Psychosocial treatments for bipolar disorder: cost‐effectiveness, mediating mechanisms, and future directions
Identifieur interne : 000A90 ( Istex/Corpus ); précédent : 000A89; suivant : 000A91Psychosocial treatments for bipolar disorder: cost‐effectiveness, mediating mechanisms, and future directions
Auteurs : David J. Miklowitz ; Jan ScottSource :
- Bipolar Disorders [ 1398-5647 ] ; 2009-06.
English descriptors
- KwdEn :
Abstract
Objectives: Randomized trials of adjunctive psychotherapy for bipolar disorder are reviewed, in tandem with discussion of cost‐effectiveness, mediating mechanisms, and moderators of effects.
Url:
DOI: 10.1111/j.1399-5618.2009.00715.x
Links to Exploration step
ISTEX:95C06B4A6BA24EBB77C1F12974999617BEDD4F16Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Psychosocial treatments for bipolar disorder: cost‐effectiveness, mediating mechanisms, and future directions</title><author><name sortKey="Miklowitz, David J" sort="Miklowitz, David J" uniqKey="Miklowitz D" first="David J" last="Miklowitz">David J. Miklowitz</name><affiliation><mods:affiliation>Departments of Psychology and Psychiatry, University of Colorado, Boulder and Denver, CO, USA</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Psychiatry, Warneford Hospital, Oxford University, Oxford</mods:affiliation></affiliation></author><author><name sortKey="Scott, Jan" sort="Scott, Jan" uniqKey="Scott J" first="Jan" last="Scott">Jan Scott</name><affiliation><mods:affiliation>Department of Psychiatry, University of Newcastle, Newcastle</mods:affiliation></affiliation><affiliation><mods:affiliation>Honorary Professor, Institute of Psychiatry, London, UK</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:95C06B4A6BA24EBB77C1F12974999617BEDD4F16</idno><date when="2009" year="2009">2009</date><idno type="doi">10.1111/j.1399-5618.2009.00715.x</idno><idno type="url">https://api.istex.fr/document/95C06B4A6BA24EBB77C1F12974999617BEDD4F16/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000A90</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000A90</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Psychosocial treatments for bipolar disorder: cost‐effectiveness, mediating mechanisms, and future directions</title><author><name sortKey="Miklowitz, David J" sort="Miklowitz, David J" uniqKey="Miklowitz D" first="David J" last="Miklowitz">David J. Miklowitz</name><affiliation><mods:affiliation>Departments of Psychology and Psychiatry, University of Colorado, Boulder and Denver, CO, USA</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Psychiatry, Warneford Hospital, Oxford University, Oxford</mods:affiliation></affiliation></author><author><name sortKey="Scott, Jan" sort="Scott, Jan" uniqKey="Scott J" first="Jan" last="Scott">Jan Scott</name><affiliation><mods:affiliation>Department of Psychiatry, University of Newcastle, Newcastle</mods:affiliation></affiliation><affiliation><mods:affiliation>Honorary Professor, Institute of Psychiatry, London, UK</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Bipolar Disorders</title><idno type="ISSN">1398-5647</idno><idno type="eISSN">1399-5618</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2009-06">2009-06</date><biblScope unit="volume">11</biblScope><biblScope unit="supplement">s2</biblScope><biblScope unit="page" from="110">110</biblScope><biblScope unit="page" to="122">122</biblScope></imprint><idno type="ISSN">1398-5647</idno></series><idno type="istex">95C06B4A6BA24EBB77C1F12974999617BEDD4F16</idno><idno type="DOI">10.1111/j.1399-5618.2009.00715.x</idno><idno type="ArticleID">BDI715</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1398-5647</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>cognitive‐behavioral therapy</term><term>cost‐effectiveness</term><term>family‐focused therapy</term><term>interpersonal and social rhythm therapy</term><term>psychoeducation</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Objectives: Randomized trials of adjunctive psychotherapy for bipolar disorder are reviewed, in tandem with discussion of cost‐effectiveness, mediating mechanisms, and moderators of effects.