Serveur d'exploration sur Pittsburgh

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Sex differences in response to reduced nicotine content cigarettes.

Identifieur interne : 002527 ( PubMed/Corpus ); précédent : 002526; suivant : 002528

Sex differences in response to reduced nicotine content cigarettes.

Auteurs : Rachel Isaksson Vogel ; Louise A. Hertsgaard ; Sarah S. Dermody ; Xianghua Luo ; Lor Moua ; Sharon Allen ; Mustafa Al'Absi ; Dorothy K. Hatsukami

Source :

RBID : pubmed:24746485

English descriptors

Abstract

When switching from usual brand cigarettes, very low nicotine content (VLNC) cigarettes lead to a reduction in the number of cigarettes smoked, toxicant exposure, withdrawal symptoms and dependence. One area that has been relatively unexplored is what factors might moderate the effects of VLNC cigarettes. This exploratory analysis focuses on sex differences in responses to VLNC cigarettes and nicotine replacement therapy.

DOI: 10.1016/j.addbeh.2014.03.021
PubMed: 24746485

Links to Exploration step

pubmed:24746485

Le document en format XML

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<div type="abstract" xml:lang="en">When switching from usual brand cigarettes, very low nicotine content (VLNC) cigarettes lead to a reduction in the number of cigarettes smoked, toxicant exposure, withdrawal symptoms and dependence. One area that has been relatively unexplored is what factors might moderate the effects of VLNC cigarettes. This exploratory analysis focuses on sex differences in responses to VLNC cigarettes and nicotine replacement therapy.</div>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">When switching from usual brand cigarettes, very low nicotine content (VLNC) cigarettes lead to a reduction in the number of cigarettes smoked, toxicant exposure, withdrawal symptoms and dependence. One area that has been relatively unexplored is what factors might moderate the effects of VLNC cigarettes. This exploratory analysis focuses on sex differences in responses to VLNC cigarettes and nicotine replacement therapy.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">An exploratory secondary analysis of a randomized trial of 235 participants (58% female, mean age 47 years) comparing a) 0.05-0.09 mg nicotine yield cigarettes; b) 21 mg nicotine patch and 3) 0.05-0.09 nicotine yield cigarettes with 21 mg nicotine patch was conducted. We focused on sex differences in product use, and impact of products on withdrawal response from usual brand cigarettes and abstinence by randomized group.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The combination of VLNC cigarettes and nicotine patch was more effective in reducing use of VLNC cigarettes and withdrawal symptoms among males than females, whereas females were equally responsive to VLNC cigarettes with and without the nicotine patch. Females were more likely to quit smoking than males when assigned to either of the conditions that incorporated the VLNC cigarettes; however, males were more likely to quit smoking in the nicotine patch alone condition than females.</AbstractText>
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