Impact of aggressive histology and location of primary tumor on the efficacy of surgical therapy for peritoneal carcinomatosis of colorectal origin.
Identifieur interne : 002971 ( Main/Merge ); précédent : 002970; suivant : 002972Impact of aggressive histology and location of primary tumor on the efficacy of surgical therapy for peritoneal carcinomatosis of colorectal origin.
Auteurs : Joshua Winer [États-Unis] ; Mazen Zenati ; Lekshmi Ramalingam ; Heather Jones ; Amer Zureikat ; Matthew Holtzman ; Kenneth Lee ; Steven Ahrendt ; James Pingpank ; Herbert J. Zeh ; David L. Bartlett ; Haroon A. ChoudrySource :
- Annals of surgical oncology [ 1534-4681 ] ; 2014.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Association thérapeutique, Carcinome à cellules en bague à chaton (), Carcinome à cellules en bague à chaton (mortalité), Carcinome à cellules en bague à chaton (secondaire), Carcinome à cellules en bague à chaton (traitement médicamenteux), Femelle, Humains, Hyperthermie provoquée, Mâle, Perfusion régionale de chimiothérapie anticancéreuse, Pronostic, Protocoles de polychimiothérapie antinéoplasique (usage thérapeutique), Stade de la tumeur, Taux de survie, Tumeurs colorectales (), Tumeurs colorectales (anatomopathologie), Tumeurs colorectales (mortalité), Tumeurs colorectales (traitement médicamenteux), Tumeurs de l'appendice (), Tumeurs de l'appendice (anatomopathologie), Tumeurs de l'appendice (mortalité), Tumeurs de l'appendice (traitement médicamenteux), Tumeurs du péritoine (), Tumeurs du péritoine (mortalité), Tumeurs du péritoine (secondaire), Tumeurs du péritoine (traitement médicamenteux), Études de suivi, Études prospectives.
- MESH :
- anatomopathologie : Tumeurs colorectales, Tumeurs de l'appendice.
- mortalité : Carcinome à cellules en bague à chaton, Tumeurs colorectales, Tumeurs de l'appendice, Tumeurs du péritoine.
- secondaire : Carcinome à cellules en bague à chaton, Tumeurs du péritoine.
- traitement médicamenteux : Carcinome à cellules en bague à chaton, Tumeurs colorectales, Tumeurs de l'appendice, Tumeurs du péritoine.
- usage thérapeutique : Protocoles de polychimiothérapie antinéoplasique.
- Adulte d'âge moyen, Association thérapeutique, Carcinome à cellules en bague à chaton, Femelle, Humains, Hyperthermie provoquée, Mâle, Perfusion régionale de chimiothérapie anticancéreuse, Pronostic, Stade de la tumeur, Taux de survie, Tumeurs colorectales, Tumeurs de l'appendice, Tumeurs du péritoine, Études de suivi, Études prospectives.
English descriptors
- KwdEn :
- Antineoplastic Combined Chemotherapy Protocols (therapeutic use), Appendiceal Neoplasms (drug therapy), Appendiceal Neoplasms (mortality), Appendiceal Neoplasms (pathology), Appendiceal Neoplasms (surgery), Carcinoma, Signet Ring Cell (drug therapy), Carcinoma, Signet Ring Cell (mortality), Carcinoma, Signet Ring Cell (secondary), Carcinoma, Signet Ring Cell (surgery), Chemotherapy, Cancer, Regional Perfusion, Colorectal Neoplasms (drug therapy), Colorectal Neoplasms (mortality), Colorectal Neoplasms (pathology), Colorectal Neoplasms (surgery), Combined Modality Therapy, Female, Follow-Up Studies, Humans, Hyperthermia, Induced, Male, Middle Aged, Neoplasm Staging, Peritoneal Neoplasms (drug therapy), Peritoneal Neoplasms (mortality), Peritoneal Neoplasms (secondary), Peritoneal Neoplasms (surgery), Prognosis, Prospective Studies, Survival Rate.
- MESH :
- drug therapy : Appendiceal Neoplasms, Carcinoma, Signet Ring Cell, Colorectal Neoplasms, Peritoneal Neoplasms.
- mortality : Appendiceal Neoplasms, Carcinoma, Signet Ring Cell, Colorectal Neoplasms, Peritoneal Neoplasms.
- pathology : Appendiceal Neoplasms, Colorectal Neoplasms.
- secondary : Carcinoma, Signet Ring Cell, Peritoneal Neoplasms.
- surgery : Appendiceal Neoplasms, Carcinoma, Signet Ring Cell, Colorectal Neoplasms, Peritoneal Neoplasms.
- therapeutic use : Antineoplastic Combined Chemotherapy Protocols.
- Chemotherapy, Cancer, Regional Perfusion, Combined Modality Therapy, Female, Follow-Up Studies, Humans, Hyperthermia, Induced, Male, Middle Aged, Neoplasm Staging, Prognosis, Prospective Studies, Survival Rate.
Abstract
Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemoperfusion (HIPEC) for peritoneal carcinomatosis (PC) of colorectal origin increases survival (OS) compared to systemic chemotherapy alone. Signet ring histology demonstrates aggressive behavior with poor survival. We sought to determine whether CRS/HIPEC increases survival in this subset of patients.
