Prediction of acute respiratory disease in current and former smokers with and without COPD.
Identifieur interne : 001B62 ( PubMed/Checkpoint ); précédent : 001B61; suivant : 001B63Prediction of acute respiratory disease in current and former smokers with and without COPD.
Auteurs : Russell P. Bowler [États-Unis] ; Victor Kim ; Elizabeth Regan [États-Unis] ; André A A. Williams [États-Unis] ; Stephanie A. Santorico [États-Unis] ; Barry J. Make [États-Unis] ; David A. Lynch [États-Unis] ; John E. Hokanson [États-Unis] ; George R. Washko [États-Unis] ; Peter Bercz ; Xavier Soler [États-Unis] ; Nathaniel Marchetti ; Gerard J. Criner ; Joe Ramsdell [États-Unis] ; Meilan K. Han [États-Unis] ; Dawn Demeo [États-Unis] ; Antonio Anzueto [États-Unis] ; Alejandro Comellas [États-Unis] ; James D. Crapo [États-Unis] ; Mark Dransfield [États-Unis] ; J Michael Wells [États-Unis] ; Craig P. Hersh [États-Unis] ; Neil Macintyre [États-Unis] ; Fernando Martinez [États-Unis] ; Hrudaya P. Nath [États-Unis] ; Dennis Niewoehner [États-Unis] ; Frank Sciurba [États-Unis] ; Amir Sharafkhaneh [États-Unis] ; Edwin K. Silverman [États-Unis] ; Edwin J R. Van Beek [Royaume-Uni] ; Carla Wilson [États-Unis] ; Christine Wendt [États-Unis] ; Robert A. Wise [États-Unis]Source :
- Chest [ 1931-3543 ] ; 2014.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Broncho-pneumopathie chronique obstructive (), Broncho-pneumopathie chronique obstructive (diagnostic), Facteurs de risque, Femelle, Hospitalisation (), Humains, Incidence, Maladie aigüe, Maladies de l'appareil respiratoire (diagnostic), Maladies de l'appareil respiratoire (étiologie), Modèles de hasards proportionnels, Mâle, Qualité de vie, Sujet âgé, Tabagisme (effets indésirables), États-Unis d'Amérique, Études de suivi, Études longitudinales.
- MESH :
- diagnostic : Broncho-pneumopathie chronique obstructive, Maladies de l'appareil respiratoire.
- effets indésirables : Tabagisme.
- étiologie : Maladies de l'appareil respiratoire.
- Adulte d'âge moyen, Broncho-pneumopathie chronique obstructive, Facteurs de risque, Femelle, Hospitalisation, Humains, Incidence, Maladie aigüe, Modèles de hasards proportionnels, Mâle, Qualité de vie, Sujet âgé, États-Unis d'Amérique, Études de suivi, Études longitudinales.
- Wicri :
- geographic : États-Unis.
English descriptors
- KwdEn :
- Acute Disease, Aged, Female, Follow-Up Studies, Hospitalization (statistics & numerical data), Humans, Incidence, Longitudinal Studies, Male, Middle Aged, Proportional Hazards Models, Pulmonary Disease, Chronic Obstructive (complications), Pulmonary Disease, Chronic Obstructive (diagnosis), Quality of Life, Respiratory Tract Diseases (diagnosis), Respiratory Tract Diseases (etiology), Risk Factors, Smoking (adverse effects), United States.
- MESH :
- geographic : United States.
- adverse effects : Smoking.
- complications : Pulmonary Disease, Chronic Obstructive.
- diagnosis : Pulmonary Disease, Chronic Obstructive, Respiratory Tract Diseases.
- etiology : Respiratory Tract Diseases.
- statistics & numerical data : Hospitalization.
- Acute Disease, Aged, Female, Follow-Up Studies, Humans, Incidence, Longitudinal Studies, Male, Middle Aged, Proportional Hazards Models, Quality of Life, Risk Factors.
Abstract
The risk factors for acute episodes of respiratory disease in current and former smokers who do not have COPD are unknown.
