Burden of parkinsonism: a population-based study.
Identifieur interne : 001450 ( PubMed/Corpus ); précédent : 001449; suivant : 001451Burden of parkinsonism: a population-based study.
Auteurs : Mark Guttman ; Pamela M. Slaughter ; Marc-Erick Theriault ; Donald P. Deboer ; C David NaylorSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2003.
English descriptors
- KwdEn :
- Adult, Aged, Canada (epidemiology), Cohort Studies, Costs and Cost Analysis, Female, Health Services Research, Hospitalization (economics), Hospitalization (statistics & numerical data), Humans, Male, Middle Aged, Office Visits (economics), Office Visits (statistics & numerical data), Parkinson Disease (economics), Parkinson Disease (epidemiology), Parkinson Disease (therapy), Parkinsonian Disorders (economics), Parkinsonian Disorders (epidemiology), Parkinsonian Disorders (therapy), Prevalence.
- MESH :
- geographic , epidemiology : Canada.
- economics : Hospitalization, Office Visits, Parkinson Disease, Parkinsonian Disorders.
- epidemiology : Parkinson Disease, Parkinsonian Disorders.
- statistics & numerical data : Hospitalization, Office Visits.
- therapy : Parkinson Disease, Parkinsonian Disorders.
- Adult, Aged, Cohort Studies, Costs and Cost Analysis, Female, Health Services Research, Humans, Male, Middle Aged, Prevalence.
Abstract
Parkinson's disease (PD) is associated with a significant burden of illness and cost to society, which has been difficult to quantify. Our objective was to use linked administrative databases from the population of Ontario, Canada, to assess the prevalence of parkinsonism, physician- and drug-related costs, and hospital utilization for parkinsonian patients compared with age/sex matched controls. An inception cohort of parkinsonian cases from 1993/1994 was age and sex matched (1:2) to controls and followed for 6 years. Patients were identified by the diagnostic code for PD, the use of specific PD drugs, or a combination. The parkinsonian case cohort (15,304) was matched to (30,608) controls that did not have parkinsonism. The age-adjusted prevalence rates were 3.63 for men and for 3.24 women per 1,000 (increased by 5.4% for men and 9.8% for women). Physician costs were 1.4 times more, there were 1.44 times more hospital admissions, admissions were on average 1.19 times longer, and drug costs were 3.0 times more for parkinsonian cases. We conclude that the substantially higher physician and drug costs as well as hospitalization rates compared with controls clearly suggest that parkinsonism is associated with large direct costs to society.
DOI: 10.1002/mds.10333
PubMed: 12621635
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pubmed:12621635Le document en format XML
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Deboer</name></author><author><name sortKey="Naylor, C David" sort="Naylor, C David" uniqKey="Naylor C" first="C David" last="Naylor">C David Naylor</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2003">2003</date><idno type="RBID">pubmed:12621635</idno><idno type="pmid">12621635</idno><idno type="doi">10.1002/mds.10333</idno><idno type="wicri:Area/PubMed/Corpus">001450</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001450</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Burden of parkinsonism: a population-based study.</title><author><name sortKey="Guttman, Mark" sort="Guttman, Mark" uniqKey="Guttman M" first="Mark" last="Guttman">Mark Guttman</name><affiliation><nlm:affiliation>Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada. mguttman@idirect.com</nlm:affiliation></affiliation></author><author><name sortKey="Slaughter, Pamela M" sort="Slaughter, Pamela M" uniqKey="Slaughter P" first="Pamela M" last="Slaughter">Pamela M. Slaughter</name></author><author><name sortKey="Theriault, Marc Erick" sort="Theriault, Marc Erick" uniqKey="Theriault M" first="Marc-Erick" last="Theriault">Marc-Erick Theriault</name></author><author><name sortKey="Deboer, Donald P" sort="Deboer, Donald P" uniqKey="Deboer D" first="Donald P" last="Deboer">Donald P. Deboer</name></author><author><name sortKey="Naylor, C David" sort="Naylor, C David" uniqKey="Naylor C" first="C David" last="Naylor">C David Naylor</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2003" type="published">2003</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Canada (epidemiology)</term><term>Cohort Studies</term><term>Costs and Cost Analysis</term><term>Female</term><term>Health Services Research</term><term>Hospitalization (economics)</term><term>Hospitalization (statistics & numerical data)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Office Visits (economics)</term><term>Office Visits (statistics & numerical data)</term><term>Parkinson Disease (economics)</term><term>Parkinson Disease (epidemiology)</term><term>Parkinson Disease (therapy)</term><term>Parkinsonian Disorders (economics)</term><term>Parkinsonian Disorders (epidemiology)</term><term>Parkinsonian Disorders (therapy)</term><term>Prevalence</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Canada</term></keywords><keywords scheme="MESH" qualifier="economics" xml:lang="en"><term>Hospitalization</term><term>Office Visits</term><term>Parkinson Disease</term><term>Parkinsonian Disorders</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Parkinson Disease</term><term>Parkinsonian Disorders</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Hospitalization</term><term>Office Visits</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Parkinson