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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Are Estimates of Meaningful Decline in Mobility Performance Consistent Among Clinically Important Subgroups? (Health ABC Study)</title><author><name sortKey="Perera, Subashan" sort="Perera, Subashan" uniqKey="Perera S" first="Subashan" last="Perera">Subashan Perera</name><affiliation><nlm:aff wicri:cut=" and" id="AF0001"><institution>Division of Geriatric Medicine</institution></nlm:aff></affiliation></author><author><name sortKey="Studenski, Stephanie" sort="Studenski, Stephanie" uniqKey="Studenski S" first="Stephanie" last="Studenski">Stephanie Studenski</name><affiliation><nlm:aff wicri:cut=" and" id="AF0001"><institution>Division of Geriatric Medicine</institution></nlm:aff></affiliation></author><author><name sortKey="Newman, Anne" sort="Newman, Anne" uniqKey="Newman A" first="Anne" last="Newman">Anne Newman</name><affiliation><nlm:aff id="AF0002"><institution>Department of Epidemiology, University of Pittsburgh</institution>,<addr-line>Pennsylvania</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Simonsick, Eleanor" sort="Simonsick, Eleanor" uniqKey="Simonsick E" first="Eleanor" last="Simonsick">Eleanor Simonsick</name><affiliation><nlm:aff id="AF0003"><institution>Intramural Research Program, National Institute on Aging</institution>,<addr-line>Bethesda, Maryland</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Harris, Tamara" sort="Harris, Tamara" uniqKey="Harris T" first="Tamara" last="Harris">Tamara Harris</name><affiliation><nlm:aff id="AF0003"><institution>Intramural Research Program, National Institute on Aging</institution>,<addr-line>Bethesda, Maryland</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Schwartz, Ann" sort="Schwartz, Ann" uniqKey="Schwartz A" first="Ann" last="Schwartz">Ann Schwartz</name><affiliation><nlm:aff id="AF0004"><institution>Department of Epidemiology, University of California-San Francisco</institution>.</nlm:aff></affiliation></author><author><name sortKey="Visser, Marjolein" sort="Visser, Marjolein" uniqKey="Visser M" first="Marjolein" last="Visser">Marjolein Visser</name><affiliation><nlm:aff id="AF0005"><institution>Department of Epidemiology and Biostatistics, Vrije Universiteit</institution>,<addr-line>Amsterdam</addr-line>,<country>The Netherlands</country>.</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24615070</idno><idno type="pmc">4172035</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172035</idno><idno type="RBID">PMC:4172035</idno><idno type="doi">10.1093/gerona/glu033</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000A76</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000A76</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Are Estimates of Meaningful Decline in Mobility Performance Consistent Among Clinically Important Subgroups? (Health ABC Study)</title><author><name sortKey="Perera, Subashan" sort="Perera, Subashan" uniqKey="Perera S" first="Subashan" last="Perera">Subashan Perera</name><affiliation><nlm:aff wicri:cut=" and" id="AF0001"><institution>Division of Geriatric Medicine</institution></nlm:aff></affiliation></author><author><name sortKey="Studenski, Stephanie" sort="Studenski, Stephanie" uniqKey="Studenski S" first="Stephanie" last="Studenski">Stephanie Studenski</name><affiliation><nlm:aff wicri:cut=" and" id="AF0001"><institution>Division of Geriatric Medicine</institution></nlm:aff></affiliation></author><author><name sortKey="Newman, Anne" sort="Newman, Anne" uniqKey="Newman A" first="Anne" last="Newman">Anne Newman</name><affiliation><nlm:aff id="AF0002"><institution>Department of Epidemiology, University of Pittsburgh</institution>,<addr-line>Pennsylvania</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Simonsick, Eleanor" sort="Simonsick, Eleanor" uniqKey="Simonsick E" first="Eleanor" last="Simonsick">Eleanor Simonsick</name><affiliation><nlm:aff id="AF0003"><institution>Intramural Research Program, National Institute on Aging</institution>,<addr-line>Bethesda, Maryland</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Harris, Tamara" sort="Harris, Tamara" uniqKey="Harris T" first="Tamara" last="Harris">Tamara Harris</name><affiliation><nlm:aff id="AF0003"><institution>Intramural Research Program, National Institute on Aging</institution>,<addr-line>Bethesda, Maryland</addr-line>.