicYN="N">Tuberculosis</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2015</Year>
<Month>3</Month>
<Day>7</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2015</Year>
<Month>3</Month>
<Day>7</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2016</Year>
<Month>3</Month>
<Day>26</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">25744278</ArticleId>
<ArticleId IdType="pii">S1472-9792(15)00036-0</ArticleId>
<ArticleId IdType="doi">10.1016/j.tube.2015.02.035</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Archeologie/explor/PaleopathV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000105 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000105 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Archeologie |area= PaleopathV1 |flux= PubMed |étape= Corpus |type= RBID |clé= pubmed:25744278 |texte= Is it possible to diagnose TB in ancient bone using microscopy? }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:25744278" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \ | NlmPubMed2Wicri -a PaleopathV1
This area was generated with Dilib version V0.6.27. |