Intact encoding, impaired consolidation in procedural learning in Parkinson's disease.
Identifieur interne : 001073 ( PubMed/Corpus ); précédent : 001072; suivant : 001074Intact encoding, impaired consolidation in procedural learning in Parkinson's disease.
Auteurs : Henri Cohen ; Emmanuelle PourcherSource :
- Experimental brain research [ 0014-4819 ] ; 2007.
English descriptors
- KwdEn :
- Brain (metabolism), Brain (physiopathology), Dopamine (deficiency), Female, Humans, Language Tests, Learning, Learning Disorders (etiology), Learning Disorders (physiopathology), Learning Disorders (psychology), Male, Memory Disorders (etiology), Memory Disorders (physiopathology), Memory Disorders (psychology), Middle Aged, Neural Pathways (metabolism), Neural Pathways (physiopathology), Neuropsychological Tests, Parkinson Disease (complications), Parkinson Disease (physiopathology), Parkinson Disease (psychology).
- MESH :
- chemical , deficiency : Dopamine.
- complications : Parkinson Disease.
- etiology : Learning Disorders, Memory Disorders.
- metabolism : Brain, Neural Pathways.
- physiopathology : Brain, Learning Disorders, Memory Disorders, Neural Pathways, Parkinson Disease.
- psychology : Learning Disorders, Memory Disorders, Parkinson Disease.
- Female, Humans, Language Tests, Learning, Male, Middle Aged, Neuropsychological Tests.
Abstract
Idiopathic Parkinson's disease (IPD) patients and matched healthy participants were compared on a non-motor procedural task involving semantically related inverted word pairs, and 3 months later to determine the extent of skill consolidation. IPD patients were found to acquire new procedural skills necessary to read these inverted words, thus indicating that they are not impaired in all types of procedural learning. However, results on post-tests 3 months later, revealed significant group differences with IPD subjects showing little off-line learning relative to the controls. This suggests that a dopamine (DA)-deafferented neural system is not consolidated in the same way that a normally DA-innervated system is, and that impaired maintenance of procedures and routines may place IPD patients in a situation of constant relearning of embedded strategies in motor and non-motor domains.
DOI: 10.1007/s00221-006-0827-6
PubMed: 17279386
Links to Exploration step
pubmed:17279386Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Intact encoding, impaired consolidation in procedural learning in Parkinson's disease.</title>
<author><name sortKey="Cohen, Henri" sort="Cohen, Henri" uniqKey="Cohen H" first="Henri" last="Cohen">Henri Cohen</name>
<affiliation><nlm:affiliation>Cognitive Neuroscience Center, Université du Québec à Montréal and Laboratoire Psychologie et Neurosciences Cognitives, CNRS-Paris Descartes, Stn. Centre-Ville, PB 8888, Montréal, QC, H3C 3P8 Canada. henri.cohen@uqam.ca</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pourcher, Emmanuelle" sort="Pourcher, Emmanuelle" uniqKey="Pourcher E" first="Emmanuelle" last="Pourcher">Emmanuelle Pourcher</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2007">2007</date>
<idno type="RBID">pubmed:17279386</idno>
<idno type="pmid">17279386</idno>
<idno type="doi">10.1007/s00221-006-0827-6</idno>
<idno type="wicri:Area/PubMed/Corpus">001073</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001073</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Intact encoding, impaired consolidation in procedural learning in Parkinson's disease.</title>
<author><name sortKey="Cohen, Henri" sort="Cohen, Henri" uniqKey="Cohen H" first="Henri" last="Cohen">Henri Cohen</name>
<affiliation><nlm:affiliation>Cognitive Neuroscience Center, Université du Québec à Montréal and Laboratoire Psychologie et Neurosciences Cognitives, CNRS-Paris Descartes, Stn. Centre-Ville, PB 8888, Montréal, QC, H3C 3P8 Canada. henri.cohen@uqam.ca</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pourcher, Emmanuelle" sort="Pourcher, Emmanuelle" uniqKey="Pourcher E" first="Emmanuelle" last="Pourcher">Emmanuelle Pourcher</name>
</author>
</analytic>
<series><title level="j">Experimental brain research</title>
<idno type="ISSN">0014-4819</idno>
<imprint><date when="2007" type="published">2007</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Brain (metabolism)</term>
<term>Brain (physiopathology)</term>
<term>Dopamine (deficiency)</term>
<term>Female</term>
<term>Humans</term>
<term>Language Tests</term>
<term>Learning</term>
<term>Learning Disorders (etiology)</term>
<term>Learning Disorders (physiopathology)</term>
<term>Learning Disorders (psychology)</term>
<term>Male</term>
<term>Memory Disorders (etiology)</term>
<term>Memory Disorders (physiopathology)</term>
<term>Memory Disorders (psychology)</term>
<term>Middle Aged</term>
<term>Neural Pathways (metabolism)</term>
<term>Neural Pathways (physiopathology)</term>
<term>Neuropsychological Tests</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson Disease (psychology)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="deficiency" xml:lang="en"><term>Dopamine</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Learning Disorders</term>
<term>Memory Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Brain</term>
<term>Neural Pathways</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Brain</term>
<term>Learning Disorders</term>
<term>Memory Disorders</term>
<term>Neural Pathways</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Learning Disorders</term>
<term>Memory Disorders</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Female</term>
<term>Humans</term>
<term>Language Tests</term>
