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Nonmedically indicated induction vs expectant treatment in term nulliparous women.

Identifieur interne : 000430 ( PubMed/Checkpoint ); précédent : 000429; suivant : 000431

Nonmedically indicated induction vs expectant treatment in term nulliparous women.

Auteurs : Jennifer L. Bailit [États-Unis] ; William Grobman [États-Unis] ; Yuan Zhao [États-Unis] ; Ronald J. Wapner [États-Unis] ; Uma M. Reddy [États-Unis] ; Michael W. Varner [États-Unis] ; Kenneth J. Leveno [États-Unis] ; Steve N. Caritis [États-Unis] ; Jay D. Iams [États-Unis] ; Alan T. Tita [États-Unis] ; George Saade [États-Unis] ; Yoram Sorokin [États-Unis] ; Dwight J. Rouse [États-Unis] ; Sean C. Blackwell [États-Unis] ; Jorge E. Tolosa [États-Unis] ; J Peter Vandorsten [États-Unis]

Source :

RBID : pubmed:24983681

Descripteurs français

English descriptors

Abstract

The purpose of this study was to compare maternal and neonatal outcomes in nulliparous women with nonmedically indicated inductions at term vs those expectantly treated.

DOI: 10.1016/j.ajog.2014.06.054
PubMed: 24983681


Affiliations:


