PittsburghV1, Main, Merge, bibRecord, 000F53

The Centiloid Project: Standardizing Quantitative Amyloid Plaque Estimation by PET

Identifieur interne : 000F53 ( Main/Merge ); précédent : 000F52; suivant : 000F54

The Centiloid Project: Standardizing Quantitative Amyloid Plaque Estimation by PET

Auteurs : William E. Klunk [États-Unis] ; Robert A. Koeppe [États-Unis] ; Julie C. Price [États-Unis] ; Tammie Benzinger [États-Unis] ; Michael D. Devous [États-Unis] ; William Jagust ; Keith Johnson [États-Unis] ; Chester A. Mathis [États-Unis] ; Davneet Minhas [États-Unis] ; Michael J. Pontecorvo [États-Unis] ; Christopher C. Rowe [Australie] ; Daniel Skovronsky [États-Unis] ; Mark Mintun [États-Unis]

Source :

Alzheimer's & dementia : the journal of the Alzheimer's Association [ 1552-5260 ] ; 2014.

RBID : PMC:4300247

Descripteurs français

KwdFr :
- Adulte d'âge moyen, Amyloïde (métabolisme), Calibrage, Dérivés de l'aniline, Encéphale (imagerie diagnostique), Encéphale (métabolisme), Fluorodésoxyglucose F18, Humains, Interprétation d'image assistée par ordinateur, Maladie d'Alzheimer (imagerie diagnostique), Maladie d'Alzheimer (métabolisme), Plaque amyloïde (imagerie diagnostique), Plaque amyloïde (métabolisme), Radiopharmaceutiques, Sujet âgé, Sujet âgé de 80 ans ou plus, Thiazoles, Tomographie par émission de positons (normes).
MESH :
- imagerie diagnostique : Encéphale, Maladie d'Alzheimer, Plaque amyloïde.
- métabolisme : Amyloïde, Encéphale, Maladie d'Alzheimer, Plaque amyloïde.
- normes : Tomographie par émission de positons.
- Adulte d'âge moyen, Calibrage, Dérivés de l'aniline, Fluorodésoxyglucose F18, Humains, Interprétation d'image assistée par ordinateur, Radiopharmaceutiques, Sujet âgé, Sujet âgé de 80 ans ou plus, Thiazoles.

English descriptors

KwdEn :
- Aged, Aged, 80 and over, Alzheimer Disease (diagnostic imaging), Alzheimer Disease (metabolism), Amyloid (metabolism), Aniline Compounds, Brain (diagnostic imaging), Brain (metabolism), Calibration, Fluorodeoxyglucose F18, Humans, Image Interpretation, Computer-Assisted, Middle Aged, Plaque, Amyloid (diagnostic imaging), Plaque, Amyloid (metabolism), Positron-Emission Tomography (standards), Radiopharmaceuticals, Thiazoles.
MESH :
- chemical , metabolism : Amyloid.
- diagnostic imaging : Alzheimer Disease, Brain, Plaque, Amyloid.
- metabolism : Alzheimer Disease, Brain, Plaque, Amyloid.
- standards : Positron-Emission Tomography.
- Aged, Aged, 80 and over, Aniline Compounds, Calibration, Fluorodeoxyglucose F18, Humans, Image Interpretation, Computer-Assisted, Middle Aged, Radiopharmaceuticals, Thiazoles.

Abstract

Although amyloid imaging with PiB-PET, and now with F-18-labelled tracers, has produced remarkably consistent qualitative findings across a large number of centers, there has been considerable variability in the exact numbers reported as quantitative outcome measures of tracer retention. In some cases this is as trivial as the choice of units, in some cases it is scanner dependent, and of course, different tracers yield different numbers. Our working group was formed to standardize quantitative amyloid imaging measures by scaling the outcome of each particular analysis method or tracer to a 0 to 100 scale, anchored by young controls (≤45 years) and typical Alzheimer’s disease patients. The units of this scale have been named “Centiloids.” Basically, we describe a “standard” method of analyzing PiB PET data and then a method for scaling any “non-standard” method of PiB PET analysis (or any other tracer) to the Centiloid scale.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300247

