PittsburghV1, Ncbi, Merge, bibRecord, 003816

Leptin, Adiponectin, and Heart Rate Variability Among Police Officers

Identifieur interne : 003816 ( Ncbi/Merge ); précédent : 003815; suivant : 003817

Leptin, Adiponectin, and Heart Rate Variability Among Police Officers

Auteurs : Luenda E. Charles [États-Unis] ; Cecil M. Burchfiel [États-Unis] ; Khachatur Sarkisian [États-Unis] ; Shengqiao Li [États-Unis] ; Diane B. Miller [États-Unis] ; Ja K. Gu [États-Unis] ; Desta Fekedulegn [États-Unis] ; John M. Violanti [États-Unis] ; Michael E. Andrew [États-Unis]

Source :

American journal of human biology : the official journal of the Human Biology Council [ 1042-0533 ] ; 2014.

RBID : PMC:4699294

Abstract

Objectives

Police officers have a high prevalence of cardiovascular disease (CVD). Reduced heart rate variability (HRV) is known to increase CVD risk. Leptin and adiponectin may be related to CVD health. Therefore, our objective was to investigate the relationship between these variables and HRV.

Methods

Leptin and adiponectin levels were measured in 388 officers from the Buffalo Cardio-Metabolic Occupational Police Stress study. HRV was assessed according to methods published by the Task Force of the European Society of Cardiology and the North American Society of Pacing Electrophysiology for measurement and analysis of HRV. Mean values of high-frequency (HF) and low-frequency (LF) HRV were compared across tertiles of leptin and adiponectin using analysis of variance and analysis of covariance; trends were assessed using linear regression models.

Results

Leptin, but not adiponectin, was significantly and inversely associated with HRV. Body mass index (BMI) and percent body fat significantly modified the association between leptin and LF (but not HF) HRV. Among officers with BMI < 25 kg/m², leptin was not significantly associated with HRV. However, among officers with BMI ≥ 25 kg/m², leptin was inversely associated with HRV, after adjustment for age, gender, and race/ethnicity; HF HRV, P = 0.019 and LF HRV, P < 0.0001. Similarly, among officers with percent body fat ≥ 25.5%, leptin and LF HRV showed significant, inverse associations (adjusted P = 0.001).

Conclusions

Leptin levels were inversely associated with LF HRV, especially among officers with increased adiposity. Increased leptin levels may be associated with CVD-related health problems.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699294