DOI: 10.1378/chest.13-2946
PubMed: 24945159
Affiliations:
- Royaume-Uni, États-Unis
- Alabama, Californie, Caroline du Nord, Colorado, Iowa, Maryland, Massachusetts, Michigan, Minnesota, Pennsylvanie, Texas, Écosse
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:24945159Le document en format XML
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<author><name sortKey="Niewoehner, Dennis" sort="Niewoehner, Dennis" uniqKey="Niewoehner D" first="Dennis" last="Niewoehner">Dennis Niewoehner</name>
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<author><name sortKey="Sciurba, Frank" sort="Sciurba, Frank" uniqKey="Sciurba F" first="Frank" last="Sciurba">Frank Sciurba</name>
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<author><name sortKey="Sharafkhaneh, Amir" sort="Sharafkhaneh, Amir" uniqKey="Sharafkhaneh A" first="Amir" last="Sharafkhaneh">Amir Sharafkhaneh</name>
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<author><name sortKey="Van Beek, Edwin J R" sort="Van Beek, Edwin J R" uniqKey="Van Beek E" first="Edwin J R" last="Van Beek">Edwin J R. Van Beek</name>
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<author><name sortKey="Wilson, Carla" sort="Wilson, Carla" uniqKey="Wilson C" first="Carla" last="Wilson">Carla Wilson</name>
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<author><name sortKey="Wendt, Christine" sort="Wendt, Christine" uniqKey="Wendt C" first="Christine" last="Wendt">Christine Wendt</name>
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<author><name sortKey="Wise, Robert A" sort="Wise, Robert A" uniqKey="Wise R" first="Robert A" last="Wise">Robert A. Wise</name>
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<author><name sortKey="Make, Barry J" sort="Make, Barry J" uniqKey="Make B" first="Barry J" last="Make">Barry J. Make</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Colorado</region>
</placeName>
<wicri:cityArea>Department of Medicine, National Jewish Health, Denver</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hokanson, John E" sort="Hokanson, John E" uniqKey="Hokanson J" first="John E" last="Hokanson">John E. Hokanson</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine and the Department of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora, CO.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Colorado</region>
</placeName>
<wicri:cityArea>Department of Medicine and the Department of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Washko, George R" sort="Washko, George R" uniqKey="Washko G" first="George R" last="Washko">George R. Washko</name>
<affiliation wicri:level="2"><nlm:affiliation>Channing Division of Network Medicine, Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital, Boston, MA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Channing Division of Network Medicine, Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Bercz, Peter" sort="Bercz, Peter" uniqKey="Bercz P" first="Peter" last="Bercz">Peter Bercz</name>
<affiliation><nlm:affiliation>Department of Medicine, Section of Pulmonary and Critical Care Medicine, Temple University, Philadelphia PA.</nlm:affiliation>
<wicri:noCountry code="subField">Philadelphia PA</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Soler, Xavier" sort="Soler, Xavier" uniqKey="Soler X" first="Xavier" last="Soler">Xavier Soler</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California at San Diego, La Jolla, CA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California at San Diego, La Jolla</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Marchetti, Nathaniel" sort="Marchetti, Nathaniel" uniqKey="Marchetti N" first="Nathaniel" last="Marchetti">Nathaniel Marchetti</name>
<affiliation><nlm:affiliation>Department of Medicine, Section of Pulmonary and Critical Care Medicine, Temple University, Philadelphia PA.</nlm:affiliation>
<wicri:noCountry code="subField">Philadelphia PA</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Criner, Gerard J" sort="Criner, Gerard J" uniqKey="Criner G" first="Gerard J" last="Criner">Gerard J. Criner</name>
<affiliation><nlm:affiliation>Department of Medicine, Section of Pulmonary and Critical Care Medicine, Temple University, Philadelphia PA.</nlm:affiliation>
<wicri:noCountry code="subField">Philadelphia PA</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Ramsdell, Joe" sort="Ramsdell, Joe" uniqKey="Ramsdell J" first="Joe" last="Ramsdell">Joe Ramsdell</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California at San Diego, La Jolla, CA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California at San Diego, La Jolla</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Han, Meilan K" sort="Han, Meilan K" uniqKey="Han M" first="Meilan K" last="Han">Meilan K. Han</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Internal Medicine, University of Michigan, Ann Arbor, MI.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Michigan</region>
</placeName>
<wicri:cityArea>Department of Internal Medicine, University of Michigan, Ann Arbor</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Demeo, Dawn" sort="Demeo, Dawn" uniqKey="Demeo D" first="Dawn" last="Demeo">Dawn Demeo</name>