DOI: 10.1016/j.jalz.2014.07.003
PubMed: 25443857
PubMed Central: 4300247

Links to Exploration step

PMC:4300247

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Centiloid Project: Standardizing Quantitative Amyloid Plaque Estimation by PET</title>
<author><name sortKey="Klunk, William E" sort="Klunk, William E" uniqKey="Klunk W" first="William E." last="Klunk">William E. Klunk</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Departments of Psychiatry and Neurology, University of Pittsburgh, 3811 O’Hara St.,<italic>Pittsburgh</italic>
. PA 15213-2582, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>. PA 15213-2582</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Koeppe, Robert A" sort="Koeppe, Robert A" uniqKey="Koeppe R" first="Robert A." last="Koeppe">Robert A. Koeppe</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Department of Radiology, University of Michigan, 1301 E Medical Center Drive, Ann Arbor MI, 48109, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Radiology, University of Michigan, 1301 E Medical Center Drive, Ann Arbor MI, 48109</wicri:regionArea>
<wicri:noRegion>48109</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Price, Julie C" sort="Price, Julie C" uniqKey="Price J" first="Julie C." last="Price">Julie C. Price</name>
<affiliation wicri:level="4"><nlm:aff id="A3">Department of Radiology, University of Pittsburgh, 200 Lothrop St., Pittsburgh, PA 15213-2582, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Radiology, University of Pittsburgh, 200 Lothrop St., Pittsburgh, PA 15213-2582</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">Pittsburgh</settlement>
</placeName>
<orgName type="university">Université de Pittsburgh</orgName>
</affiliation>
</author>
<author><name sortKey="Benzinger, Tammie" sort="Benzinger, Tammie" uniqKey="Benzinger T" first="Tammie" last="Benzinger">Tammie Benzinger</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Departments of Radiology and Neurosurgery, Washington University, Saint Louis, MO, 63110, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Radiology and Neurosurgery, Washington University, Saint Louis, MO, 63110</wicri:regionArea>
<wicri:noRegion>63110</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Devous, Michael D" sort="Devous, Michael D" uniqKey="Devous M" first="Michael D." last="Devous">Michael D. Devous</name>
<affiliation wicri:level="2"><nlm:aff id="A5">Departments of Neurology and Radiology, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9061, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Neurology and Radiology, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9061</wicri:regionArea>
<placeName><region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jagust, William" sort="Jagust, William" uniqKey="Jagust W" first="William" last="Jagust">William Jagust</name>
<affiliation><nlm:aff id="A6">Helen Wills Neuroscience Institute, University of California Berkeley</nlm:aff>
<wicri:noCountry code="subfield">University of California Berkeley</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Johnson, Keith" sort="Johnson, Keith" uniqKey="Johnson K" first="Keith" last="Johnson">Keith Johnson</name>
<affiliation wicri:level="2"><nlm:aff id="A7">Departments of Radiology and Neurology, Massachusetts General Hospital, 33 Fruit St., Boston, MA 02114, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Radiology and Neurology, Massachusetts General Hospital, 33 Fruit St., Boston, MA 02114</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mathis, Chester A" sort="Mathis, Chester A" uniqKey="Mathis C" first="Chester A." last="Mathis">Chester A. Mathis</name>
<affiliation wicri:level="4"><nlm:aff id="A8">Departments of Radiology, Pharmacology and Biological Chemistry, and Pharmaceutical Sciences, University of Pittsburgh, 200 Lothrop St., Pittsburgh, PA 15213-2582, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Radiology, Pharmacology and Biological Chemistry, and Pharmaceutical Sciences, University of Pittsburgh, 200 Lothrop St., Pittsburgh, PA 15213-2582</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">Pittsburgh</settlement>
</placeName>
<orgName type="university">Université de Pittsburgh</orgName>
</affiliation>
</author>
<author><name sortKey="Minhas, Davneet" sort="Minhas, Davneet" uniqKey="Minhas D" first="Davneet" last="Minhas">Davneet Minhas</name>
<affiliation wicri:level="4"><nlm:aff id="A9">Department of Radiology, University of Pittsburgh, 200 Lothrop St., Pittsburgh, PA 15213-2582, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Radiology, University of Pittsburgh, 200 Lothrop St., Pittsburgh, PA 15213-2582</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">Pittsburgh</settlement>
</placeName>
<orgName type="university">Université de Pittsburgh</orgName>
</affiliation>
</author>
