Incidental atypical proliferative lesions in reduction mammoplasty specimens in patients with a history of breast cancer.
Identifieur interne : 002749 ( PubMed/Checkpoint ); précédent : 002748; suivant : 002750Incidental atypical proliferative lesions in reduction mammoplasty specimens in patients with a history of breast cancer.
Auteurs : Zaibo Li [États-Unis] ; Oluwole Fadare ; Omar Hameed ; Chengquan Zhao ; Mohamed Mokhtar DesoukiSource :
- Human pathology [ 1532-8392 ] ; 2014.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Carcinome canalaire du sein (épidémiologie), Carcinome intracanalaire non infiltrant (épidémiologie), Carcinome lobulaire (épidémiologie), Femelle, Humains, Mammoplastie, Prolifération cellulaire, Prévalence, Résultats fortuits, Sujet âgé, Tumeurs du sein (anatomopathologie), Épithélioma in situ (épidémiologie), États précancéreux (épidémiologie), Études rétrospectives.
- MESH :
- anatomopathologie : Tumeurs du sein.
- épidémiologie : Carcinome canalaire du sein, Carcinome intracanalaire non infiltrant, Carcinome lobulaire, Épithélioma in situ, États précancéreux.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Mammoplastie, Prolifération cellulaire, Prévalence, Résultats fortuits, Sujet âgé, Études rétrospectives.
English descriptors
- KwdEn :
- Adult, Aged, Breast Neoplasms (pathology), Carcinoma in Situ (epidemiology), Carcinoma, Ductal, Breast (epidemiology), Carcinoma, Intraductal, Noninfiltrating (epidemiology), Carcinoma, Lobular (epidemiology), Cell Proliferation, Female, Humans, Incidental Findings, Mammaplasty, Middle Aged, Precancerous Conditions (epidemiology), Prevalence, Retrospective Studies.
- MESH :
- epidemiology : Carcinoma in Situ, Carcinoma, Ductal, Breast, Carcinoma, Intraductal, Noninfiltrating, Carcinoma, Lobular, Precancerous Conditions.
- pathology : Breast Neoplasms.
- Adult, Aged, Cell Proliferation, Female, Humans, Incidental Findings, Mammaplasty, Middle Aged, Prevalence, Retrospective Studies.
Abstract
We recently reported the prevalence of atypical proliferative lesions (APL) in reduction mammoplasty specimens from patients that were treated mainly for macromastia with no known history of breast cancer. The current study is to investigate the prevalence of APLs in breast reduction specimens from patients with a history of breast cancer and compare it to that from patients without a history of breast cancer. A retrospective chart review of pathology records on patients that underwent reduction mammoplasty from 2006 to 2012 generated 179 cases. Laterality, specimen weight, number of blocks submitted and presence of APL were recorded and analyzed. We defined APL as invasive carcinoma, ductal (DCIS) or lobular carcinoma in situ, atypical ductal or lobular hyperplasia (ADH or ALH), and flat epithelial atypia (FEA). The presence of papillomas, radial scars and fibroadenomas were also recorded. At least 1 APL was identified in 23 (12.8%) of 179 specimens including invasive lobular carcinoma (n = 3), DCIS (n = 1), ADH/FEA (n = 9) and lobular carcinoma in situ/ALH (n = 10). The most common APL in this cohort was lobular neoplasia (5.6%) followed by ADH and FEA (5.0%). Invasive carcinoma and DCIS was identified in 2.3% of this cohort. In conclusion, the frequency of detection of APLs in patients with history of breast cancer is significantly higher than that in patients without history of breast cancer (12.8% versus 4.3%). Our data assessed the prevalence of APLs in this setting and, therefore, provide new information on decision-making for contralateral breast reduction in patients with history of breast cancer.
