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Association between Six Minute Walk Test and All-Cause Mortality, Coronary Heart Disease-Specific Mortality, and Incident Coronary Heart Disease

Identifieur interne : 003F75 ( Main/Merge ); précédent : 003F74; suivant : 003F76

Association between Six Minute Walk Test and All-Cause Mortality, Coronary Heart Disease-Specific Mortality, and Incident Coronary Heart Disease

Auteurs : Ali Yazdanyar ; Michael M. Aziz ; Paul L. Enright ; Daniel Edmundowicz ; Robert Boudreau ; Kim Sutton-Tyrell ; Lewis Kuller ; Anne B. Newman

Source :

Journal of aging and health [ 0898-2643 ] ; 2014.

RBID : PMC:4485950

Abstract

Objectives

To examine the association between six-minute walk test (6 MWT) performance and all-cause mortality, coronary heart disease mortality, and incident coronary heart disease in older adults.

Methods

We conducted a time-to-event analysis of 1,665 Cardiovascular Health Study participants with a 6 MWT and without prevalent cardiovascular disease.

Results

During a mean follow-up of 8 years, there were 305 incident coronary heart disease events, 504 deaths of which 100 were coronary heart disease-related deaths. The 6 MWT performance in the shortest two distance quintiles was associated with increased risk of all-cause mortality (290-338 meters: HR 1.7; 95% CI, 1.2-2.5; <290 meters: HR 2.1; 95% CI, 1.4-3.0). The adjusted risk of coronary heart disease mortality incident events among those with a 6 MWT <290 meters was not significant.

Discussion

Performance on the 6 MWT is independently associated with all-cause mortality and is of prognostic utility in community-dwelling older adults.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485950

DOI: 10.1177/0898264314525665
PubMed: 24695552
PubMed Central: 4485950

Links to Exploration step

PMC:4485950

Le document en format XML

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<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objectives</title>
<p id="P1">To examine the association between six-minute walk test (6 MWT) performance and all-cause mortality, coronary heart disease mortality, and incident coronary heart disease in older adults.</p>
</sec>
<sec id="S2"><title>Methods</title>
<p id="P2">We conducted a time-to-event analysis of 1,665 Cardiovascular Health Study participants with a 6 MWT and without prevalent cardiovascular disease.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">During a mean follow-up of 8 years, there were 305 incident coronary heart disease events, 504 deaths of which 100 were coronary heart disease-related deaths. The 6 MWT performance in the shortest two distance quintiles was associated with increased risk of all-cause mortality (290-338 meters: HR 1.7; 95% CI, 1.2-2.5; <290 meters: HR 2.1; 95% CI, 1.4-3.0). The adjusted risk of coronary heart disease mortality incident events among those with a 6 MWT <290 meters was not significant.</p>
</sec>
<sec id="S4"><title>Discussion</title>
<p id="P4">Performance on the 6 MWT is independently associated with all-cause mortality and is of prognostic utility in community-dwelling older adults.</p>
</sec>
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Association between Six Minute Walk Test and All-Cause Mortality, Coronary Heart Disease-Specific Mortality, and Incident Coronary Heart Disease

Association between Six Minute Walk Test and All-Cause Mortality, Coronary Heart Disease-Specific Mortality, and Incident Coronary Heart Disease

Source :

Abstract

Links toward previous steps (curation, corpus...)

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