Frontal-striatal circuit functions: context, sequence, and consequence.
Identifieur interne : 001471 ( PubMed/Corpus ); précédent : 001470; suivant : 001472Frontal-striatal circuit functions: context, sequence, and consequence.
Auteurs : Jean A. Saint-CyrSource :
- Journal of the International Neuropsychological Society : JINS [ 1355-6177 ] ; 2003.
English descriptors
- KwdEn :
- Basal Ganglia (metabolism), Basal Ganglia (physiopathology), Cognition Disorders (diagnosis), Cognition Disorders (physiopathology), Corpus Striatum (metabolism), Corpus Striatum (physiopathology), Dopamine (metabolism), Frontal Lobe (metabolism), Frontal Lobe (physiopathology), Humans, Neuropsychological Tests, Parkinson Disease (metabolism), Parkinson Disease (physiopathology), gamma-Aminobutyric Acid (metabolism).
- MESH :
- chemical , metabolism : Dopamine, gamma-Aminobutyric Acid.
- diagnosis : Cognition Disorders.
- metabolism : Basal Ganglia, Corpus Striatum, Frontal Lobe, Parkinson Disease.
- physiopathology : Basal Ganglia, Cognition Disorders, Corpus Striatum, Frontal Lobe, Parkinson Disease.
- Humans, Neuropsychological Tests.
Abstract
The exact role of the basal ganglia in both the motor and non-motor domains has proven elusive since it is virtually impossible to refer to its function in isolation of cortical, and especially frontal cortical circuits. The result is that we often speak of frontal-striatal circuits and functions but this still leaves us in the dark when trying to specify basal ganglia information processing. A critical review of the data from both basic science and clinical studies suggests that we should break down processing along a temporal continuum, including the domains of context, sequential information processing, and feedback or reinforcement (i.e., the consequences of action). This analysis would cut across other theoretical constructs, such as attention, central executive, memory, and learning functions, traditionally employed in the neuropsychological literature. Under specified behavioral constraint, the basal ganglia can then be seen to be involved in fundamental aspects of attentional control (often covert), in the guidance of the early stages of learning (especially reinforcement-based, but also encoding strategies in explicit paradigms), and in the associative binding of reward to cue salience and response sequences via dopaminergic mechanisms. Parkinson's disease is considered to offer only a limited view of basal ganglia function due to partial striatal depletion of dopamine and the potential involvement of other structures and transmitters in its pathology. It is hoped that the present formulation will suggest new heuristic research strategies for basal ganglia research, permitting a closer link to be established between neurophysiological, functional imaging and neuropsychological paradigms.
PubMed: 12570364
Links to Exploration step
pubmed:12570364Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Frontal-striatal circuit functions: context, sequence, and consequence.</title>
<author><name sortKey="Saint Cyr, Jean A" sort="Saint Cyr, Jean A" uniqKey="Saint Cyr J" first="Jean A" last="Saint-Cyr">Jean A. Saint-Cyr</name>
<affiliation><nlm:affiliation>Department of Surgery (Division of Neurosurgery), University of Toronto, ON, Canada. jean@uhnres.utoronto.ca</nlm:affiliation>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2003">2003</date>
<idno type="RBID">pubmed:12570364</idno>
<idno type="pmid">12570364</idno>
<idno type="wicri:Area/PubMed/Corpus">001471</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001471</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Frontal-striatal circuit functions: context, sequence, and consequence.</title>
<author><name sortKey="Saint Cyr, Jean A" sort="Saint Cyr, Jean A" uniqKey="Saint Cyr J" first="Jean A" last="Saint-Cyr">Jean A. Saint-Cyr</name>
<affiliation><nlm:affiliation>Department of Surgery (Division of Neurosurgery), University of Toronto, ON, Canada. jean@uhnres.utoronto.ca</nlm:affiliation>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of the International Neuropsychological Society : JINS</title>
<idno type="ISSN">1355-6177</idno>
<imprint><date when="2003" type="published">2003</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Basal Ganglia (metabolism)</term>
<term>Basal Ganglia (physiopathology)</term>
<term>Cognition Disorders (diagnosis)</term>
<term>Cognition Disorders (physiopathology)</term>
<term>Corpus Striatum (metabolism)</term>
<term>Corpus Striatum (physiopathology)</term>
<term>Dopamine (metabolism)</term>
<term>Frontal Lobe (metabolism)</term>
<term>Frontal Lobe (physiopathology)</term>
<term>Humans</term>
<term>Neuropsychological Tests</term>
<term>Parkinson Disease (metabolism)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>gamma-Aminobutyric Acid (metabolism)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Dopamine</term>
<term>gamma-Aminobutyric Acid</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Cognition Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Basal Ganglia</term>
<term>Corpus Striatum</term>
<term>Frontal Lobe</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Basal Ganglia</term>
<term>Cognition Disorders</term>
<term>Corpus Striatum</term>
<term>Frontal Lobe</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Humans</term>
