Effect of golimumab on carotid atherosclerotic disease measures and cardiovascular events in inflammatory arthritides.
Identifieur interne : 003313 ( Main/Merge ); précédent : 003312; suivant : 003314Effect of golimumab on carotid atherosclerotic disease measures and cardiovascular events in inflammatory arthritides.
Auteurs : Mary Chester Wasko [États-Unis] ; Elizabeth C. Hsia ; Bruce Kirkham ; Pierre-Jean Touboul ; Roy Fleischmann ; Mark C. Genovese ; Eric L. Matteson ; Jiandong Lu ; Weichun Xu ; Mahboob U. RahmanSource :
- Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases [ 1536-7355 ] ; 2014.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Anticorps monoclonaux (effets indésirables), Anticorps monoclonaux (pharmacologie), Anticorps monoclonaux (usage thérapeutique), Antirhumatismaux (usage thérapeutique), Arthrite (traitement médicamenteux), Artères carotides (), Artères carotides (imagerie diagnostique), Artériopathies carotidiennes (imagerie diagnostique), Artériopathies carotidiennes (épidémiologie), Facteurs de risque, Femelle, Humains, Incidence, Maladies cardiovasculaires (imagerie diagnostique), Maladies cardiovasculaires (épidémiologie), Mâle, Méthode en double aveugle, Méthotrexate (usage thérapeutique), Relation dose-effet des médicaments, Résultat thérapeutique, Échographie interventionnelle, Épaisseur intima-média carotidienne, Études de suivi.
- MESH :
- effets indésirables : Anticorps monoclonaux.
- imagerie diagnostique : Artères carotides, Artériopathies carotidiennes, Maladies cardiovasculaires.
- pharmacologie : Anticorps monoclonaux.
- traitement médicamenteux : Arthrite.
- usage thérapeutique : Anticorps monoclonaux, Antirhumatismaux, Méthotrexate.
- épidémiologie : Artériopathies carotidiennes, Maladies cardiovasculaires.
- Adulte d'âge moyen, Artères carotides, Facteurs de risque, Femelle, Humains, Incidence, Mâle, Méthode en double aveugle, Relation dose-effet des médicaments, Résultat thérapeutique, Échographie interventionnelle, Épaisseur intima-média carotidienne, Études de suivi.
English descriptors
- KwdEn :
- Antibodies, Monoclonal (adverse effects), Antibodies, Monoclonal (pharmacology), Antibodies, Monoclonal (therapeutic use), Antirheumatic Agents (therapeutic use), Arthritis (drug therapy), Cardiovascular Diseases (diagnostic imaging), Cardiovascular Diseases (epidemiology), Carotid Arteries (diagnostic imaging), Carotid Arteries (drug effects), Carotid Artery Diseases (diagnostic imaging), Carotid Artery Diseases (epidemiology), Carotid Intima-Media Thickness, Dose-Response Relationship, Drug, Double-Blind Method, Female, Follow-Up Studies, Humans, Incidence, Male, Methotrexate (therapeutic use), Middle Aged, Risk Factors, Treatment Outcome, Ultrasonography, Interventional.
- MESH :
- chemical , adverse effects : Antibodies, Monoclonal.
- chemical , pharmacology : Antibodies, Monoclonal.
- chemical , therapeutic use : Antibodies, Monoclonal, Antirheumatic Agents, Methotrexate.
- diagnostic imaging : Cardiovascular Diseases, Carotid Arteries, Carotid Artery Diseases.
- drug effects : Carotid Arteries.
- drug therapy : Arthritis.
- epidemiology : Cardiovascular Diseases, Carotid Artery Diseases.
- Carotid Intima-Media Thickness, Dose-Response Relationship, Drug, Double-Blind Method, Female, Follow-Up Studies, Humans, Incidence, Male, Middle Aged, Risk Factors, Treatment Outcome, Ultrasonography, Interventional.
Abstract
The objective of this study was to assess the effect of golimumab on carotid ultrasound measures and cardiovascular serious adverse events (SAEs) in patients with inflammatory arthritides.