<affiliation wicri:level="2"><nlm:affiliation>Channing Division of Network Medicine, Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital, Boston, MA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Channing Division of Network Medicine, Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Anzueto, Antonio" sort="Anzueto, Antonio" uniqKey="Anzueto A" first="Antonio" last="Anzueto">Antonio Anzueto</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Texas Health Science Center, and South Texas Veterans Health Care System, San Antonio, TX.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Texas</region>
</placeName>
<wicri:cityArea>Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Texas Health Science Center, and South Texas Veterans Health Care System, San Antonio</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Comellas, Alejandro" sort="Comellas, Alejandro" uniqKey="Comellas A" first="Alejandro" last="Comellas">Alejandro Comellas</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Iowa, Iowa City, IA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Iowa</region>
</placeName>
<wicri:cityArea>University of Iowa, Iowa City</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Crapo, James D" sort="Crapo, James D" uniqKey="Crapo J" first="James D" last="Crapo">James D. Crapo</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, National Jewish Health, Denver, CO.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Colorado</region>
</placeName>
<wicri:cityArea>Department of Medicine, National Jewish Health, Denver</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Dransfield, Mark" sort="Dransfield, Mark" uniqKey="Dransfield M" first="Mark" last="Dransfield">Mark Dransfield</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Alabama at Birmingham, Birmingham, AL.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea>University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Wells, J Michael" sort="Wells, J Michael" uniqKey="Wells J" first="J Michael" last="Wells">J Michael Wells</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Alabama at Birmingham, Birmingham, AL.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea>University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hersh, Craig P" sort="Hersh, Craig P" uniqKey="Hersh C" first="Craig P" last="Hersh">Craig P. Hersh</name>
<affiliation wicri:level="2"><nlm:affiliation>Channing Division of Network Medicine, Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital, Boston, MA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Channing Division of Network Medicine, Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Macintyre, Neil" sort="Macintyre, Neil" uniqKey="Macintyre N" first="Neil" last="Macintyre">Neil Macintyre</name>
<affiliation wicri:level="2"><nlm:affiliation>Duke University Medical Center, Durham, NC.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
<wicri:cityArea>Duke University Medical Center, Durham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Martinez, Fernando" sort="Martinez, Fernando" uniqKey="Martinez F" first="Fernando" last="Martinez">Fernando Martinez</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Internal Medicine, University of Michigan, Ann Arbor, MI.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Michigan</region>
</placeName>
<wicri:cityArea>Department of Internal Medicine, University of Michigan, Ann Arbor</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Nath, Hrudaya P" sort="Nath, Hrudaya P" uniqKey="Nath H" first="Hrudaya P" last="Nath">Hrudaya P. Nath</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Alabama at Birmingham, Birmingham, AL.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea>University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Niewoehner, Dennis" sort="Niewoehner, Dennis" uniqKey="Niewoehner D" first="Dennis" last="Niewoehner">Dennis Niewoehner</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Minnesota, Minneapolis, MN.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Minnesota</region>
</placeName>
<wicri:cityArea>University of Minnesota, Minneapolis</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Sciurba, Frank" sort="Sciurba, Frank" uniqKey="Sciurba F" first="Frank" last="Sciurba">Frank Sciurba</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Pittsburgh Medical Center, Pittsburgh, PA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>University of Pittsburgh Medical Center, Pittsburgh</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Sharafkhaneh, Amir" sort="Sharafkhaneh, Amir" uniqKey="Sharafkhaneh A" first="Amir" last="Sharafkhaneh">Amir Sharafkhaneh</name>
<affiliation wicri:level="2"><nlm:affiliation>Baylor College of Medicine, Houston, TX.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Texas</region>
</placeName>
<wicri:cityArea>Baylor College of Medicine, Houston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Silverman, Edwin K" sort="Silverman, Edwin K" uniqKey="Silverman E" first="Edwin K" last="Silverman">Edwin K. Silverman</name>
<affiliation wicri:level="2"><nlm:affiliation>Channing Division of Network Medicine, Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital, Boston, MA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>Channing Division of Network Medicine, Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Van Beek, Edwin J R" sort="Van Beek, Edwin J R" uniqKey="Van Beek E" first="Edwin J R" last="Van Beek">Edwin J R. Van Beek</name>
<affiliation wicri:level="2"><nlm:affiliation>Clinical Research Imaging Centre, University of Edinburgh, Edinburgh, Scotland.</nlm:affiliation>
<country>Royaume-Uni</country>