DOI: 10.1016/j.humpath.2013.08.010
PubMed: 24182561
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:24182561Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Incidental atypical proliferative lesions in reduction mammoplasty specimens in patients with a history of breast cancer.</title><author><name sortKey="Li, Zaibo" sort="Li, Zaibo" uniqKey="Li Z" first="Zaibo" last="Li">Zaibo Li</name><affiliation wicri:level="2"><nlm:affiliation>Department of Pathology, Magee-Womens Hospital of the UPMC, Pittsburgh, PA 15213, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, Magee-Womens Hospital of the UPMC, Pittsburgh, PA 15213</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Fadare, Oluwole" sort="Fadare, Oluwole" uniqKey="Fadare O" first="Oluwole" last="Fadare">Oluwole Fadare</name></author><author><name sortKey="Hameed, Omar" sort="Hameed, Omar" uniqKey="Hameed O" first="Omar" last="Hameed">Omar Hameed</name></author><author><name sortKey="Zhao, Chengquan" sort="Zhao, Chengquan" uniqKey="Zhao C" first="Chengquan" last="Zhao">Chengquan Zhao</name></author><author><name sortKey="Desouki, Mohamed Mokhtar" sort="Desouki, Mohamed Mokhtar" uniqKey="Desouki M" first="Mohamed Mokhtar" last="Desouki">Mohamed Mokhtar Desouki</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:24182561</idno><idno type="pmid">24182561</idno><idno type="doi">10.1016/j.humpath.2013.08.010</idno><idno type="wicri:Area/PubMed/Corpus">004482</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">004482</idno><idno type="wicri:Area/PubMed/Curation">004430</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">004430</idno><idno type="wicri:Area/PubMed/Checkpoint">004430</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">004430</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Incidental atypical proliferative lesions in reduction mammoplasty specimens in patients with a history of breast cancer.</title><author><name sortKey="Li, Zaibo" sort="Li, Zaibo" uniqKey="Li Z" first="Zaibo" last="Li">Zaibo Li</name><affiliation wicri:level="2"><nlm:affiliation>Department of Pathology, Magee-Womens Hospital of the UPMC, Pittsburgh, PA 15213, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, Magee-Womens Hospital of the UPMC, Pittsburgh, PA 15213</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Fadare, Oluwole" sort="Fadare, Oluwole" uniqKey="Fadare O" first="Oluwole" last="Fadare">Oluwole Fadare</name></author><author><name sortKey="Hameed, Omar" sort="Hameed, Omar" uniqKey="Hameed O" first="Omar" last="Hameed">Omar Hameed</name></author><author><name sortKey="Zhao, Chengquan" sort="Zhao, Chengquan" uniqKey="Zhao C" first="Chengquan" last="Zhao">Chengquan Zhao</name></author><author><name sortKey="Desouki, Mohamed Mokhtar" sort="Desouki, Mohamed Mokhtar" uniqKey="Desouki M" first="Mohamed Mokhtar" last="Desouki">Mohamed Mokhtar Desouki</name></author></analytic><series><title level="j">Human pathology</title><idno type="eISSN">1532-8392</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Breast Neoplasms (pathology)</term><term>Carcinoma in Situ (epidemiology)</term><term>Carcinoma, Ductal, Breast (epidemiology)</term><term>Carcinoma, Intraductal, Noninfiltrating (epidemiology)</term><term>Carcinoma, Lobular (epidemiology)</term><term>Cell Proliferation</term><term>Female</term><term>Humans</term><term>Incidental Findings</term><term>Mammaplasty</term><term>Middle Aged</term><term>Precancerous Conditions (epidemiology)</term><term>Prevalence</term><term>Retrospective Studies</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Carcinome canalaire du sein (épidémiologie)</term><term>Carcinome intracanalaire non infiltrant (épidémiologie)</term><term>Carcinome lobulaire (épidémiologie)</term><term>Femelle</term><term>Humains</term><term>Mammoplastie</term><term>Prolifération cellulaire</term><term>Prévalence</term><term>Résultats fortuits</term><term>Sujet âgé</term><term>Tumeurs du sein (anatomopathologie)</term><term>Épithélioma in situ (épidémiologie)</term><term>États précancéreux (épidémiologie)</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Tumeurs du sein</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Carcinoma in Situ</term><term>Carcinoma, Ductal, Breast</term><term>Carcinoma, Intraductal, Noninfiltrating</term><term>Carcinoma, Lobular</term><term>Precancerous Conditions</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Breast Neoplasms</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Carcinome