DOI: 10.1097/RHU.0000000000000053
PubMed: 24356481
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pubmed:24356481Le document en format XML
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<author><name sortKey="Wasko, Mary Chester" sort="Wasko, Mary Chester" uniqKey="Wasko M" first="Mary Chester" last="Wasko">Mary Chester Wasko</name>
<affiliation wicri:level="2"><nlm:affiliation>From the *Allegheny Singer Research Institute, West Penn Allegheny Health System; †Temple University School of Medicine-Pittsburgh Campus, Pittsburgh, PA; ‡Janssen Research & Development, LLC, Spring House, PA; §University of Pennsylvania School of Medicine, Philadelphia, PA; ∥Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom; ¶Department of Neurology and Stroke Center, Hôpital Bichat, Paris, France; #Metroplex Clinical Research Center, Dallas, TX; **Stanford University, Palo Alto, CA; and ††Mayo Clinic College of Medicine, Rochester, MN.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Minnesota</region>
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<wicri:cityArea>From the *Allegheny Singer Research Institute, West Penn Allegheny Health System; †Temple University School of Medicine-Pittsburgh Campus, Pittsburgh, PA; ‡Janssen Research & Development, LLC, Spring House, PA; §University of Pennsylvania School of Medicine, Philadelphia, PA; ∥Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom; ¶Department of Neurology and Stroke Center, Hôpital Bichat, Paris, France; #Metroplex Clinical Research Center, Dallas, TX; **Stanford University, Palo Alto, CA; and ††Mayo Clinic College of Medicine, Rochester</wicri:cityArea>
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<author><name sortKey="Rahman, Mahboob U" sort="Rahman, Mahboob U" uniqKey="Rahman M" first="Mahboob U" last="Rahman">Mahboob U. Rahman</name>
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<affiliation wicri:level="2"><nlm:affiliation>From the *Allegheny Singer Research Institute, West Penn Allegheny Health System; †Temple University School of Medicine-Pittsburgh Campus, Pittsburgh, PA; ‡Janssen Research & Development, LLC, Spring House, PA; §University of Pennsylvania School of Medicine, Philadelphia, PA; ∥Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom; ¶Department of Neurology and Stroke Center, Hôpital Bichat, Paris, France; #Metroplex Clinical Research Center, Dallas, TX; **Stanford University, Palo Alto, CA; and ††Mayo Clinic College of Medicine, Rochester, MN.</nlm:affiliation>
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<wicri:cityArea>From the *Allegheny Singer Research Institute, West Penn Allegheny Health System; †Temple University School of Medicine-Pittsburgh Campus, Pittsburgh, PA; ‡Janssen Research & Development, LLC, Spring House, PA; §University of Pennsylvania School of Medicine, Philadelphia, PA; ∥Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom; ¶Department of Neurology and Stroke Center, Hôpital Bichat, Paris, France; #Metroplex Clinical Research Center, Dallas, TX; **Stanford University, Palo Alto, CA; and ††Mayo Clinic College of Medicine, Rochester</wicri:cityArea>
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<term>Antibodies, Monoclonal (pharmacology)</term>
<term>Antibodies, Monoclonal (therapeutic use)</term>
<term>Antirheumatic Agents (therapeutic use)</term>
<term>Arthritis (drug therapy)</term>
<term>Cardiovascular Diseases (diagnostic imaging)</term>
<term>Cardiovascular Diseases (epidemiology)</term>
<term>Carotid Arteries (diagnostic imaging)</term>
<term>Carotid Arteries (drug effects)</term>
<term>Carotid Artery Diseases (diagnostic imaging)</term>
<term>Carotid Artery Diseases (epidemiology)</term>
<term>Carotid Intima-Media Thickness</term>
<term>Dose-Response Relationship, Drug</term>
<term>Double-Blind Method</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Incidence</term>
<term>Male</term>
<term>Methotrexate (therapeutic use)</term>
<term>Middle Aged</term>
<term>Risk Factors</term>
<term>Treatment Outcome</term>
<term>Ultrasonography, Interventional</term>
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<term>Anticorps monoclonaux (effets indésirables)</term>
<term>Anticorps monoclonaux (pharmacologie)</term>
<term>Anticorps monoclonaux (usage thérapeutique)</term>
<term>Antirhumatismaux (usage thérapeutique)</term>
<term>Arthrite (traitement médicamenteux)</term>
<term>Artères carotides ()</term>
<term>Artères carotides (imagerie diagnostique)</term>
<term>Artériopathies carotidiennes (imagerie diagnostique)</term>
<term>Artériopathies carotidiennes (épidémiologie)</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Incidence</term>
<term>Maladies cardiovasculaires (imagerie diagnostique)</term>
<term>Maladies cardiovasculaires (épidémiologie)</term>
<term>Mâle</term>
<term>Méthode en double aveugle</term>
<term>Méthotrexate (usage thérapeutique)</term>
<term>Relation dose-effet des médicaments</term>
<term>Résultat thérapeutique</term>
<term>Échographie interventionnelle</term>
<term>Épaisseur intima-média carotidienne</term>
<term>Études de suivi</term>
</keywords>
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<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Antibodies, Monoclonal</term>
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<term>Antirheumatic Agents</term>
<term>Methotrexate</term>
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<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Cardiovascular Diseases</term>
<term>Carotid Arteries</term>
<term>Carotid Artery Diseases</term>
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<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Carotid Arteries</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Arthritis</term>
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<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Anticorps monoclonaux</term>
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<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Cardiovascular Diseases</term>
<term>Carotid Artery Diseases</term>
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<term>Artériopathies carotidiennes</term>
<term>Maladies cardiovasculaires</term>
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<term>Méthotrexate</term>
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<term>Maladies cardiovasculaires</term>
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<keywords scheme="MESH" xml:lang="en"><term>Carotid Intima-Media Thickness</term>
<term>Dose-Response Relationship, Drug</term>
<term>Double-Blind Method</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Incidence</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Risk Factors</term>
<term>Treatment Outcome</term>
<term>Ultrasonography, Interventional</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Artères carotides</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Incidence</term>
<term>Mâle</term>
<term>Méthode en double aveugle</term>
<term>Relation dose-effet des médicaments</term>
<term>Résultat thérapeutique</term>
<term>Échographie interventionnelle</term>
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<front><div type="abstract" xml:lang="en">The objective of this study was to assess the effect of golimumab on carotid ultrasound measures and cardiovascular serious adverse events (SAEs) in patients with inflammatory arthritides.</div>
</front>
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