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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Emerging Role for rTMS in Optimizing the Treatment of Adolescent Depression</title><author><name sortKey="Croarkin, Paul E" sort="Croarkin, Paul E" uniqKey="Croarkin P" first="Paul E." last="Croarkin">Paul E. Croarkin</name><affiliation><nlm:aff id="A1"> Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA</nlm:aff></affiliation></author><author><name sortKey="Wall, Christopher A" sort="Wall, Christopher A" uniqKey="Wall C" first="Christopher A." last="Wall">Christopher A. Wall</name><affiliation><nlm:aff id="A2"> Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Mcclintock, Shawn M" sort="Mcclintock, Shawn M" uniqKey="Mcclintock S" first="Shawn M." last="Mcclintock">Shawn M. Mcclintock</name><affiliation><nlm:aff id="A1"> Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA</nlm:aff></affiliation></author><author><name sortKey="Kozel, F Andrew" sort="Kozel, F Andrew" uniqKey="Kozel F" first="F. Andrew" last="Kozel">F. Andrew Kozel</name><affiliation><nlm:aff id="A1"> Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA</nlm:aff></affiliation></author><author><name sortKey="Husain, Mustafa M" sort="Husain, Mustafa M" uniqKey="Husain M" first="Mustafa M." last="Husain">Mustafa M. Husain</name><affiliation><nlm:aff id="A1"> Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA</nlm:aff></affiliation></author><author><name sortKey="Sampson, Shirlene M" sort="Sampson, Shirlene M" uniqKey="Sampson S" first="Shirlene M." last="Sampson">Shirlene M. Sampson</name><affiliation><nlm:aff id="A2"> Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">20418774</idno><idno type="pmc">2933284</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933284</idno><idno type="RBID">PMC:2933284</idno><idno type="doi">10.1097/YCT.0b013e3181dd17eb</idno><date when="2010">2010</date><idno type="wicri:Area/Pmc/Corpus">000226</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000226</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Emerging Role for rTMS in Optimizing the Treatment of Adolescent Depression</title><author><name sortKey="Croarkin, Paul E" sort="Croarkin, Paul E" uniqKey="Croarkin P" first="Paul E." last="Croarkin">Paul E. Croarkin</name><affiliation><nlm:aff id="A1"> Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA</nlm:aff></affiliation></author><author><name sortKey="Wall, Christopher A" sort="Wall, Christopher A" uniqKey="Wall C" first="Christopher A." last="Wall">Christopher A. Wall</name><affiliation><nlm:aff id="A2"> Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author><author><name sortKey="Mcclintock, Shawn M" sort="Mcclintock, Shawn M" uniqKey="Mcclintock S" first="Shawn M." last="Mcclintock">Shawn M. Mcclintock</name><affiliation><nlm:aff id="A1"> Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA</nlm:aff></affiliation></author><author><name sortKey="Kozel, F Andrew" sort="Kozel, F Andrew" uniqKey="Kozel F" first="F. Andrew" last="Kozel">F. Andrew Kozel</name><affiliation><nlm:aff id="A1"> Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA</nlm:aff></affiliation></author><author><name sortKey="Husain, Mustafa M" sort="Husain, Mustafa M" uniqKey="Husain M" first="Mustafa M." last="Husain">Mustafa M. Husain</name><affiliation><nlm:aff id="A1"> Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA</nlm:aff></affiliation></author><author><name sortKey="Sampson, Shirlene M" sort="Sampson, Shirlene M" uniqKey="Sampson S" first="Shirlene M." last="Sampson">Shirlene M. Sampson</name><affiliation><nlm:aff id="A2"> Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff></affiliation></author></analytic><series><title level="j">The journal of ECT</title><idno type="ISSN">1095-0680</idno><idno type="eISSN">1533-4112</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Major depressive disorder (MDD) in adolescents is a common illness and significant public health problem. Treatment is challenging due to recurrences and limited modalities. Selective serotonin reuptake inhibitors (SSRIs) and Cognitive Behavioral Therapy (CBT) are considered the standard of care in severe or treatment resistant MDD in this age group. However, responses to these interventions are often suboptimal. A growing body of research supports the efficacy of repetitive transcranial magnetic stimulation for the treatment of MDD in adults. Induced seizures are a primary safety concern, although this is rare with appropriate precautions. There is, however, limited experience with rTMS as a therapeutic intervention for adolescent psychiatric disturbances. This review will summarize the rTMS efficacy and safety data in adults and describe all published experience with adolescent MDD. Applications in other adolescent psychiatric illnesses such as schizophrenia and attention-deficit/hyperactivity disorder (ADHD) are reviewed. Safety and ethical issues are paramount with investigational treatments in adolescent psychiatric illnesses. However, further research with rTMS in adolescent MDD is imperative to establish standards for optimal stimulation site, treatment parameters, and its role in treatment algorithms. These may diverge from adult data. Early intervention with neuromodulation could also hold the promise of addressing the developmental course of dysfunctional neurocircuitry.