<author><name sortKey="Pontecorvo, Michael J" sort="Pontecorvo, Michael J" uniqKey="Pontecorvo M" first="Michael J." last="Pontecorvo">Michael J. Pontecorvo</name>
<affiliation wicri:level="2"><nlm:aff id="A10">Avid Radiopharmaceuticals, 3711 Market St., Philadelphia, PA 19104</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>Avid Radiopharmaceuticals, 3711 Market St., Philadelphia</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Rowe, Christopher C" sort="Rowe, Christopher C" uniqKey="Rowe C" first="Christopher C." last="Rowe">Christopher C. Rowe</name>
<affiliation wicri:level="1"><nlm:aff id="A11">Department of Nuclear Medicine and Centre for PET, Austin Health, Melbourne, VIC 3103, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Nuclear Medicine and Centre for PET, Austin Health, Melbourne, VIC 3103</wicri:regionArea>
<wicri:noRegion>VIC 3103</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Skovronsky, Daniel" sort="Skovronsky, Daniel" uniqKey="Skovronsky D" first="Daniel" last="Skovronsky">Daniel Skovronsky</name>
<affiliation wicri:level="2"><nlm:aff id="A10">Avid Radiopharmaceuticals, 3711 Market St., Philadelphia, PA 19104</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>Avid Radiopharmaceuticals, 3711 Market St., Philadelphia</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Mintun, Mark" sort="Mintun, Mark" uniqKey="Mintun M" first="Mark" last="Mintun">Mark Mintun</name>
<affiliation wicri:level="2"><nlm:aff id="A10">Avid Radiopharmaceuticals, 3711 Market St., Philadelphia, PA 19104</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>Avid Radiopharmaceuticals, 3711 Market St., Philadelphia</wicri:cityArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">25443857</idno>
<idno type="pmc">4300247</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300247</idno>
<idno type="RBID">PMC:4300247</idno>
<idno type="doi">10.1016/j.jalz.2014.07.003</idno>
<date when="2014">2014</date>
<idno type="wicri:Area/Pmc/Corpus">001081</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001081</idno>
<idno type="wicri:Area/Pmc/Curation">001056</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001056</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000395</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000395</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">000832</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000832</idno>
<idno type="wicri:Area/PubMed/Curation">000832</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000832</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000832</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000832</idno>
<idno type="wicri:Area/Ncbi/Merge">004071</idno>
<idno type="wicri:Area/Ncbi/Curation">004071</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">004071</idno>
<idno type="wicri:doubleKey">1552-5260:2014:Klunk W:the:centiloid:project</idno>
<idno type="wicri:Area/Main/Merge">000F53</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Centiloid Project: Standardizing Quantitative Amyloid Plaque Estimation by PET</title>
<author><name sortKey="Klunk, William E" sort="Klunk, William E" uniqKey="Klunk W" first="William E." last="Klunk">William E. Klunk</name>
<affiliation wicri:level="1"><nlm:aff id="A1">Departments of Psychiatry and Neurology, University of Pittsburgh, 3811 O’Hara St.,<italic>Pittsburgh</italic>
. PA 15213-2582, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>. PA 15213-2582</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Koeppe, Robert A" sort="Koeppe, Robert A" uniqKey="Koeppe R" first="Robert A." last="Koeppe">Robert A. Koeppe</name>
<affiliation wicri:level="1"><nlm:aff id="A2">Department of Radiology, University of Michigan, 1301 E Medical Center Drive, Ann Arbor MI, 48109, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Radiology, University of Michigan, 1301 E Medical Center Drive, Ann Arbor MI, 48109</wicri:regionArea>
<wicri:noRegion>48109</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Price, Julie C" sort="Price, Julie C" uniqKey="Price J" first="Julie C." last="Price">Julie C. Price</name>
<affiliation wicri:level="4"><nlm:aff id="A3">Department of Radiology, University of Pittsburgh, 200 Lothrop St., Pittsburgh, PA 15213-2582, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Radiology, University of Pittsburgh, 200 Lothrop St., Pittsburgh, PA 15213-2582</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">Pittsburgh</settlement>
</placeName>
<orgName type="university">Université de Pittsburgh</orgName>
</affiliation>
</author>
<author><name sortKey="Benzinger, Tammie" sort="Benzinger, Tammie" uniqKey="Benzinger T" first="Tammie" last="Benzinger">Tammie Benzinger</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Departments of Radiology and Neurosurgery, Washington University, Saint Louis, MO, 63110, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Radiology and Neurosurgery, Washington University, Saint Louis, MO, 63110</wicri:regionArea>
