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Bipolar I and II versus unipolar depression: clinical differences and impulsivity/aggression traits.

Identifieur interne : 000897 ( PubMed/Checkpoint ); précédent : 000896; suivant : 000898

Bipolar I and II versus unipolar depression: clinical differences and impulsivity/aggression traits.

Auteurs : K. Dervic [Émirats arabes unis] ; M. Garcia-Amador [Espagne] ; K. Sudol [États-Unis] ; P. Freed [États-Unis] ; D A Brent [États-Unis] ; J J Mann [États-Unis] ; J M Harkavy-Friedman [États-Unis] ; M A Oquendo [États-Unis]

Source :

RBID : pubmed:25280430

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English descriptors

Abstract

To investigate distinguishing features between bipolar I, II and unipolar depression, and impulsivity/aggression traits in particular.

DOI: 10.1016/j.eurpsy.2014.06.005
PubMed: 25280430


Affiliations:


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pubmed:25280430

Le document en format XML

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<term>Comorbidity</term>
<term>Depressive Disorder (psychology)</term>
<term>Depressive Disorder, Major (psychology)</term>
<term>Female</term>
<term>Humans</term>
<term>Impulsive Behavior</term>
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<term>Adulte d'âge moyen</term>
<term>Agressivité</term>
<term>Comorbidité</term>
<term>Comportement impulsif</term>
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<div type="abstract" xml:lang="en">To investigate distinguishing features between bipolar I, II and unipolar depression, and impulsivity/aggression traits in particular.</div>
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<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To investigate distinguishing features between bipolar I, II and unipolar depression, and impulsivity/aggression traits in particular.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Six hundred and eighty-five (n=685) patients in a major depressive episode with lifetime Unipolar (UP) depression (n=455), Bipolar I (BP-I) disorder (n=151), and Bipolar II (BP-II) (n=79) disorder were compared in terms of their socio-demographic and clinical characteristics.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Compared to unipolar patients, BP-I and BP-II depressed patients were significantly younger at onset of their first depressive episode, and were more likely to experience their first depressive episode before/at age of 15. They also had more previous affective episodes, more first- and second-degree relatives with history of mania, more current psychotic and subsyndromal manic symptoms, and received psychopharmacological and psychotherapy treatment at an earlier age. Furthermore, BP-I and BP-II depressed patients had higher lifetime impulsivity, aggression, and hostility scores. With regard to bipolar subtypes, BP-I patients had more trait-impulsivity and lifetime aggression than BP-II patients whereas the latter had more hostility than BP-I patients. As for co-morbid disorders, Cluster A and B Personality Disorders, alcohol and substance abuse/dependence and anxiety disorders were more prevalent in BP-I and BP-II than in unipolar patients. Whereas the three groups did not differ on other socio-demographic variables, BP-I patients were significantly more often unemployed that UP patients.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Our findings comport with major previous findings on differences between bipolar and unipolar depression. As for trait characteristics, bipolar I and II depressed patients had more life-time impulsivity and aggression/hostility than unipolar patients. In addition, bipolar I and II patients also differed on these trait characteristics.</AbstractText>
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