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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Role of cardiovascular intervention as a bridge to liver transplantation</title><author><name sortKey="Raval, Zankhana" sort="Raval, Zankhana" uniqKey="Raval Z" first="Zankhana" last="Raval">Zankhana Raval</name></author><author><name sortKey="Harinstein, Matthew E" sort="Harinstein, Matthew E" uniqKey="Harinstein M" first="Matthew E" last="Harinstein">Matthew E. Harinstein</name></author><author><name sortKey="Flaherty, James D" sort="Flaherty, James D" uniqKey="Flaherty J" first="James D" last="Flaherty">James D. Flaherty</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25152569</idno><idno type="pmc">4138446</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138446</idno><idno type="RBID">PMC:4138446</idno><idno type="doi">10.3748/wjg.v20.i31.10651</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">001F16</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001F16</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Role of cardiovascular intervention as a bridge to liver transplantation</title><author><name sortKey="Raval, Zankhana" sort="Raval, Zankhana" uniqKey="Raval Z" first="Zankhana" last="Raval">Zankhana Raval</name></author><author><name sortKey="Harinstein, Matthew E" sort="Harinstein, Matthew E" uniqKey="Harinstein M" first="Matthew E" last="Harinstein">Matthew E. Harinstein</name></author><author><name sortKey="Flaherty, James D" sort="Flaherty, James D" uniqKey="Flaherty J" first="James D" last="Flaherty">James D. Flaherty</name></author></analytic><series><title level="j">World Journal of Gastroenterology : WJG</title><idno type="ISSN">1007-9327</idno><idno type="eISSN">2219-2840</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>End stage liver disease (ESLD) is associated with many specific derangements in cardiovascular physiology, which influence perioperative outcomes and may profoundly influence diagnostic and management strategies in the preoperative period. This review focuses on evidence-based diagnosis and management of coronary, hemodynamic and pulmonary vascular disease in this population with an emphasis on specific strategies that may provide a bridge to transplantation. Specifically, we address the underlying prevalence of cardiovascular disease states in the ESLD population, and relevant diagnostic criteria thereof. We highlight traditional and non-traditional predictors of cardiovascular outcomes following liver transplant, as well as data to guide risk-factor based diagnostic strategies. We go on to discuss the alterations in cardiovascular physiology which influence positive- and negative-predictive values of standard noninvasive testing modalities in the ESLD population, and review the data regarding the safety and efficacy of invasive testing in the face of ESLD and its co-morbidities. Finally, based upon the totality of available data, we outline an evidence-based approach for the management of ischemia, heart failure and pulmonary vascular disease in this population. It is our hope that such evidence-driven strategies can be employed to more safely bridge appropriate candidates to liver transplant, and to improve their cardiovascular health and outcomes in the peri-operative period.</p></div></front></TEI><pmc article-type="review-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">World J Gastroenterol</journal-id><journal-id journal-id-type="iso-abbrev">World J. Gastroenterol</journal-id><journal-id journal-id-type="publisher-id">WJG</journal-id><journal-title-group><journal-title>World Journal of Gastroenterology : WJG</journal-title></journal-title-group><issn pub-type="ppub">1007-9327</issn><issn pub-type="epub">2219-2840</issn><publisher><publisher-name>Baishideng Publishing Group Inc</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25152569</article-id><article-id pub-id-type="pmc">4138446</article-id><article-id pub-id-type="other">jWJG.v20.i31.pg10651</article-id><article-id pub-id-type="doi">10.3748/wjg.v20.i31.10651</article-id><article-categories><subj-group subj-group-type="heading"><subject>Topic Highlight</subject></subj-group></article-categories><title-group><article-title>Role of cardiovascular intervention as a bridge to liver transplantation</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Raval</surname><given-names>Zankhana</given-names></name></contrib><contrib contrib-type="author"><name><surname>Harinstein</surname><given-names>Matthew E</given-names></name></contrib><contrib contrib-type="author"><name><surname>Flaherty</surname><given-names>James D</given-names></name></contrib><aff>Zankhana Raval, James D Flaherty, Bluhm Cardiovascular Institute, Feinberg School of Medicine of Northwestern University, Chicago, IL 60611, United States</aff><aff>Matthew E Harinstein, University of Pittsburgh Medical Center Heart and Vascular Institute, Pittsburgh, PA 15219, United States</aff></contrib-group><author-notes><fn><p>Author contributions: Raval Z contributed to the study idea, study design, literature search, and manuscript writing; Harinstein ME contributed to the manuscript writing and final revision of the article; Flaherty JD contributed to the study idea, literature search, manuscript writing and final revision of the article.</p><p>Correspondence to: James D Flaherty, MD, Bluhm Cardiovascular Institute, Feinberg School of Medicine of Northwestern University, 676 North Saint Clair St. Suite 600, Chicago, IL 60611, United States. <email>jflahert@nmh.org</email></p><p>Telephone: +1-312-9268948 Fax: +1-312-6949430</p></fn></author-notes><pub-date pub-type="ppub"><day>21</day><month>8</month><year>2014</year></pub-date><pub-date pub-type="epub"><day>21</day><month>8</month><year>2014</year></pub-date><volume>20</volume><issue>31</issue><fpage>10651</fpage><lpage>10657</lpage><history><date date-type="received"><day>17</day><month>10</month><year>2013</year></date><date date-type="rev-recd"><day>11</day><month>1</month><year>2014</year></date><date date-type="accepted"><day>1</day><month>4</month><year>2014</year></date></history><permissions><copyright-statement>©2014 Baishideng Publishing Group Inc. All rights reserved.</copyright-statement><copyright-year>2014</copyright-year></permissions><abstract><p>End stage liver disease (ESLD) is associated with many specific derangements in cardiovascular physiology, which influence perioperative outcomes and may profoundly influence diagnostic and management strategies in the preoperative period. This review focuses on evidence-based diagnosis and management of coronary, hemodynamic and pulmonary vascular disease in this population with an emphasis on specific strategies that may provide a bridge to transplantation. Specifically, we address the underlying prevalence of cardiovascular disease states in the ESLD population, and relevant diagnostic criteria thereof. We highlight traditional and non-traditional predictors of cardiovascular outcomes following liver transplant, as well as data to guide risk-factor based diagnostic strategies. We go on to discuss the alterations in cardiovascular physiology which influence positive- and negative-predictive values of standard noninvasive testing modalities in the ESLD population, and review the data regarding the safety and efficacy of invasive testing in the face of ESLD and its co-morbidities. Finally, based upon the totality of available data, we outline an evidence-based approach for the management of ischemia, heart failure and pulmonary vascular disease in this population. It is our hope that such evidence-driven strategies can be employed to more safely bridge appropriate candidates to liver transplant, and to improve their cardiovascular health and outcomes in the peri-operative period.</p></abstract><kwd-group><kwd>Perioperative management</kwd><kwd>Liver transplantation</kwd><kwd>Coronary heart disease</kwd><kwd>Cirrhotic cardiomyopathy</kwd><kwd>Heart failure</kwd><kwd>Pulmonary vascular disease</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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