</nlm:aff></affiliation></author><author><name sortKey="Schwartz, Ann" sort="Schwartz, Ann" uniqKey="Schwartz A" first="Ann" last="Schwartz">Ann Schwartz</name><affiliation><nlm:aff id="AF0004"><institution>Department of Epidemiology, University of California-San Francisco</institution>.</nlm:aff></affiliation></author><author><name sortKey="Visser, Marjolein" sort="Visser, Marjolein" uniqKey="Visser M" first="Marjolein" last="Visser">Marjolein Visser</name><affiliation><nlm:aff id="AF0005"><institution>Department of Epidemiology and Biostatistics, Vrije Universiteit</institution>,<addr-line>Amsterdam</addr-line>,<country>The Netherlands</country>.</nlm:aff></affiliation></author></analytic><series><title level="j">The Journals of Gerontology Series A: Biological Sciences and Medical Sciences</title><idno type="ISSN">1079-5006</idno><idno type="eISSN">1758-535X</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background.</title><p>Meaningful change criteria help determine if function has improved or declined, but their magnitudes may vary across clinically relevant subgroups. We estimate meaningful decline in four common measures of physical performance in subgroups of older adults based on initial performance, demographics, chronic conditions, and health status.</p></sec><sec><title>Methods.</title><p>We used baseline (Year 1) and Year 4 data from the Health, Aging and Body Composition (Health ABC) study, a well-functioning cohort at baseline of white and black men and women (age 70–79), to evaluate the magnitude of meaningful decline in performance (6 m gait speed, 400-m walk time (400MWT), Short Physical Performance Battery, and Health ABC Physical Performance Battery (PPB), based on self-reported perceived mobility anchors (climbing 10 steps and walking ¼ mile). Estimates were stratified by initial performance, demographics, health status, chronic conditions, and body mass index, and compared across strata.</p></sec><sec><title>Results.</title><p>For all four measures, small and substantial decline estimates were generally consistent among subgroups based on initial performance, demographics, health status, and chronic conditions. The only exception was for 400MWT, where men had greater estimates than women. For PPB, small change was 0.12 points, and substantial change was 0.22 points.</p></sec><sec><title>Conclusions.</title><p>Estimates of small and substantial meaningful decline resemble those previously reported for gait speed, 400MWT, and SPPB. Magnitudes of meaningful performance decline appear to be generally consistent across strata of initial performance, demographics, health status, body mass index, and chronic conditions.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Gerontol A Biol Sci Med Sci</journal-id><journal-id journal-id-type="iso-abbrev">J. Gerontol. A Biol. Sci. Med. Sci</journal-id><journal-id journal-id-type="hwp">gerona</journal-id><journal-id journal-id-type="publisher-id">gerona</journal-id><journal-title-group><journal-title>The Journals of Gerontology Series A: Biological Sciences and Medical Sciences</journal-title></journal-title-group><issn pub-type="ppub">1079-5006</issn><issn pub-type="epub">1758-535X</issn><publisher><publisher-name>Oxford University Press</publisher-name><publisher-loc>US</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">24615070</article-id><article-id pub-id-type="pmc">4172035</article-id><article-id pub-id-type="doi">10.1093/gerona/glu033</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Are Estimates of Meaningful Decline in Mobility Performance Consistent Among Clinically Important Subgroups? (Health ABC Study)</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Perera</surname><given-names>Subashan</given-names></name><xref ref-type="aff" rid="AF0001"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Studenski</surname><given-names>Stephanie</given-names></name><xref ref-type="aff" rid="AF0001"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Newman</surname><given-names>Anne</given-names></name><xref ref-type="aff" rid="AF0002"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Simonsick</surname><given-names>Eleanor</given-names></name><xref