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Effect of golimumab on carotid atherosclerotic disease measures and cardiovascular events in inflammatory arthritides.

Identifieur interne : 003313 ( Main/Merge ); précédent : 003312; suivant : 003314

Effect of golimumab on carotid atherosclerotic disease measures and cardiovascular events in inflammatory arthritides.

Auteurs : Mary Chester Wasko [États-Unis] ; Elizabeth C. Hsia ; Bruce Kirkham ; Pierre-Jean Touboul ; Roy Fleischmann ; Mark C. Genovese ; Eric L. Matteson ; Jiandong Lu ; Weichun Xu ; Mahboob U. Rahman

Source :

RBID : pubmed:24356481

Descripteurs français

English descriptors

Abstract

The objective of this study was to assess the effect of golimumab on carotid ultrasound measures and cardiovascular serious adverse events (SAEs) in patients with inflammatory arthritides.

DOI: 10.1097/RHU.0000000000000053
PubMed: 24356481

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pubmed:24356481

Le document en format XML

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<title xml:lang="en">Effect of golimumab on carotid atherosclerotic disease measures and cardiovascular events in inflammatory arthritides.</title>
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<name sortKey="Wasko, Mary Chester" sort="Wasko, Mary Chester" uniqKey="Wasko M" first="Mary Chester" last="Wasko">Mary Chester Wasko</name>
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<nlm:affiliation>From the *Allegheny Singer Research Institute, West Penn Allegheny Health System; †Temple University School of Medicine-Pittsburgh Campus, Pittsburgh, PA; ‡Janssen Research & Development, LLC, Spring House, PA; §University of Pennsylvania School of Medicine, Philadelphia, PA; ∥Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom; ¶Department of Neurology and Stroke Center, Hôpital Bichat, Paris, France; #Metroplex Clinical Research Center, Dallas, TX; **Stanford University, Palo Alto, CA; and ††Mayo Clinic College of Medicine, Rochester, MN.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
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<region type="state">Minnesota</region>
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<wicri:cityArea>From the *Allegheny Singer Research Institute, West Penn Allegheny Health System; †Temple University School of Medicine-Pittsburgh Campus, Pittsburgh, PA; ‡Janssen Research & Development, LLC, Spring House, PA; §University of Pennsylvania School of Medicine, Philadelphia, PA; ∥Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom; ¶Department of Neurology and Stroke Center, Hôpital Bichat, Paris, France; #Metroplex Clinical Research Center, Dallas, TX; **Stanford University, Palo Alto, CA; and ††Mayo Clinic College of Medicine, Rochester</wicri:cityArea>
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<name sortKey="Hsia, Elizabeth C" sort="Hsia, Elizabeth C" uniqKey="Hsia E" first="Elizabeth C" last="Hsia">Elizabeth C. Hsia</name>
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<name sortKey="Kirkham, Bruce" sort="Kirkham, Bruce" uniqKey="Kirkham B" first="Bruce" last="Kirkham">Bruce Kirkham</name>
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<name sortKey="Touboul, Pierre Jean" sort="Touboul, Pierre Jean" uniqKey="Touboul P" first="Pierre-Jean" last="Touboul">Pierre-Jean Touboul</name>
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<name sortKey="Fleischmann, Roy" sort="Fleischmann, Roy" uniqKey="Fleischmann R" first="Roy" last="Fleischmann">Roy Fleischmann</name>
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<name sortKey="Genovese, Mark C" sort="Genovese, Mark C" uniqKey="Genovese M" first="Mark C" last="Genovese">Mark C. Genovese</name>
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<name sortKey="Matteson, Eric L" sort="Matteson, Eric L" uniqKey="Matteson E" first="Eric L" last="Matteson">Eric L. Matteson</name>
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<name sortKey="Lu, Jiandong" sort="Lu, Jiandong" uniqKey="Lu J" first="Jiandong" last="Lu">Jiandong Lu</name>
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<name sortKey="Xu, Weichun" sort="Xu, Weichun" uniqKey="Xu W" first="Weichun" last="Xu">Weichun Xu</name>
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<nlm:affiliation>From the *Allegheny Singer Research Institute, West Penn Allegheny Health System; †Temple University School of Medicine-Pittsburgh Campus, Pittsburgh, PA; ‡Janssen Research & Development, LLC, Spring House, PA; §University of Pennsylvania School of Medicine, Philadelphia, PA; ∥Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom; ¶Department of Neurology and Stroke Center, Hôpital Bichat, Paris, France; #Metroplex Clinical Research Center, Dallas, TX; **Stanford University, Palo Alto, CA; and ††Mayo Clinic College of Medicine, Rochester, MN.</nlm:affiliation>