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>David J Miklowitz</name><affiliations><json:string>Departments of Psychology and Psychiatry, University of Colorado, Boulder and Denver, CO, USA</json:string><json:string>Department of Psychiatry, Warneford Hospital, Oxford University, Oxford</json:string></affiliations></json:item><json:item><name>Jan Scott</name><affiliations><json:string>Department of Psychiatry, University of Newcastle, Newcastle</json:string><json:string>Honorary Professor, Institute of Psychiatry, London, UK</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>cognitive‐behavioral therapy</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>cost‐effectiveness</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>family‐focused therapy</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>interpersonal and social rhythm therapy</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>psychoeducation</value></json:item></subject><articleId><json:string>BDI715</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>reviewArticle</json:string></originalGenre><qualityIndicators><score>5.276</score><pdfVersion>1.3</pdfVersion><pdfPageSize>595.276 x 782.362 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>191</abstractCharCount><pdfWordCount>8551</pdfWordCount><pdfCharCount>57447</pdfCharCount><pdfPageCount>13</pdfPageCount><abstractWordCount>23</abstractWordCount></qualityIndicators><title>Psychosocial treatments for bipolar disorder: cost‐effectiveness, mediating mechanisms, and future directions</title><genre><json:string>review-article</json:string></genre><host><volume>11</volume><publisherId><json:string>BDI</json:string></publisherId><pages><total>13</total><last>122</last><first>110</first></pages><issn><json:string>1398-5647</json:string></issn><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1399-5618</json:string></eissn><title>Bipolar Disorders</title><doi><json:string>10.1111/(ISSN)1399-5618</json:string></doi></host><categories><wos><json:string>social science</json:string><json:string>psychiatry</json:string><json:string>science</json:string><json:string>neurosciences</json:string><json:string>clinical neurology</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>clinical medicine</json:string><json:string>psychiatry</json:string></scienceMetrix></categories><publicationDate>2009</publicationDate><copyrightDate>2009</copyrightDate><doi><json:string>10.1111/j.1399-5618.2009.00715.x</json:string></doi><id>95C06B4A6BA24EBB77C1F12974999617BEDD4F16</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/95C06B4A6BA24EBB77C1F12974999617BEDD4F16/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/95C06B4A6BA24EBB77C1F12974999617BEDD4F16/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/95C06B4A6BA24EBB77C1F12974999617BEDD4F16/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Psychosocial treatments for bipolar disorder: cost‐effectiveness, mediating mechanisms, and future directions</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><availability><p>© 2009 John Wiley & Sons A/S</p></availability><date>2009</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Psychosocial treatments for bipolar disorder: cost‐effectiveness, mediating mechanisms, and future directions</title><author xml:id="author-1"><persName><forename type="first">David J</forename><surname>Miklowitz</surname></persName><affiliation>Departments of Psychology and Psychiatry, University of Colorado, Boulder and Denver, CO, USA</affiliation><affiliation>Department of Psychiatry, Warneford Hospital, Oxford University, Oxford</affiliation></author><author xml:id="author-2"><persName><forename type="first">Jan</forename><surname>Scott</surname></persName><affiliation>Department of Psychiatry, University of Newcastle, Newcastle</affiliation><affiliation>Honorary Professor, Institute of Psychiatry, London, UK</affiliation></author></analytic><monogr><title level="j">Bipolar Disorders</title><idno type="pISSN">1398-5647</idno><idno type="eISSN">1399-5618</idno><idno type="DOI">10.1111/(ISSN)1399-5618</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2009-06"></date><biblScope unit="volume">11</biblScope><biblScope unit="supplement">s2</biblScope><biblScope unit="page" from="110">110</biblScope><biblScope unit="page" to="122">122</biblScope></imprint></monogr><idno type="istex">95C06B4A6BA24EBB77C1F12974999617BEDD4F16</idno><idno type="DOI">10.1111/j.1399-5618.2009.00715.x</idno><idno type="ArticleID">BDI715</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2009</date></creation><langUsage><language ident="en">en</language></langUsage><abstract><p>Objectives: Randomized trials of adjunctive psychotherapy for bipolar disorder are reviewed, in tandem with discussion of cost‐effectiveness, mediating mechanisms, and moderators of effects.