Microelectrode recordings in the pallidum.
Identifieur interne : 001537 ( PubMed/Corpus ); précédent : 001536; suivant : 001538Microelectrode recordings in the pallidum.
Auteurs : Andres M. Lozano ; William D. HutchisonSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2002.
English descriptors
- KwdEn :
- MESH :
- instrumentation : Monitoring, Intraoperative.
- methods : Brain Mapping, Monitoring, Intraoperative.
- physiology : Neurons.
- physiopathology : Globus Pallidus.
- surgery : Dystonia, Globus Pallidus, Parkinson Disease.
- Humans, Microelectrodes, Stereotaxic Techniques.
Abstract
The internal segment of the globus pallidus (GPi) is being targeted in neurosurgical procedures to treat Parkinson's disease and dystonia. Precise targeting of the pallidal complex is important in determining the efficacy of the surgical intervention and for the avoidance of adverse effects. Intraoperative microelectrode recording can be used to characterize the patterns of activity and receptive field properties of single pallidal neurons and to identify important bordering structures, including the optic tract and internal capsule. Because the clinical features of movement disorders can be differentially affected as a function of location within the pallidal complex, further refinements in intraoperative targeting may become important.
PubMed: 11948770
Links to Exploration step
pubmed:11948770Le document en format XML
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<author><name sortKey="Lozano, Andres M" sort="Lozano, Andres M" uniqKey="Lozano A" first="Andres M" last="Lozano">Andres M. Lozano</name>
<affiliation><nlm:affiliation>Division of Neurosurgery, University of Toronto, The Toronto Hospital, Western Division, Toronto, Ontario, Canada. lozano@uhnres.utoronto.ca</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hutchison, William D" sort="Hutchison, William D" uniqKey="Hutchison W" first="William D" last="Hutchison">William D. Hutchison</name>
</author>
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<author><name sortKey="Lozano, Andres M" sort="Lozano, Andres M" uniqKey="Lozano A" first="Andres M" last="Lozano">Andres M. Lozano</name>
<affiliation><nlm:affiliation>Division of Neurosurgery, University of Toronto, The Toronto Hospital, Western Division, Toronto, Ontario, Canada. lozano@uhnres.utoronto.ca</nlm:affiliation>
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<author><name sortKey="Hutchison, William D" sort="Hutchison, William D" uniqKey="Hutchison W" first="William D" last="Hutchison">William D. Hutchison</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2002" type="published">2002</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Brain Mapping (methods)</term>
<term>Dystonia (surgery)</term>
<term>Globus Pallidus (physiopathology)</term>
<term>Globus Pallidus (surgery)</term>
<term>Humans</term>
<term>Microelectrodes</term>
<term>Monitoring, Intraoperative (instrumentation)</term>
<term>Monitoring, Intraoperative (methods)</term>
<term>Neurons (physiology)</term>
<term>Parkinson Disease (surgery)</term>
<term>Stereotaxic Techniques</term>
</keywords>
<keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Monitoring, Intraoperative</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Brain Mapping</term>
<term>Monitoring, Intraoperative</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Neurons</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Globus Pallidus</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Dystonia</term>
<term>Globus Pallidus</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Humans</term>
<term>Microelectrodes</term>
<term>Stereotaxic Techniques</term>
</keywords>
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<front><div type="abstract" xml:lang="en">The internal segment of the globus pallidus (GPi) is being targeted in neurosurgical procedures to treat Parkinson's disease and dystonia. Precise targeting of the pallidal complex is important in determining the efficacy of the surgical intervention and for the avoidance of adverse effects. Intraoperative microelectrode recording can be used to characterize the patterns of activity and receptive field properties of single pallidal neurons and to identify important bordering structures, including the optic tract and internal capsule. Because the clinical features of movement disorders can be differentially affected as a function of location within the pallidal complex, further refinements in intraoperative targeting may become important.</div>
</front>
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<DateCreated><Year>2002</Year>
<Month>04</Month>
<Day>11</Day>
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<DateCompleted><Year>2002</Year>
<Month>05</Month>
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<DateRevised><Year>2004</Year>
<Month>11</Month>
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<Article PubModel="Print"><Journal><ISSN IssnType="Print">0885-3185</ISSN>
<JournalIssue CitedMedium="Print"><Volume>17 Suppl 3</Volume>
<PubDate><Year>2002</Year>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
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<ArticleTitle>Microelectrode recordings in the pallidum.</ArticleTitle>
<Pagination><MedlinePgn>S150-4</MedlinePgn>
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<Abstract><AbstractText>The internal segment of the globus pallidus (GPi) is being targeted in neurosurgical procedures to treat Parkinson's disease and dystonia. Precise targeting of the pallidal complex is important in determining the efficacy of the surgical intervention and for the avoidance of adverse effects. Intraoperative microelectrode recording can be used to characterize the patterns of activity and receptive field properties of single pallidal neurons and to identify important bordering structures, including the optic tract and internal capsule. Because the clinical features of movement disorders can be differentially affected as a function of location within the pallidal complex, further refinements in intraoperative targeting may become important.</AbstractText>
<CopyrightInformation>Copyright 2002 Movement Disorder Society</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lozano</LastName>
<ForeName>Andres M</ForeName>
<Initials>AM</Initials>
<AffiliationInfo><Affiliation>Division of Neurosurgery, University of Toronto, The Toronto Hospital, Western Division, Toronto, Ontario, Canada. lozano@uhnres.utoronto.ca</Affiliation>
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<Author ValidYN="Y"><LastName>Hutchison</LastName>
<ForeName>William D</ForeName>
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<Language>eng</Language>
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<MedlineTA>Mov Disord</MedlineTA>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D001931" MajorTopicYN="N">Brain Mapping</DescriptorName>
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<MeshHeading><DescriptorName UI="D004421" MajorTopicYN="N">Dystonia</DescriptorName>
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<MeshHeading><DescriptorName UI="D005917" MajorTopicYN="N">Globus Pallidus</DescriptorName>
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<QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName>
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<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<MeshHeading><DescriptorName UI="D008839" MajorTopicYN="N">Microelectrodes</DescriptorName>
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<MeshHeading><DescriptorName UI="D016343" MajorTopicYN="N">Monitoring, Intraoperative</DescriptorName>
<QualifierName UI="Q000295" MajorTopicYN="N">instrumentation</QualifierName>
<QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName>
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<MeshHeading><DescriptorName UI="D009474" MajorTopicYN="N">Neurons</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
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<MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName>
<QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013238" MajorTopicYN="Y">Stereotaxic Techniques</DescriptorName>
</MeshHeading>
</MeshHeadingList>
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