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<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Eustachian Tube Opening Measured by Sonotubometry is Poorer in Adults with a History of Past Middle Ear Disease</title>
<author>
<name sortKey="Teixeira, Miriam S" sort="Teixeira, Miriam S" uniqKey="Teixeira M" first="Miriam S." last="Teixeira">Miriam S. Teixeira</name>
</author>
<author>
<name sortKey="Banks, Juliane" sort="Banks, Juliane" uniqKey="Banks J" first="Juliane" last="Banks">Juliane Banks</name>
</author>
<author>
<name sortKey="Swarts, J Douglas" sort="Swarts, J Douglas" uniqKey="Swarts J" first="J. Douglas" last="Swarts">J. Douglas Swarts</name>
</author>
<author>
<name sortKey="Alper, Cuneyt M" sort="Alper, Cuneyt M" uniqKey="Alper C" first="Cuneyt M." last="Alper">Cuneyt M. Alper</name>
</author>
<author>
<name sortKey="Doyle, William J" sort="Doyle, William J" uniqKey="Doyle W" first="William J." last="Doyle">William J. Doyle</name>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PMC</idno>
<idno type="pmid">24491807</idno>
<idno type="pmc">4017584</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017584</idno>
<idno type="RBID">PMC:4017584</idno>
<idno type="doi">10.1016/j.ijporl.2014.01.005</idno>
<date when="2014">2014</date>
<idno type="wicri:Area/Pmc/Corpus">001449</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001449</idno>
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<title xml:lang="en" level="a" type="main">Eustachian Tube Opening Measured by Sonotubometry is Poorer in Adults with a History of Past Middle Ear Disease</title>
<author>
<name sortKey="Teixeira, Miriam S" sort="Teixeira, Miriam S" uniqKey="Teixeira M" first="Miriam S." last="Teixeira">Miriam S. Teixeira</name>
</author>
<author>
<name sortKey="Banks, Juliane" sort="Banks, Juliane" uniqKey="Banks J" first="Juliane" last="Banks">Juliane Banks</name>
</author>
<author>
<name sortKey="Swarts, J Douglas" sort="Swarts, J Douglas" uniqKey="Swarts J" first="J. Douglas" last="Swarts">J. Douglas Swarts</name>
</author>
<author>
<name sortKey="Alper, Cuneyt M" sort="Alper, Cuneyt M" uniqKey="Alper C" first="Cuneyt M." last="Alper">Cuneyt M. Alper</name>
</author>
<author>
<name sortKey="Doyle, William J" sort="Doyle, William J" uniqKey="Doyle W" first="William J." last="Doyle">William J. Doyle</name>
</author>
</analytic>
<series>
<title level="j">International journal of pediatric otorhinolaryngology</title>
<idno type="ISSN">0165-5876</idno>
<idno type="eISSN">1872-8464</idno>
<imprint>
<date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
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<textClass></textClass>
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</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<sec id="S1">
<title>Objective</title>
<p id="P1">Test the hypothesis that active Eustachian tube opening efficiency as measured by sonotubometry is higher in adults with no extant middle-ear disease and no history of previous otitis media (Group-1) when compared to adults with no middle-ear disease but a positive history for otitis media (Group-2).</p>
</sec>
<sec id="S2">
<title>Methods</title>
<p id="P2">Eustachian tube function for 1 ear of 33 otherwise healthy adult subjects, 16 assigned to Group-1 and 17 to Group-2, was tested by sonotubometry using a standard protocol. For each test, the sound envelopes for 3 swallows were abstracted independently by 2 observers from the data stream and 7 descriptive parameters related to sound envelope “shape” were calculated. Interrelatedness among the values for the parameters was explored using correlation analysis. The contributions of swallow, observer and group to the variance in each parameter were evaluated for significance using a General Linear Model.</p>
</sec>
<sec id="S3">
<title>Results</title>
<p id="P3">The shape parameters reflecting envelope height, area and rise and fall rates were highly inter-correlated, but those reflecting envelope widths were not. There was no effect of “swallow” on any of the parameters; but there was a significant “observer” effect on all measures of envelope width, greater for observer-2, and a significant “group” effect for 5 of the 7 shape parameters, all greater in Group-1.</p>
</sec>
<sec id="S4">
<title>Conclusions</title>
<p id="P4">Quantifiable measures of the sound signal “shape” recorded by sonotubometry during swallowing were significantly different between the 2 groups of subjects. This is interpretable as evidencing a more efficient Eustachian tube opening-function in adults with healthy middle ears who do not have a previous history of otitis media when compared to similar adults with a history of prior otitis media. Inefficient Eustachian tube function as children may not be completely resolved by adulthood increasing adult otitis media risk when Eustachian tube function is down-graded by extant upper respiratory diseases that provoke nasopharyngeal inflammation.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-journal-id">8003603</journal-id>