</p></abstract><abstract><p>Methods: Systematic searches of the MEDLINE and PSYCHLIT databases yielded 19 randomized controlled trials of individual family and group therapies. Outcome variables included time to recovery, relapse or recurrence, symptom severity, medication adherence, and psychosocial functioning.</p></abstract><abstract><p>Results: Meta‐analyses consistently show that disorder‐specific psychotherapies [cognitive‐behavioral therapy (CBT), interpersonal, family, and group] augment mood stabilizers in reducing rates of relapse (OR = 0.57; 95% CI: 0.39–0.82) over 1–2 years. Specific mediating mechanisms include, but are not limited to, increasing medication adherence, teaching self‐monitoring and early intervention with emergent episodes, and enhancing interpersonal functioning and family communication. All therapies have strengths and weaknesses. One group psychoeducation trial, demonstrated effect sizes for recurrence that are at least equivalent to individual therapies, but findings await replication. Family interventions have been successfully administered in both single and multi‐family formats, but no studies report the comparative cost‐effectiveness of these formats. The best‐studied psychotherapy modality, CBT, can have beneficial effects on depression, but findings are inconsistent across studies and vary with sample characteristics and comparison treatments.</p></abstract><abstract><p>Conclusions: Adjunctive psychotherapies can be cost‐effective when weighed against observed reductions in recurrence, hospitalization and functional impairments. Future trials need to (i) clarify which populations are most likely to benefit from which strategies; (ii) identify putative mechanisms of action; (iii) systematically evaluate costs, benefits, and generalizability; and (iv) record adverse effects. The application of psychosocial interventions to young‐onset populations deserves further study.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>keywords</head><item><term>cognitive‐behavioral therapy</term></item><item><term>cost‐effectiveness</term></item><item><term>family‐focused therapy</term></item><item><term>interpersonal and social rhythm therapy</term></item><item><term>psychoeducation</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2009-06">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/95C06B4A6BA24EBB77C1F12974999617BEDD4F16/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Publishing Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1399-5618</doi><issn type="print">1398-5647</issn><issn type="electronic">1399-5618</issn><idGroup><id type="product" value="BDI"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="BIPOLAR DISORDERS">Bipolar Disorders</title></titleGroup></publicationMeta><publicationMeta level="part" position="06000"><doi origin="wiley">10.1111/bdi.2009.11.issue-s2</doi><titleGroup><title type="specialIssueTitle">Lithium and the Modern Management of Bipolar Disorder</title></titleGroup><numberingGroup><numbering type="journalVolume" number="11">11</numbering><numbering type="supplement">s2</numbering></numberingGroup><coverDate startDate="2009-06">June 2009</coverDate></publicationMeta><publicationMeta level="unit" type="reviewArticle" position="11" status="forIssue"><doi origin="wiley">10.1111/j.1399-5618.2009.00715.x</doi><idGroup><id type="unit" value="BDI715"></id></idGroup><countGroup><count type="pageTotal" number="13"></count></countGroup><titleGroup><title type="tocHeading1">Review Articles</title></titleGroup><copyright>© 2009 John Wiley & Sons A/S</copyright><eventGroup><event type="firstOnline" date="2009-06-01"></event><event type="publishedOnlineFinalForm" date="2009-06-01"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.5 mode:FullText source:FullText result:FullText" date="2010-04-07"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-25"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-15"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="110">110</numbering><numbering type="pageLast" number="122">122</numbering></numberingGroup><correspondenceTo>Corresponding author:
David J. Miklowitz, Ph.D.