<wicri:noRegion>63110</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Devous, Michael D" sort="Devous, Michael D" uniqKey="Devous M" first="Michael D." last="Devous">Michael D. Devous</name>
<affiliation wicri:level="2"><nlm:aff id="A5">Departments of Neurology and Radiology, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9061, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Neurology and Radiology, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9061</wicri:regionArea>
<placeName><region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jagust, William" sort="Jagust, William" uniqKey="Jagust W" first="William" last="Jagust">William Jagust</name>
<affiliation><nlm:aff id="A6">Helen Wills Neuroscience Institute, University of California Berkeley</nlm:aff>
<wicri:noCountry code="subfield">University of California Berkeley</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Johnson, Keith" sort="Johnson, Keith" uniqKey="Johnson K" first="Keith" last="Johnson">Keith Johnson</name>
<affiliation wicri:level="2"><nlm:aff id="A7">Departments of Radiology and Neurology, Massachusetts General Hospital, 33 Fruit St., Boston, MA 02114, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Radiology and Neurology, Massachusetts General Hospital, 33 Fruit St., Boston, MA 02114</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mathis, Chester A" sort="Mathis, Chester A" uniqKey="Mathis C" first="Chester A." last="Mathis">Chester A. Mathis</name>
<affiliation wicri:level="4"><nlm:aff id="A8">Departments of Radiology, Pharmacology and Biological Chemistry, and Pharmaceutical Sciences, University of Pittsburgh, 200 Lothrop St., Pittsburgh, PA 15213-2582, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Radiology, Pharmacology and Biological Chemistry, and Pharmaceutical Sciences, University of Pittsburgh, 200 Lothrop St., Pittsburgh, PA 15213-2582</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">Pittsburgh</settlement>
</placeName>
<orgName type="university">Université de Pittsburgh</orgName>
</affiliation>
</author>
<author><name sortKey="Minhas, Davneet" sort="Minhas, Davneet" uniqKey="Minhas D" first="Davneet" last="Minhas">Davneet Minhas</name>
<affiliation wicri:level="4"><nlm:aff id="A9">Department of Radiology, University of Pittsburgh, 200 Lothrop St., Pittsburgh, PA 15213-2582, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Radiology, University of Pittsburgh, 200 Lothrop St., Pittsburgh, PA 15213-2582</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
<settlement type="city">Pittsburgh</settlement>
</placeName>
<orgName type="university">Université de Pittsburgh</orgName>
</affiliation>
</author>
<author><name sortKey="Pontecorvo, Michael J" sort="Pontecorvo, Michael J" uniqKey="Pontecorvo M" first="Michael J." last="Pontecorvo">Michael J. Pontecorvo</name>
<affiliation wicri:level="2"><nlm:aff id="A10">Avid Radiopharmaceuticals, 3711 Market St., Philadelphia, PA 19104</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>Avid Radiopharmaceuticals, 3711 Market St., Philadelphia</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Rowe, Christopher C" sort="Rowe, Christopher C" uniqKey="Rowe C" first="Christopher C." last="Rowe">Christopher C. Rowe</name>
<affiliation wicri:level="1"><nlm:aff id="A11">Department of Nuclear Medicine and Centre for PET, Austin Health, Melbourne, VIC 3103, Australia</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Nuclear Medicine and Centre for PET, Austin Health, Melbourne, VIC 3103</wicri:regionArea>
<wicri:noRegion>VIC 3103</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Skovronsky, Daniel" sort="Skovronsky, Daniel" uniqKey="Skovronsky D" first="Daniel" last="Skovronsky">Daniel Skovronsky</name>
<affiliation wicri:level="2"><nlm:aff id="A10">Avid Radiopharmaceuticals, 3711 Market St., Philadelphia, PA 19104</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>Avid Radiopharmaceuticals, 3711 Market St., Philadelphia</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Mintun, Mark" sort="Mintun, Mark" uniqKey="Mintun M" first="Mark" last="Mintun">Mark Mintun</name>
<affiliation wicri:level="2"><nlm:aff id="A10">Avid Radiopharmaceuticals, 3711 Market St., Philadelphia, PA 19104</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
<wicri:cityArea>Avid Radiopharmaceuticals, 3711 Market St., Philadelphia</wicri:cityArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Alzheimer's & dementia : the journal of the Alzheimer's Association</title>
<idno type="ISSN">1552-5260</idno>
<idno type="eISSN">1552-5279</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Alzheimer Disease (diagnostic imaging)</term>
