Parkinson's disease: a case-control study of occupational and environmental risk factors.
Identifieur interne : 001B90 ( PubMed/Curation ); précédent : 001B89; suivant : 001B91Parkinson's disease: a case-control study of occupational and environmental risk factors.
Auteurs : C. Hertzman [Canada] ; M. Wiens ; D. Bowering ; B. Snow ; D. CalneSource :
- American journal of industrial medicine [ 0271-3586 ] ; 1990.
English descriptors
- KwdEn :
- Aged, Agriculture, British Columbia (epidemiology), Case-Control Studies, Causality, Environmental Exposure, Fruit, Humans, Middle Aged, Occupational Diseases (chemically induced), Occupational Diseases (epidemiology), Parkinson Disease, Secondary (chemically induced), Parkinson Disease, Secondary (epidemiology), Prevalence, Risk Factors, Rural Population, Wood.
- MESH :
- geographic , epidemiology : British Columbia.
- chemically induced : Occupational Diseases, Parkinson Disease, Secondary.
- epidemiology : Occupational Diseases, Parkinson Disease, Secondary.
- Aged, Agriculture, Case-Control Studies, Causality, Environmental Exposure, Fruit, Humans, Middle Aged, Prevalence, Risk Factors, Rural Population, Wood.
Abstract
We compared personal histories of 57 cases and 122 age-matched controls to identify possible environmental determinants of Parkinson's disease (PD). Odds ratios (OR) adjusted for sex, age, and smoking were computed using stepwise logistic regression. We found a statistically significant increased risk for working in orchards (OR = 3.69, p = 0.012, 95% CI = 1.34, 10.27) and a marginally significant increased risk associated with working in planer mills (OR = 4.11, p = 0.065, 95% CI = 0.91, 18.50). A Fisher's exact test of the association between PD development and (1) paraquat contact, and (2) postural tremor gave statistically significant probability estimates of 0.01 and 0.03, respectively. The relative risk of PD decreased with smoking, an inverse relationship supported by many studies.
PubMed: 2305814
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Hertzman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Health Care and Epidemiology, University of British Columbia, Vancouver</wicri:regionArea></affiliation></author><author><name sortKey="Wiens, M" sort="Wiens, M" uniqKey="Wiens M" first="M" last="Wiens">M. Wiens</name></author><author><name sortKey="Bowering, D" sort="Bowering, D" uniqKey="Bowering D" first="D" last="Bowering">D. Bowering</name></author><author><name sortKey="Snow, B" sort="Snow, B" uniqKey="Snow B" first="B" last="Snow">B. Snow</name></author><author><name sortKey="Calne, D" sort="Calne, D" uniqKey="Calne D" first="D" last="Calne">D. Calne</name></author></analytic><series><title level="j">American journal of industrial medicine</title><idno type="ISSN">0271-3586</idno><imprint><date when="1990" type="published">1990</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Agriculture</term><term>British Columbia (epidemiology)</term><term>Case-Control Studies</term><term>Causality</term><term>Environmental Exposure</term><term>Fruit</term><term>Humans</term><term>Middle Aged</term><term>Occupational Diseases (chemically induced)</term><term>Occupational Diseases (epidemiology)</term><term>Parkinson Disease, Secondary (chemically induced)</term><term>Parkinson Disease, Secondary (epidemiology)</term><term>Prevalence</term><term>Risk Factors</term><term>Rural Population</term><term>Wood</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>British Columbia</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Occupational Diseases</term><term>Parkinson Disease, Secondary</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Occupational Diseases</term><term>Parkinson Disease, Secondary</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Agriculture</term><term>Case-Control Studies</term><term>Causality</term><term>Environmental Exposure</term><term>Fruit</term><term>Humans</term><term>Middle Aged</term><term>Prevalence</term><term>Risk Factors</term><term>Rural Population</term><term>Wood</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We compared personal histories of 57 cases and 122 age-matched controls to identify possible environmental determinants of Parkinson's disease (PD). Odds ratios (OR) adjusted for sex, age, and smoking were computed using stepwise logistic regression. We found a statistically significant increased risk for working in orchards (OR = 3.69, p = 0.012, 95% CI = 1.34, 10.27) and a marginally significant increased risk associated with working in planer mills (OR = 4.11, p = 0.065, 95% CI = 0.91, 18.50). A Fisher's exact test of the association between PD development and (1) paraquat contact, and (2) postural tremor gave statistically significant probability estimates of 0.01 and 0.03, respectively. The relative risk of PD decreased with smoking, an inverse relationship supported by many studies.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">2305814</PMID><DateCreated><Year>1990</Year><Month>03</Month><Day>26</Day></DateCreated><DateCompleted><Year>1990</Year><Month>03</Month><Day>26</Day></DateCompleted><DateRevised><Year>2006</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0271-3586</ISSN><JournalIssue CitedMedium="Print"><Volume>17</Volume><Issue>3</Issue><PubDate><Year>1990</Year></PubDate></JournalIssue><Title>American journal of industrial medicine</Title><ISOAbbreviation>Am. J. Ind. Med.</ISOAbbreviation></Journal><ArticleTitle>Parkinson's disease: a case-control study of occupational and environmental risk factors.</ArticleTitle><Pagination><MedlinePgn>349-55</MedlinePgn></Pagination><Abstract><AbstractText>We compared personal histories of 57 cases and 122 age-matched controls to identify possible environmental determinants of Parkinson's disease (PD). Odds ratios (OR) adjusted for sex, age, and smoking were computed using stepwise logistic regression. We found a statistically significant increased risk for working in orchards (OR = 3.69, p = 0.012, 95% CI = 1.34, 10.27) and a marginally significant increased risk associated with working in planer mills (OR = 4.11, p = 0.065, 95% CI = 0.91, 18.50). A Fisher's exact test of the association between PD development and (1) paraquat contact, and (2) postural tremor gave statistically significant probability estimates of 0.01 and 0.03, respectively. The relative risk of PD decreased with smoking, an inverse relationship supported by many studies.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Hertzman</LastName><ForeName>C</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wiens</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Bowering</LastName><ForeName>D</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Snow</LastName><ForeName>B</ForeName><Initials>B</Initials></Author><Author ValidYN="Y"><LastName>Calne</LastName><ForeName>D</ForeName><Initials>D</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Am J Ind Med</MedlineTA><NlmUniqueID>8101110</NlmUniqueID><ISSNLinking>0271-3586</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000383" MajorTopicYN="N">Agriculture</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001955" MajorTopicYN="N" Type="Geographic">British Columbia</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016022" MajorTopicYN="N">Case-Control Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015984" MajorTopicYN="N">Causality</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004781" MajorTopicYN="N">Environmental Exposure</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005638" MajorTopicYN="N">Fruit</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009784" MajorTopicYN="N">Occupational Diseases</DescriptorName><QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010302" MajorTopicYN="N">Parkinson Disease, Secondary</DescriptorName><QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012424" MajorTopicYN="N">Rural Population</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014934" MajorTopicYN="N">Wood</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1990</Year><Month>1</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1990</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1990</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">2305814</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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