Department of Psychology
University of Colorado
Muenzinger Building
Boulder, CO 80309‐0345, USA
Fax: +1 303 492 2967
e‐mail: <email>miklowitz@colorado.edu</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:BDI.BDI715.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Received 18 November 2008, revised and accepted for publication 5 February 2009</unparsedEditorialHistory><countGroup><count type="figureTotal" number="0"></count><count type="tableTotal" number="2"></count></countGroup><titleGroup><title type="main">Psychosocial treatments for bipolar disorder: cost‐effectiveness, mediating mechanisms, and future directions</title><title type="shortAuthors"><b>Miklowitz and Scott</b></title><title type="short"><b>Psychosocial treatments for bipolar disorder</b></title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1 #a2"><personName><givenNames>David J</givenNames><familyName>Miklowitz</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a3 #a4"><personName><givenNames>Jan</givenNames><familyName>Scott</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1" countryCode="US"><unparsedAffiliation>Departments of Psychology and Psychiatry, University of Colorado, Boulder and Denver, CO, USA</unparsedAffiliation></affiliation><affiliation xml:id="a2"><unparsedAffiliation>Department of Psychiatry, Warneford Hospital, Oxford University, Oxford</unparsedAffiliation></affiliation><affiliation xml:id="a3"><unparsedAffiliation>Department of Psychiatry, University of Newcastle, Newcastle</unparsedAffiliation></affiliation><affiliation xml:id="a4" countryCode="GB"><unparsedAffiliation>Honorary Professor, Institute of Psychiatry, London, UK</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">cognitive‐behavioral therapy</keyword><keyword xml:id="k2">cost‐effectiveness</keyword><keyword xml:id="k3">family‐focused therapy</keyword><keyword xml:id="k4">interpersonal and social rhythm therapy</keyword><keyword xml:id="k5">psychoeducation</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><!-- Miklowitz DJ, Scott J. Psychosocial treatments for bipolar disorder: cost-effectiveness, mediating mechanisms, and future directions.
Bipolar Disord 2009: 11 (Suppl. 2): 110–122.
© 2009 John Wiley & Sons A/S --><p><b>Objectives: </b> Randomized trials of adjunctive psychotherapy for bipolar disorder are reviewed, in tandem with discussion of cost‐effectiveness, mediating mechanisms, and moderators of effects.</p><p><b>Methods: </b> Systematic searches of the MEDLINE and PSYCHLIT databases yielded 19 randomized controlled trials of individual family and group therapies. Outcome variables included time to recovery, relapse or recurrence, symptom severity, medication adherence, and psychosocial functioning.</p><p><b>Results: </b> Meta‐analyses consistently show that disorder‐specific psychotherapies [cognitive‐behavioral therapy (CBT), interpersonal, family, and group] augment mood stabilizers in reducing rates of relapse (OR = 0.57; 95% CI: 0.39–0.82) over 1–2 years. Specific mediating mechanisms include, but are not limited to, increasing medication adherence, teaching self‐monitoring and early intervention with emergent episodes, and enhancing interpersonal functioning and family communication. All therapies have strengths and weaknesses. One group psychoeducation trial, demonstrated effect sizes for recurrence that are at least equivalent to individual therapies, but findings await replication. Family interventions have been successfully administered in both single and multi‐family formats, but no studies report the comparative cost‐effectiveness of these formats. The best‐studied psychotherapy modality, CBT, can have beneficial effects on depression, but findings are inconsistent across studies and vary with sample characteristics and comparison treatments.</p><p><b>Conclusions: </b> Adjunctive psychotherapies can be cost‐effective when weighed against observed reductions in recurrence, hospitalization and functional impairments. Future trials need to (i) clarify which populations are most likely to benefit from which strategies; (ii) identify putative mechanisms of action; (iii) systematically evaluate costs, benefits, and generalizability; and (iv) record adverse effects. The application of psychosocial interventions to young‐onset populations deserves further study.</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1" numbered="no"><p>The authors report no conflicts of interest in connection with this manuscript.