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<title level="j">Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases</title>
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<term>Antibodies, Monoclonal (pharmacology)</term>
<term>Antibodies, Monoclonal (therapeutic use)</term>
<term>Antirheumatic Agents (therapeutic use)</term>
<term>Arthritis (drug therapy)</term>
<term>Cardiovascular Diseases (diagnostic imaging)</term>
<term>Cardiovascular Diseases (epidemiology)</term>
<term>Carotid Arteries (diagnostic imaging)</term>
<term>Carotid Arteries (drug effects)</term>
<term>Carotid Artery Diseases (diagnostic imaging)</term>
<term>Carotid Artery Diseases (epidemiology)</term>
<term>Carotid Intima-Media Thickness</term>
<term>Dose-Response Relationship, Drug</term>
<term>Double-Blind Method</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Incidence</term>
<term>Male</term>
<term>Methotrexate (therapeutic use)</term>
<term>Middle Aged</term>
<term>Risk Factors</term>
<term>Treatment Outcome</term>
<term>Ultrasonography, Interventional</term>
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<term>Anticorps monoclonaux (effets indésirables)</term>
<term>Anticorps monoclonaux (pharmacologie)</term>
<term>Anticorps monoclonaux (usage thérapeutique)</term>
<term>Antirhumatismaux (usage thérapeutique)</term>
<term>Arthrite (traitement médicamenteux)</term>
<term>Artères carotides ()</term>
<term>Artères carotides (imagerie diagnostique)</term>
<term>Artériopathies carotidiennes (imagerie diagnostique)</term>
<term>Artériopathies carotidiennes (épidémiologie)</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Incidence</term>
<term>Maladies cardiovasculaires (imagerie diagnostique)</term>
<term>Maladies cardiovasculaires (épidémiologie)</term>
<term>Mâle</term>
<term>Méthode en double aveugle</term>
<term>Méthotrexate (usage thérapeutique)</term>
<term>Relation dose-effet des médicaments</term>
<term>Résultat thérapeutique</term>
<term>Échographie interventionnelle</term>
<term>Épaisseur intima-média carotidienne</term>
<term>Études de suivi</term>
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<term>Antibodies, Monoclonal</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en">
<term>Antibodies, Monoclonal</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en">
<term>Antibodies, Monoclonal</term>
<term>Antirheumatic Agents</term>
<term>Methotrexate</term>
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<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en">
<term>Cardiovascular Diseases</term>
<term>Carotid Arteries</term>
<term>Carotid Artery Diseases</term>
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<keywords scheme="MESH" qualifier="drug effects" xml:lang="en">
<term>Carotid Arteries</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en">
<term>Arthritis</term>
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<term>Anticorps monoclonaux</term>
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<term>Cardiovascular Diseases</term>
<term>Carotid Artery Diseases</term>
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<term>Anticorps monoclonaux</term>
<term>Antirhumatismaux</term>
<term>Méthotrexate</term>
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<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr">
<term>Artériopathies carotidiennes</term>
<term>Maladies cardiovasculaires</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Carotid Intima-Media Thickness</term>
<term>Dose-Response Relationship, Drug</term>
<term>Double-Blind Method</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Incidence</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Risk Factors</term>
<term>Treatment Outcome</term>
<term>Ultrasonography, Interventional</term>
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<keywords scheme="MESH" xml:lang="fr">
<term>Adulte d'âge moyen</term>
<term>Artères carotides</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Incidence</term>
<term>Mâle</term>
<term>Méthode en double aveugle</term>
<term>Relation dose-effet des médicaments</term>
<term>Résultat thérapeutique</term>
<term>Échographie interventionnelle</term>
<term>Épaisseur intima-média carotidienne</term>
<term>Études de suivi</term>
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<front>
<div type="abstract" xml:lang="en">The objective of this study was to assess the effect of golimumab on carotid ultrasound measures and cardiovascular serious adverse events (SAEs) in patients with inflammatory arthritides.</div>
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