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Comparison of tolerance and cost-effectiveness of two nasal anesthesia techniques for transnasal flexible laryngoscopy.

Identifieur interne : 000F70 ( Ncbi/Merge ); précédent : 000F69; suivant : 000F71

Comparison of tolerance and cost-effectiveness of two nasal anesthesia techniques for transnasal flexible laryngoscopy.

Auteurs : Vyvy N. Young [États-Unis] ; Libby J. Smith ; Clark A. Rosen

Source :

RBID : pubmed:24496740

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English descriptors

Abstract

(1) Compare tolerance of aerosolized spray versus syringe administration of topical anesthesia for transnasal flexible laryngoscopy (TFL), (2) analyze cost-effectiveness of both techniques.

DOI: 10.1177/0194599813519952
PubMed: 24496740

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pubmed:24496740

Le document en format XML

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<title xml:lang="en">Comparison of tolerance and cost-effectiveness of two nasal anesthesia techniques for transnasal flexible laryngoscopy.</title>
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<name sortKey="Young, Vyvy N" sort="Young, Vyvy N" uniqKey="Young V" first="Vyvy N" last="Young">Vyvy N. Young</name>
<affiliation wicri:level="2">
<nlm:affiliation>University of Pittsburgh Voice Center Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>University of Pittsburgh Voice Center Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania</wicri:regionArea>
<placeName>
<region type="state">Pennsylvanie</region>
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<author>
<name sortKey="Smith, Libby J" sort="Smith, Libby J" uniqKey="Smith L" first="Libby J" last="Smith">Libby J. Smith</name>
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<author>
<name sortKey="Rosen, Clark A" sort="Rosen, Clark A" uniqKey="Rosen C" first="Clark A" last="Rosen">Clark A. Rosen</name>
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<name sortKey="Young, Vyvy N" sort="Young, Vyvy N" uniqKey="Young V" first="Vyvy N" last="Young">Vyvy N. Young</name>
<affiliation wicri:level="2">
<nlm:affiliation>University of Pittsburgh Voice Center Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>University of Pittsburgh Voice Center Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania</wicri:regionArea>
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<region type="state">Pennsylvanie</region>
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<author>
<name sortKey="Smith, Libby J" sort="Smith, Libby J" uniqKey="Smith L" first="Libby J" last="Smith">Libby J. Smith</name>
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<name sortKey="Rosen, Clark A" sort="Rosen, Clark A" uniqKey="Rosen C" first="Clark A" last="Rosen">Clark A. Rosen</name>
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<series>
<title level="j">Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery</title>
<idno type="eISSN">1097-6817</idno>
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<date when="2014" type="published">2014</date>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Administration, Intranasal</term>
<term>Adult</term>
<term>Aged</term>
<term>Anesthesia, Local (economics)</term>
<term>Anesthesia, Local (methods)</term>
<term>Anesthetics, Local (administration & dosage)</term>
<term>Anesthetics, Local (economics)</term>
<term>Cost-Benefit Analysis</term>
<term>Female</term>
<term>Fiber Optic Technology</term>
<term>Humans</term>
<term>Injections, Intralesional (economics)</term>
<term>Laryngoscopes</term>
<term>Laryngoscopy (instrumentation)</term>
<term>Laryngoscopy (methods)</term>
<term>Lidocaine (administration & dosage)</term>
<term>Lidocaine (economics)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Nasal Cavity (drug effects)</term>
<term>Nasal Sprays</term>
<term>Pain Measurement (drug effects)</term>
<term>Patient Satisfaction</term>
<term>Prospective Studies</term>
<term>Single-Blind Method</term>
<term>Syringes (economics)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Administration par voie nasale</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Analyse coût-bénéfice</term>
<term>Anesthésie locale ()</term>
<term>Anesthésie locale (économie)</term>
<term>Anesthésiques locaux (administration et posologie)</term>
<term>Anesthésiques locaux (économie)</term>
<term>Femelle</term>
<term>Fosse nasale ()</term>
<term>Humains</term>
<term>Injections intralésionnelles (économie)</term>
<term>Laryngoscopes</term>
<term>Laryngoscopie ()</term>
<term>Laryngoscopie (instrumentation)</term>
<term>Lidocaïne (administration et posologie)</term>
<term>Lidocaïne (économie)</term>
<term>Mesure de la douleur ()</term>
<term>Mâle</term>
<term>Méthode en simple aveugle</term>
<term>Pulvérisations nasales</term>
<term>Satisfaction du patient</term>
<term>Seringues (économie)</term>
<term>Sujet âgé</term>
<term>Technologie des fibres optiques</term>
<term>Études prospectives</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en">
<term>Anesthetics, Local</term>
