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Discovery of epigenetic biomarkers for the noninvasive diagnosis of fetal disease

Identifieur interne : 008334 ( Main/Merge ); précédent : 008333; suivant : 008335

Discovery of epigenetic biomarkers for the noninvasive diagnosis of fetal disease

Auteurs : Kimberly Bunce [États-Unis] ; Tianjiao Chu [États-Unis] ; Urvashi Surti [États-Unis] ; William Allen Hogge [États-Unis] ; David G. Peters [États-Unis]

Source :

Prenatal Diagnosis [ 0197-3851 ] ; 2012-06.

RBID : ISTEX:AA48AB8E3ECA3FB3D48323B8DAEAFA830F1795A4

English descriptors

KwdEn :
- Aneuploidy, Biomarkers, Chem, Chiu, Chorionic villus sampling, Chromosome, Clin, Clin chem, Cpgs, Differentially, Differentially methylated, Dmrs, Epigenetic, Epigenetic biomarker discovery, Epityper, Fetal, Fetal alleles, Fetal aneuploidy, Fetal trisomy, Genome, Gestational, Gestational weeks, Hypermethylated, Hypothetical protein, Isoform, John wiley sons, Leung, Locus, Mass spectrometry, Maternal, Maternal leukocytes, Maternal plasma, Methylated, Methylation, Microarray, Microarray analysis, Noninvasive, Noninvasive detection, Noninvasive diagnosis, Placental, Potential biomarkers, Prenatal, Prenatal diagnosis, Primer, Proteinase inhibitor, Selective recovery, Trisomy.
Teeft :
- Aneuploidy, Biomarkers, Chem, Chiu, Chorionic villus sampling, Chromosome, Clin, Clin chem, Cpgs, Differentially, Differentially methylated, Dmrs, Epigenetic, Epigenetic biomarker discovery, Epityper, Fetal, Fetal alleles, Fetal aneuploidy, Fetal trisomy, Genome, Gestational, Gestational weeks, Hypermethylated, Hypothetical protein, Isoform, John wiley sons, Leung, Locus, Mass spectrometry, Maternal, Maternal leukocytes, Maternal plasma, Methylated, Methylation, Microarray, Microarray analysis, Noninvasive, Noninvasive detection, Noninvasive diagnosis, Placental, Potential biomarkers, Prenatal, Prenatal diagnosis, Primer, Proteinase inhibitor, Selective recovery, Trisomy.

Abstract

The primary goal of this study was to identify CpG sites in the human genome that are differentially methylated in DNA obtained from chorionic villus sampling (CVS) samples and gestational age‐matched maternal blood cell (MBC) samples.

Url:

https://api.istex.fr/document/AA48AB8E3ECA3FB3D48323B8DAEAFA830F1795A4/fulltext/pdf

DOI: 10.1002/pd.3853

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ISTEX:AA48AB8E3ECA3FB3D48323B8DAEAFA830F1795A4

Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aneuploidy</term>
<term>Biomarkers</term>
<term>Chem</term>
<term>Chiu</term>
<term>Chorionic villus sampling</term>
<term>Chromosome</term>
<term>Clin</term>
<term>Clin chem</term>
<term>Cpgs</term>
<term>Differentially</term>
<term>Differentially methylated</term>
<term>Dmrs</term>
<term>Epigenetic</term>
<term>Epigenetic biomarker discovery</term>
<term>Epityper</term>
<term>Fetal</term>
<term>Fetal alleles</term>
<term>Fetal aneuploidy</term>
<term>Fetal trisomy</term>
<term>Genome</term>
<term>Gestational</term>
<term>Gestational weeks</term>
<term>Hypermethylated</term>
<term>Hypothetical protein</term>
<term>Isoform</term>
<term>John wiley sons</term>
<term>Leung</term>
<term>Locus</term>
<term>Mass spectrometry</term>
<term>Maternal</term>
<term>Maternal leukocytes</term>
<term>Maternal plasma</term>
<term>Methylated</term>
<term>Methylation</term>
<term>Microarray</term>
<term>Microarray analysis</term>
<term>Noninvasive</term>
<term>Noninvasive detection</term>
<term>Noninvasive diagnosis</term>
<term>Placental</term>
<term>Potential biomarkers</term>
<term>Prenatal</term>
<term>Prenatal diagnosis</term>
<term>Primer</term>
<term>Proteinase inhibitor</term>
<term>Selective recovery</term>
<term>Trisomy</term>
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<keywords scheme="Teeft" xml:lang="en"><term>Aneuploidy</term>
<term>Biomarkers</term>
<term>Chem</term>
<term>Chiu</term>
<term>Chorionic villus sampling</term>
<term>Chromosome</term>
<term>Clin</term>
<term>Clin chem</term>
<term>Cpgs</term>
<term>Differentially</term>
<term>Differentially methylated</term>
<term>Dmrs</term>
<term>Epigenetic</term>
<term>Epigenetic biomarker discovery</term>
<term>Epityper</term>
<term>Fetal</term>
<term>Fetal alleles</term>
<term>Fetal aneuploidy</term>
<term>Fetal trisomy</term>
<term>Genome</term>
<term>Gestational</term>
<term>Gestational weeks</term>
<term>Hypermethylated</term>
<term>Hypothetical protein</term>
<term>Isoform</term>
<term>John wiley sons</term>
<term>Leung</term>
<term>Locus</term>
<term>Mass spectrometry</term>
<term>Maternal</term>
<term>Maternal leukocytes</term>
<term>Maternal plasma</term>
<term>Methylated</term>
<term>Methylation</term>
<term>Microarray</term>
<term>Microarray analysis</term>
<term>Noninvasive</term>
<term>Noninvasive detection</term>
<term>Noninvasive diagnosis</term>
<term>Placental</term>
<term>Potential biomarkers</term>
<term>Prenatal</term>
<term>Prenatal diagnosis</term>
<term>Primer</term>
<term>Proteinase inhibitor</term>
<term>Selective recovery</term>
<term>Trisomy</term>
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<front><div type="abstract">The primary goal of this study was to identify CpG sites in the human genome that are differentially methylated in DNA obtained from chorionic villus sampling (CVS) samples and gestational age‐matched maternal blood cell (MBC) samples.</div>
</front>
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Discovery of epigenetic biomarkers for the noninvasive diagnosis of fetal disease

Discovery of epigenetic biomarkers for the noninvasive diagnosis of fetal disease

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English descriptors

Abstract

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