Disease</term><term>Parkinsonian Disorders</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Cohort Studies</term><term>Costs and Cost Analysis</term><term>Female</term><term>Health Services Research</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Prevalence</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Parkinson's disease (PD) is associated with a significant burden of illness and cost to society, which has been difficult to quantify. Our objective was to use linked administrative databases from the population of Ontario, Canada, to assess the prevalence of parkinsonism, physician- and drug-related costs, and hospital utilization for parkinsonian patients compared with age/sex matched controls. An inception cohort of parkinsonian cases from 1993/1994 was age and sex matched (1:2) to controls and followed for 6 years. Patients were identified by the diagnostic code for PD, the use of specific PD drugs, or a combination. The parkinsonian case cohort (15,304) was matched to (30,608) controls that did not have parkinsonism. The age-adjusted prevalence rates were 3.63 for men and for 3.24 women per 1,000 (increased by 5.4% for men and 9.8% for women). Physician costs were 1.4 times more, there were 1.44 times more hospital admissions, admissions were on average 1.19 times longer, and drug costs were 3.0 times more for parkinsonian cases. We conclude that the substantially higher physician and drug costs as well as hospitalization rates compared with controls clearly suggest that parkinsonism is associated with large direct costs to society.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">12621635</PMID><DateCreated><Year>2003</Year><Month>03</Month><Day>06</Day></DateCreated><DateCompleted><Year>2003</Year><Month>06</Month><Day>17</Day></DateCompleted><DateRevised><Year>2006</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0885-3185</ISSN><JournalIssue CitedMedium="Print"><Volume>18</Volume><Issue>3</Issue><PubDate><Year>2003</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Burden of parkinsonism: a population-based study.</ArticleTitle><Pagination><MedlinePgn>313-9</MedlinePgn></Pagination><Abstract><AbstractText>Parkinson's disease (PD) is associated with a significant burden of illness and cost to society, which has been difficult to quantify. Our objective was to use linked administrative databases from the population of Ontario, Canada, to assess the prevalence of parkinsonism, physician- and drug-related costs, and hospital utilization for parkinsonian patients compared with age/sex matched controls. An inception cohort of parkinsonian cases from 1993/1994 was age and sex matched (1:2) to controls and followed for 6 years. Patients were identified by the diagnostic code for PD, the use of specific PD drugs, or a combination. The parkinsonian case cohort (15,304) was matched to (30,608) controls that did not have parkinsonism. The age-adjusted prevalence rates were 3.63 for men and for 3.24 women per 1,000 (increased by 5.4% for men and 9.8% for women). Physician costs were 1.4 times more, there were 1.44 times more hospital admissions, admissions were on average 1.19 times longer, and drug costs were 3.0 times more for parkinsonian cases. We conclude that the substantially higher physician and drug costs as well as hospitalization rates compared with controls clearly suggest that parkinsonism is associated with large direct costs to society.</AbstractText><CopyrightInformation>Copyright 2002 Movement Disorder Society</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Guttman</LastName><ForeName>Mark</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada. mguttman@idirect.com</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Slaughter</LastName><ForeName>Pamela M</ForeName><Initials>PM</Initials></Author><Author ValidYN="Y"><LastName>Theriault</LastName><ForeName>Marc-Erick</ForeName><Initials>ME</Initials></Author><Author ValidYN="Y"><LastName>DeBoer</LastName><ForeName>Donald P</ForeName><Initials>DP</Initials></Author><Author ValidYN="Y"><LastName>Naylor</LastName><ForeName>C David</ForeName><Initials>CD</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002170" MajorTopicYN="N" Type="Geographic">Canada</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003365" MajorTopicYN="N">Costs and Cost Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006302" MajorTopicYN="N">Health Services Research</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName><QualifierName UI="Q000191" MajorTopicYN="N">economics</QualifierName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009819" MajorTopicYN="N">Office Visits</DescriptorName><QualifierName UI="Q000191" MajorTopicYN="N">economics</QualifierName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName><QualifierName UI="Q000191" MajorTopicYN="N">economics</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020734" MajorTopicYN="N">Parkinsonian Disorders</DescriptorName><QualifierName UI="Q000191" MajorTopicYN="Y">economics</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2003</Year><Month>3</Month><Day>7</Day><Hour>4</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2003</Year><Month>6</Month><Day>18</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2003</Year><Month>3</Month><Day>7</Day><Hour>4</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">12621635</ArticleId><ArticleId IdType="doi">10.1002/mds.10333</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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