<term>Neuropsychological Tests</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The exact role of the basal ganglia in both the motor and non-motor domains has proven elusive since it is virtually impossible to refer to its function in isolation of cortical, and especially frontal cortical circuits. The result is that we often speak of frontal-striatal circuits and functions but this still leaves us in the dark when trying to specify basal ganglia information processing. A critical review of the data from both basic science and clinical studies suggests that we should break down processing along a temporal continuum, including the domains of context, sequential information processing, and feedback or reinforcement (i.e., the consequences of action). This analysis would cut across other theoretical constructs, such as attention, central executive, memory, and learning functions, traditionally employed in the neuropsychological literature. Under specified behavioral constraint, the basal ganglia can then be seen to be involved in fundamental aspects of attentional control (often covert), in the guidance of the early stages of learning (especially reinforcement-based, but also encoding strategies in explicit paradigms), and in the associative binding of reward to cue salience and response sequences via dopaminergic mechanisms. Parkinson's disease is considered to offer only a limited view of basal ganglia function due to partial striatal depletion of dopamine and the potential involvement of other structures and transmitters in its pathology. It is hoped that the present formulation will suggest new heuristic research strategies for basal ganglia research, permitting a closer link to be established between neurophysiological, functional imaging and neuropsychological paradigms.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">12570364</PMID>
<DateCreated><Year>2003</Year>
<Month>02</Month>
<Day>06</Day>
</DateCreated>
<DateCompleted><Year>2003</Year>
<Month>03</Month>
<Day>21</Day>
</DateCompleted>
<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">1355-6177</ISSN>
<JournalIssue CitedMedium="Print"><Volume>9</Volume>
<Issue>1</Issue>
<PubDate><Year>2003</Year>
<Month>Jan</Month>
</PubDate>
</JournalIssue>
<Title>Journal of the International Neuropsychological Society : JINS</Title>
<ISOAbbreviation>J Int Neuropsychol Soc</ISOAbbreviation>
</Journal>
<ArticleTitle>Frontal-striatal circuit functions: context, sequence, and consequence.</ArticleTitle>
<Pagination><MedlinePgn>103-27</MedlinePgn>
</Pagination>
<Abstract><AbstractText>The exact role of the basal ganglia in both the motor and non-motor domains has proven elusive since it is virtually impossible to refer to its function in isolation of cortical, and especially frontal cortical circuits. The result is that we often speak of frontal-striatal circuits and functions but this still leaves us in the dark when trying to specify basal ganglia information processing. A critical review of the data from both basic science and clinical studies suggests that we should break down processing along a temporal continuum, including the domains of context, sequential information processing, and feedback or reinforcement (i.e., the consequences of action). This analysis would cut across other theoretical constructs, such as attention, central executive, memory, and learning functions, traditionally employed in the neuropsychological literature. Under specified behavioral constraint, the basal ganglia can then be seen to be involved in fundamental aspects of attentional control (often covert), in the guidance of the early stages of learning (especially reinforcement-based, but also encoding strategies in explicit paradigms), and in the associative binding of reward to cue salience and response sequences via dopaminergic mechanisms. Parkinson's disease is considered to offer only a limited view of basal ganglia function due to partial striatal depletion of dopamine and the potential involvement of other structures and transmitters in its pathology. It is hoped that the present formulation will suggest new heuristic research strategies for basal ganglia research, permitting a closer link to be established between neurophysiological, functional imaging and neuropsychological paradigms.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Saint-Cyr</LastName>
<ForeName>Jean A</ForeName>
<Initials>JA</Initials>
<AffiliationInfo><Affiliation>Department of Surgery (Division of Neurosurgery), University of Toronto, ON, Canada. jean@uhnres.utoronto.ca</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
<PublicationType UI="D016454">Review</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>J Int Neuropsychol Soc</MedlineTA>
<NlmUniqueID>9503760</NlmUniqueID>
<ISSNLinking>1355-6177</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>56-12-2</RegistryNumber>
<NameOfSubstance UI="D005680">gamma-Aminobutyric Acid</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>VTD58H1Z2X</RegistryNumber>
<NameOfSubstance UI="D004298">Dopamine</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList><CommentsCorrections RefType="ErratumIn"><RefSource>J Int Neuropsychol Soc. 2003 Mar;9(3):502.</RefSource>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList><MeshHeading><DescriptorName UI="D001479" MajorTopicYN="N">Basal Ganglia</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003072" MajorTopicYN="N">Cognition Disorders</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003342" MajorTopicYN="N">Corpus Striatum</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004298" MajorTopicYN="N">Dopamine</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005625" MajorTopicYN="N">Frontal Lobe</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009483" MajorTopicYN="N">Neuropsychological Tests</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005680" MajorTopicYN="N">gamma-Aminobutyric Acid</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
</MeshHeadingList>
<NumberOfReferences>318</NumberOfReferences>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2003</Year>
<Month>2</Month>
<Day>7</Day>
<Hour>4</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2003</Year>
<Month>3</Month>
<Day>22</Day>
<Hour>4</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2003</Year>
<Month>2</Month>
<Day>7</Day>
<Hour>4</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">12570364</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001471 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 001471 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Canada |area= ParkinsonCanadaV1 |flux= PubMed |étape= Corpus |type= RBID |clé= pubmed:12570364 |texte= Frontal-striatal circuit functions: context, sequence, and consequence. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:12570364" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \ | NlmPubMed2Wicri -a ParkinsonCanadaV1
![]() | This area was generated with Dilib version V0.6.29. | ![]() |