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Psychosocial treatments for bipolar disorder: cost‐effectiveness, mediating mechanisms, and future directions</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Psychosocial treatments for bipolar disorder</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Psychosocial treatments for bipolar disorder: cost‐effectiveness, mediating mechanisms, and future directions</title></titleInfo><name type="personal"><namePart type="given">David J</namePart><namePart type="family">Miklowitz</namePart><affiliation>Departments of Psychology and Psychiatry, University of Colorado, Boulder and Denver, CO, USA</affiliation><affiliation>Department of Psychiatry, Warneford Hospital, Oxford University, Oxford</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jan</namePart><namePart type="family">Scott</namePart><affiliation>Department of Psychiatry, University of Newcastle, Newcastle</affiliation><affiliation>Honorary Professor, Institute of Psychiatry, London, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="review-article" displayLabel="reviewArticle"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2009-06</dateIssued><edition>Received 18 November 2008, revised and accepted for publication 5 February 2009</edition><copyrightDate encoding="w3cdtf">2009</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="tables">2</extent></physicalDescription><abstract>Objectives: Randomized trials of adjunctive psychotherapy for bipolar disorder are reviewed, in tandem with discussion of cost‐effectiveness, mediating mechanisms, and moderators of effects.</abstract><abstract>Methods: Systematic searches of the MEDLINE and PSYCHLIT databases yielded 19 randomized controlled trials of individual family and group therapies. Outcome variables included time to recovery, relapse or recurrence, symptom severity, medication adherence, and psychosocial functioning.</abstract><abstract>Results: Meta‐analyses consistently show that disorder‐specific psychotherapies [cognitive‐behavioral therapy (CBT), interpersonal, family, and group] augment mood stabilizers in reducing rates of relapse (OR = 0.57; 95% CI: 0.39–0.82) over 1–2 years. Specific mediating mechanisms include, but are not limited to, increasing medication adherence, teaching self‐monitoring and early intervention with emergent episodes, and enhancing interpersonal functioning and family communication. All therapies have strengths and weaknesses. One group psychoeducation trial, demonstrated effect sizes for recurrence that are at least equivalent to individual therapies, but findings await replication. Family interventions have been successfully administered in both single and multi‐family formats, but no studies report the comparative cost‐effectiveness of these formats. The best‐studied psychotherapy modality, CBT, can have beneficial effects on depression, but findings are inconsistent across studies and vary with sample characteristics and comparison treatments.</abstract><abstract>Conclusions: Adjunctive psychotherapies can be cost‐effective when weighed against observed reductions in recurrence, hospitalization and functional impairments. Future trials need to (i) clarify which populations are most likely to benefit from which strategies; (ii) identify putative mechanisms of action; (iii) systematically evaluate costs, benefits, and generalizability; and (iv) record adverse effects. The application of psychosocial interventions to young‐onset populations deserves further study.</abstract><subject lang="en"><genre>keywords</genre><topic>cognitive‐behavioral therapy</topic><topic>cost‐effectiveness</topic><topic>family‐focused therapy</topic><topic>interpersonal and social rhythm therapy</topic><topic>psychoeducation</topic></subject><relatedItem type="host"><titleInfo><title>Bipolar Disorders</title></titleInfo><genre type="journal">journal</genre><identifier type="ISSN">1398-5647</identifier><identifier type="eISSN">1399-5618</identifier><identifier type="DOI">10.1111/(ISSN)1399-5618</identifier><identifier type="PublisherID">BDI</identifier><part><date>2009</date><detail type="title"><title>Lithium and the Modern Management of Bipolar Disorder</title></detail><detail type="volume"><caption>vol.</caption><number>11</number></detail><detail type="supplement"><caption>Suppl. no.</caption><number>s2</number></detail><extent unit="pages"><start>110</start><end>122</end><total>13</total></extent></part></relatedItem><identifier type="istex">95C06B4A6BA24EBB77C1F12974999617BEDD4F16</identifier><identifier type="DOI">10.1111/j.1399-5618.2009.00715.x</identifier><identifier type="ArticleID">BDI715</identifier><accessCondition type="use and reproduction" contentType="copyright">© 2009 John Wiley & Sons A/S</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Blackwell Publishing Ltd</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Psychologie/explor/TherFamFrancoV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A90 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000A90 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Psychologie
|area= TherFamFrancoV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:95C06B4A6BA24EBB77C1F12974999617BEDD4F16
|texte= Psychosocial treatments for bipolar disorder: cost‐effectiveness, mediating mechanisms, and future directions
}}
| This area was generated with Dilib version V0.6.29. |  |