</p></div></front></TEI><pmc article-type="research-article" xml:lang="EN"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9808943</journal-id><journal-id journal-id-type="pubmed-jr-id">21011</journal-id><journal-id journal-id-type="nlm-ta">J ECT</journal-id><journal-title>The journal of ECT</journal-title><issn pub-type="ppub">1095-0680</issn><issn pub-type="epub">1533-4112</issn></journal-meta><article-meta><article-id pub-id-type="pmid">20418774</article-id><article-id pub-id-type="pmc">2933284</article-id><article-id pub-id-type="doi">10.1097/YCT.0b013e3181dd17eb</article-id><article-id pub-id-type="manuscript">NIHMS198963</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>The Emerging Role for rTMS in Optimizing the Treatment of Adolescent Depression</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Croarkin</surname><given-names>Paul E.</given-names></name><degrees>D.O.</degrees><xref rid="A1" ref-type="aff">a</xref><xref rid="FN1" ref-type="author-notes">*</xref></contrib><contrib contrib-type="author"><name><surname>Wall</surname><given-names>Christopher A.</given-names></name><degrees>M.D.</degrees><xref rid="A2" ref-type="aff">b</xref></contrib><contrib contrib-type="author"><name><surname>McClintock</surname><given-names>Shawn M.</given-names></name><degrees>Ph.D.</degrees><xref rid="A1" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Kozel</surname><given-names>F. Andrew</given-names></name><degrees>M.D., M.S.C.R.</degrees><xref rid="A1" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Husain</surname><given-names>Mustafa M.</given-names></name><degrees>M.D.</degrees><xref rid="A1" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Sampson</surname><given-names>Shirlene M.</given-names></name><degrees>M.D.</degrees><xref rid="A2" ref-type="aff">b</xref></contrib></contrib-group><aff id="A1"><label>a</label> Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA</aff><aff id="A2"><label>b</label> Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota, USA</aff><author-notes><corresp id="FN1"><label>*</label>Corresponding author: Paul E. Croarkin, D.O., Assistant Professor, Department of Psychiatry, Division of Child and Adolescent Psychiatry, 6330 Harry Hines, Blvd. Suite 12000, Dallas, TX 75235, Phone: (214) 456-4224, Fax: (214) 648-0168, <email>Paul.Croarkin@utsouthwestern.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>6</day><month>5</month><year>2010</year></pub-date><pub-date pub-type="ppub"><month>12</month><year>2010</year></pub-date><pub-date pub-type="pmc-release"><day>1</day><month>12</month><year>2011</year></pub-date><volume>26</volume><issue>4</issue><fpage>323</fpage><lpage>329</lpage><abstract><p id="P1">Major depressive disorder (MDD) in adolescents is a common illness and significant public health problem. Treatment is challenging due to recurrences and limited modalities. Selective serotonin reuptake inhibitors (SSRIs) and Cognitive Behavioral Therapy (CBT) are considered the standard of care in severe or treatment resistant MDD in this age group. However, responses to these interventions are often suboptimal. A growing body of research supports the efficacy of repetitive transcranial magnetic stimulation for the treatment of MDD in adults. Induced seizures are a primary safety concern, although this is rare with appropriate precautions. There is, however, limited experience with rTMS as a therapeutic intervention for adolescent psychiatric disturbances. This review will summarize the rTMS efficacy and safety data in adults and describe all published experience with adolescent MDD. Applications in other adolescent psychiatric illnesses such as schizophrenia and attention-deficit/hyperactivity disorder (ADHD) are reviewed. Safety and ethical issues are paramount with investigational treatments in adolescent psychiatric illnesses. However, further research with rTMS in adolescent MDD is imperative to establish standards for optimal stimulation site, treatment parameters, and its role in treatment algorithms. These may diverge from adult data. Early intervention with neuromodulation could also hold the promise of addressing the developmental course of dysfunctional neurocircuitry.</p></abstract><kwd-group><kwd>transcranial magnetic stimulation</kwd><kwd>adolescents</kwd><kwd>major depressive disorder</kwd></kwd-group><contract-num rid="RR1">UL1 RR024982-03
||RR</contract-num><contract-num rid="MH1">K23 MH070897-04
||MH</contract-num><contract-sponsor id="RR1">National Center for Research Resources : NCRR</contract-sponsor><contract-sponsor id="MH1">National Institute of Mental Health : NIMH</contract-sponsor></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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