canalaire du sein</term><term>Carcinome intracanalaire non infiltrant</term><term>Carcinome lobulaire</term><term>Épithélioma in situ</term><term>États précancéreux</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Cell Proliferation</term><term>Female</term><term>Humans</term><term>Incidental Findings</term><term>Mammaplasty</term><term>Middle Aged</term><term>Prevalence</term><term>Retrospective Studies</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Mammoplastie</term><term>Prolifération cellulaire</term><term>Prévalence</term><term>Résultats fortuits</term><term>Sujet âgé</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We recently reported the prevalence of atypical proliferative lesions (APL) in reduction mammoplasty specimens from patients that were treated mainly for macromastia with no known history of breast cancer. The current study is to investigate the prevalence of APLs in breast reduction specimens from patients with a history of breast cancer and compare it to that from patients without a history of breast cancer. A retrospective chart review of pathology records on patients that underwent reduction mammoplasty from 2006 to 2012 generated 179 cases. Laterality, specimen weight, number of blocks submitted and presence of APL were recorded and analyzed. We defined APL as invasive carcinoma, ductal (DCIS) or lobular carcinoma in situ, atypical ductal or lobular hyperplasia (ADH or ALH), and flat epithelial atypia (FEA). The presence of papillomas, radial scars and fibroadenomas were also recorded. At least 1 APL was identified in 23 (12.8%) of 179 specimens including invasive lobular carcinoma (n = 3), DCIS (n = 1), ADH/FEA (n = 9) and lobular carcinoma in situ/ALH (n = 10). The most common APL in this cohort was lobular neoplasia (5.6%) followed by ADH and FEA (5.0%). Invasive carcinoma and DCIS was identified in 2.3% of this cohort. In conclusion, the frequency of detection of APLs in patients with history of breast cancer is significantly higher than that in patients without history of breast cancer (12.8% versus 4.3%). Our data assessed the prevalence of APLs in this setting and, therefore, provide new information on decision-making for contralateral breast reduction in patients with history of breast cancer.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24182561</PMID><DateCreated><Year>2013</Year><Month>12</Month><Day>10</Day></DateCreated><DateCompleted><Year>2014</Year><Month>02</Month><Day>04</Day></DateCompleted><DateRevised><Year>2013</Year><Month>12</Month><Day>10</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1532-8392</ISSN><JournalIssue CitedMedium="Internet"><Volume>45</Volume><Issue>1</Issue><PubDate><Year>2014</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Human pathology</Title><ISOAbbreviation>Hum. Pathol.</ISOAbbreviation></Journal><ArticleTitle>Incidental atypical proliferative lesions in reduction mammoplasty specimens in patients with a history of breast cancer.</ArticleTitle><Pagination><MedlinePgn>104-9</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.humpath.2013.08.010</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0046-8177(13)00350-X</ELocationID><Abstract><AbstractText>We recently reported the prevalence of atypical proliferative lesions (APL) in reduction mammoplasty specimens from patients that were treated mainly for macromastia with no known history of breast cancer. The current study is to investigate the prevalence of APLs in breast reduction specimens from patients with a history of breast cancer and compare it to that from patients without a history of breast cancer. A retrospective chart review of pathology records on patients that underwent reduction mammoplasty from 2006 to 2012 generated 179 cases. Laterality, specimen weight, number of blocks submitted and presence of APL were recorded and analyzed. We defined APL as invasive carcinoma, ductal (DCIS) or lobular carcinoma in situ, atypical ductal or lobular hyperplasia (ADH or ALH), and flat epithelial atypia (FEA). The presence of papillomas, radial scars and fibroadenomas were also recorded. At least 1 APL was identified in 23 (12.8%) of 179 specimens including invasive lobular carcinoma (n = 3), DCIS (n = 1), ADH/FEA (n = 9) and lobular carcinoma in situ/ALH (n = 10). The most common APL in this cohort was lobular neoplasia (5.6%) followed by ADH and FEA (5.0%). Invasive carcinoma and DCIS was identified in 2.3% of this cohort. In conclusion, the frequency of detection of APLs in patients with history of breast cancer is significantly higher than that in patients without history of breast cancer (12.8% versus 4.3%). Our data assessed the prevalence of APLs in this setting and, therefore, provide new information on decision-making for contralateral breast reduction in patients with history of breast cancer.