<placeName><region type="country">Écosse</region>
</placeName>
<wicri:cityArea>Clinical Research Imaging Centre, University of Edinburgh, Edinburgh</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Wilson, Carla" sort="Wilson, Carla" uniqKey="Wilson C" first="Carla" last="Wilson">Carla Wilson</name>
<affiliation wicri:level="2"><nlm:affiliation>Division of Biostatistics and Bioinformatics, National Jewish Health, Denver, CO.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Colorado</region>
</placeName>
<wicri:cityArea>Division of Biostatistics and Bioinformatics, National Jewish Health, Denver</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Wendt, Christine" sort="Wendt, Christine" uniqKey="Wendt C" first="Christine" last="Wendt">Christine Wendt</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Minnesota, Minneapolis, MN.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Minnesota</region>
</placeName>
<wicri:cityArea>University of Minnesota, Minneapolis</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Wise, Robert A" sort="Wise, Robert A" uniqKey="Wise R" first="Robert A" last="Wise">Robert A. Wise</name>
<affiliation wicri:level="2"><nlm:affiliation>Johns Hopkins University, Baltimore, MD.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Maryland</region>
</placeName>
<wicri:cityArea>Johns Hopkins University, Baltimore</wicri:cityArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Chest</title>
<idno type="eISSN">1931-3543</idno>
<imprint><date when="2014" type="published">2014</date>
</imprint>
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<term>Aged</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Hospitalization (statistics & numerical data)</term>
<term>Humans</term>
<term>Incidence</term>
<term>Longitudinal Studies</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Proportional Hazards Models</term>
<term>Pulmonary Disease, Chronic Obstructive (complications)</term>
<term>Pulmonary Disease, Chronic Obstructive (diagnosis)</term>
<term>Quality of Life</term>
<term>Respiratory Tract Diseases (diagnosis)</term>
<term>Respiratory Tract Diseases (etiology)</term>
<term>Risk Factors</term>
<term>Smoking (adverse effects)</term>
<term>United States</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Broncho-pneumopathie chronique obstructive ()</term>
<term>Broncho-pneumopathie chronique obstructive (diagnostic)</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Hospitalisation ()</term>
<term>Humains</term>
<term>Incidence</term>
<term>Maladie aigüe</term>
<term>Maladies de l'appareil respiratoire (diagnostic)</term>
<term>Maladies de l'appareil respiratoire (étiologie)</term>
<term>Modèles de hasards proportionnels</term>
<term>Mâle</term>
<term>Qualité de vie</term>
<term>Sujet âgé</term>
<term>Tabagisme (effets indésirables)</term>
<term>États-Unis d'Amérique</term>
<term>Études de suivi</term>
<term>Études longitudinales</term>
</keywords>
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</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Smoking</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Pulmonary Disease, Chronic Obstructive</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Pulmonary Disease, Chronic Obstructive</term>
<term>Respiratory Tract Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Broncho-pneumopathie chronique obstructive</term>
<term>Maladies de l'appareil respiratoire</term>
</keywords>
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</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Respiratory Tract Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Hospitalization</term>
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</keywords>
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<term>Aged</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Incidence</term>
<term>Longitudinal Studies</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Proportional Hazards Models</term>
<term>Quality of Life</term>
<term>Risk Factors</term>
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<term>Broncho-pneumopathie chronique obstructive</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Hospitalisation</term>
<term>Humains</term>
<term>Incidence</term>
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<front><div type="abstract" xml:lang="en">The risk factors for acute episodes of respiratory disease in current and former smokers who do not have COPD are unknown.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24945159</PMID>
<DateCreated><Year>2014</Year>
<Month>10</Month>
<Day>07</Day>
</DateCreated>
<DateCompleted><Year>2014</Year>
<Month>12</Month>
<Day>04</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>05</Month>
<Day>22</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1931-3543</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>146</Volume>
<Issue>4</Issue>
<PubDate><Year>2014</Year>
<Month>Oct</Month>
</PubDate>
</JournalIssue>
<Title>Chest</Title>
<ISOAbbreviation>Chest</ISOAbbreviation>
</Journal>
<ArticleTitle>Prediction of acute respiratory disease in current and former smokers with and without COPD.</ArticleTitle>
<Pagination><MedlinePgn>941-950</MedlinePgn>
</Pagination>