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pubmed:24983681

Le document en format XML

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<term>Humans</term>
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<term>Femelle</term>
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<term>Humains</term>
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<term>Jeune adulte</term>
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<div type="abstract" xml:lang="en">The purpose of this study was to compare maternal and neonatal outcomes in nulliparous women with nonmedically indicated inductions at term vs those expectantly treated.</div>
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<Abstract>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The purpose of this study was to compare maternal and neonatal outcomes in nulliparous women with nonmedically indicated inductions at term vs those expectantly treated.</AbstractText>
<AbstractText Label="STUDY DESIGN" NlmCategory="METHODS">Data were obtained from maternal and neonatal charts for all deliveries on randomly selected days across 25 US hospitals over a 3-year period. A low-risk subset of nulliparous women with vertex nonanomalous singleton gestations who delivered 38 0/7 to 41 6/7 weeks were selected. Maternal and neonatal outcomes for nonmedically indicated induction within each week were compared with women who did not undergo nonmedically indicated induction during that week. Multivariable analysis was used to adjust for hospital, maternal age, race/ethnicity, body mass index, cigarette use, and insurance status.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">We found 31,169 women who met our criteria. Neonatal complications were either less frequent with nonmedically indicated induction or no different between groups. Nonmedically indicated induction was associated with less frequent peripartum infections (odds ratio [OR], 0.39; 95% confidence interval [CI], 0.16-0.98) at 38 weeks of gestation and less frequent third- and fourth-degree lacerations (OR, 0.60; 95% CI, 0.42-0.86) and less frequent peripartum infections (OR, 0.66; 95% CI, 0.49-0.90) at 39 weeks of gestation. Nonmedically indicated induction was associated with a longer admission-to-delivery time by approximately 3-4 hours and increased odds of cesarean delivery at 38 (OR, 1.50; 95% CI, 1.08-2.08) and 40 weeks (OR, 1.30; 95% CI, 1.15-1.46) of gestation.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">At 39 weeks of gestation, nonmedically indicated induction is associated with lower maternal and neonatal morbidity than women who are expectantly treated.</AbstractText>
<CopyrightInformation>Copyright © 2015 Elsevier Inc. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Bailit</LastName>
<ForeName>Jennifer L</ForeName>
<Initials>JL</Initials>
<AffiliationInfo>
<Affiliation>Departments of Obstetrics and Gynecology of: Case Western Reserve University-MetroHealth Medical Center, Cleveland, OH. Electronic address: jbailit@metrohealth.org.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Grobman</LastName>
<ForeName>William</ForeName>
<Initials>W</Initials>
<AffiliationInfo>
<Affiliation>Prentice Women's Hospital, Northwestern University, Chicago, IL.</Affiliation>
</AffiliationInfo>
</Author>
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<LastName>Zhao</LastName>
<ForeName>Yuan</ForeName>
<Initials>Y</Initials>
<AffiliationInfo>
<Affiliation>Biostatistics Center, George Washington University, Washington, DC.</Affiliation>
</AffiliationInfo>
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<LastName>Wapner</LastName>
<ForeName>Ronald J</ForeName>
<Initials>RJ</Initials>
<AffiliationInfo>
<Affiliation>College of Physicians and Surgeons, Columbia University, New York, NY.</Affiliation>
</AffiliationInfo>
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<ForeName>Uma M</ForeName>
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</AffiliationInfo>
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<ForeName>Michael W</ForeName>
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<Affiliation>University of Utah Health Sciences Center, Salt Lake City, UT.</Affiliation>
</AffiliationInfo>
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<ForeName>Kenneth J</ForeName>
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<Affiliation>University of Texas Southwestern Medical Center, Dallas, TX.</Affiliation>
</AffiliationInfo>
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<ForeName>Steve N</ForeName>
<Initials>SN</Initials>
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<ForeName>Alan T</ForeName>
<Initials>AT</Initials>
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<Affiliation>University of Alabama at Birmingham School of Medicine, Birmingham, AL.</Affiliation>
</AffiliationInfo>
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<LastName>Saade</LastName>
<ForeName>George</ForeName>
<Initials>G</Initials>
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<Affiliation>University of Texas Medical Branch, Galveston, TX.</Affiliation>
</AffiliationInfo>
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<LastName>Sorokin</LastName>
<ForeName>Yoram</ForeName>
<Initials>Y</Initials>
<AffiliationInfo>
<Affiliation>Wayne State University School of Medicine, Detroit, MI.</Affiliation>
</AffiliationInfo>
</Author>
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<ForeName>Dwight J</ForeName>
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<AffiliationInfo>
<Affiliation>The Warren Alpert Medical School of Brown University, Providence, RI.</Affiliation>
</AffiliationInfo>
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<LastName>Blackwell</LastName>
<ForeName>Sean C</ForeName>
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</AffiliationInfo>
</Author>
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<LastName>Tolosa</LastName>
<ForeName>Jorge E</ForeName>
<Initials>JE</Initials>
<AffiliationInfo>
<Affiliation>Oregon Health & Science University, Portland, OR.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>VanDorsten</LastName>
<ForeName>J Peter</ForeName>
<Initials>JP</Initials>
<AffiliationInfo>
<Affiliation>Medical University of South Carolina, Charleston, SC.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<CollectiveName>Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units (MFMU) Network</CollectiveName>
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<MeshHeadingList>
<MeshHeading>
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</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<MeshHeading>
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<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
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<MeshHeading>
<DescriptorName UI="D011256" MajorTopicYN="N">Pregnancy Outcome</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D047929" MajorTopicYN="Y">Term Birth</DescriptorName>
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<OtherID Source="NLM">NIHMS624389</OtherID>
<OtherID Source="NLM">PMC4275393</OtherID>
<KeywordList Owner="NOTNLM">
<Keyword MajorTopicYN="N">induction</Keyword>
<Keyword MajorTopicYN="N">nonmedically indicated induction</Keyword>
<Keyword MajorTopicYN="N">nulliparous women</Keyword>
</KeywordList>
<InvestigatorList>
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<LastName>Mercer</LastName>
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<Initials>B</Initials>
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<Initials>W</Initials>
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<ForeName>T</ForeName>
<Initials>T</Initials>
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<LastName>McDonald</LastName>
<ForeName>P</ForeName>
<Initials>P</Initials>
</Investigator>
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<LastName>Brezine</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
</Investigator>
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<LastName>McGrail</LastName>
<ForeName>A</ForeName>
<Initials>A</Initials>
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<LastName>Mallett</LastName>
<ForeName>G</ForeName>
<Initials>G</Initials>
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<ForeName>M</ForeName>
<Initials>M</Initials>
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<Initials>A</Initials>
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<LastName>Stein</LastName>
<ForeName>L</ForeName>
<Initials>L</Initials>
</Investigator>
<Investigator ValidYN="Y">
<LastName>Campbell</LastName>
<ForeName>P</ForeName>
<Initials>P</Initials>
</Investigator>
<Investigator ValidYN="Y">
<LastName>Collins</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
</Investigator>
<Investigator ValidYN="Y">
<LastName>Jackson</LastName>
<ForeName>N</ForeName>
<Initials>N</Initials>
</Investigator>
<Investigator ValidYN="Y">
<LastName>Dinsmoor</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
</Investigator>
<Investigator ValidYN="Y">
<LastName>Senka</LastName>
<ForeName>J</ForeName>
<Initials>J</Initials>
</Investigator>
<Investigator ValidYN="Y">
<LastName>Paychek</LastName>
<ForeName>K</ForeName>
<Initials>K</Initials>
</Investigator>
<Investigator ValidYN="Y">
<LastName>Peaceman</LastName>
<ForeName>A</ForeName>
<Initials>A</Initials>
</Investigator>
<Investigator ValidYN="Y">
<LastName>Talucci</LastName>
<ForeName>M</ForeName>
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