Criteria for deep-brain stimulation in Parkinson's disease: review and analysis.
Identifieur interne : 001134 ( PubMed/Corpus ); précédent : 001133; suivant : 001135Criteria for deep-brain stimulation in Parkinson's disease: review and analysis.
Auteurs : Elena Moro ; Anthony E. LangSource :
- Expert review of neurotherapeutics [ 1744-8360 ] ; 2006.
English descriptors
- KwdEn :
- MESH :
- adverse effects : Deep Brain Stimulation.
- etiology : Mental Disorders.
- methods : Deep Brain Stimulation.
- prevention & control : Mental Disorders.
- therapy : Parkinson Disease.
- trends : Deep Brain Stimulation.
- Humans, Patient Selection, Practice Guidelines as Topic, Practice Patterns, Physicians'.
Abstract
Deep-brain stimulation is currently the most effective surgical treatment for advanced Parkinson's disease. The relevant targets to date are the subthalamic nucleus and the globus pallidus internus, although the thalamus (ventralis intermedius nucleus) is preferred in tremor-dominant, aged Parkinson's disease patients. Long-term benefit in cardinal parkinsonian signs, motor fluctuations and dyskinesia has been reported in 5-year follow-up studies of subthalamic nucleus deep-brain stimulation. However, some psychiatric consequences have raised important issues and emphasized the need for an experienced deep-brain stimulation surgical team. This team should be multidisciplinary and involve movement disorder neurologists, neurosurgeons, neuropsychologists and psychiatrists. The recent observation that deep-brain stimulation of the pedunculopontine nucleus improves axial signs, possibly even in those less responsive to levodopa, brings new hope to the management of advanced Parkinson's disease.
DOI: 10.1586/14737175.6.11.1695
PubMed: 17144783
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pubmed:17144783Le document en format XML
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<term>Humans</term>
<term>Mental Disorders (etiology)</term>
<term>Mental Disorders (prevention & control)</term>
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<keywords scheme="MESH" qualifier="trends" xml:lang="en"><term>Deep Brain Stimulation</term>
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<keywords scheme="MESH" xml:lang="en"><term>Humans</term>
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<front><div type="abstract" xml:lang="en">Deep-brain stimulation is currently the most effective surgical treatment for advanced Parkinson's disease. The relevant targets to date are the subthalamic nucleus and the globus pallidus internus, although the thalamus (ventralis intermedius nucleus) is preferred in tremor-dominant, aged Parkinson's disease patients. Long-term benefit in cardinal parkinsonian signs, motor fluctuations and dyskinesia has been reported in 5-year follow-up studies of subthalamic nucleus deep-brain stimulation. However, some psychiatric consequences have raised important issues and emphasized the need for an experienced deep-brain stimulation surgical team. This team should be multidisciplinary and involve movement disorder neurologists, neurosurgeons, neuropsychologists and psychiatrists. The recent observation that deep-brain stimulation of the pedunculopontine nucleus improves axial signs, possibly even in those less responsive to levodopa, brings new hope to the management of advanced Parkinson's disease.</div>
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<Abstract><AbstractText>Deep-brain stimulation is currently the most effective surgical treatment for advanced Parkinson's disease. The relevant targets to date are the subthalamic nucleus and the globus pallidus internus, although the thalamus (ventralis intermedius nucleus) is preferred in tremor-dominant, aged Parkinson's disease patients. Long-term benefit in cardinal parkinsonian signs, motor fluctuations and dyskinesia has been reported in 5-year follow-up studies of subthalamic nucleus deep-brain stimulation. However, some psychiatric consequences have raised important issues and emphasized the need for an experienced deep-brain stimulation surgical team. This team should be multidisciplinary and involve movement disorder neurologists, neurosurgeons, neuropsychologists and psychiatrists. The recent observation that deep-brain stimulation of the pedunculopontine nucleus improves axial signs, possibly even in those less responsive to levodopa, brings new hope to the management of advanced Parkinson's disease.</AbstractText>
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