<journal-id journal-id-type="pubmed-jr-id">4311</journal-id>
<journal-id journal-id-type="nlm-ta">Int J Pediatr Otorhinolaryngol</journal-id>
<journal-id journal-id-type="iso-abbrev">Int. J. Pediatr. Otorhinolaryngol.</journal-id>
<journal-title-group>
<journal-title>International journal of pediatric otorhinolaryngology</journal-title>
</journal-title-group>
<issn pub-type="ppub">0165-5876</issn>
<issn pub-type="epub">1872-8464</issn>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">24491807</article-id>
<article-id pub-id-type="pmc">4017584</article-id>
<article-id pub-id-type="doi">10.1016/j.ijporl.2014.01.005</article-id>
<article-id pub-id-type="manuscript">NIHMS564536</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Eustachian Tube Opening Measured by Sonotubometry is Poorer in Adults with a History of Past Middle Ear Disease</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Teixeira</surname>
<given-names>Miriam S.</given-names>
</name>
<degrees>M.D., Ph.D.</degrees>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Banks</surname>
<given-names>Juliane</given-names>
</name>
<degrees>B.S.</degrees>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Swarts</surname>
<given-names>J. Douglas</given-names>
</name>
<degrees>Ph.D.</degrees>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Alper</surname>
<given-names>Cuneyt M.</given-names>
</name>
<degrees>M.D.</degrees>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Doyle</surname>
<given-names>William J.</given-names>
</name>
<degrees>Ph.D.</degrees>
</contrib>
<aff id="A1">Department of Otolaryngology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA</aff>
</contrib-group>
<author-notes>
<corresp id="CR1">
<bold>Address Correspondence to:</bold>
Miriam S. Teixeira, M.D., Ph.D. 3420 5th Ave Oakland Medical Bldg, Room 118 Pittsburgh PA, 15213 USA Phone: +1 412 692-3594 FAX: +1 412 692-7555
<email>teixeirams@upmc.edu</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted">
<day>28</day>
<month>3</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="epub">
<day>13</day>
<month>1</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="ppub">
<month>4</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="pmc-release">
<day>01</day>
<month>4</month>
<year>2015</year>
</pub-date>
<volume>78</volume>
<issue>4</issue>
<fpage>593</fpage>
<lpage>598</lpage>
<pmc-comment>elocation-id from pubmed: 10.1016/j.ijporl.2014.01.005</pmc-comment>
<permissions>
<copyright-statement>© 2014 Elsevier Ireland Ltd. All rights reserved.</copyright-statement>
<copyright-year>2014</copyright-year>
</permissions>
<abstract>
<sec id="S1">
<title>Objective</title>
<p id="P1">Test the hypothesis that active Eustachian tube opening efficiency as measured by sonotubometry is higher in adults with no extant middle-ear disease and no history of previous otitis media (Group-1) when compared to adults with no middle-ear disease but a positive history for otitis media (Group-2).</p>
</sec>
<sec id="S2">
<title>Methods</title>
<p id="P2">Eustachian tube function for 1 ear of 33 otherwise healthy adult subjects, 16 assigned to Group-1 and 17 to Group-2, was tested by sonotubometry using a standard protocol. For each test, the sound envelopes for 3 swallows were abstracted independently by 2 observers from the data stream and 7 descriptive parameters related to sound envelope “shape” were calculated. Interrelatedness among the values for the parameters was explored using correlation analysis. The contributions of swallow, observer and group to the variance in each parameter were evaluated for significance using a General Linear Model.</p>
</sec>
<sec id="S3">
<title>Results</title>
<p id="P3">The shape parameters reflecting envelope height, area and rise and fall rates were highly inter-correlated, but those reflecting envelope widths were not. There was no effect of “swallow” on any of the parameters; but there was a significant “observer” effect on all measures of envelope width, greater for observer-2, and a significant “group” effect for 5 of the 7 shape parameters, all greater in Group-1.</p>
</sec>
<sec id="S4">
<title>Conclusions</title>
<p id="P4">Quantifiable measures of the sound signal “shape” recorded by sonotubometry during swallowing were significantly different between the 2 groups of subjects. This is interpretable as evidencing a more efficient Eustachian tube opening-function in adults with healthy middle ears who do not have a previous history of otitis media when compared to similar adults with a history of prior otitis media. Inefficient Eustachian tube function as children may not be completely resolved by adulthood increasing adult otitis media risk when Eustachian tube function is down-graded by extant upper respiratory diseases that provoke nasopharyngeal inflammation.</p>
</sec>
</abstract>
<kwd-group>
<kwd>Otitis media</kwd>
<kwd>Eustachian tube</kwd>
<kwd>adults</kwd>
<kwd>sonotubometry</kwd>
<kwd>methodology</kwd>
<kwd>otitis media risk</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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