DOI: 10.1245/s10434-013-3328-4
PubMed: 24201745
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pubmed:24201745Le document en format XML
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<author><name sortKey="Winer, Joshua" sort="Winer, Joshua" uniqKey="Winer J" first="Joshua" last="Winer">Joshua Winer</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antineoplastic Combined Chemotherapy Protocols (therapeutic use)</term>
<term>Appendiceal Neoplasms (drug therapy)</term>
<term>Appendiceal Neoplasms (mortality)</term>
<term>Appendiceal Neoplasms (pathology)</term>
<term>Appendiceal Neoplasms (surgery)</term>
<term>Carcinoma, Signet Ring Cell (drug therapy)</term>
<term>Carcinoma, Signet Ring Cell (mortality)</term>
<term>Carcinoma, Signet Ring Cell (secondary)</term>
<term>Carcinoma, Signet Ring Cell (surgery)</term>
<term>Chemotherapy, Cancer, Regional Perfusion</term>
<term>Colorectal Neoplasms (drug therapy)</term>
<term>Colorectal Neoplasms (mortality)</term>
<term>Colorectal Neoplasms (pathology)</term>
<term>Colorectal Neoplasms (surgery)</term>
<term>Combined Modality Therapy</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Hyperthermia, Induced</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasm Staging</term>
<term>Peritoneal Neoplasms (drug therapy)</term>
<term>Peritoneal Neoplasms (mortality)</term>
<term>Peritoneal Neoplasms (secondary)</term>
<term>Peritoneal Neoplasms (surgery)</term>
<term>Prognosis</term>
<term>Prospective Studies</term>
<term>Survival Rate</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Association thérapeutique</term>
<term>Carcinome à cellules en bague à chaton ()</term>
<term>Carcinome à cellules en bague à chaton (mortalité)</term>
<term>Carcinome à cellules en bague à chaton (secondaire)</term>
<term>Carcinome à cellules en bague à chaton (traitement médicamenteux)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Hyperthermie provoquée</term>
<term>Mâle</term>
<term>Perfusion régionale de chimiothérapie anticancéreuse</term>
<term>Pronostic</term>
<term>Protocoles de polychimiothérapie antinéoplasique (usage thérapeutique)</term>
<term>Stade de la tumeur</term>
<term>Taux de survie</term>
<term>Tumeurs colorectales ()</term>
<term>Tumeurs colorectales (anatomopathologie)</term>
<term>Tumeurs colorectales (mortalité)</term>
<term>Tumeurs colorectales (traitement médicamenteux)</term>
<term>Tumeurs de l'appendice ()</term>
<term>Tumeurs de l'appendice (anatomopathologie)</term>
<term>Tumeurs de l'appendice (mortalité)</term>
<term>Tumeurs de l'appendice (traitement médicamenteux)</term>
<term>Tumeurs du péritoine ()</term>
<term>Tumeurs du péritoine (mortalité)</term>
<term>Tumeurs du péritoine (secondaire)</term>
<term>Tumeurs du péritoine (traitement médicamenteux)</term>
<term>Études de suivi</term>
<term>Études prospectives</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Tumeurs colorectales</term>
<term>Tumeurs de l'appendice</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Appendiceal Neoplasms</term>
<term>Carcinoma, Signet Ring Cell</term>
<term>Colorectal Neoplasms</term>
<term>Peritoneal Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Appendiceal Neoplasms</term>
<term>Carcinoma, Signet Ring Cell</term>
<term>Colorectal Neoplasms</term>
<term>Peritoneal Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Carcinome à cellules en bague à chaton</term>
<term>Tumeurs colorectales</term>
<term>Tumeurs de l'appendice</term>
<term>Tumeurs du péritoine</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Appendiceal Neoplasms</term>
<term>Colorectal Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="secondaire" xml:lang="fr"><term>Carcinome à cellules en bague à chaton</term>
<term>Tumeurs du péritoine</term>
</keywords>
<keywords scheme="MESH" qualifier="secondary" xml:lang="en"><term>Carcinoma, Signet Ring Cell</term>
<term>Peritoneal Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Appendiceal Neoplasms</term>
<term>Carcinoma, Signet Ring Cell</term>
<term>Colorectal Neoplasms</term>
<term>Peritoneal Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="therapeutic use" xml:lang="en"><term>Antineoplastic Combined Chemotherapy Protocols</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Carcinome à cellules en bague à chaton</term>
<term>Tumeurs colorectales</term>
<term>Tumeurs de l'appendice</term>
<term>Tumeurs du péritoine</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Protocoles de polychimiothérapie antinéoplasique</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Chemotherapy, Cancer, Regional Perfusion</term>
<term>Combined Modality Therapy</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Hyperthermia, Induced</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasm Staging</term>
<term>Prognosis</term>
<term>Prospective Studies</term>
<term>Survival Rate</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Association thérapeutique</term>
<term>Carcinome à cellules en bague à chaton</term>
<term>Femelle</term>
<term>Humains</term>
<term>Hyperthermie provoquée</term>
<term>Mâle</term>
<term>Perfusion régionale de chimiothérapie anticancéreuse</term>
<term>Pronostic</term>
<term>Stade de la tumeur</term>
<term>Taux de survie</term>
<term>Tumeurs colorectales</term>
<term>Tumeurs de l'appendice</term>
<term>Tumeurs du péritoine</term>
<term>Études de suivi</term>
<term>Études prospectives</term>
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<front><div type="abstract" xml:lang="en">Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemoperfusion (HIPEC) for peritoneal carcinomatosis (PC) of colorectal origin increases survival (OS) compared to systemic chemotherapy alone. Signet ring histology demonstrates aggressive behavior with poor survival. We sought to determine whether CRS/HIPEC increases survival in this subset of patients.</div>
</front>
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