<term>Alzheimer Disease (metabolism)</term>
<term>Amyloid (metabolism)</term>
<term>Aniline Compounds</term>
<term>Brain (diagnostic imaging)</term>
<term>Brain (metabolism)</term>
<term>Calibration</term>
<term>Fluorodeoxyglucose F18</term>
<term>Humans</term>
<term>Image Interpretation, Computer-Assisted</term>
<term>Middle Aged</term>
<term>Plaque, Amyloid (diagnostic imaging)</term>
<term>Plaque, Amyloid (metabolism)</term>
<term>Positron-Emission Tomography (standards)</term>
<term>Radiopharmaceuticals</term>
<term>Thiazoles</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Amyloïde (métabolisme)</term>
<term>Calibrage</term>
<term>Dérivés de l'aniline</term>
<term>Encéphale (imagerie diagnostique)</term>
<term>Encéphale (métabolisme)</term>
<term>Fluorodésoxyglucose F18</term>
<term>Humains</term>
<term>Interprétation d'image assistée par ordinateur</term>
<term>Maladie d'Alzheimer (imagerie diagnostique)</term>
<term>Maladie d'Alzheimer (métabolisme)</term>
<term>Plaque amyloïde (imagerie diagnostique)</term>
<term>Plaque amyloïde (métabolisme)</term>
<term>Radiopharmaceutiques</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Thiazoles</term>
<term>Tomographie par émission de positons (normes)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Amyloid</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Alzheimer Disease</term>
<term>Brain</term>
<term>Plaque, Amyloid</term>
</keywords>
<keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Encéphale</term>
<term>Maladie d'Alzheimer</term>
<term>Plaque amyloïde</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Alzheimer Disease</term>
<term>Brain</term>
<term>Plaque, Amyloid</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Amyloïde</term>
<term>Encéphale</term>
<term>Maladie d'Alzheimer</term>
<term>Plaque amyloïde</term>
</keywords>
<keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Tomographie par émission de positons</term>
</keywords>
<keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Positron-Emission Tomography</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Aniline Compounds</term>
<term>Calibration</term>
<term>Fluorodeoxyglucose F18</term>
<term>Humans</term>
<term>Image Interpretation, Computer-Assisted</term>
<term>Middle Aged</term>
<term>Radiopharmaceuticals</term>
<term>Thiazoles</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Calibrage</term>
<term>Dérivés de l'aniline</term>
<term>Fluorodésoxyglucose F18</term>
<term>Humains</term>
<term>Interprétation d'image assistée par ordinateur</term>
<term>Radiopharmaceutiques</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Thiazoles</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">Although amyloid imaging with PiB-PET, and now with F-18-labelled tracers, has produced remarkably consistent qualitative findings across a large number of centers, there has been considerable variability in the exact numbers reported as quantitative outcome measures of tracer retention. In some cases this is as trivial as the choice of units, in some cases it is scanner dependent, and of course, different tracers yield different numbers. Our working group was formed to standardize quantitative amyloid imaging measures by scaling the outcome of each particular analysis method or tracer to a 0 to 100 scale, anchored by young controls (≤45 years) and typical Alzheimer’s disease patients. The units of this scale have been named “Centiloids.” Basically, we describe a “standard” method of analyzing PiB PET data and then a method for scaling any “non-standard” method of PiB PET analysis (or any other tracer) to the Centiloid scale.</p>
</div>
</front>
</TEI>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Amérique/explor/PittsburghV1/Data/Main/Merge

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000F53 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 000F53 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Amérique
   |area=    PittsburghV1
   |flux=    Main
   |étape=   Merge
   |type=    RBID
   |clé=     PMC:4300247
   |texte=   The Centiloid Project: Standardizing Quantitative Amyloid Plaque Estimation by PET
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Merge/RBID.i   -Sk "pubmed:25443857" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Merge/biblio.hfd   \
       | NlmPubMed2Wicri -a PittsburghV1

This area was generated with Dilib version V0.6.38.
Data generation: Fri Jun 18 17:37:45 2021. Site generation: Fri Jun 18 18:15:47 2021

Serveur d'exploration sur Pittsburgh

The Centiloid Project: Standardizing Quantitative Amyloid Plaque Estimation by PET

The Centiloid Project: Standardizing Quantitative Amyloid Plaque Estimation by PET

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur Pittsburgh
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.