PittsburghV1, Istex, Corpus, bibRecord, 001B77

Comparison of Splicing Factor 3b Inhibitors in Human Cells

Identifieur interne : 001B77 ( Istex/Corpus ); précédent : 001B76; suivant : 001B78

Comparison of Splicing Factor 3b Inhibitors in Human Cells

Auteurs : Yang Gao ; Andreas Vogt ; Craig J. Forsyth ; Kazunori Koide

Source :

ChemBioChem [ 1439-4227 ] ; 2013-01-02.

RBID : ISTEX:775671D42A5DA324DBC7898E4CC2CD367AA040E7

English descriptors

KwdEn :
- Analogue, Antiproliferative, Assay, Biol, Chem, Chembiochem, Herboxidiene, Inhibitor, Koide, Luciferase, Luciferase activity, Meayamycin, Minigene, Optimal cell density, Separate experiments, Sf3b, Sf3b inhibitors, Spliceostatin, Verlag gmbh, Yoshida.
Teeft :
- Analogue, Antiproliferative, Assay, Biol, Chem, Chembiochem, Herboxidiene, Inhibitor, Koide, Luciferase, Luciferase activity, Meayamycin, Minigene, Optimal cell density, Separate experiments, Sf3b, Sf3b inhibitors, Spliceostatin, Verlag gmbh, Yoshida.

Abstract

Name your splice: FR901464 analogues and herboxidiene inhibit constitutive splicing, most likely by inhibiting spliceosomal subunit SF3b. A parallel comparison of these compounds in a cell‐based assay system showed meayamycin B as the most potent splicing inhibitor among these small molecules.

Url:

https://api.istex.fr/document/775671D42A5DA324DBC7898E4CC2CD367AA040E7/fulltext/pdf

DOI: 10.1002/cbic.201200558

Links to Exploration step

ISTEX:775671D42A5DA324DBC7898E4CC2CD367AA040E7

Le document en format XML

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Comparison of Splicing Factor 3b Inhibitors in Human Cells

Comparison of Splicing Factor 3b Inhibitors in Human Cells

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