<ELocationID EIdType="pii" ValidYN="Y">S0012-3692(15)33176-7</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1378/chest.13-2946</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The risk factors for acute episodes of respiratory disease in current and former smokers who do not have COPD are unknown.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Eight thousand two hundred forty-six non-Hispanic white and black current and former smokers in the Genetic Epidemiology of COPD (COPDGene) cohort had longitudinal follow-up (LFU) every 6 months to determine acute respiratory episodes requiring antibiotics or systemic corticosteroids, an ED visit, or hospitalization. Negative binomial regression was used to determine the factors associated with acute respiratory episodes. A Cox proportional hazards model was used to determine adjusted hazard ratios (HRs) for time to first episode and an acute episode of respiratory disease risk score.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">At enrollment, 4,442 subjects did not have COPD, 658 had mild COPD, and 3,146 had moderate or worse COPD. Nine thousand three hundred three acute episodes of respiratory disease and 2,707 hospitalizations were reported in LFU (3,044 acute episodes of respiratory disease and 827 hospitalizations in those without COPD). Major predictors included acute episodes of respiratory disease in year prior to enrollment (HR, 1.20; 95% CI, 1.15-1.24 per exacerbation), airflow obstruction (HR, 0.94; 95% CI, 0.91-0.96 per 10% change in % predicted FEV1), and poor health-related quality of life (HR, 1.07; 95% CI, 1.06-1.08 for each 4-unit increase in St. George's Respiratory Questionnaire score). Risks were similar for those with and without COPD.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Although acute episode of respiratory disease rates are higher in subjects with COPD, risk factors are similar, and at a population level, there are more episodes in smokers without COPD.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bowler</LastName>
<ForeName>Russell P</ForeName>
<Initials>RP</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, National Jewish Health, Denver, CO. Electronic address: Bowlerr@njhealth.org.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kim</LastName>
<ForeName>Victor</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Section of Pulmonary and Critical Care Medicine, Temple University, Philadelphia PA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Regan</LastName>
<ForeName>Elizabeth</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, National Jewish Health, Denver, CO.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Williams</LastName>
<ForeName>André A A</ForeName>
<Initials>AAA</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, National Jewish Health, Denver, CO.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Santorico</LastName>
<ForeName>Stephanie A</ForeName>
<Initials>SA</Initials>
<AffiliationInfo><Affiliation>Department of Mathematical and Statistical Sciences, University of Colorado Denver, Denver, CO.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Make</LastName>
<ForeName>Barry J</ForeName>
<Initials>BJ</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, National Jewish Health, Denver, CO.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lynch</LastName>
<ForeName>David A</ForeName>
<Initials>DA</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, National Jewish Health, Denver, CO.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hokanson</LastName>
<ForeName>John E</ForeName>
<Initials>JE</Initials>
<AffiliationInfo><Affiliation>Department of Medicine and the Department of Epidemiology, University of Colorado Anschutz Medical Campus, Aurora, CO.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Washko</LastName>
<ForeName>George R</ForeName>
<Initials>GR</Initials>
<AffiliationInfo><Affiliation>Channing Division of Network Medicine, Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital, Boston, MA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bercz</LastName>
<ForeName>Peter</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Section of Pulmonary and Critical Care Medicine, Temple University, Philadelphia PA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Soler</LastName>
<ForeName>Xavier</ForeName>
<Initials>X</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California at San Diego, La Jolla, CA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Marchetti</LastName>
<ForeName>Nathaniel</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Section of Pulmonary and Critical Care Medicine, Temple University, Philadelphia PA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Criner</LastName>
<ForeName>Gerard J</ForeName>
<Initials>GJ</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Section of Pulmonary and Critical Care Medicine, Temple University, Philadelphia PA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ramsdell</LastName>
<ForeName>Joe</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California at San Diego, La Jolla, CA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Han</LastName>
<ForeName>MeiLan K</ForeName>
<Initials>MK</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine, University of Michigan, Ann Arbor, MI.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Demeo</LastName>
<ForeName>Dawn</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Channing Division of Network Medicine, Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital, Boston, MA.</Affiliation>
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