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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Forced-Response Test Does Not Discriminate Ears with Different Otitis Media Expressions</title>
<author><name sortKey="Casselbrant, Margaretha L" sort="Casselbrant, Margaretha L" uniqKey="Casselbrant M" first="Margaretha L." last="Casselbrant">Margaretha L. Casselbrant</name>
</author>
<author><name sortKey="Mandel, Ellen M" sort="Mandel, Ellen M" uniqKey="Mandel E" first="Ellen M." last="Mandel">Ellen M. Mandel</name>
</author>
<author><name sortKey="Seroky, James T" sort="Seroky, James T" uniqKey="Seroky J" first="James T." last="Seroky">James T. Seroky</name>
</author>
<author><name sortKey="Swarts, J Douglas" sort="Swarts, J Douglas" uniqKey="Swarts J" first="J. Douglas" last="Swarts">J. Douglas Swarts</name>
</author>
<author><name sortKey="Doyle, William J" sort="Doyle, William J" uniqKey="Doyle W" first="William J." last="Doyle">William J. Doyle</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">24550093</idno>
<idno type="pmc">4136992</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136992</idno>
<idno type="RBID">PMC:4136992</idno>
<idno type="doi">10.1002/lary.24647</idno>
<date when="2014">2014</date>
<idno type="wicri:Area/Pmc/Corpus">001614</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001614</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Forced-Response Test Does Not Discriminate Ears with Different Otitis Media Expressions</title>
<author><name sortKey="Casselbrant, Margaretha L" sort="Casselbrant, Margaretha L" uniqKey="Casselbrant M" first="Margaretha L." last="Casselbrant">Margaretha L. Casselbrant</name>
</author>
<author><name sortKey="Mandel, Ellen M" sort="Mandel, Ellen M" uniqKey="Mandel E" first="Ellen M." last="Mandel">Ellen M. Mandel</name>
</author>
<author><name sortKey="Seroky, James T" sort="Seroky, James T" uniqKey="Seroky J" first="James T." last="Seroky">James T. Seroky</name>
</author>
<author><name sortKey="Swarts, J Douglas" sort="Swarts, J Douglas" uniqKey="Swarts J" first="J. Douglas" last="Swarts">J. Douglas Swarts</name>
</author>
<author><name sortKey="Doyle, William J" sort="Doyle, William J" uniqKey="Doyle W" first="William J." last="Doyle">William J. Doyle</name>
</author>
</analytic>
<series><title level="j">The Laryngoscope</title>
<idno type="ISSN">0023-852X</idno>
<idno type="eISSN">1531-4995</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objective</title>
<p id="P1">Test the hypothesis that the Eustachian tube (ET) function measured using standard manometric test methods is different between groups of ears with tympanostomy tubes inserted for recurrent acute otitis media (RAOM) and for chronic otitis media with effusion (COME).</p>
</sec>
<sec id="S2"><title>Study Design</title>
<p id="P2">A cross-sectional study of ET function in populations of young children with different otitis media expressions.</p>
</sec>
<sec id="S3"><title>Methods</title>
<p id="P3">The results for Forced-Response testing of ET function were compared using a general linear model between 37 ears of 26 children and 34 ears of 26 children aged 3 and 4 years old with ventilation tubes inserted for COME and RAOM, respectively.</p>
</sec>
<sec id="S4"><title>Results</title>
<p id="P4">There were no significant between-group differences in either the active measure of ET opening function, dilatory efficiency, or in the passive measures reflecting the magnitude of the forces that tend to hold the ET lumen closed, the opening and closing pressures and passive transET conductance.</p>
</sec>
<sec id="S5"><title>Conclusions</title>
<p id="P5">The results do not support the hypothesis that ET closing forces are less in ears with RAOM when compared to ears with COME and, from the results of earlier studies, ears without disease. Both groups were characterized by a low ET opening efficiency (referenced to ears of adults with no disease history). Because both disease expressions present the same pattern of ET dysfunction, other factors are required to explain why a subset of ears with that type of dysfunction develop RAOM, as opposed to the default expression of COME.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8607378</journal-id>
<journal-id journal-id-type="pubmed-jr-id">5476</journal-id>
<journal-id journal-id-type="nlm-ta">Laryngoscope</journal-id>