<term>Learning</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Idiopathic Parkinson's disease (IPD) patients and matched healthy participants were compared on a non-motor procedural task involving semantically related inverted word pairs, and 3 months later to determine the extent of skill consolidation. IPD patients were found to acquire new procedural skills necessary to read these inverted words, thus indicating that they are not impaired in all types of procedural learning. However, results on post-tests 3 months later, revealed significant group differences with IPD subjects showing little off-line learning relative to the controls. This suggests that a dopamine (DA)-deafferented neural system is not consolidated in the same way that a normally DA-innervated system is, and that impaired maintenance of procedures and routines may place IPD patients in a situation of constant relearning of embedded strategies in motor and non-motor domains.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">17279386</PMID>
<DateCreated><Year>2007</Year>
<Month>05</Month>
<Day>22</Day>
</DateCreated>
<DateCompleted><Year>2007</Year>
<Month>10</Month>
<Day>17</Day>
</DateCompleted>
<DateRevised><Year>2013</Year>
<Month>12</Month>
<Day>13</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">0014-4819</ISSN>
<JournalIssue CitedMedium="Print"><Volume>179</Volume>
<Issue>4</Issue>
<PubDate><Year>2007</Year>
<Month>Jun</Month>
</PubDate>
</JournalIssue>
<Title>Experimental brain research</Title>
<ISOAbbreviation>Exp Brain Res</ISOAbbreviation>
</Journal>
<ArticleTitle>Intact encoding, impaired consolidation in procedural learning in Parkinson's disease.</ArticleTitle>
<Pagination><MedlinePgn>703-8</MedlinePgn>
</Pagination>
<Abstract><AbstractText>Idiopathic Parkinson's disease (IPD) patients and matched healthy participants were compared on a non-motor procedural task involving semantically related inverted word pairs, and 3 months later to determine the extent of skill consolidation. IPD patients were found to acquire new procedural skills necessary to read these inverted words, thus indicating that they are not impaired in all types of procedural learning. However, results on post-tests 3 months later, revealed significant group differences with IPD subjects showing little off-line learning relative to the controls. This suggests that a dopamine (DA)-deafferented neural system is not consolidated in the same way that a normally DA-innervated system is, and that impaired maintenance of procedures and routines may place IPD patients in a situation of constant relearning of embedded strategies in motor and non-motor domains.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Cohen</LastName>
<ForeName>Henri</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Cognitive Neuroscience Center, Université du Québec à Montréal and Laboratoire Psychologie et Neurosciences Cognitives, CNRS-Paris Descartes, Stn. Centre-Ville, PB 8888, Montréal, QC, H3C 3P8 Canada. henri.cohen@uqam.ca</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pourcher</LastName>
<ForeName>Emmanuelle</ForeName>
<Initials>E</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2007</Year>
<Month>02</Month>
<Day>06</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Germany</Country>
<MedlineTA>Exp Brain Res</MedlineTA>
<NlmUniqueID>0043312</NlmUniqueID>
<ISSNLinking>0014-4819</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>VTD58H1Z2X</RegistryNumber>
<NameOfSubstance UI="D004298">Dopamine</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D001921" MajorTopicYN="N">Brain</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004298" MajorTopicYN="N">Dopamine</DescriptorName>
<QualifierName UI="Q000172" MajorTopicYN="N">deficiency</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007807" MajorTopicYN="N">Language Tests</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007858" MajorTopicYN="Y">Learning</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007859" MajorTopicYN="N">Learning Disorders</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="Y">psychology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008569" MajorTopicYN="N">Memory Disorders</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009434" MajorTopicYN="N">Neural Pathways</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009483" MajorTopicYN="N">Neuropsychological Tests</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="Y">psychology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2006</Year>
<Month>05</Month>
<Day>03</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2006</Year>
<Month>12</Month>
<Day>12</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2007</Year>
<Month>2</Month>
<Day>7</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2007</Year>
<Month>10</Month>
<Day>18</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2007</Year>
<Month>2</Month>
<Day>7</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">17279386</ArticleId>
<ArticleId IdType="doi">10.1007/s00221-006-0827-6</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001073 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 001073 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Canada |area= ParkinsonCanadaV1 |flux= PubMed |étape= Corpus |type= RBID |clé= pubmed:17279386 |texte= Intact encoding, impaired consolidation in procedural learning in Parkinson's disease. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:17279386" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \ | NlmPubMed2Wicri -a ParkinsonCanadaV1
This area was generated with Dilib version V0.6.29. |