DOI: 10.1002/ajhb.22636
PubMed: 25270126
PubMed Central: 4699294

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Le document en format XML

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<author><name sortKey="Gu, Ja K" sort="Gu, Ja K" uniqKey="Gu J" first="Ja K." last="Gu">Ja K. Gu</name>
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<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">État de New York</region>
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<author><name sortKey="Andrew, Michael E" sort="Andrew, Michael E" uniqKey="Andrew M" first="Michael E." last="Andrew">Michael E. Andrew</name>
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<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objectives</title>
<p id="P1">Police officers have a high prevalence of cardiovascular disease (CVD). Reduced heart rate variability (HRV) is known to increase CVD risk. Leptin and adiponectin may be related to CVD health. Therefore, our objective was to investigate the relationship between these variables and HRV.</p>
</sec>
<sec id="S2"><title>Methods</title>
<p id="P2">Leptin and adiponectin levels were measured in 388 officers from the Buffalo Cardio-Metabolic Occupational Police Stress study. HRV was assessed according to methods published by the Task Force of the European Society of Cardiology and the North American Society of Pacing Electrophysiology for measurement and analysis of HRV. Mean values of high-frequency (HF) and low-frequency (LF) HRV were compared across tertiles of leptin and adiponectin using analysis of variance and analysis of covariance; trends were assessed using linear regression models.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">Leptin, but not adiponectin, was significantly and inversely associated with HRV. Body mass index (BMI) and percent body fat significantly modified the association between leptin and LF (but not HF) HRV. Among officers with BMI < 25 kg/m<sup>2</sup>
, leptin was not significantly associated with HRV. However, among officers with BMI ≥ 25 kg/m<sup>2</sup>
, leptin was inversely associated with HRV, after adjustment for age, gender, and race/ethnicity; HF HRV, <italic>P</italic>
 = 0.019 and LF HRV, <italic>P</italic>
 < 0.0001. Similarly, among officers with percent body fat ≥ 25.5%, leptin and LF HRV showed significant, inverse associations (adjusted <italic>P</italic>
 = 0.001).</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">Leptin levels were inversely associated with LF HRV, especially among officers with increased adiposity. Increased leptin levels may be associated with CVD-related health problems.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
  <pmc-dir>properties manuscript</pmc-dir>
  <front><journal-meta><journal-id journal-id-type="nlm-journal-id">8915029</journal-id>
<journal-id journal-id-type="pubmed-jr-id">22403</journal-id>
<journal-id journal-id-type="nlm-ta">Am J Hum Biol</journal-id>
<journal-id journal-id-type="iso-abbrev">Am. J. Hum. Biol.</journal-id>
<journal-title-group><journal-title>American journal of human biology : the official journal of the Human Biology Council</journal-title>
</journal-title-group>
<issn pub-type="ppub">1042-0533</issn>
<issn pub-type="epub">1520-6300</issn>
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<article-id pub-id-type="pmc">4699294</article-id>
<article-id pub-id-type="doi">10.1002/ajhb.22636</article-id>
<article-id pub-id-type="manuscript">HHSPA746852</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Leptin, Adiponectin, and Heart Rate Variability Among Police Officers</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>CHARLES</surname>
<given-names>LUENDA E.</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
<xref ref-type="corresp" rid="CR1">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>BURCHFIEL</surname>
<given-names>CECIL M.</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>SARKISIAN</surname>
<given-names>KHACHATUR</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>LI</surname>
<given-names>SHENGQIAO</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>MILLER</surname>
<given-names>DIANE B.</given-names>
</name>
<xref ref-type="aff" rid="A3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>GU</surname>
<given-names>JA K.</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>FEKEDULEGN</surname>
<given-names>DESTA</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>VIOLANTI</surname>
<given-names>JOHN M.</given-names>
</name>
<xref ref-type="aff" rid="A4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>ANDREW</surname>
<given-names>MICHAEL E.</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
</contrib-group>
<aff id="A1"><label>1</label>
Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia</aff>
<aff id="A2"><label>2</label>
University of Pittsburgh Medical Center Health Plan, Pittsburgh, Pennsylvania</aff>
<aff id="A3"><label>3</label>
Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia</aff>
<aff id="A4"><label>4</label>
Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, State University of New York at Buffalo, Buffalo, New York</aff>
<author-notes><corresp id="CR1"><label>*</label>
Correspondence to: Luenda E. Charles, Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, MS L-4050, 1095 Willowdale Rd., Morgantown, WV 26505-2888, USA. <email>lcharles@cdc.gov</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>23</day>
<month>12</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="epub"><day>01</day>
<month>10</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="ppub"><season>Mar-Apr</season>
<year>2015</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>04</day>
<month>1</month>
<year>2016</year>
</pub-date>
<volume>27</volume>
<issue>2</issue>
<fpage>184</fpage>
<lpage>191</lpage>
<pmc-comment>elocation-id from pubmed: 10.1002/ajhb.22636</pmc-comment>
      <abstract><sec id="S1"><title>Objectives</title>
<p id="P1">Police officers have a high prevalence of cardiovascular disease (CVD). Reduced heart rate variability (HRV) is known to increase CVD risk. Leptin and adiponectin may be related to CVD health. Therefore, our objective was to investigate the relationship between these variables and HRV.</p>
</sec>
<sec id="S2"><title>Methods</title>
<p id="P2">Leptin and adiponectin levels were measured in 388 officers from the Buffalo Cardio-Metabolic Occupational Police Stress study. HRV was assessed according to methods published by the Task Force of the European Society of Cardiology and the North American Society of Pacing Electrophysiology for measurement and analysis of HRV. Mean values of high-frequency (HF) and low-frequency (LF) HRV were compared across tertiles of leptin and adiponectin using analysis of variance and analysis of covariance; trends were assessed using linear regression models.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">Leptin, but not adiponectin, was significantly and inversely associated with HRV. Body mass index (BMI) and percent body fat significantly modified the association between leptin and LF (but not HF) HRV. Among officers with BMI < 25 kg/m<sup>2</sup>
, leptin was not significantly associated with HRV. However, among officers with BMI ≥ 25 kg/m<sup>2</sup>
, leptin was inversely associated with HRV, after adjustment for age, gender, and race/ethnicity; HF HRV, <italic>P</italic>
 = 0.019 and LF HRV, <italic>P</italic>
 < 0.0001. Similarly, among officers with percent body fat ≥ 25.5%, leptin and LF HRV showed significant, inverse associations (adjusted <italic>P</italic>
 = 0.001).</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">Leptin levels were inversely associated with LF HRV, especially among officers with increased adiposity. Increased leptin levels may be associated with CVD-related health problems.</p>
</sec>
</abstract>
</article-meta>
</front>
</pmc>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Pennsylvanie</li>
<li>Virginie-Occidentale</li>
<li>État de New York</li>
</region>
</list>
<tree><country name="États-Unis"><region name="Virginie-Occidentale"><name sortKey="Charles, Luenda E" sort="Charles, Luenda E" uniqKey="Charles L" first="Luenda E." last="Charles">Luenda E. Charles</name>
</region>
<name sortKey="Andrew, Michael E" sort="Andrew, Michael E" uniqKey="Andrew M" first="Michael E." last="Andrew">Michael E. Andrew</name>
<name sortKey="Burchfiel, Cecil M" sort="Burchfiel, Cecil M" uniqKey="Burchfiel C" first="Cecil M." last="Burchfiel">Cecil M. Burchfiel</name>
<name sortKey="Fekedulegn, Desta" sort="Fekedulegn, Desta" uniqKey="Fekedulegn D" first="Desta" last="Fekedulegn">Desta Fekedulegn</name>
<name sortKey="Gu, Ja K" sort="Gu, Ja K" uniqKey="Gu J" first="Ja K." last="Gu">Ja K. Gu</name>
<name sortKey="Li, Shengqiao" sort="Li, Shengqiao" uniqKey="Li S" first="Shengqiao" last="Li">Shengqiao Li</name>
<name sortKey="Miller, Diane B" sort="Miller, Diane B" uniqKey="Miller D" first="Diane B." last="Miller">Diane B. Miller</name>
<name sortKey="Sarkisian, Khachatur" sort="Sarkisian, Khachatur" uniqKey="Sarkisian K" first="Khachatur" last="Sarkisian">Khachatur Sarkisian</name>
<name sortKey="Violanti, John M" sort="Violanti, John M" uniqKey="Violanti J" first="John M." last="Violanti">John M. Violanti</name>
</country>
</tree>
</affiliations>
</record>

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   |wiki=    Wicri/Amérique
   |area=    PittsburghV1
   |flux=    Ncbi
   |étape=   Merge
   |type=    RBID
   |clé=     PMC:4699294
   |texte=   Leptin, Adiponectin, and Heart Rate Variability Among Police Officers
}}

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	Serveur d'exploration sur Pittsburgh
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Serveur d'exploration sur Pittsburgh

Leptin, Adiponectin, and Heart Rate Variability Among Police Officers

Leptin, Adiponectin, and Heart Rate Variability Among Police Officers

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Abstract

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