<journal-id journal-id-type="iso-abbrev">Laryngoscope</journal-id>
<journal-title-group><journal-title>The Laryngoscope</journal-title>
</journal-title-group>
<issn pub-type="ppub">0023-852X</issn>
<issn pub-type="epub">1531-4995</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">24550093</article-id>
<article-id pub-id-type="pmc">4136992</article-id>
<article-id pub-id-type="doi">10.1002/lary.24647</article-id>
<article-id pub-id-type="manuscript">NIHMS570819</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>The Forced-Response Test Does Not Discriminate Ears with Different Otitis Media Expressions</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Casselbrant</surname>
<given-names>Margaretha L.</given-names>
</name>
<degrees>M.D., Ph.D.</degrees>
</contrib>
<contrib contrib-type="author"><name><surname>Mandel</surname>
<given-names>Ellen M.</given-names>
</name>
<degrees>M.D.</degrees>
</contrib>
<contrib contrib-type="author"><name><surname>Seroky</surname>
<given-names>James T.</given-names>
</name>
<degrees>M.S.</degrees>
</contrib>
<contrib contrib-type="author"><name><surname>Swarts</surname>
<given-names>J. Douglas</given-names>
</name>
<degrees>Ph.D.</degrees>
</contrib>
<contrib contrib-type="author"><name><surname>Doyle</surname>
<given-names>William J.</given-names>
</name>
<degrees>Ph.D.</degrees>
</contrib>
<aff id="A1">Department of Otolaryngology, Division of Pediatric Otolaryngology, Children’s Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA</aff>
</contrib-group>
<author-notes><corresp id="FN1">Corresponding Author: Margaretha L. Casselbrant, M.D., Ph.D., Children’s Hospital of Pittsburgh of UPMC, ENT Department, Faculty Pavilion, 4401 Penn Ave., Pittsburgh, PA 15224, Phone: 412-692-6213, FAX: 412-692-6074, <email>Margaretha.Casselbrant@chp.edu</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>16</day>
<month>4</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="epub"><day>11</day>
<month>8</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="ppub"><month>11</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>01</day>
<month>11</month>
<year>2015</year>
</pub-date>
<volume>124</volume>
<issue>11</issue>
<fpage>2619</fpage>
<lpage>2623</lpage>
<pmc-comment>elocation-id from pubmed: 10.1002/lary.24647</pmc-comment>
<abstract><sec id="S1"><title>Objective</title>
<p id="P1">Test the hypothesis that the Eustachian tube (ET) function measured using standard manometric test methods is different between groups of ears with tympanostomy tubes inserted for recurrent acute otitis media (RAOM) and for chronic otitis media with effusion (COME).</p>
</sec>
<sec id="S2"><title>Study Design</title>
<p id="P2">A cross-sectional study of ET function in populations of young children with different otitis media expressions.</p>
</sec>
<sec id="S3"><title>Methods</title>
<p id="P3">The results for Forced-Response testing of ET function were compared using a general linear model between 37 ears of 26 children and 34 ears of 26 children aged 3 and 4 years old with ventilation tubes inserted for COME and RAOM, respectively.</p>
</sec>
<sec id="S4"><title>Results</title>
<p id="P4">There were no significant between-group differences in either the active measure of ET opening function, dilatory efficiency, or in the passive measures reflecting the magnitude of the forces that tend to hold the ET lumen closed, the opening and closing pressures and passive transET conductance.</p>
</sec>
<sec id="S5"><title>Conclusions</title>
<p id="P5">The results do not support the hypothesis that ET closing forces are less in ears with RAOM when compared to ears with COME and, from the results of earlier studies, ears without disease. Both groups were characterized by a low ET opening efficiency (referenced to ears of adults with no disease history). Because both disease expressions present the same pattern of ET dysfunction, other factors are required to explain why a subset of ears with that type of dysfunction develop RAOM, as opposed to the default expression of COME.</p>
</sec>
</abstract>
<kwd-group><kwd>Eustachian tube</kwd>
<kwd>Function Tests</kwd>
<kwd>Recurrent Acute Otitis Media</kwd>
<kwd>Chronic Otitis Media with Effusion</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
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