</AbstractText><CopyrightInformation>© 2013.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Zaibo</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Department of Pathology, Magee-Womens Hospital of the UPMC, Pittsburgh, PA 15213, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fadare</LastName><ForeName>Oluwole</ForeName><Initials>O</Initials></Author><Author ValidYN="Y"><LastName>Hameed</LastName><ForeName>Omar</ForeName><Initials>O</Initials></Author><Author ValidYN="Y"><LastName>Zhao</LastName><ForeName>Chengquan</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Desouki</LastName><ForeName>Mohamed Mokhtar</ForeName><Initials>MM</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>10</Month><Day>31</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Hum Pathol</MedlineTA><NlmUniqueID>9421547</NlmUniqueID><ISSNLinking>0046-8177</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001943" MajorTopicYN="N">Breast Neoplasms</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002278" MajorTopicYN="N">Carcinoma in Situ</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018270" MajorTopicYN="N">Carcinoma, Ductal, Breast</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002285" MajorTopicYN="N">Carcinoma, Intraductal, Noninfiltrating</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018275" MajorTopicYN="N">Carcinoma, Lobular</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D049109" MajorTopicYN="N">Cell Proliferation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D033162" MajorTopicYN="N">Incidental Findings</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016462" MajorTopicYN="N">Mammaplasty</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011230" MajorTopicYN="N">Precancerous Conditions</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Atypical proliferative lesions</Keyword><Keyword MajorTopicYN="N">History of breast cancer</Keyword><Keyword MajorTopicYN="N">Macromastia</Keyword><Keyword MajorTopicYN="N">Occult breast carcinoma</Keyword><Keyword MajorTopicYN="N">Reduction mammoplasty</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year><Month>06</Month><Day>14</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2013</Year><Month>07</Month><Day>31</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2013</Year><Month>08</Month><Day>14</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>11</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>11</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>2</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">24182561</ArticleId><ArticleId IdType="pii">S0046-8177(13)00350-X</ArticleId><ArticleId IdType="doi">10.1016/j.humpath.2013.08.010</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Pennsylvanie</li></region></list><tree><noCountry><name sortKey="Desouki, Mohamed Mokhtar" sort="Desouki, Mohamed Mokhtar" uniqKey="Desouki M" first="Mohamed Mokhtar" last="Desouki">Mohamed Mokhtar Desouki</name><name sortKey="Fadare, Oluwole" sort="Fadare, Oluwole" uniqKey="Fadare O" first="Oluwole" last="Fadare">Oluwole Fadare</name><name sortKey="Hameed, Omar" sort="Hameed, Omar" uniqKey="Hameed O" first="Omar" last="Hameed">Omar Hameed</name><name sortKey="Zhao, Chengquan" sort="Zhao, Chengquan" uniqKey="Zhao C" first="Chengquan" last="Zhao">Chengquan Zhao</name></noCountry><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Li, Zaibo" sort="Li, Zaibo" uniqKey="Li Z" first="Zaibo" last="Li">Zaibo Li</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Amérique/explor/PittsburghV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002749 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 002749 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Amérique
|area= PittsburghV1
|flux= PubMed
|étape= Checkpoint
|type= RBID
|clé= pubmed:24182561
|texte= Incidental atypical proliferative lesions in reduction mammoplasty specimens in patients with a history of breast cancer.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:24182561" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a PittsburghV1
| This area was generated with Dilib version V0.6.38. |  |