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Quantitative sodium MR imaging of native versus transplanted kidneys using a dual-tuned proton/sodium (1H/ 23Na) coil: initial experience.

Identifieur interne : 002997 ( PubMed/Corpus ); précédent : 002996; suivant : 002998

Quantitative sodium MR imaging of native versus transplanted kidneys using a dual-tuned proton/sodium (1H/ 23Na) coil: initial experience.

Auteurs : Chan Hong Moon ; Alessandro Furlan ; Jung-Hwan Kim ; Tiejun Zhao ; Ron Shapiro ; Kyongtae Ty Bae

Source :

RBID : pubmed:24668008

English descriptors

Abstract

To compare sodium ((23)Na) characteristics between native and transplanted kidneys using dual-tuned proton ((1)H)/sodium MRI.

DOI: 10.1007/s00330-014-3138-5
PubMed: 24668008

Links to Exploration step

pubmed:24668008

Le document en format XML

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<title xml:lang="en">Quantitative sodium MR imaging of native versus transplanted kidneys using a dual-tuned proton/sodium (1H/ 23Na) coil: initial experience.</title>
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<name sortKey="Moon, Chan Hong" sort="Moon, Chan Hong" uniqKey="Moon C" first="Chan Hong" last="Moon">Chan Hong Moon</name>
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<nlm:affiliation>Department of Radiology, University of Pittsburgh, 200 Lothrop Street, Presby South tower Suite 3950, Pittsburgh, PA, 15213, USA.</nlm:affiliation>
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<name sortKey="Furlan, Alessandro" sort="Furlan, Alessandro" uniqKey="Furlan A" first="Alessandro" last="Furlan">Alessandro Furlan</name>
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<term>Graft Rejection (metabolism)</term>
<term>Graft Rejection (pathology)</term>
<term>Humans</term>
<term>Kidney Cortex (metabolism)</term>
<term>Kidney Cortex (pathology)</term>
<term>Kidney Medulla (metabolism)</term>
<term>Kidney Medulla (pathology)</term>
<term>Kidney Transplantation</term>
<term>Magnetic Resonance Imaging (instrumentation)</term>
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<term>Protons</term>
<term>Radio Waves</term>
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<term>Signal-To-Noise Ratio</term>
<term>Sodium (metabolism)</term>
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<term>Sodium</term>
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<term>Protons</term>
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<term>Magnetic Resonance Imaging</term>
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<term>Graft Rejection</term>
<term>Kidney Cortex</term>
<term>Kidney Medulla</term>
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<term>Magnetic Resonance Imaging</term>
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<div type="abstract" xml:lang="en">To compare sodium ((23)Na) characteristics between native and transplanted kidneys using dual-tuned proton ((1)H)/sodium MRI.</div>
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<Month>05</Month>
<Day>16</Day>
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<DateCompleted>
<Year>2014</Year>
<Month>11</Month>
<Day>10</Day>
</DateCompleted>
<DateRevised>
<Year>2017</Year>
<Month>09</Month>
<Day>29</Day>
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<ISSN IssnType="Electronic">1432-1084</ISSN>
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<Volume>24</Volume>
<Issue>6</Issue>
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<Year>2014</Year>
<Month>Jun</Month>
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<Title>European radiology</Title>
<ISOAbbreviation>Eur Radiol</ISOAbbreviation>
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<ArticleTitle>Quantitative sodium MR imaging of native versus transplanted kidneys using a dual-tuned proton/sodium (1H/ 23Na) coil: initial experience.</ArticleTitle>
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<AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">To compare sodium ((23)Na) characteristics between native and transplanted kidneys using dual-tuned proton ((1)H)/sodium MRI.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Six healthy volunteers and six renal transplant patients (3 normal function, 3 acute allograft rejection) were included. Proton/sodium MRI was obtained at 3 T using a dual-tuned coil. Signal to noise ratio (SNR), sodium concentration ([(23)Na]) and cortico-medullary sodium gradient (CMSG) were measured. Reproducibility of [(23)Na] measurement was also tested. SNR, [(23)Na] and CMSG of the native and transplanted kidneys were compared.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Proton and sodium images of kidneys were successfully acquired. SNR and [(23)Na] measurements of the native kidneys were reproducible at two different sessions. [(23)Na] and CMSG of the transplanted kidneys was significantly lower than those of the native kidneys: 153.5 ± 11.9 vs. 192.9 ± 9.6 mM (P = 0.002) and 8.9 ± 1.5 vs. 10.5 ± 0.9 mM/mm (P = 0.041), respectively. [(23)Na] and CMSG of the transplanted kidneys with normal function vs. acute rejection were not statistically different.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Sodium quantification of kidneys was reliably performed using proton/sodium MRI. [(23)Na] and CMSG of the transplanted kidneys were lower than those of the native kidneys, but without a statistically significant difference between patients with or without renal allograft rejection.</AbstractText>
<AbstractText Label="KEY POINTS" NlmCategory="CONCLUSIONS">Dual-tuned proton/sodium RF coil enables co-registered proton and sodium MRI. Structural and sodium biochemical property can be acquired by dual-tuned proton/sodium MRI. Sodium and sodium gradient of kidneys can be measured by dual-tuned MRI. Sodium concentration was lower in transplanted kidneys than in native kidneys. Sodium gradient of transplanted kidneys was lower than for native kidneys.</AbstractText>
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<LastName>Moon</LastName>
<ForeName>Chan Hong</ForeName>
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<RefSource>Radiology. 2005 Sep;236(3):911-9</RefSource>
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