<term>Lidocaine</term>
</keywords>
<keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr">
<term>Anesthésiques locaux</term>
<term>Lidocaïne</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en">
<term>Nasal Cavity</term>
<term>Pain Measurement</term>
</keywords>
<keywords scheme="MESH" qualifier="economics" xml:lang="en">
<term>Anesthesia, Local</term>
<term>Anesthetics, Local</term>
<term>Injections, Intralesional</term>
<term>Lidocaine</term>
<term>Syringes</term>
</keywords>
<keywords scheme="MESH" qualifier="instrumentation" xml:lang="en">
<term>Laryngoscopy</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Anesthesia, Local</term>
<term>Laryngoscopy</term>
</keywords>
<keywords scheme="MESH" qualifier="économie" xml:lang="fr">
<term>Anesthésie locale</term>
<term>Anesthésiques locaux</term>
<term>Injections intralésionnelles</term>
<term>Laryngoscopie</term>
<term>Lidocaïne</term>
<term>Seringues</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Administration, Intranasal</term>
<term>Adult</term>
<term>Aged</term>
<term>Cost-Benefit Analysis</term>
<term>Female</term>
<term>Fiber Optic Technology</term>
<term>Humans</term>
<term>Laryngoscopes</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Nasal Sprays</term>
<term>Patient Satisfaction</term>
<term>Prospective Studies</term>
<term>Single-Blind Method</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Administration par voie nasale</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Analyse coût-bénéfice</term>
<term>Anesthésie locale</term>
<term>Femelle</term>
<term>Fosse nasale</term>
<term>Humains</term>
<term>Laryngoscopes</term>
<term>Laryngoscopie</term>
<term>Mesure de la douleur</term>
<term>Mâle</term>
<term>Méthode en simple aveugle</term>
<term>Pulvérisations nasales</term>
<term>Satisfaction du patient</term>
<term>Sujet âgé</term>
<term>Technologie des fibres optiques</term>
<term>Études prospectives</term>
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<front>
<div type="abstract" xml:lang="en">(1) Compare tolerance of aerosolized spray versus syringe administration of topical anesthesia for transnasal flexible laryngoscopy (TFL), (2) analyze cost-effectiveness of both techniques.</div>
</front>
</TEI>
<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">24496740</PMID>
<DateCreated>
<Year>2014</Year>
<Month>04</Month>
<Day>02</Day>
</DateCreated>
<DateCompleted>
<Year>2014</Year>
<Month>05</Month>
<Day>29</Day>
</DateCompleted>
<DateRevised>
<Year>2014</Year>
<Month>04</Month>
<Day>02</Day>
</DateRevised>
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<Journal>
<ISSN IssnType="Electronic">1097-6817</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>150</Volume>
<Issue>4</Issue>
<PubDate>
<Year>2014</Year>
<Month>Apr</Month>
</PubDate>
</JournalIssue>
<Title>Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery</Title>
<ISOAbbreviation>Otolaryngol Head Neck Surg</ISOAbbreviation>
</Journal>
<ArticleTitle>Comparison of tolerance and cost-effectiveness of two nasal anesthesia techniques for transnasal flexible laryngoscopy.</ArticleTitle>
<Pagination>
<MedlinePgn>582-6</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1177/0194599813519952</ELocationID>
<Abstract>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">(1) Compare tolerance of aerosolized spray versus syringe administration of topical anesthesia for transnasal flexible laryngoscopy (TFL), (2) analyze cost-effectiveness of both techniques.</AbstractText>
<AbstractText Label="STUDY DESIGN" NlmCategory="METHODS">Prospective, blinded, randomized trial.</AbstractText>
<AbstractText Label="SETTING" NlmCategory="METHODS">Tertiary academic laryngology practice.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">One hundred and eight patients underwent TFL over 3 months. Patients were randomized to receive equivalent dose 1:1 neosynephrine/4% plain lidocaine mixture via aerosolized spray ("spray") or application with 1-cc syringe ("syringe"). Patients and physicians independently rated comfort of TFL on 5-point scale (1 = not at all comfortable to 5 = very comfortable). Data were collected on patient and endoscopist experience with TFL and reasons for poor tolerance of laryngoscopy. Cost analyses of disposable spray tips and syringes were calculated.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Both patients and physicians reported very high tolerance of TFL. Patient tolerance appears to be similar between spray- versus syringe-administered anesthesia, although study limitations preclude definitive analysis. Poor tolerance of laryngoscopy was reported in 6.5% with comparable distribution between anesthetic delivery methods. There was no impact of patient prior experience with TFL, and there was no difference between anesthetic methods for TFL performed by resident, fellow, or attending. The difference between costs of the disposable spray tip versus syringe was $1.32 per unit.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Use of a 1-cc syringe is an effective method to provide topical nasal anesthesia for TFL and saves $1.32 per unit compared to disposable spray tips. In our practice, transition to syringe-administered nasal anesthesia is projected to save $1300 per 1000 patients, or an anticipated $1000 per year per physician, with excellent patient tolerance of TFL.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Young</LastName>