ref-type="aff" rid="AF0003"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Harris</surname><given-names>Tamara</given-names></name><xref ref-type="aff" rid="AF0003"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Schwartz</surname><given-names>Ann</given-names></name><xref ref-type="aff" rid="AF0004"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Visser</surname><given-names>Marjolein</given-names></name><xref ref-type="aff" rid="AF0005"><sup>5</sup></xref></contrib><contrib contrib-type="author"><collab>for the Health ABC Study</collab></contrib><aff id="AF0001"><sup>1</sup><institution>Division of Geriatric Medicine</institution> and</aff><aff id="AF0002"><sup>2</sup><institution>Department of Epidemiology, University of Pittsburgh</institution>,<addr-line>Pennsylvania</addr-line>.</aff><aff id="AF0003"><sup>3</sup><institution>Intramural Research Program, National Institute on Aging</institution>,<addr-line>Bethesda, Maryland</addr-line>.</aff><aff id="AF0004"><sup>4</sup><institution>Department of Epidemiology, University of California-San Francisco</institution>.</aff><aff id="AF0005"><sup>5</sup><institution>Department of Epidemiology and Biostatistics, Vrije Universiteit</institution>,<addr-line>Amsterdam</addr-line>,<country>The Netherlands</country>.</aff></contrib-group><author-notes><corresp id="c1">Address correspondence to Subashan Perera, PhD, Division of Geriatric Medicine, University of Pittsburgh, 3471 Fifth Avenue, Suite 500, Pittsburgh PA 15213. Email: <email>ksp9@pitt.edu</email></corresp><fn fn-type="other"><p><italic>Decision Editor: James Goodwin, MD</italic></p></fn></author-notes><pub-date pub-type="ppub"><month>10</month><year>2014</year></pub-date><pub-date pub-type="epub"><day>10</day><month>3</month><year>2014</year></pub-date><volume>69</volume><issue>10</issue><fpage>1260</fpage><lpage>1268</lpage><history><date date-type="received"><day>23</day><month>7</month><year>2013</year></date><date date-type="accepted"><day>7</day><month>2</month><year>2014</year></date></history><permissions><copyright-statement>© The Author 2014. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</copyright-statement><copyright-year>2014</copyright-year></permissions><abstract><sec><title>Background.</title><p>Meaningful change criteria help determine if function has improved or declined, but their magnitudes may vary across clinically relevant subgroups. We estimate meaningful decline in four common measures of physical performance in subgroups of older adults based on initial performance, demographics, chronic conditions, and health status.</p></sec><sec><title>Methods.</title><p>We used baseline (Year 1) and Year 4 data from the Health, Aging and Body Composition (Health ABC) study, a well-functioning cohort at baseline of white and black men and women (age 70–79), to evaluate the magnitude of meaningful decline in performance (6 m gait speed, 400-m walk time (400MWT), Short Physical Performance Battery, and Health ABC Physical Performance Battery (PPB), based on self-reported perceived mobility anchors (climbing 10 steps and walking ¼ mile). Estimates were stratified by initial performance, demographics, health status, chronic conditions, and body mass index, and compared across strata.</p></sec><sec><title>Results.</title><p>For all four measures, small and substantial decline estimates were generally consistent among subgroups based on initial performance, demographics, health status, and chronic conditions. The only exception was for 400MWT, where men had greater estimates than women. For PPB, small change was 0.12 points, and substantial change was 0.22 points.</p></sec><sec><title>Conclusions.</title><p>Estimates of small and substantial meaningful decline resemble those previously reported for gait speed, 400MWT, and SPPB. Magnitudes of meaningful performance decline appear to be generally consistent across strata of initial performance, demographics, health status, body mass index, and chronic conditions.</p></sec></abstract><kwd-group><title>Key Words:</title><kwd>Balance</kwd><kwd>Epidemiology</kwd><kwd>Functional performance</kwd><kwd>Gait.</kwd></kwd-group><counts><page-count count="9"></page-count></counts></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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