<ForeName>VyVy N</ForeName>
<Initials>VN</Initials>
<AffiliationInfo>
<Affiliation>University of Pittsburgh Voice Center Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Smith</LastName>
<ForeName>Libby J</ForeName>
<Initials>LJ</Initials>
</Author>
<Author ValidYN="Y">
<LastName>Rosen</LastName>
<ForeName>Clark A</ForeName>
<Initials>CA</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList>
<PublicationType UI="D003160">Comparative Study</PublicationType>
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<Year>2014</Year>
<Month>02</Month>
<Day>04</Day>
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<Country>England</Country>
<MedlineTA>Otolaryngol Head Neck Surg</MedlineTA>
<NlmUniqueID>8508176</NlmUniqueID>
<ISSNLinking>0194-5998</ISSNLinking>
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<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000779">Anesthetics, Local</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D059085">Nasal Sprays</NameOfSubstance>
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<RegistryNumber>98PI200987</RegistryNumber>
<NameOfSubstance UI="D008012">Lidocaine</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList>
<MeshHeading>
<DescriptorName UI="D000281" MajorTopicYN="N">Administration, Intranasal</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000772" MajorTopicYN="N">Anesthesia, Local</DescriptorName>
<QualifierName UI="Q000191" MajorTopicYN="Y">economics</QualifierName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
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<MeshHeading>
<DescriptorName UI="D000779" MajorTopicYN="N">Anesthetics, Local</DescriptorName>
<QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName>
<QualifierName UI="Q000191" MajorTopicYN="N">economics</QualifierName>
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<MeshHeading>
<DescriptorName UI="D003362" MajorTopicYN="N">Cost-Benefit Analysis</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005336" MajorTopicYN="N">Fiber Optic Technology</DescriptorName>
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<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<DescriptorName UI="D015552" MajorTopicYN="N">Injections, Intralesional</DescriptorName>
<QualifierName UI="Q000191" MajorTopicYN="N">economics</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D020704" MajorTopicYN="N">Laryngoscopes</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D007828" MajorTopicYN="N">Laryngoscopy</DescriptorName>
<QualifierName UI="Q000295" MajorTopicYN="N">instrumentation</QualifierName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008012" MajorTopicYN="N">Lidocaine</DescriptorName>
<QualifierName UI="Q000008" MajorTopicYN="Y">administration & dosage</QualifierName>
<QualifierName UI="Q000191" MajorTopicYN="N">economics</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
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<DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
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<DescriptorName UI="D009296" MajorTopicYN="N">Nasal Cavity</DescriptorName>
<QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D059085" MajorTopicYN="Y">Nasal Sprays</DescriptorName>
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<DescriptorName UI="D010147" MajorTopicYN="N">Pain Measurement</DescriptorName>
<QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName>
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<MeshHeading>
<DescriptorName UI="D017060" MajorTopicYN="N">Patient Satisfaction</DescriptorName>
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<MeshHeading>
<DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName>
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<MeshHeading>
<DescriptorName UI="D016037" MajorTopicYN="N">Single-Blind Method</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D013594" MajorTopicYN="N">Syringes</DescriptorName>
<QualifierName UI="Q000191" MajorTopicYN="N">economics</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM">
<Keyword MajorTopicYN="N">anesthesia</Keyword>
<Keyword MajorTopicYN="N">cost effectiveness</Keyword>
<Keyword MajorTopicYN="N">laryngoscopy</Keyword>
<Keyword MajorTopicYN="N">office procedure</Keyword>
<Keyword MajorTopicYN="N">patient tolerance</Keyword>
</KeywordList>
</MedlineCitation>
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<Year>2014</Year>
<Month>2</Month>
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<Hour>6</Hour>
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<noCountry>
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<name sortKey="Smith, Libby J" sort="Smith, Libby J" uniqKey="Smith L" first="Libby J" last="Smith">Libby J. Smith</name>
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